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insulin resistance (10) 10
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vascular smooth muscle cells (9) 9
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cells, cultured (7) 7
muscle, smooth, vascular - drug effects (7) 7
nitric oxide - metabolism (7) 7
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peripheral vascular disease (6) 6
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obesity (5) 5
phosphoproteins - metabolism (5) 5
phosphorylation (5) 5
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signal transduction (5) 5
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insulin (4) 4
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mitogen-activated protein kinase (4) 4
muscle, smooth, vascular - enzymology (4) 4
myocytes, smooth muscle - enzymology (4) 4
phosphatidylinositol 3-kinase (4) 4
phosphatidylinositol 3-kinases - metabolism (4) 4
platelet aggregation inhibitors - pharmacology (4) 4
platelets (4) 4
rats (4) 4
rats, zucker (4) 4
signal transduction - drug effects (4) 4
time factors (4) 4
vascular endothelial growth factor (4) 4
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cgmp (3) 3
cyclic amp - metabolism (3) 3
dose-response relationship, drug (3) 3
endothelial cells (3) 3
endothelial growth-factor (3) 3
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insulin - pharmacology (3) 3
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matrix metalloproteinase 2 - biosynthesis (3) 3
medical laboratory technology (3) 3
metabolic syndrome (3) 3
mitogen-activated protein kinases - metabolism (3) 3
mitogens (3) 3
muscle, smooth, vascular - cytology (3) 3
myocytes, smooth muscle - drug effects (3) 3
nadph oxidases - metabolism (3) 3
obesity - metabolism (3) 3
oxidative stress (3) 3
phosphorylation - drug effects (3) 3
platelet aggregation (3) 3
protein biosynthesis (3) 3
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zucker rats (3) 3
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aggregation (2) 2
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Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 1015 - 1015
Journal Article
Diabetes, ISSN 0012-1797, 11/2012, Volume 61, Issue 11, pp. 2913 - 2921
Since hyperglycemia is involved in the "aspirin resistance" occurring in diabetes, we aimed at evaluating whether high glucose interferes with the... 
OXIDE SYNTHASE | IN-VITRO | OBESITY | HYPERGLYCEMIA | CARDIOVASCULAR EVENTS | PHOSPHORYLATION | ENDOCRINOLOGY & METABOLISM | RESISTANCE | SENSITIVITY | STRESS | AGGREGATION | Amifostine - pharmacology | Humans | Male | Blood Platelets - enzymology | Phosphoproteins - metabolism | Cyclic GMP-Dependent Protein Kinases - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Young Adult | Cyclic GMP-Dependent Protein Kinases - antagonists & inhibitors | Protein Processing, Post-Translational - drug effects | Thromboxanes - metabolism | Platelet Aggregation Inhibitors - pharmacology | Adult | Female | Microfilament Proteins - metabolism | Aspirin - pharmacology | Phosphorylation - drug effects | Blood Platelets - drug effects | Drug Resistance | Lysine - analogs & derivatives | Second Messenger Systems - drug effects | Vasodilator Agents - pharmacology | Nitric Oxide - antagonists & inhibitors | Cell Adhesion Molecules - metabolism | Hyperglycemia - metabolism | Lysine - pharmacology | Cyclic GMP - metabolism | Hyperglycemia - blood | Aspirin - analogs & derivatives | Blood Platelets - metabolism | Hyperglycemia - enzymology | Nitric Oxide - metabolism | Cyclic GMP - antagonists & inhibitors | Measurement | Blood platelets | Blood sugar | Analysis | Physiological aspects | Research | Protein kinases | Index Medicus | Abridged Index Medicus | Pathophysiology
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 2012, Volume 13, Issue 8, pp. 9478 - 9488
Journal Article
by Nanda, Vashisht G. Y and Peng, Weiyi and Hwu, Patrick and Davies, Michael A and Ciliberto, Gennaro and Fattore, Luigi and Malpicci, Debora and Aurisicchio, Luigi and Ascierto, Paolo Antonio and Croce, Carlo M and Mancini, Rita and Spranger, Stefani and Gajewski, Thomas F and Wang, Yangyang and Ferrone, Soldano and Vanpouille-Box, Claire and Wennerberg, Erik and Pilones, Karsten A and Formenti, Silvia C and Demaria, Sandra and Tang, Haidong and Wang, Yang and Fu, Yang-Xin and Dummer, Reinhard and Puzanov, Igor and Tarhini, Ahmad and Chauvin, Joe-Marc and Pagliano, Ornella and Fourcade, Julien and Sun, Zhaojun and Wang, Hong and Sanders, Cindy and Kirkwood, John M and Chen, Tseng-hui Timothy and Maurer, Mark and Korman, Alan J and Zarour, Hassane M and Stroncek, David F and Huber, Veronica and Rivoltini, Licia and Thurin, Magdalena and Rau, Tilman and Lugli, Alessandro and Pagès, Franck and Camarero, Jorge and Sancho, Arantxa and Jommi, Claudio and de Coaña, Yago Pico and Wolodarski, Maria and Yoshimoto, Yuya and Gentilcore, Giusy and Poschke, Isabel and Masucci, Giuseppe V and Hansson, Johan and Kiessling, Rolf and Scognamiglio, Giosuè and Sabbatino, Francesco and Marino, Federica Zito and Anniciello, Anna Maria and Cantile, Monica and Cerrone, Margherita and Scala, Stefania and D’alterio, Crescenzo and Ianaro, Angela and Cirin, Giuseppe and Liguori, Giuseppina and Bott, Gerardo and Chapman, Paul B and Robert, Caroline and Larkin, James and Haanen, John B and Ribas, Antoni and Hogg, David and Hamid, Omid and Testori, Alessandro and Lorigan, Paul and Sosman, Jeffrey A and Flaherty, Keith T and Yue, Huibin and Coleman, Shelley and Caro, Ivor and Hauschild, Axel and McArthur, Grant A and Sznol, Mario and Callahan, Margaret K and Kluger, Harriet and Postow, Michael A and Gordan, RuthAnn and Segal, Neil H and Rizvi, Naiyer A and Lesokhin, Alexander and Atkins, Michael B and Burke, Matthew M and Ralabate, Amanda and Rivera, Angel and Kronenberg, Stephanie A and Agunwamba, Blessing and Ruisi, Mary and Horak, Christine and Jiang, Joel and ...
