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Journal Article
Structure, ISSN 0969-2126, 09/2011, Volume 19, Issue 9, pp. 1283 - 1293
Methylxanthines, including caffeine and theophylline, are among the most widely consumed stimulant drugs in the world. These effects are mediated primarily via... 
Journal Article
Science, ISSN 0036-8075, 05/2019, Volume 364, Issue 6442, p. 775
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2012, Volume 55, Issue 5, pp. 1898 - 1903
Journal Article
Structure, ISSN 0969-2126, 08/2017, Volume 25, Issue 8, pp. 1275 - 1285.e4
The adenosine A and A receptors belong to the purinergic family of G protein-coupled receptors, and regulate diverse functions of the cardiovascular,... 
caffeine | PSB36 | xanthine | theophylline | adenosine A1 receptor structure | adenosine A2A receptor structure
Journal Article
Journal Article
Nature, ISSN 0028-0836, 04/2016, Volume 533, Issue 7602, pp. 274 - 277
Journal Article
Journal Article
Journal Article
Nature, ISSN 0028-0836, 05/2017, Volume 545, Issue 7652, pp. 112 - 115
Protease-activated receptors ( PARs) are a family of G-proteincoupled receptors ( GPCRs) that are irreversibly activated by proteolytic cleavage of the N... 
PHENIX | THROMBIN | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | Allosteric Regulation - drug effects | Benzyl Alcohols - chemistry | Allosteric Site - drug effects | Humans | Receptor, PAR-2 - metabolism | Imidazoles - chemistry | Models, Molecular | Crystallography, X-Ray | Antibodies, Blocking - pharmacology | Imidazoles - pharmacology | Benzimidazoles - chemistry | Receptor, PAR-2 - chemistry | Immunoglobulin Fab Fragments - pharmacology | Receptor, PAR-2 - antagonists & inhibitors | Signal Transduction - drug effects | Antibodies, Blocking - chemistry | Immunoglobulin Fab Fragments - chemistry | Benzyl Alcohols - pharmacology | Benzimidazoles - pharmacology | Ligands | Benzodioxoles - chemistry | Kinetics | Benzodioxoles - pharmacology | Physiological aspects | Cell receptors | Allosteric proteins | Cytochrome | Residues | G protein-coupled receptors | Peptides | Molecular structure | Hydrogen | Homology | Antagonists | Hydrophobicity | Hydrogen bonding | Optimization | Proteins | Lipophilic | Allosteric properties | Imidazole | Cleavage | Inhibition | Thromboembolism | Lysozyme | Hydrogen ion concentration | Deoxyribonucleic acid--DNA | Cultivation | Architecture | Fab | Crystals | Crystallization | Pharmacology | Inflammation | Glycosylation | Computer programs | Chemistry | Diffraction | Antagonist drugs | Lysine | Isoforms | Computer applications | Mutation | Internet | Receptor mechanisms | Binding sites | Glutamine | Cancer
Journal Article