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CANCER IMMUNOLOGY IMMUNOTHERAPY, ISSN 0340-7004, 06/2019, Volume 68, Issue 6, pp. 983 - 990
BackgroundMerkel cell carcinoma (MCC) is an aggressive skin cancer in which PD-1/PD-L1 blockade has shown remarkable response rates. However, a significant... 
INDEPENDENT PREDICTOR | ONCOLOGY | Merkel cell carcinoma | Immunotherapy | HLA class-I | HDAC inhibitor | Infiltration | IMMUNOLOGY | Immunotherapy - methods | Skin Neoplasms - drug therapy | Humans | Middle Aged | Antibodies, Monoclonal - therapeutic use | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Carcinoma, Merkel Cell - drug therapy | Histocompatibility Antigens Class I - metabolism | Carcinoma, Merkel Cell - immunology | Aged, 80 and over | Female | Histone Deacetylase Inhibitors - immunology | Antibodies, Monoclonal - immunology | Skin Neoplasms - immunology | Carcinoma, Merkel Cell - genetics | Histocompatibility Antigens Class I - immunology | Drug Resistance, Neoplasm - immunology | Histocompatibility Antigens Class I - genetics | Down-Regulation - drug effects | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Down-Regulation - genetics | Drug Resistance, Neoplasm - genetics | B7-H1 Antigen - antagonists & inhibitors | Down-Regulation - immunology | Skin Neoplasms - genetics | Aged | Histone Deacetylase Inhibitors - therapeutic use | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | Drug Resistance, Neoplasm - drug effects | Antigens | Epigenetic inheritance | Carcinoma | Analysis | Skin | Metastasis | T cells | Skin cancer | Cancer | Histone deacetylase | Antigen presentation | PD-1 protein | CD8 antigen | Antigen processing | Clinical trials | Lymphocytes T | Reintroduction | Metastases | Major histocompatibility complex | PD-L1 protein | Histocompatibility antigen HLA
Journal Article
Der Hautarzt, ISSN 0017-8470, 3/2019, Volume 70, Issue 3, pp. 215 - 227
Das Merkelzellkarzinom ist ein seltener, hoch aggressiver Hauttumor des älteren Menschen. Er besitzt neuroendokrine Eigenschaften. Die Pathogenese ist mit... 
Prognose | Wächterlymphknotenbiopsie | Hauttumoren | Prognosis | Dermatology | Skin neoplasms | Polyomavirus | Allergology | Immunology | Medicine & Public Health | Immunotherapy | Sentinel lymph node biopsy | Immuntherapie | Proctology
Journal Article
Der Hautarzt, ISSN 0017-8470, 03/2019, Volume 70, Issue 3, p. 215
Das Merkelzellkarzinom ist ein seltener, hoch aggressiver Hauttumor des alteren Menschen. Er besitzt neuroendokrine Eigenschaften. Die Pathogenese ist mit... 
Chemotherapy | Immunotherapy | Skin | Metastasis | Cancer | Skin cancer
Journal Article
Der Onkologe, ISSN 0947-8965, 12/2018, Volume 24, Issue 12, pp. 1037 - 1049
Das Merkelzellkarzinom ist ein seltener, hoch aggressiver Hauttumor des älteren Menschen. Er besitzt neuroendokrine Eigenschaften. Die Pathogenese ist mit... 
Prognose | Wächterlymphknotenbiopsie | Hauttumoren | Prognosis | Medicine & Public Health | Skin neoplasms | Immunotherapy | Polyomavirus | Sentinel lymph node biopsy | Immuntherapie | Oncology
Journal Article
Onkologe, ISSN 0947-8965, 12/2018, Volume 24, Issue 12, pp. 1037 - 1049
Journal Article
Der Onkologe, ISSN 0947-8965, 12/2018, Volume 24, Issue 12, p. 1037
Das Merkelzellkarzinom ist ein seltener, hoch aggressiver Hauttumor des alteren Menschen. Er besitzt neuroendokrine Eigenschaften. Die Pathogenese ist mit... 
Chemotherapy | Immunotherapy | Skin | Metastasis | Cancer | Skin cancer
Journal Article
HAUTARZT, ISSN 0017-8470, 03/2019, Volume 70, Issue 3, pp. 215 - 225
Merkel cell carcinoma is arare, highly aggressive skin tumor with neuroendocrine features found in older people. The pathogenesis is associated with... 
