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1. Full Text A reference map of potential determinants for the human serum metabolome
by Bar, Noam and Korem, Tal and Weissbrod, Omer and Zeevi, David and Rothschild, Daphna and Leviatan, Sigal and Kosower, Noa and Lotan-Pompan, Maya and Weinberger, Adina and Le Roy, Caroline I and Menni, Cristina and Visconti, Alessia and Falchi, Mario and Spector, Tim D and Vestergaard, Henrik and Arumugam, Manimozhiyan and Hansen, Torben and Allin, Kristine and Hansen, Tue and Hong, Mun-Gwan and Schwenk, Jochen and Haussler, Ragna and Dale, Matilda and Giorgino, Toni and Rodriquez, Marianne and Perry, Mandy and Nice, Rachel and McDonald, Timothy and Hattersley, Andrew and Jones, Angus and Graefe-Mody, Ulrike and Baum, Patrick and Grempler, Rolf and Thomas, Cecilia Engel and Masi, Federico De and Brorsson, Caroline Anna and Mazzoni, Gianluca and Allesøe, Rosa and Rasmussen, Simon and Gudmundsdóttir, Valborg and Nielsen, Agnes Martine and Banasik, Karina and Tsirigos, Konstantinos and Nilsson, Birgitte and Pedersen, Helle and Brunak, Søren and Karaderi, Tugce and Lundgaard, Agnete Troen and Johansen, Joachim and Gupta, Ramneek and Sackett, Peter Wad and Tillner, Joachim and Lehr, Thorsten and Scherer, Nina and Dings, Christiane and Sihinevich, Iryna and Loftus, Heather and Cabrelli, Louise and McEvoy, Donna and Mari, Andrea and Bizzotto, Roberto and Tura, Andrea and ’t Hart, Leen and Dekkers, Koen and Leeuwen, Nienke van and Slieker, Roderick and Rutters, Femke and Beulens, Joline and Nijpels, Giel and Koopman, Anitra and Oort, Sabine van and Groeneveld, Lenka and Groop, Leif and Elders, Petra and Viñuela, Ana and Ramisch, Anna and Dermitzakis, Emmanouil and Ehrhardt, Beate and Jennison, Christopher and Froguel, Philippe and Canouil, Mickaël and Boneford, Amélie and McVittie, Ian and Wake, Dianne and Frau, Francesca and Staerfeldt, Hans-Henrik and Adragni, Kofi and Thomas, Melissa and Wu, Han and Pavo, Imre and Steckel-Hamann, Birgit and Thomsen, Henrik and Giordano, Giuseppe Nicola and Fitipaldi, Hugo and Ridderstråle, Martin and Kurbasic, Azra and Pasdar, Naeimeh Atabaki and Pomares-Millan, Hugo and Mutie, Pascal and Koivula, Robert and ... and IMI DIRECT Consortium and IMI DIRECT consortium
Nature (London), ISSN 0028-0836, 12/2020, Volume 588, Issue 7836, pp. 135 - 140
General | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Statistical analysis | Microbiomes | Statistical methods | Bread | Learning algorithms | Algorithms | Diet | Metabolites | Machine learning | Biomarkers | Genetics | Determinants | Intestinal microflora | Index Medicus | Näringslära | Hälsovetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Nutrition and Dietetics | Health Sciences
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2. Full Text Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration
by Wilman, Henry R and Parisinos, Constantinos A and Atabaki-Pasdar, Naeimeh and Kelly, Matt and Thomas, E. Louise and Neubauer, Stefan and Jennison, Christopher and Ehrhardt, Beate and Baum, Patrick and Schoelsch, Corinna and Freijer, Jan and Grempler, Rolf and Graefe-Mody, Ulrike and Hennige, Anita and Dings, Christiane and Lehr, Thorsten and Scherer, Nina and Sihinecich, Iryna and Pattou, Francois and Raverdi, Violeta and Caiazzo, Robert and Torres, Fanelly and Verkindt, Helene and Mari, Andrea and Tura, Andrea and Giorgino, Toni and Bizzotto, Roberto and Froguel, Philippe and Bonneford, Amelie and Canouil, Mickael and Dhennin, Veronique and Brorsson, Caroline and Brunak, Soren and De Masi, Federico and Gudmundsdóttir, Valborg and Pedersen, Helle and Banasik, Karina and Thomas, Cecilia and Sackett, Peter and Staerfeldt, Hans-Henrik and Lundgaard, Agnete and Nilsson, Birgitte and Nielsen, Agnes and Mazzoni, Gianluca and Karaderi, Tugce and Rasmussen, Simon and Johansen, Joachim and Allesøe, Rosa and Fritsche, Andreas and Thorand, Barbara and Adamski, Jurek and Grallert, Harald and Haid, Mark and Sharma, Sapna and Troll, Martina