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MOLECULAR PHARMACOLOGY, ISSN 0026-895X, 08/2019, Volume 96, Issue 2, pp. 193 - 203
The GluN2C subunit of the NMDA receptor is enriched in the neurons in the nucleus reticularis of the thalamus (nRT), but its role in regulating their function... 
SLEEP | CA2+ CHANNELS | FUNCTIONAL-ORGANIZATION | PHARMACOLOGY & PHARMACY | SK CHANNELS | NR2C SUBUNIT | RAT-BRAIN | EXPRESSION | STRUCTURAL DETERMINANTS | GLUN2D | CIRCUIT
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 09/2016, Volume 173, Issue 17, p. 2589
Agmatine, a putative neurotransmitter, plays a vital role in learning and memory. Although it is considered an endogenous ligand of imidazoline receptors,... 
Tyrosine | Nitric oxide | Rodents
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 09/2016, Volume 173, Issue 17, pp. 2589 - 2599
Background and Purpose Agmatine, a putative neurotransmitter, plays a vital role in learning and memory. Although it is considered an endogenous ligand of... 
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e60785
Glutamate delta-1 (GluD1) receptors are expressed throughout the forebrain during development with high levels in the hippocampus during adulthood. We have... 
KAINATE RECEPTORS | MESSENGER-RNAS | INHIBITORY PRESYNAPTIC DIFFERENTIATION | NMDA RECEPTORS | MULTIDISCIPLINARY SCIENCES | MEDIAL TEMPORAL-LOBE | LONG-TERM DEPRESSION | CANDIDATE GENES | AUTISM SPECTRUM DISORDER | SPATIAL MEMORY | SYNAPTIC PLASTICITY | Disks Large Homolog 4 Protein | Guanylate Kinases - genetics | Amygdala - physiopathology | Amygdala - drug effects | Depression - physiopathology | Prefrontal Cortex - physiopathology | Fear - drug effects | Memory, Short-Term - physiology | Receptors, Glutamate - deficiency | Hippocampus - drug effects | Depression - genetics | Emotions - drug effects | Prefrontal Cortex - drug effects | Fear - psychology | Behavior, Animal - drug effects | Cycloserine - pharmacology | Membrane Proteins - metabolism | Protein Isoforms - deficiency | Cues | Maze Learning - physiology | Receptors, Glutamate - genetics | Conditioning (Psychology) - drug effects | Membrane Proteins - genetics | Amygdala - metabolism | Glutamate Decarboxylase - genetics | Memory, Short-Term - drug effects | Maze Learning - drug effects | Mice, Knockout | Gene Expression Regulation - drug effects | Hippocampus - metabolism | Animals | Prefrontal Cortex - metabolism | Depression - psychology | Glutamate Decarboxylase - metabolism | Guanylate Kinases - metabolism | Mice | Hippocampus - physiopathology | Protein Isoforms - genetics | Psychological aspects | Memory consolidation | Cell receptors | Neural transmission | Models | Genetic aspects | Gene expression | Neurosciences | Amygdala | Memory | Foot shock | Central nervous system | Forebrain | Schizophrenia | Bipolar disorder | Mental depression | Cycloserine | Proteins | Learning | Receptors | Clonal deletion | Reversal learning | Rodents | Deletion | Behavior | Conditioning | Emotional behavior | Cortex (prefrontal) | Abnormalities | Inhibition (psychology) | Pharmacology | Glutamate decarboxylase | Pattern recognition | Object recognition | Maze learning | Latency | Fear conditioning | Studies | Fear | Autism | Brain research | DELTA protein | Aberration | Postsynaptic density | Laboratory animals | Short term memory | Postsynaptic density proteins | Hippocampus | Synapses | Latent inhibition
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 01/2011, Volume 79, Issue 6, pp. 1061 - 1071
Mouse embryonic spinal cord neurons in culture exhibit spontaneous calcium oscillations from day in vitro (DIV) 6 through DIV 10. Such spontaneous activity in... 
Journal Article
The Journal of Physiology, ISSN 0022-3751, 09/2008, Volume 586, Issue 18, pp. 4425 - 4439
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, p. e32969
The delta family of ionotropic glutamate receptors consists of glutamate d1 (GluD1) and glutamate delta 2 (GluD2) receptors. While the role of GluD2 in the... 
CASE-CONTROL ASSOCIATION | SCHIZOPHRENIA-SUSCEPTIBILITY GENE | MULTIDISCIPLINARY SCIENCES | SCAFFOLDING PROTEIN SHANK3 | MEDIAL TEMPORAL-LOBE | ASHKENAZI JEWISH FAMILIES | D-CYCLOSERINE | MAJOR DEPRESSION | AUTISM SPECTRUM DISORDERS | BIPOLAR DISORDER | PREFRONTAL CORTEX | Social Behavior Disorders - genetics | Gene Expression | Receptors, Glutamate - genetics | Aggression | Lithium - pharmacology | Mice, Inbred C57BL | Amygdala - metabolism | Male | Mice, 129 Strain | Depression - genetics | Social Behavior Disorders - drug therapy | Affective Symptoms - genetics | Mice, Knockout | Behavior, Animal | Depression - drug therapy | Anxiety - genetics | Animals | Gene Deletion | Prefrontal Cortex - metabolism | Lithium - administration & dosage | Mice | Physiological aspects | Bipolar disorder | Nervous system diseases | Social aspects | Glutamate | Cerebellum | Amygdala | Synaptogenesis | Mental disorders | Glutamic acid receptors (ionotropic) | Circuits | Hyperactivity | Genes | Central nervous system | Disorders | Schizophrenia | Lithium | Genomes | Glutamic acid receptors | Mental depression | Kinases | Cycloserine | Proteins | Receptors | Social behavior | Clonal deletion | Rodents | Deletion | Anxiety | Emotional behavior | Cortex (prefrontal) | Pharmacology | Behavior disorders | Intruder | Studies | Autism | Brain research | DELTA protein | Mutation | Aberration | Laboratory animals | Postsynaptic density proteins
Journal Article
The Journal of Physiology, ISSN 0022-3751, 03/2005, Volume 563, Issue 2, pp. 345 - 358
NR2A and NR2B are the predominant NR2 NMDA receptor subunits expressed in cortex and hippocampus. The relative expression level of NR2A and NR2B is regulated... 
Cell Line | Ion Channel Gating - physiology | Animals | Glutamic Acid - pharmacology | Signal Transduction | Synapses - physiology | Humans | Rats | Kinetics | Protein Subunits - physiology | Receptors, N-Methyl-D-Aspartate - physiology | Molecular and Genomic Physiology
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 05/2019, Volume 9, Issue 1, pp. 7572 - 11
The GluN2C- and GluN2D-containing NMDA receptors are distinct from GluN2A- and GluN2B-containing receptors in many aspects including lower sensitivity to Mg2+... 
POTENTIATION | PREPULSE INHIBITION | SUBTYPES | MULTIDISCIPLINARY SCIENCES | NR2A | RAT-BRAIN | STRESS | EXPRESSION | STARTLE | KETAMINE | CIRCUIT | Phenotypes | Phencyclidine | Mental disorders | Glutamic acid receptors (ionotropic) | Rodents | Schizophrenia | N-Methyl-D-aspartic acid receptors | Behavior | Magnesium
Journal Article
Journal Article
Neurobiology of Learning and Memory, ISSN 1074-7427, 05/2011, Volume 95, Issue 4, p. 404
  NR2C knockout mice exhibit deficit in cued and contextual fear conditioning. Conditioning-induced thalamo-amygdala synaptic strengthening is absent in NR2C... 
Journal Article