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Nature, ISSN 0028-0836, 04/2011, Volume 472, Issue 7344, pp. 466 - 470
Adult hippocampal neurogenesis is a unique form of neural circuit plasticity that results in the generation of new neurons in the dentate gyrus throughout... 
DEPRESSION | MODELS | MEMORY | MULTIDISCIPLINARY SCIENCES | NEURONS | DISORDER | DENTATE GYRUS | MATURATION | SYNAPTIC PLASTICITY | FLUOXETINE | BRAIN | Apoptosis - drug effects | Learning - drug effects | Neuronal Plasticity - drug effects | Male | Neural Stem Cells - cytology | Anxiety - therapy | Neuronal Plasticity - physiology | Long-Term Potentiation - drug effects | Exploratory Behavior - drug effects | Cognition - physiology | Long-Term Potentiation - physiology | Antidepressive Agents - pharmacology | bcl-2-Associated X Protein - deficiency | Extinction, Psychological - physiology | Cell Survival - drug effects | Synapses - drug effects | Conditioning, Classical - drug effects | Affect - physiology | bcl-2-Associated X Protein - metabolism | Anxiety - physiopathology | Mice, Transgenic | Hippocampus - pathology | Cognition - drug effects | Mice, Knockout | Dentate Gyrus - cytology | Aging - physiology | Dentate Gyrus - physiology | Mice | Dentate Gyrus - pathology | Hippocampus - physiopathology | Memory - physiology | Memory - drug effects | Aging - drug effects | Extinction, Psychological - drug effects | Fear - physiology | Dentate Gyrus - physiopathology | Exploratory Behavior - physiology | Synapses - metabolism | Fear - psychology | Female | Neurogenesis - drug effects | bcl-2-Associated X Protein - genetics | Neural Stem Cells - drug effects | Hippocampus - cytology | Physical Conditioning, Animal - physiology | Conditioning, Classical - physiology | Aging - pathology | Learning - physiology | Animals | Neurogenesis - physiology | Models, Neurological | Hippocampus - physiology | Neural Stem Cells - metabolism | Physiological aspects | Hippocampus (Brain) | Neurogenesis | Health aspects | Proteins | Studies | Young adults | Cognition & reasoning | Neurons | Anxieties | Rodents | Behavior | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 06/2015, Volume 522, Issue 7556, pp. 294 - 295
Might an engram that can affect anxiety be found elsewhere in the hippocampus or other regions of the brain? Because a single reactivation of the positive... 
Brain | Behavior | Mental depression | Anxieties | Neurons | Memory
Journal Article
Journal of the American Academy of Child & Adolescent Psychiatry, ISSN 0890-8567, 2015, Volume 54, Issue 8, pp. 613 - 614
Journal Article
Nature Neuroscience, ISSN 1097-6256, 12/2017, Volume 20, Issue 12, pp. 1657 - 1658
Journal Article
Journal of the American Academy of Child and Adolescent Psychiatry, ISSN 0890-8567, 8/2015, Volume 54, Issue 8, pp. 613 - 614
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 06/2011, Volume 70, Issue 5, pp. 908 - 923
Journal Article
Neuron, ISSN 0896-6273, 01/2010, Volume 65, Issue 1, pp. 40 - 52
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, pp. e84547 - e84547
Presenilin 1 (PSEN1) encodes the catalytic subunit of gamma-secretase, and PSEN1 mutations are the most common cause of early onset familial Alzheimer's... 
