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Journal of Clinical Oncology, ISSN 0732-183X, 03/2019, Volume 37, Issue 8_suppl, pp. TPS129 - TPS129
TPS129 Background: Preclinical studies indicate Receptor Activator of NF-κB Ligand (RANKL) blockade improves anti-tumor efficacy of immune checkpoint blockade... 
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2018, Volume 36, Issue 15_suppl, pp. e21001 - e21001
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 3320 - 3320
Journal Article
Nature, ISSN 0028-0836, 11/2010, Volume 468, Issue 7320, pp. 103 - 107
RANK ligand (RANKL), a TNF-related molecule, is essential for osteoclast formation, function and survival through interaction with its receptor RANK(1,2).... 
CELL FUNCTION | OSTEOPROTEGERIN-LIGAND | MULTIDISCIPLINARY SCIENCES | MEDROXYPROGESTERONE ACETATE | RECEPTOR | HORMONE REPLACEMENT THERAPY | HUMAN BREAST-TUMORS | OSTEOCLAST DIFFERENTIATION | EXPRESSION | GLAND DEVELOPMENT | TRANSGENIC MICE | Epithelial Cells - metabolism | RANK Ligand - metabolism | Progesterone - administration & dosage | Epithelial Cells - drug effects | Humans | Progestins - adverse effects | Cell Transformation, Neoplastic - chemically induced | Mammary Neoplasms, Experimental - metabolism | Mammary Neoplasms, Experimental - genetics | Breast Neoplasms - metabolism | Lung Neoplasms - secondary | Mammary Neoplasms, Experimental - pathology | Medroxyprogesterone Acetate - adverse effects | Female | Precancerous Conditions - pathology | Receptor Activator of Nuclear Factor-kappa B - metabolism | Disease Models, Animal | 9,10-Dimethyl-1,2-benzanthracene - administration & dosage | Neoplasm Invasiveness | Mice, Inbred C57BL | Epithelial Cells - pathology | Mice, Transgenic | Progesterone - adverse effects | Mammary Neoplasms, Experimental - chemically induced | RANK Ligand - genetics | Animals | RANK Ligand - antagonists & inhibitors | Breast Neoplasms - pathology | Progestins - administration & dosage | Receptor Activator of Nuclear Factor-kappa B - genetics | Cell Proliferation - drug effects | Medroxyprogesterone Acetate - administration & dosage | Mice | Cell Transformation, Neoplastic - drug effects | Precancerous Conditions - prevention & control | Cell Transformation, Neoplastic - pathology | Mammary Tumor Virus, Mouse - genetics | Mammary Tumor Virus, Mouse - physiology | 9,10-Dimethyl-1,2-benzanthracene - adverse effects | Immunohistochemistry | Care and treatment | Usage | Physiological aspects | Breast cancer | Genetic aspects | Research | Progesterone | Tumor proteins | Health aspects | Risk factors | Proteins | Hormone replacement therapy | Rodents | Apoptosis | Index Medicus
Journal Article
Clinical & Translational Immunology, ISSN 2050-0068, 2019, Volume 8, Issue 10, p. n/a
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2016, Volume 22, Issue 8, pp. 933 - 939
Individuals who have mutations in the breast-cancer-susceptibility gene BRCA1 (hereafter referred to as BRCA1-mutation carriers) frequently undergo... 
BRCA2 MUTATION CARRIERS | MEDICINE, RESEARCH & EXPERIMENTAL | TUMOR-DEVELOPMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | OVARIAN-CANCER | CELL BIOLOGY | RISK-REDUCING SURGERY | STEM-CELL | MICE | DIFFERENTIAL EXPRESSION ANALYSIS | GLAND | MAMMARY EPITHELIAL-CELLS | Immunohistochemistry | Neoplasm Transplantation | RANK Ligand - metabolism | Humans | Molecular Targeted Therapy | Prophylactic Mastectomy | Stem Cells - metabolism | Breast - metabolism | Breast Neoplasms - metabolism | Denosumab - therapeutic use | Flow Cytometry | Organoids - metabolism | Female | Receptor Activator of Nuclear Factor-kappa B - metabolism | Disease Models, Animal | Carcinogenesis - genetics | Bone Density Conservation Agents - therapeutic use | Reverse Transcriptase Polymerase Chain Reaction | Bone Density Conservation Agents - pharmacology | Breast Neoplasms - prevention & control | Carcinogenesis - drug effects | Xenograft Model Antitumor Assays | BRCA1 Protein - genetics | Animals | Breast Neoplasms - genetics | RANK Ligand - antagonists & inhibitors | Breast - drug effects | DNA Repair | Organoids - drug effects | Pilocarpine - analogs & derivatives | Stem Cells - drug effects | Heterozygote | Cell Proliferation - drug effects | Mice | Mutation | Denosumab - pharmacology | Tumor Suppressor Proteins | Care and treatment | Cytokines | BRCA mutations | Development and progression | Breast cancer | Genetic aspects | Health aspects | Ligands | Genes
Journal Article