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1. Abstracts of papers, scientific exhibits and motion pictures [presented at the] 4th International Congress of Neurological Surgery [and] 9th International Congress of Neurology, Sep. 20-27, 1969, New York, N.Y. Editors
: Charles G. Drake [and] Roger Dovoisin
by Dovoisin, Roger and Drake, Charles G and International Neurological Congress. 9th, New York, 1969 and International Congress of Neurological Surgery. 4th, New York, 1969
1969, Excerpta Medica International Congress series, Volume no. 193, 317
Neurology | Congresses | Surgery | Nervous system
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2. Full Text Phenotypic analysis of prostate-infiltrating lymphocytes reveals T H17 and Treg skewing
by Sfanos, Karen Sandell and Bruno, Tullia C and Maris, Charles H and Xu, Lauren and Thoburn, Christopher J and Demarzo, Angelo M and Meeker, Alan K and Isaacs, William B and Drake, Charles G
Clinical Cancer Research, ISSN 1078-0432, 06/2008, Volume 14, Issue 11, pp. 3254 - 3261
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3. LAG-3 in cancer immunotherapy
by Goldberg, Monica V and Drake, Charles G
Current Topics in Microbiology and Immunology, ISSN 0070-217X, 2010, Volume 344, Issue 1, pp. 269 - 278
Checkpoint | Anergy | LAG-3 | Treg | Tumor immunology | Tolerance | CD8 lymphocyte | CD4 lymphocyte
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4. Surgery of vertebrobasilar aneurysms
: London, Ontario, experience on 1,767 patients
by Drake, Charles G and Peerless, S. J and Hernesniemi, J
1996, ISBN 3211826963, xvi, 329
Cerebral Aneurysm | physiopathology | Vertebrobasilar aneurysms | Vertebral Artery | Basilar Artery | Surgery
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5. Full Text Prostate cancer as a model for tumour immunotherapy
by Drake, Charles G
Nature Reviews Immunology, ISSN 1474-1733, 08/2010, Volume 10, Issue 8, pp. 580 - 593
Advances in basic immunology have led to an improved understanding of the interactions between the immune system and tumours, generating renewed interest in... 
ANDROGEN-DEPRIVATION THERAPY | IMMUNE-RESPONSE | METASTATIC MELANOMA | T-CELL RESPONSES | SOLID TUMORS | PHASE-I TRIAL | GM-CSF | COMBINATION THERAPY | ANTIGEN-PRESENTING CELLS | ANTITUMOR IMMUNITY | IMMUNOLOGY | Cancer Vaccines - therapeutic use | Animals | Humans | Male | Antineoplastic Agents - therapeutic use | Clinical Trials as Topic | Tissue Extracts - therapeutic use | Disease Models, Animal | Prostatic Neoplasms - immunology | Prostatic Neoplasms - therapy | Care and treatment | Research | Health aspects | Prostate cancer | Immunotherapy
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6. Endovascular treatment of intracranial aneurysms
by Byrne, J. V. 1950- (James V.) and Guglielmi, G. 1948- (Guido)
1998, ISBN 9783540627647, ix, 248
Intracranial aneurysms | Endoscopic surgery | therapy | methods | Cerebral Aneurysm | diagnosis | Embolization, Therapeutic
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7. Full Text The immunobiology of kidney cancer
by Drake, Charles G and Stein, Mark N
Journal of Clinical Oncology, ISSN 0732-183X, 12/2018, Volume 36, Issue 36, pp. 3547 - 3552
Although kidney cancer (renal cell carcinoma [RCC]) is susceptible to immunotherapy, the immunologic aspects of the tumor microenvironment (TME) in RCC are... 
ACTIVATION | THERAPY | ONCOLOGY | INFLAMMATION | REGULATORY T-CELLS | OPEN-LABEL | TUMOR VASCULATURE | COMBINATION | BLOCKADE | RENAL-CELL CARCINOMA | IL-10
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8. Full Text Efficacy of alpha-1,3-galactosyltransferase-expressing allogeneic renal cell carcinoma immunotherapy in patients (pts) with refractory metastatic renal cell carcinoma (mRCC)
by Hahn, Andrew W and Drake, Charles G and Denmeade, Samuel R and Zakharia, Yousef and Maughan, Benjamin Louis and Kennedy, Eugene Paul and Link, Charles J and Vahanian, Nicholas N and Hammers, Hans J and Agarwal, Neeraj
Journal of Clinical Oncology, ISSN 0732-183X, 03/2019, Volume 37, Issue 7_suppl, pp. 590 - 590
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9. Full Text Human prostate cancer immune phenotypes after androgen deprivation therapy
by Dallos, Matthew and Obradovic, Aleksandar and Chowdhury, Nivi and Lopez Bujanda, Zoila and Aggen, David Henry and Hawley, Jessica and Rathkopf, Dana E and Drake, Charles G
Journal of Clinical Oncology, ISSN 0732-183X, 05/2019, Volume 37, Issue 15_suppl, pp. 5083 - 5083
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10. Full Text Abstract IA15: Role of PD-1 and LAG-3 in cancer immunotherapy
by Drake, Charles G
Cancer Research, ISSN 0008-5472, 01/2013, Volume 73, Issue 1 Supplement, pp. IA15 - IA15
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11. Full Text Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy
by Topalian, Suzanne L and Drake, Charles G and Pardoll, Drew M
Cancer Cell, ISSN 1535-6108, 04/2015, Volume 27, Issue 4, pp. 450 - 461
The immune system recognizes and is poised to eliminate cancer but is held in check by inhibitory receptors and ligands. These immune checkpoint pathways,... 
