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11/2012
When Darwin introduced natural selection in 1859 as a key mechanism of evolution, little was known about the underlying cause of variation within a species.... 
0984 | Genome assembly | Polymorphism
Dissertation
ISBN 0494794364
When Darwin introduced natural selection in 1859 as a key mechanism of evolution, little was known about the underlying cause of variation within a species.... 
Biology, Bioinformatics | Computer Science
eBook
Bioinformatics, ISSN 1367-4803, 02/2013, Volume 29, Issue 4, pp. 428 - 434
Results: We present SCARPA, a novel scaffolder, which combines fixed-parameter tractable and bounded algorithms with Linear Programming to produce near-optimal... 
ASSEMBLER | SEQUENCE DATA | GENOMES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | Programming, Linear | Algorithms | Escherichia coli - genetics | Ascomycota - genetics | High-Throughput Nucleotide Sequencing | Software | Genomics - methods | Contig Mapping - methods | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2015, Volume 10, Issue 2, pp. e0113482 - e0113482
Objectives The extent and relevance of altered bone metabolism for statural growth in children with chronic kidney disease is controversial. We analyzed the... 
SCLEROSTIN | OSTEOCYTES | ALKALINE-PHOSPHATASE | MULTIDISCIPLINARY SCIENCES | SERUM-LEVELS | HEMODIALYSIS-PATIENTS | CONSEQUENCES | DISORDER | CLASSIFICATION | OSTEODYSTROPHY | FGF23 | Isoenzymes - blood | Humans | Tartrate-Resistant Acid Phosphatase | Male | Bone Morphogenetic Proteins - blood | Biomarkers - blood | Genetic Markers | Renal Insufficiency, Chronic - physiopathology | Kidney Function Tests | Renal Insufficiency, Chronic - blood | Fibroblast Growth Factors - blood | Bone and Bones - metabolism | Adolescent | Female | Human Growth Hormone - administration & dosage | Acid Phosphatase - blood | Child | Alkaline Phosphatase - blood | Pediatrics | Somatotropin | Phosphatases | C-reactive protein | Chronic kidney failure | Parathyroid hormone | Physiological aspects | Children | Comparative analysis | Health aspects | Diseases | Therapy | Fibroblast growth factor | Alkaline phosphatase | Nephrology | Renal function | Transplants & implants | Fibroblast growth factor 23 | SOST protein | Phosphatase | Peritoneal dialysis | Impact analysis | Consortia | Biomedical materials | Bone growth | Metabolites | Mineralization | Acid resistance | Fibroblasts | Biocompatibility | Standard deviation | Growth factors | Predictive control | Recombinant | Kidneys | Epidermal growth factor receptors | Markers | Endocrine therapy | Preventive medicine | Bone turnover | Metabolism | Glomerular filtration rate | Body height | Hospitals | Growth hormones | Acid phosphatase (tartrate-resistant) | Kidney diseases | Bone | University faculty | Growth hormone | Acid phosphatase | Endocrinology | Metabolic disorders | Index Medicus
Journal Article
Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques, ISSN 1895-4588, 06/2017, Volume 12, Issue 2, pp. 125 - 134
Pneumoperitoneum (PP) is known to cause ischemia in kidneys and other intra-abdominal organs because of decreased splanchnic blood flow. We aimed to determine... 
cystatin C | pneumoperitoneum | acute kidney injury | rats | neutrophil gelatinase-associated lipocalin
Journal Article
International Journal of Thermal Sciences, ISSN 1290-0729, 2007, Volume 46, Issue 12, pp. 1318 - 1322
Journal Article
Wideochirurgia I Inne Techniki Maloinwazyjne, ISSN 1895-4588, 06/2017, Volume 12, Issue 2, pp. 125 - 134
Journal Article
Journal Article
2011, Lecture Notes in Computer Science, ISBN 9783642200359, Volume 6577
As whole genome sequencing has become a routine biological experiment, algorithms for assembly of whole genome shotgun data has become a topic of extensive... 