and Adam, Jonathan and Ferrer, Jorge and Eriksen, Heather and Frost, Gary and Haussler, Ragna and Hong, Mun-gwan and Schwenk, Jochen and Uhlen, Mathias and Nicolay, Claudia and Pavo, Imre and Steckel-Hamann, Birgit and Thomas, Melissa and Adragni, Kofi and Wu, Han and Hart, Leen't and Roderick, Slieker and van Leeuwen, Nienke and Dekkers, Koen and Frau, Francesca and Gassenhuber, Johann and Jablonka, Bernd and Musholt, Petra and Ruetten, Hartmut and Tillner, Joachim and Baltauss, Tania and Bernard Poenaru, Oana and de Preville, Nathalie and Rodriquez, Marianne and Arumugam, Manimozhiyan and Allin, Kristine and Engelbrechtsen, Line and Hansen, Torben and Hansen, Tue and Forman, Annemette and Jonsson, Anna and Pedersen, Oluf and Dutta, Avirup and Vogt, Josef and Vestergaard, Henrik and Laakso, Markku and Kokkola, Tarja and Kuulasmaa, Teemu and Franks, Paul and Giordano, Nick and Pomares-Millan, Hugo and ... and IMI DIRECT Consortium
Journal of hepatology, ISSN 0168-8278, 09/2019, Volume 71, Issue 3, pp. 594 - 602
Genetics | Iron | Magnetic resonance imaging | Genome-wide association study | Metabolism | Metabolic syndrome | b_open_article_in_toll_access_journal | yes | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Humans | Liver - metabolism | Middle Aged | Magnetic Resonance Imaging - methods | Male | United Kingdom | Biomarkers - blood | Phenotype | Hemochromatosis Protein - genetics | Mendelian Randomization Analysis | Hepcidins - genetics | Adult | Female | Aged | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Hemochromatosis - genetics | Cohort Studies | Iron - blood | Hypertension | Obesity | Nuclear magnetic resonance--NMR | Liver diseases | Liver | Diabetes mellitus | Association analysis | Cardiovascular disease | Genomes | Coronary artery disease | Hip | Cirrhosis | Genetic variance | Blood pressure | Hepcidin | Heart diseases | Metabolic disorders | Index Medicus | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Gastroenterologi | Klinisk medicin | Gastroenterology and Hepatology
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3. Full Text Cellular Senescence as a Mechanism and Target in Chronic Lung Diseases
by Barnes, Peter J and Baker, Jonathan and Donnelly, Louise E
American journal of respiratory and critical care medicine, ISSN 1073-449X, 09/2019, Volume 200, Issue 5, pp. 556 - 564
Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Humans | Middle Aged | Oxidative Stress - physiology | Cellular Senescence - drug effects | Male | Pulmonary Disease, Chronic Obstructive - physiopathology | Cell Division - physiology | Epithelial Cells - physiology | Antioxidants - therapeutic use | Aged, 80 and over | Adult | Female | Aged | Idiopathic Pulmonary Fibrosis - physiopathology | Idiopathic Pulmonary Fibrosis - drug therapy | Pulmonary Disease, Chronic Obstructive - drug therapy | Oxidative stress | Senescence | DNA damage | Infections | Kinases | Autophagy | Cell cycle | Fibroblasts | Aging | Chronic obstructive pulmonary disease | Telomerase | Age | Deoxyribonucleic acid--DNA | Chronic illnesses | Hypertension | Mortality | Cyclin-dependent kinases | Lung diseases | Cell division | Cystic fibrosis | Pulmonary fibrosis | Lungs | Stem cells | Emphysema | Apoptosis | Index Medicus | Abridged Index Medicus
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4. Full Text Defective Phagocytosis in Airways Disease
by Donnelly, Louise E., PhD and Barnes, Peter J., DM, FCCP
Chest, ISSN 0012-3692, 2012, Volume 141, Issue 4, pp. 1055 - 1062