METASTATIC MELANOMA | CTLA-4 BLOCKADE | SOLID TUMORS | ONCOLOGY | T-CELL-ACTIVATION | EFFECTOR FUNCTION | DOUBLE-BLIND | COSTIMULATORY MOLECULE | ANTITUMOR IMMUNITY | RESISTANT PROSTATE-CANCER | CHRONIC VIRAL-INFECTION | CELL BIOLOGY | CD28 Antigens - physiology | Antibodies, Monoclonal - pharmacology | Humans | Antibodies, Monoclonal - therapeutic use | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | CD28 Antigens - immunology | Programmed Cell Death 1 Receptor - physiology | CTLA-4 Antigen - immunology | Models, Immunological | Neoplasms - immunology | Immunotherapy | CD28 Antigens - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Programmed Cell Death 1 Receptor - immunology | CTLA-4 Antigen - antagonists & inhibitors | CTLA-4 Antigen - physiology | Antimitotic agents | Care and treatment | Antineoplastic agents | Health aspects | Cancer
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12. Full Text A phase 1 study of alpha-1,3-galactosyltransferase-expressing allogeneic renal cell carcinoma immunotherapy in patients with metastatic renal cell cancer
by Hammers, Hans J and Drake, Charles G and Zakharia, Yousef and Kennedy, Eugene Paul and Vahanian, Nicholas N and Link, Charles J and Agarwal, Neeraj
Journal of Clinical Oncology, ISSN 0732-183X, 02/2017, Volume 35, Issue 6_suppl, pp. 528 - 528
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13. Full Text An open-label, phase 2 study of nivolumab in combination with either rucaparib, docetaxel, or enzalutamide in men with castration-resistant metastatic prostate cancer (mCRPC; CheckMate 9KD)
by Fizazi, Karim and Drake, Charles G and Shaffer, David R and Pachynski, Russell and Saad, Fred and Ciprotti, Marika and Kong, George and Ryan, Charles J and Petrylak, Daniel Peter
Journal of Clinical Oncology, ISSN 0732-183X, 05/2018, Volume 36, Issue 15_suppl, pp. TPS3126 - TPS3126
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14. Full Text Preclinical development of combination therapy targeting the dominant cytokine interleukin-1β for renal cell carcinoma
by Aggen, David Henry and Ghasemzadeh, Ali and Mao, Wendy and Chowdhury, Nivi and Chaimowitz, Matthew and Hawley, Jessica and Wang, Vinson and Dallos, Matthew and Zhang, Cheng and Li, Hu and Guo, Xinzheng Victor and Drake, Charles G
Journal of Clinical Oncology, ISSN 0732-183X, 05/2019, Volume 37, Issue 15_suppl, pp. e14237 - e14237
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15. Full Text A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth
by Wang, Etienne C.E and Dai, Zhenpeng and Ferrante, Anthony W and Drake, Charles G and Christiano, Angela M
Cell Stem Cell, ISSN 1934-5909, 04/2019, Volume 24, Issue 4, pp. 654 - 669.e6
Hair growth can be induced from resting mouse hair follicles by topical application of JAK inhibitors, suggesting that JAK-STAT signaling is required for... 
stem cells | macrophages | TREM2 | hair cycle | hair growth | Oncostatin M | PROGENITORS | ACTIVATION | IMMUNE-SYSTEM | COLONY-STIMULATING FACTOR | TISSUE | NICHE | CYTOKINE FAMILY | SKIN | PRECURSORS | CYCLE | CELL & TISSUE ENGINEERING | CELL BIOLOGY
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16. Immunotherapy for Prostate Cancer
by Venturini, NJ and Drake, CG
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE, ISSN 2157-1422, 05/2019, Volume 9, Issue 5
Immunotherapy with agents that block immune checkpoints is a mainstay of therapy for several common tumor types; so far, prostate cancer is not among those... 
MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNITY | PEMBROLIZUMAB | THERAPY | MELANOMA | SURFACE | INNATE | MECHANISMS | PD-1 | EXPRESSION | CHECKPOINT BLOCKADE
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17. Full Text Gone baby gone - But how?
by Drake, Charles G
Blood, ISSN 0006-4971, 12/2012, Volume 120, Issue 24, pp. 4664 - 4666
CELLS | ANTIBODY | HEMATOLOGY | SAFETY | CANCER | TOLERANCE | Endothelial Cells - immunology | Animals | Programmed Cell Death 1 Receptor - immunology | CD8-Positive T-Lymphocytes - immunology | Immune Tolerance - immunology | B7-H1 Antigen - immunology
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18. Full Text Radiation and checkpoint blockade immunotherapy: radiosensitisation and potential mechanisms of synergy
by Sharabi, Andrew B, Dr and Lim, Michael, MD and DeWeese, Theodore L, Prof and Drake, Charles G, Prof
Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 13, pp. e498 - e509
Summary Checkpoint blockade immunotherapy has received mainstream attention as a result of striking and durable clinical responses in some patients with... 
Hematology, Oncology and Palliative Medicine | MHC CLASS-I | BREAST-CANCER | CALRETICULIN EXPOSURE | DENDRITIC CELLS | ONCOLOGY | ANTITUMOR IMMUNE-RESPONSES | ADVANCED MELANOMA | PROSTATE-CANCER | TUMOR-CELLS | IONIZING-RADIATION | CD8(+) T-CELLS | Cell Death - radiation effects | Immunotherapy - methods | Dendritic Cells - immunology | Humans | Radiation Tolerance | Antibodies, Monoclonal - therapeutic use | Molecular Targeted Therapy | Radiation-Sensitizing Agents - therapeutic use | CD8-Positive T-Lymphocytes - radiation effects | Neoplasms - therapy | Dendritic Cells - drug effects | Cell Death - drug effects | Signal Transduction - radiation effects | Cytotoxicity, Immunologic - drug effects | Chemoradiotherapy - methods | Treatment Outcome | Lymphocytes, Tumor-Infiltrating - drug effects | Radiation Dosage | Dendritic Cells - diagnostic imaging | Radiography | Animals | Signal Transduction - drug effects | Neoplasms - immunology | CD8-Positive T-Lymphocytes - drug effects | CD8-Positive T-Lymphocytes - immunology | Neoplasms - pathology | Cytotoxicity, Immunologic - radiation effects | Lymphocytes, Tumor-Infiltrating - radiation effects | Lymphocytes, Tumor-Infiltrating - immunology | Chemotherapy | Lung cancer | Analysis | Immunotherapy | Melanoma | Radiation | Lymphomas | Cancer
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19. Full Text Abstract LB-118: A conserved checkpoint molecule signature offers novel targets for tumor specific regulatory T cell manipulation
by Freeman, Zachary T and Hovleson, Daniel H and Pearson, Alexander T and Zhai, Jingyi and Ghasemzadeh, Ali and Nirschl, Thomas R and Jiang, Hui and Tomlins, Scott A and Drake, Charles G
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. LB-118 - LB-118
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20. Full Text Prostate cancer
by Attard, Gerhardt, MD and Parker, Chris, FRCR and Eeles, Ros A, FRCR and Schröder, Fritz, Prof and Tomlins, Scott A, MD and Tannock, Ian, MD and Drake, Charles G, MD and de Bono, Johann S, Prof
Lancet, The, ISSN 0140-6736, 2016, Volume 387, Issue 10013, pp. 70 - 82
Summary Much progress has been made in research for prostate cancer in the past decade. There is now greater understanding for the genetic basis of familial... 
Internal Medicine | ANDROGEN-DEPRIVATION THERAPY | PHASE-III TRIAL | ZOLEDRONIC ACID | MEDICINE, GENERAL & INTERNAL | MITOXANTRONE PLUS PREDNISONE | CIRCULATING TUMOR-CELLS | SURVIVAL ANALYSIS | ABIRATERONE ACETATE | RADICAL PROSTATECTOMY | ANTITUMOR-ACTIVITY | I CLINICAL-TRIAL | Prostatic Neoplasms - metabolism | Proto-Oncogene Proteins c-ets - genetics | Humans | Male | Antineoplastic Agents - therapeutic use | Prostatic Neoplasms - diagnosis | Prostatic Neoplasms, Castration-Resistant - genetics | Patient Selection | Prostatic Neoplasms - therapy | DNA-Binding Proteins - metabolism | Prostatic Neoplasms - genetics | Genes, BRCA2 | Prostatic Neoplasms, Castration-Resistant - therapy | Kallikreins - blood | Proto-Oncogene Proteins c-ets - metabolism | Genes, BRCA1 | DNA Helicases - genetics | PTEN Phosphohydrolase - genetics | Early Detection of Cancer | DNA-Binding Proteins - genetics | Prostate-Specific Antigen - blood | Carrier Proteins - genetics | DNA Helicases - metabolism | Carrier Proteins - metabolism | Biopsy | Androgen Antagonists - therapeutic use | Prostatectomy | Trypsin Inhibitor, Kazal Pancreatic | Prostatic Neoplasms, Castration-Resistant - diagnosis | Mortality | Genomics | United Kingdom | Diagnosis | Prostate cancer | Health aspects | Cancer | Studies | Mens health | Mutation
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