Computational Biology/Bioinformatics | Computer Science | Database Management | Computation by Abstract Devices | Artificial Intelligence (incl. Robotics) | Computer Science, general | Algorithm Analysis and Problem Complexity | polymorphism | Genome assembly
Book Chapter
Cancer Cell, ISSN 1535-6108, 03/2019, Volume 35, Issue 3, pp. 414 - 427.e6
DNA sequencing has identified recurrent mutations that drive the aggressiveness of prostate cancers. Surprisingly, the influence of genomic, epigenomic, and... 
genome | prostate cancer | epigenome | transcriptome | multi-omic features | biomarker | proteome | HETEROGENEITY | MORTALITY | ONCOLOGY | PROTEOME | PACKAGE | QUANTIFICATION | ANNOTATION | RECURRENCE | MUTATIONS | IDENTIFICATION | EXPRESSION | CELL BIOLOGY | RNA | Prostate cancer | Analysis | Genomics
Journal Article
Cumhuriyet Medical Journal, ISSN 1305-0028, 12/2017, Volume 39, Issue 4, pp. 659 - 664
Journal Article
Genetics, ISSN 0016-6731, 02/2009, Volume 181, Issue 2, pp. 685 - 690
Journal Article
by Tarabichi, Maxime and Tarabichi, Maxime and Martincorena, Iñigo and Gerstung, Moritz and Gerstung, Moritz and Leroi, Armand M and Markowetz, Florian and Markowetz, Florian and Dentro, Stefan C and Leshchiner, Ignaty and Spellman, Paul T and Morris, Quaid D and Jolly, Clemency and Lingjærde, Ole Christian and Haase, Kerstin and Wedge, David C and Wintersinger, Jeff and Deshwar, Amit G and Van Loo, Peter and Yu, Kaixian and Gonzalez, Santiago and Rubanova, Yulia and Macintyre, Geoff and Adams, David J and Anur, Pavana and Beroukhim, Rameen and Boutros, Paul C and Bowtell, David D and Campbell, Peter J and Cao, Shaolong and Christie, Elizabeth L and Cmero, Marek and Cun, Yupeng and Dawson, Kevin J and Demeulemeester, Jonas and Donmez, Nilgun and Drews, Ruben M and Eils, Roland and Fan, Yu and Fittall, Matthew and Garsed, Dale W and Getz, Gad and Ha, Gavin and Imielinski, Marcin and Jerman, Lara and Ji, Yuan and Kleinheinz, Kortine and Lee, Juhee and Lee-Six, Henry and Livitz, Dimitri G and Malikic, Salem and Mitchell, Thomas J and Mustonen, Ville and Oesper, Layla and Peifer, Martin and Peto, Myron and Raphael, Benjamin J and Rosebrock, Daniel and Sahinalp, S. Cenk and Salcedo, Adriana and Schlesner, Matthias and Schumacher, Steven and Sengupta, Subhajit and Shi, Ruian and Shin, Seung Jun and Stein, Lincoln D and Vázquez-García, Ignacio and Vembu, Shankar and Wheeler, David A and Yang, Tsun-Po and Yao, Xiaotong and Yuan, Ke and Zhu, Hongtu and Wang, Wenyi and Morris, Quaid D and Spellman, Paul T and Wedge, David C and Van Loo, Peter and Lingjærde, Ole Christian and PCAWG Evolution Heterogeneity and PCAWG Evolution and Heterogeneity Working Group and The PCAWG Evolution and Heterogeneity Working Group
Nature Genetics, ISSN 1061-4036, 12/2018, Volume 50, Issue 12, pp. 1630 - 1633
According to this traditional model, the selective advantage is conferred by a small set of driver mutations, but as the subclones that bear them successively... 
PATTERNS | CLONAL EVOLUTION | CANCER | GENETICS & HEREDITY | Research | Neutral evolution | Oncology, Experimental | Cancer | Genetic drift | Medical research | Computer simulation | Neutrality | Genomes | Gene sequencing | Genetic variance | Simulation | Cell death | Frequency distribution | Drift | Mutation | Charitable foundations | Tumors | Apoptosis
Journal Article