Journal of translational medicine, ISSN 1479-5876, 07/2016, Volume 14, Issue 1, pp. 65 - 65
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 09/2013, Volume 14, Issue 9, pp. 18861 - 18880
Obesity is characterized by poor collateral vessel formation, a process involving vascular endothelial growth factor (VEGF) action on vascular smooth muscle... 
Mitogen activated protein kinase | Obesity | Oxidative stress | Protein kinase C | Oleic acid | Phosphatidylinositol 3-kinase | Zucker rats | Vascular endothelial growth factor | Vascular smooth muscle cells | FATTY ZUCKER RAT | oleic acid | mitogen activated protein kinase | CORONARY COLLATERAL GROWTH | ANGIOTENSIN-II | MECHANISMS | CHEMISTRY, MULTIDISCIPLINARY | ABDOMINAL OBESITY | SIGNALING PATHWAY | vascular endothelial growth factor | INSULIN-RESISTANCE | INFLAMMATION | CARDIOVASCULAR-DISEASE | vascular smooth muscle cells | EXPRESSION | obesity | oxidative stress | protein kinase C | phosphatidylinositol 3-kinase | Reactive Oxygen Species - metabolism | Muscle, Smooth, Vascular - metabolism | TOR Serine-Threonine Kinases - metabolism | NADPH Oxidases - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Vascular Endothelial Growth Factor A - metabolism | RNA, Messenger - metabolism | Vascular Endothelial Growth Factor A - genetics | Mitogen-Activated Protein Kinase Kinases - metabolism | Oleic Acid - pharmacology | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Muscle, Smooth, Vascular - drug effects | Cells, Cultured | Hydrogen Peroxide - pharmacology | Rats | Muscle, Smooth, Vascular - cytology | Obesity - metabolism | Obesity - pathology | Rats, Zucker | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Signal Transduction - drug effects | Protein Kinase C beta - metabolism | Oxidative Stress - drug effects | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus
Journal Article
BioMed Research International, ISSN 2314-6133, 2014, Volume 2014, pp. 328959 - 9
Journal Article
Atherosclerosis, ISSN 0021-9150, 2011, Volume 216, Issue 1, pp. 44 - 53
Abstract Objective Vascular smooth muscle cells (VSMCs) from the animal model of insulin resistance obese Zucker rats (OZR) show impaired ability of nitric... 
Cardiovascular | PI3-K | Oxidative stress | Nitric oxide | cGMP | Insulin resistance | MAPK | Zucker rats | PKG | Vascular smooth muscle cells | CGMP | MICROVASCULAR DYSFUNCTION | APOPTOSIS | METABOLIC SYNDROME | CARDIOMYOCYTES | CYCLIC-GMP | INFLAMMATION | PROTEIN-KINASE PATHWAYS | PERIPHERAL VASCULAR DISEASE | PERFUSION | OBESE ZUCKER RAT | ENDOTHELIAL GROWTH-FACTOR | Oxidants - pharmacology | Phosphorylation | Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Humans | NADPH Oxidases - metabolism | JNK Mitogen-Activated Protein Kinases - metabolism | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Cyclic GMP-Dependent Protein Kinases - metabolism | Time Factors | Superoxides - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Nitric Oxide Donors - pharmacology | Myocytes, Smooth Muscle - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Phosphatidylinositol 3-Kinase - metabolism | Superoxide Dismutase - metabolism | Muscle, Smooth, Vascular - drug effects | Xanthine Oxidase - metabolism | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Myocytes, Smooth Muscle - enzymology | Insulin Resistance | Rats | Antioxidants - pharmacology | Blotting, Western | Rats, Zucker | Animals | Analysis of Variance | Cyclic GMP - metabolism | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Signal Transduction - drug effects | Electron Transport Chain Complex Proteins - metabolism | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Oxidative Stress - drug effects | Nitric Oxide - metabolism | Muscle, Smooth, Vascular - enzymology | Mitogen-Activated Protein Kinases - metabolism | Atherosclerosis | Index Medicus
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 2005, Volume 93, Issue 12, pp. 1285 - 1293
Summary In this study we aimed to test the hypothesis that in human vascular smooth muscle cells (VSMC) homocysteine influences synthesis and release of matrix... 
Cell Signalling and Vessel Remodelling | Matrix metalloproteinases | Phosphatidylinositol 3-kinase | Homocysteine | Mitogen-Activated Protein Kinase | Vascular smooth muscle cells
Journal Article
Journal Article
Journal Article
Angiogenesis, ISSN 0969-6970, 12/2012, Volume 15, Issue 4, pp. 713 - 725
Innate immunity may activate paracrine circuits able to entail vascular system in the onset and progression of several chronic degenerative diseases. In... 
Cell proliferation | Angiogenesis | Signal transduction | Biomedicine | Cytokines | Oncology | Cancer Research | Ophthalmology | Cardiology | T cells | Biomedicine general | Cell Biology
Journal Article
Angiogenesis, ISSN 0969-6970, 12/2012, Volume 15, Issue 4, p. 713
  Innate immunity may activate paracrine circuits able to entail vascular system in the onset and progression of several chronic degenerative diseases. In... 
Journal Article