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Arthritis & Rheumatology, ISSN 2326-5191, 05/2017, Volume 69, Issue 5, pp. 964 - 975
Objective Prevotella copri, an intestinal microbe, may overexpand in stool samples from patients with new‐onset rheumatoid arthritis (RA), but it is not yet... 
TARGET | B-CELL RESPONSES | COMMENSAL | PEPTIDES | PERIODONTITIS | AUTOIMMUNITY | PORPHYROMONAS-GINGIVALIS | DISEASE | AUTOANTIGEN | RHEUMATOLOGY | REFRACTORY LYME ARTHRITIS | Humans | Middle Aged | Synovial Fluid - metabolism | Synovial Membrane - immunology | DNA, Ribosomal - metabolism | Male | Th1 Cells - immunology | Organothiophosphorus Compounds - immunology | Young Adult | Tandem Mass Spectrometry | Prevotella - immunology | Immunoglobulin G - immunology | Leukocytes, Mononuclear - immunology | Polymerase Chain Reaction | Aged, 80 and over | Adult | Female | Bacterial Proteins - immunology | Prevotella - genetics | Epitopes, T-Lymphocyte - immunology | DNA, Ribosomal - genetics | Enzyme-Linked Immunosorbent Assay | Peptides - immunology | Enzyme-Linked Immunospot Assay | Arthritis, Rheumatoid - microbiology | Gastrointestinal Microbiome - genetics | Immunoglobulin A - immunology | Aged | Gastrointestinal Microbiome - immunology | Arthritis, Rheumatoid - immunology | Peptides | Pathogenesis | Immunoglobulin G | Helper cells | Antibodies | Lymphocytes T | Arthritis | Assaying | Immunoglobulin A | Subgroups | Proteins | Synovial fluid | Antigenicity | Water analysis | Intestine | Direct reduction | Peripheral blood mononuclear cells | Feces | Digestive tract | Enzyme-linked immunosorbent assay | Deoxyribonucleic acid--DNA | Enzymes | Cytokines | Rheumatic diseases | Mass spectroscopy | Citrulline | Epitopes | Patients | Diseases | Polymerase chain reaction | Rheumatoid arthritis | Histocompatibility antigen HLA | Mass spectrometry
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2017, Volume 127, Issue 8, pp. 2946 - 2956
In rheumatoid arthritis (RA), immunological triggers at mucosal sites, such as the gut microbiota, may promote autoimmunity that affects joints. Here, we used... 
TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | NATURAL AUTOANTIBODIES | B-CELL RESPONSES | VIRUS | PORPHYROMONAS-GINGIVALIS | DISEASE | BACTEROIDES-THETAIOTAOMICRON | MOLECULAR MIMICRY | REFRACTORY LYME ARTHRITIS | HUMAN GUT SYMBIONT | Sulfatases - immunology | Filamins - immunology | Leukocytes, Mononuclear - metabolism | Enzyme-Linked Immunosorbent Assay | Humans | Gastrointestinal Microbiome | Joints - pathology | Synovial Membrane - metabolism | Epitopes - immunology | Arthritis, Rheumatoid - drug therapy | Autoimmunity - immunology | Immunoglobulin G - immunology | Joints - immunology | Autoantigens - immunology | Immunoglobulin A - immunology | Leukocytes, Mononuclear - immunology | Leukocytes, Mononuclear - cytology | HLA-DR Antigens - immunology | Arthritis, Rheumatoid - immunology | Antirheumatic Agents - therapeutic use | Autoantigens | Research | Microbiota (Symbiotic organisms) | T cells | Analysis | Rheumatoid arthritis | N-Acetylglucosamine-6-sulfatase | Mucosal immunity | Disease | Peptides | N-Acetylglucosamine | Mucosa | Leukocytes (mononuclear) | Homology | Lymphocytes T | Cell adhesion & migration | Proteins | Lymphocytes | Peripheral blood mononuclear cells | Antigens | Enzymes | T cell receptors | Citrulline | Epitopes | Joint diseases | Patients | Lymphocytes B | Alleles | Proteomics | Histocompatibility antigen HLA | Autoimmune diseases
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2018, Volume 13, Issue 4, pp. e0191926 - e0191926
CTLA-4 and CD28 exemplify a co-inhibitory and co-stimulatory signaling axis that dynamically sculpts the interaction of antigen-specific T cells with... 
