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Philosophical Transactions of the Royal Society B: Biological Sciences, ISSN 0962-8436, 12/2005, Volume 360, Issue 1464, pp. 2355 - 2372
Journal Article
Advances in Experimental Medicine and Biology, ISSN 0065-2598, 2003, Volume 543, pp. 191 - 200
Free radical-derived reactive oxygen species (ROS) are constantly generated in most living tissue and can potentially damage DNA, proteins and lipids.... 
Thiol/disulfide redox status | Reactive oxygen species (ROS) | Redox regulation | Glutathione | Sulfhydryl Compounds - metabolism | Animals | Reactive Oxygen Species - metabolism | Aging - genetics | Oxidation-Reduction | Oxidative Stress | Signal Transduction | Humans | Longevity - genetics | Longevity - physiology | Aging - metabolism
Journal Article
Nature Cell Biology, ISSN 1465-7392, 01/2002, Volume 4, Issue 1, pp. 1 - 10
Transcriptional activity of p53, a central regulatory switch in a network controlling cell proliferation and apoptosis, is modulated by protein stability and... 
TRANSCRIPTION FACTORS | NUCLEAR-BODIES | PREMATURE SENESCENCE | PROMYELOCYTIC LEUKEMIA | DNA-DAMAGE | TUMOR-SUPPRESSOR | POTENTIAL MEDIATOR | CREB BINDING-PROTEIN | SERINE/THREONINE KINASE | P53-REGULATED GENE-EXPRESSION | CELL BIOLOGY | Apoptosis - radiation effects | Humans | Transcriptional Activation | Apoptosis - genetics | Neoplasm Proteins - metabolism | Tumor Suppressor Protein p53 - genetics | Carrier Proteins - radiation effects | Cell Nucleus - metabolism | Protein Isoforms - metabolism | Ultraviolet Rays | Protein-Serine-Threonine Kinases - radiation effects | Trans-Activators - genetics | Tumor Cells, Cultured | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Genes, Tumor Suppressor | Protein-Serine-Threonine Kinases - metabolism | Cell Division - genetics | Oligonucleotides, Antisense | CREB-Binding Protein | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | Nuclear Proteins - metabolism | Transcription Factors - genetics | Cell Nucleus - ultrastructure | Enzyme Activation - radiation effects | Transcription Factors - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Cell Nucleus - genetics | Protein Binding | Trans-Activators - metabolism | Mice | Promyelocytic Leukemia Protein | Tumor Suppressor Proteins | Protein Isoforms - genetics | Post-translational modification | Physiological aspects | Research | Tumor proteins | Protein kinases | Protein-protein interactions
Journal Article
by Klionsky, Daniel J and Abeliovich, Hagai and Agostinis, Patrizia and Agrawal, Devendra K and Aliev, Gjumrakch and Askew, David S and Baba, Misuzu and Baehrecke, Eric H and Bahr, Ben A and Ballabio, Andrea and Bamber, Bruce A and Bassham, Diane C and Bergamini, Ettore and Bi, Xiaoning and Biard-Piechaczyk, Martine and Blum, Janice S and Bredesen, Dale E and Brodsky, Jeffrey L and Brumell, John H and Brunk, Ulf T and Bursch, Wilfried and Camougrand, Nadine and Cebollero, Eduardo and Cecconi, Francesco and Chen, Yingyu and Chin, Lih-Shen and Choi, Augustine and Chu, Charleen T and Chung, Jongkyeong and Clark, Robert S.B and Clarke, Peter G.H and Clarke, Steven G and Clave, Corinne and Cleveland, John L and Codogno, Patrice and Colombo, María Isabel and Coto-Montes, Ana and Cregg, James M and Cuervo, Ana Maria and Debnath, Jayanta and Dennis, Patrick B and Dennis, Phillip A and Demarchi, Francesca and Deretic, Vojo and Devenish, Rodney J and Di Sano, Federica and Dice, J. Fred and Distelhorst, Clark W and Dinesh-Kumar, Savithramma P and Eissa, N. Tony and DiFiglia, Marian and Djavaheri-Mergny, Mojgan and Dorsey, Frank C and Dröge, Wulf and Dron, Michel and Dunn, Jr, William A and Duszenko, Michael and Elazar, Zvulun and Esclatine, Audrey and Eskelinen, Eeva-Liisa and Fésüs, László and Finley, Kim D and Fuentes, José M and Fueyo-Margareto, Juan and Fujisaki, Kozo and Galliot, Brigitte and Gao, Fen-Biao and Gewirtz, David A and Gibson, Spencer B and Gohla, Antje and Goldberg, Alfred L and Gonzalez, Ramon and González-Estévez, Cristina and Gorski, Sharon M and Gottlieb, Roberta A and Häussinger, Dieter and He, You-Wen and Heidenreich, Kim and Hill, Joseph A and Høyer-Hansen, Maria and Hu, Xun and Huang, Wei-Pang and Iwasaki, Akiko and Jäättelä, Marja and Jackson, William T and Jiang, Xuejun and Jin, Shengkan V and Johansen, Terje and Jung, Jae U and Kadowaki, Motoni and Kang, Chanhee and Kelekar, Ameeta and Kessel, David H and Kiel, Jan A.K.W and Kim, Hong Pyo and Kimchi, Adi and Kinsella, Timothy J and Kiselyov, Kirill and Kitamoto, Katsuhiko and Knecht, Erwin and ... and Geriatrik and Institutionen för medicin och hälsa and Farmakologi and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Hälsouniversitetet
Autophagy, ISSN 1554-8627, 02/2008, Volume 4, Issue 2, pp. 151 - 175
Journal Article
Autophagy, ISSN 1554-8627, 10/2005, Volume 1, Issue 3, pp. 131 - 140
A decrease in the rate of protein turnover and the intracellular accumulation of altered proteins in cytosol and membranes are features common to all aged... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | inummosenescence | RAT-LIVER | LIFE-SPAN | replicative senescence | OXIDATIVE-STRESS |