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Nature (London), ISSN 0028-0836, 09/2016, Volume 538, Issue 7625, pp. 344 - 349
...]; Nicolas M. Brancucci [2]; Joshua A. Bittker [1]; Victoria Corey [5]; David Clarke [2]; Emily R. Derbyshire [1, 6, 7]; Gillian L. Dornan [8]; Sandra Duffy [9]; Sean... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Azabicyclo Compounds - pharmacology | Plasmodium falciparum - enzymology | Malaria, Falciparum - prevention & control | Male | Plasmodium falciparum - cytology | Azetidines - pharmacology | Plasmodium falciparum - drug effects | Cytosol - enzymology | Malaria, Falciparum - transmission | Liver - drug effects | Azabicyclo Compounds - chemical synthesis | Azabicyclo Compounds - therapeutic use | Female | Safety | Antimalarials - chemical synthesis | Disease Models, Animal | Life Cycle Stages - drug effects | Malaria, Falciparum - drug therapy | Azabicyclo Compounds - administration & dosage | Azetidines - adverse effects | Phenylurea Compounds - therapeutic use | Antimalarials - therapeutic use | Macaca mulatta - parasitology | Phenylalanine-tRNA Ligase - antagonists & inhibitors | Drug Discovery | Antimalarials - pharmacology | Animals | Azetidines - administration & dosage | Phenylurea Compounds - chemical synthesis | Antimalarials - administration & dosage | Azetidines - therapeutic use | Phenylurea Compounds - administration & dosage | Mice | Phenylurea Compounds - pharmacology | Liver - parasitology | Plasmodium falciparum - growth & development | Prevention | Antimalarials | Disease transmission | Health aspects | Transfer RNA | Proteins | Cytochrome | Malaria | Liver | Parasites | Kinases | Drug resistance | Drug dosages | Index Medicus
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 10/2017, Volume 140, Issue 4, pp. 1152 - 1156.e10
Supporting an intramolecular activation mechanism, we found no difference in association of ectopically expressed WT, E81K, or G124D p110δ with endogenous p85α... 
Allergy and Immunology | Pneumonia | Senescence | Endometrial cancer | Lymphocytes | Leukemia | Ear diseases | Amino acids | Mutation | Kinases | Patients | Age | Index Medicus | Abridged Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 02/2017, Volume 114, Issue 8, pp. 1982 - 1987
Activated PI3K Delta Syndrome (APDS) is a primary immunodeficiency disease caused by activating mutations in either the leukocyte-restricted p110δ catalytic (... 
PIK3CD | Phosphoinositides | PIK3R1 | HDX-MS | PI3K/AKT | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Index Medicus | Biological Sciences | PI3K | AKT | phosphoinositides
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 11/2017, Volume 358, Issue 6366, pp. 1056 - 1059
Journal Article
Frontiers in immunology, ISSN 1664-3224, 03/2018, Volume 9, pp. 575 - 575
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 02/2017, Volume 114, Issue 8, p. 1982
Activated PI3K Delta Syndrome (APDS) is a primary immunodeficiency disease caused by activating mutations in either the leukocyte-restricted p110δ catalytic... 
Leucocytes | Biochemistry | Mutation | Biological assays | Mass spectrometry | Medical disorders
Journal Article
Frontiers in immunology, ISSN 1664-3224, 2018, Volume 9, p. 575
The signaling lipid phosphatidylinositol 3,4,5, trisphosphate (PIP ) is an essential mediator of many vital cellular processes, including growth, survival, and... 
Journal Article
Journal of molecular biology, ISSN 0022-2836, 09/2018, Volume 430, Issue 18, pp. 3129 - 3142
Phosphatidylinositol 4-kinase IIIα (PI4KIIIα) is the lipid kinase primarily responsible for generating the lipid phosphatidylinositol 4-phosphate (PI4P) at the... 
PI4KA | FAM126 | TTC7 | HDX-MS | phosphatidylinositol 4-kinase | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology
Journal Article