UNTREATED MELANOMA | CYTOKINE RELEASE ASSAYS | LUNG-CANCER | IN-VITRO | MEDIATED CYTOTOXICITY | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | REGULATORY T-CELLS | CTLA-4 | ANTITUMOR ACTIVITIES | NIVOLUMAB PLUS IPILIMUMAB | Antineoplastic Agents, Immunological - toxicity | Epitope Mapping | Adjuvants, Immunologic - pharmacology | Antineoplastic Agents, Immunological - pharmacokinetics | Cricetulus | Cancer Vaccines - pharmacology | Humans | Immunoglobulin G - toxicity | Macaca fascicularis | Antineoplastic Agents, Immunological - chemistry | T-Lymphocytes, Regulatory - immunology | Adjuvants, Immunologic - pharmacokinetics | Neoplasms - therapy | Immunity, Cellular - drug effects | Adjuvants, Immunologic - chemistry | Immunoglobulin G - pharmacology | CHO Cells | Amino Acid Sequence | Immunoglobulin G - chemistry | Cells, Cultured | Models, Molecular | Adjuvants, Immunologic - toxicity | CTLA-4 Antigen - immunology | Antineoplastic Agents, Immunological - pharmacology | T-Lymphocytes, Regulatory - drug effects | Animals | Lymphocyte Activation - drug effects | Neoplasms - immunology | Antibody Formation - drug effects | CTLA-4 Antigen - antagonists & inhibitors | Toxicology | Pharmacology, Experimental | Research | Immunoglobulin G | Analysis | CD86 antigen | PD-1 protein | Lung cancer | Antibodies | Biochemistry | Lymphocytes T | CD28 antigen | Immunity | CTLA-4 protein | Lymphocytes | Immunotherapy | Combined vaccines | Primates | Repressing | Medical research | Immunoglobulins | Cytokines | Immunoregulation | Immunomodulation | Research & development--R&D | CD80 antigen | Pharmacology | T cell receptors | Chemical compounds | Signaling | Antigen-presenting cells | Biomarkers | Index Medicus | Research & development | R&D
Journal Article
by Böhm, Johann and Biancalana, Valérie and DeChene, Elizabeth T and Bitoun, Marc and Pierson, Christopher R and Schaefer, Elise and Karasoy, Hatice and Dempsey, Melissa A and Klein, Fabrice and Dondaine, Nicolas and Kretz, Christine and Haumesser, Nicolas and Poirson, Claire and Toussaint, Anne and Greenleaf, Rebecca S and Barger, Melissa A and Mahoney, Lane J and Kang, Peter B and Zanoteli, Edmar and Vissing, John and Witting, Nanna and Echaniz‐Laguna, Andoni and Wallgren‐Pettersson, Carina and Dowling, James and Merlini, Luciano and Oldfors, Anders and Bomme Ousager, Lilian and Melki, Judith and Krause, Amanda and Jern, Christina and Oliveira, Acary S. B and Petit, Florence and Jacquette, Aurélia and Chaussenot, Annabelle and Mowat, David and Leheup, Bruno and Cristofano, Michele and Poza Aldea, Juan José and Michel, Fabrice and Furby, Alain and Llona, Jose E. Barcena and Van Coster, Rudy and Bertini, Enrico and Urtizberea, Jon Andoni and Drouin‐Garraud, Valérie and Béroud, Christophe and Prudhon, Bernard and Bedford, Melanie and Mathews, Katherine and Erby, Lori A. H and Smith, Stephen A and Roggenbuck, Jennifer and Crowe, Carol A and Brennan Spitale, Allison and Johal, Sheila C and Amato, Anthony A and Demmer, Laurie A and Jonas, Jessica and Darras, Basil T and Bird, Thomas D and Laurino, Mercy and Welt, Selman I and Trotter, Cynthia and Guicheney, Pascale and Das, Soma and Mandel, Jean‐Louis and Beggs, Alan H and Laporte, Jocelyn and Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik and Göteborgs universitet and Gothenburg University and Institute of Biomedicine, Department of Pathology and Institute of Biomedicine, Department of Medical and Clinical Genetics and Sahlgrenska Academy and Institutionen för biomedicin, avdelningen för patologi and Sahlgrenska akademin
Human Mutation, ISSN 1059-7794, 06/2012, Volume 33, Issue 6, pp. 949 - 959
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Journal of Autoimmunity, ISSN 0896-8411, 2016, Volume 69, pp. 24 - 37
Journal Article