Pulmonary/Respiratory | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Cardiology. Vascular system | Biological and medical sciences | Medical sciences | Pneumology | Asthma - microbiology | Asthma - physiopathology | Pulmonary Disease, Chronic Obstructive - microbiology | Cystic Fibrosis - microbiology | Cystic Fibrosis - physiopathology | Humans | Phagocytosis - physiology | Respiratory Tract Diseases - physiopathology | Pulmonary Disease, Chronic Obstructive - physiopathology | Respiratory Tract Diseases - drug therapy | Respiratory Tract Diseases - microbiology | Physiological aspects | Health aspects | Lung diseases | Phagocytosis | Chest | Oxidative stress | Pathogens | Lung | Mortality | Homeostasis | Cystic fibrosis | Leukocytes (neutrophilic) | Macrophages | Cell surface | Sterility | Morbidity | Asthma | Antioxidants | Respiratory tract | Phagocytes | Monocytes | Respiratory tract diseases | Chronic obstructive pulmonary disease | Alveoli | Colonization | Apoptosis | Immune system | Index Medicus | Abridged Index Medicus
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5. Full Text Identification of a distinct glucocorticosteroid-insensitive pulmonary macrophage phenotype in patients with chronic obstructive pulmonary disease
by Chana, Kirandeep K., BSc, PhD and Fenwick, Peter S., BSc, MSc and Nicholson, Andrew G., MD and Barnes, Peter J., FRS, FMedSci and Donnelly, Louise E., PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2013, Volume 133, Issue 1, pp. 207 - 216.e11
Allergy and Immunology | CD206 | CD163 | flow cytometry | Matrix metalloproteinase 9 | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Immunopathology | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Biological and medical sciences | Medical sciences | Chronic obstructive pulmonary disease, asthma | Pneumology | Cell Separation | Humans | Middle Aged | Tumor Necrosis Factor-alpha - secretion | Immunophenotyping | Male | Antigens, CD - metabolism | Budesonide - pharmacology | Matrix Metalloproteinase 9 - metabolism | Flow Cytometry | Macrophages, Alveolar - drug effects | Budesonide - therapeutic use | Female | Interleukin-10 - secretion | Interleukin-8 - metabolism | Pulmonary Disease, Chronic Obstructive - immunology | Drug Resistance | Macrophages, Alveolar - immunology | Pulmonary Disease, Chronic Obstructive - drug therapy | Lung diseases, Obstructive | Care and treatment | Genetic aspects | Corticosteroids | Macrophages | Values | Genotype & phenotype | Chronic obstructive pulmonary disease | Methods | Smoking | Index Medicus | Abridged Index Medicus
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6. Full Text The lipidome: a new player in chronic obstructive pulmonary disease pathophysiology?
by Donnelly, Louise E and Donnelly, Louise E
American journal of respiratory and critical care medicine, ISSN 1073-449X, 2014, Volume 190, Issue 2, pp. 124 - 125
Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Smoking - metabolism | Humans | Female | Male | Sphingolipids - metabolism | Pulmonary Disease, Chronic Obstructive - metabolism | Sputum - metabolism | Index Medicus | Abridged Index Medicus
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7. Full Text New users of metformin are at low risk of incident cancer: A cohort study among people with type 2 diabetes
by Libby, Gillian and Donnelly, Louise A and Donnan, Peter T and Alessi, Dario R and Morris, Andrew D and Evans, Josie M. M
Diabetes care, ISSN 0149-5992, 09/2009, Volume 32, Issue 9, pp. 1620 - 1625
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Public health. Hygiene-occupational medicine | Public health. Hygiene | Diabetes. Impaired glucose tolerance | Miscellaneous | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Metabolic diseases | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Hypoglycemic Agents - therapeutic use | Metformin - therapeutic use | Humans | Middle Aged | Proportional Hazards Models | Male | Aged, 80 and over | Adult | Female | Aged | Diabetes Mellitus, Type 2 - drug therapy | Neoplasms - epidemiology | Cohort Studies | Prevention | Type 2 diabetes | Diabetics | Blood sugar | Oncology, Experimental | Research | Diabetes | Risk factors | Cancer | Mortality | Job classification | Breast cancer | Statistical methods | Regression analysis | Kinases | Cancer therapies | Prescription drugs | Cell growth | Hospitals | Databases | Stem cells | Health informatics | Index Medicus | Original Research
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