PLURIPOTENT STEM-CELLS | HUMAN ES | ACTIVATION | ADULT NEUROGENESIS | MULTIDISCIPLINARY SCIENCES | A-BETA | NEURONAL GENE-EXPRESSION | COLUMBIA-UNIVERSITY | 21ST-CENTURY BRAIN BANKING | TRANSGENIC MICE | PRESENILIN-1 | Neurons - pathology | Humans | Neurons - cytology | Gene Expression Profiling | Alzheimer Disease - pathology | Base Sequence | Cell Differentiation | Eye Proteins - genetics | Induced Pluripotent Stem Cells - metabolism | Cell Line | Brain - cytology | Amyloid beta-Peptides - biosynthesis | Gene Expression Regulation | Presenilin-1 - genetics | Rats | Suppressor of Cytokine Signaling Proteins - genetics | Genotype | Nerve Tissue Proteins - genetics | Peptide Fragments - biosynthesis | Animals | Apolipoproteins E - genetics | Presenilin-1 - metabolism | Adaptor Proteins, Signal Transducing - genetics | Brain - pathology | Mutation | Neural Stem Cells - metabolism | Genetic aspects | B cells | Alzheimer's disease | Stem cells | Target marketing | Profiling | Pathogenesis | Genomics | Biology | Kinases | Neurogenesis | 21st century | Fibroblasts | Aging | Catalysis | Departments | Neurodegenerative diseases | Neurons | Gene expression | Pathology | Neurology | Brain research | Presenilin 1 | Cells (biology) | Neural stem cells | Alzheimers disease | Psychiatry | Pluripotency | Secretase | Apoptosis | Inhibitory postsynaptic potentials | Index Medicus
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 4120 - 10
Early life stress predisposes to mental illness and behavioral dysfunction in adulthood, but the mechanisms underlying these persistent effects are poorly... 
RAT DENTATE GYRUS | NEUROGENIC NICHE | PROGENITORS | GLUCOCORTICOIDS | MULTIDISCIPLINARY SCIENCES | CONSEQUENCES | PROLIFERATION | DIFFERENTIATION | CHILDHOOD TRAUMA | REGULATE POSTNATAL-DEVELOPMENT | EXPRESSION | Dentate gyrus | Cell survival | Mental disorders | Stem cells | Stem cell transplantation | Bedding | Housing | Neurogenesis | Hippocampus | Structure-function relationships
Journal Article
Hippocampus, ISSN 1050-9631, 08/2018, Volume 28, Issue 8, pp. 586 - 601
Environmental exposures during early life, but not during adolescence or adulthood, lead to persistent reductions in neurogenesis in the adult hippocampal... 
adult neurogenesis | dentate gyrus | hippocampal stem cells | GFAP‐Tk | early postnatal neurogenesis | GFAP-Tk | FEAR MEMORY | MEMORY IMPAIRMENT | SUBVENTRICULAR ZONE | X-IRRADIATION | NEUROSCIENCES | YOUNG | CENTRAL-NERVOUS-SYSTEM | MICE | GRANULE CELLS | STRESS | Adults | Stem cells | Adolescence | Dentate gyrus | Nestin | Child development | Neural stem cells | Cell lineage | Neurogenesis | Hippocampus | Index Medicus
Journal Article
Cell Reports, ISSN 2211-1247, 10/2018, Volume 25, Issue 4, pp. 959 - 973.e6
Precisely deciphering the molecular mechanisms of age-related memory loss is crucial to create appropriate therapeutic interventions. We have previously shown... 
osteocalcin | RbAp48 | memory | aging | hippocampus | CIRCUITS | PATTERN SEPARATION | ADULT HIPPOCAMPAL NEUROGENESIS | COGNITIVE IMPAIRMENT | MICE | DENTATE GYRUS | GRANULE CELLS | RECEPTORS | SYNAPTIC PLASTICITY | BRAIN | CELL BIOLOGY
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 3, pp. e9777 - e9777
Journal Article
Cell Reports, ISSN 2211-1247, 01/2017, Volume 18, Issue 5, pp. 1144 - 1156
Lifelong homeostatic setpoints for mood-related behaviors emerge during adolescence. Serotonin (5-HT) plays an important role in refining the formation of... 
anxiety | DRN | serotonin | development | mPFC | 5-HT1A | adolescence | depression | 5-HT | DEPRESSION | FEEDBACK-CONTROL | EARLY ADULTHOOD | ANXIETY | CRITICAL PERIOD | NEURONS | BARREL CORTEX | ANIMAL-MODEL | DORSAL RAPHE NUCLEUS | BRAIN | CELL BIOLOGY | Index Medicus | Serotonin
Journal Article