Prognosis | PROGNOSTIC-FACTORS | Skin neoplasms | Immunotherapy | Polyomavirus | Sentinel lymph node biopsy | RISK | CHEMOTHERAPY | DERMATOLOGY
Journal Article
by Brinker, Titus J and Hekler, Achim and Enk, Alexander H and Enk, Alexander and Klode, Joachim and Hauschild, Axel and Berking, Carola and Schilling, Bastian and Haferkamp, Sebastian and Schadendorf, Dirk and Fröhling, Stefan and Utikal, Jochen Sven and Utikal, Jochen S and von Kalle, Christof and Ludwig-Peitsch, Wiebke and Sirokay, Judith and Heinzerling, Lucie and Albrecht, Magarete and Baratella, Katharina and Bischof, Lena and Chorti, Eleftheria and Dith, Anna and Drusio, Christina and Giese, Nina and Gratsias, Emmanouil and Griewank, Klaus and Hallasch, Sandra and Hanhart, Zdenka and Herz, Saskia and Hohaus, Katja and Jansen, Philipp and Jockenhöfer, Finja and Kanaki, Theodora and Knispel, Sarah and Leonhard, Katja and Martaki, Anna and Matei, Liliana and Matull, Johanna and Olischewski, Alexandra and Petri, Maximilian and Placke, Jan-Malte and Raub, Simon and Salva, Katrin and Schlott, Swantje and Sody, Elsa and Steingrube, Nadine and Stoffels, Ingo and Ugurel, Selma and Sondermann, Wiebke and Zaremba, Anne and Gebhardt, Christoffer and Booken, Nina and Christolouka, Maria and Buder-Bakhaya, Kristina and Bokor-Billmann, Therezia and Gholam, Patrick and Hänßle, Holger and Salzmann, Martin and Schäfer, Sarah and Schäkel, Knut and Schank, Timo and Bohne, Ann-Sophie and Deffaa, Sophia and Drerup, Katharina and Egberts, Friederike and Erkens, Anna-Sophie and Ewald, Benjamin and Falkvoll, Sandra and Gerdes, Sascha and Harde, Viola and Jost, Marion and Kosova, Katja and Messinger, Laetitia and Metzner, Malte and Morrison, Kirsten and Motamedi, Rogina and Pinczker, Anja and Rosenthal, Anne and Scheller, Natalie and Schwarz, Thomas and Stölzl, Dora and Thielking, Federieke and Tomaschewski, Elena and Wehkamp, Ulrike and Weichenthal, Michael and Wiedow, Oliver and Bär, Claudia Maria and Bender-Säbelkampf, Sophia and Horbrügger, Marc and Karoglan, Ante and Kraas, Luise and Faulhaber, Jörg and Geraud, Cyrill and Guo, Ze and Koch, Philipp and Linke, Miriam and Maurier, Nolwenn and Müller, Verena and Thomas, Benjamin and Alamri, Ali Saeed M and ... and Collaborators
European Journal of Cancer, ISSN 0959-8049, 04/2019, Volume 111, pp. 148 - 154
Recent studies have demonstrated the use of convolutional neural networks (CNNs) to classify images of melanoma with accuracies comparable to those achieved by... 
Diagnostics | Artificial intelligence | Melanoma | Skin cancer | DIAGNOSIS | ONCOLOGY | ALGORITHMS | Neural networks | Computer vision | Evaluation | Dermatology | Artificial neural networks | Colleges & universities | Sensitivity | Digital imaging | Classification | Machine learning | Photographs | Image classification
Journal Article
by Maron, Roman C and Weichenthal, Michael and Utikal, Jochen S and Utikal, Jochen and Hekler, Achim and Berking, Carola and Hauschild, Axel and Enk, Alexander H and Enk, Alexander and Haferkamp, Sebastian and Klode, Joachim and Schadendorf, Dirk and Jansen, Philipp and Holland-Letz, Tim and Schilling, Bastian and von Kalle, Christof and Fröhling, Stefan and Gaiser, Maria R and Hartmann, Daniela and Gesierich, Anja and Kähler, Katharina C and Wehkamp, Ulrike and Karoglan, Ante and Bär, Claudia and Brinker, Titus J and Schmitt, Laurenz and Peitsch, Wiebke K and Hoffmann, Friederike and Becker, Jürgen C and Drusio, Christina and Lodde, Georg and Sammet, Stefanie and Sondermann, Wiebke and Ugurel, Selma and Zader, Jeannine and Salzmann, Martin and Schäfer, Sarah and Schäkel, Knut and Winkler, Julia and Wölbing, Priscilla and Asper, Hiba and Bohne, Ann-Sophie and Brown, Victoria and Burba, Bianca and Deffaa, Sophia and Dietrich, Matthias and Dietrich, Cecilia and Drerup, Katharina Antonia and Egberts, Friederike and Erkens, Anna-Sophie and Greven, Salim and Harde, Viola and Jost, Marion and Kaeding, Merit and Kosova, Katharina and Lischner, Stephan and Maagk, Maria and Messinger, Anna Laetitia and Metzner, Malte and Motamedi, Rogina and Rosenthal, Ann-Christine and Seidl, Ulrich and Stemmermann, Jana and Torz, Kaspar and Velez, Juliana Giraldo and Haiduk, Jennifer and Alter, Mareike and Bergenthal, Paul and Gerlach, Anne and Holtorf, Christian and Kindermann, Sophie and Kraas, Luise and Felcht, Moritz and Klemke, Claus-Detlev and Kurzen, Hjalmar and Leibing, Thomas and Müller, Verena and Reinhard, Raphael R and Winter, Franziska and Eicher, Laurie and Heppt, Markus and Kilian, Katharina and Krammer, Sebastian and Lill, Diana and Niesert, Anne-Charlotte and Oppel, Eva and Sattler, Elke and Senner, Sonja and Wallmichrath, Jens and Wolff, Hans and Giner, Tina and Glutsch, Valerie and Kerstan, Andreas and Presser, Dagmar and Schrüfer, Philipp and Schummer, Patrick and Stolze, Ina and Weber, Judith and Drexler, Konstantin and Mickler, Marion and ... and Collabrators
European Journal of Cancer, ISSN 0959-8049, 09/2019, Volume 119, pp. 57 - 65
Recently, convolutional neural networks (CNNs) systematically outperformed dermatologists in distinguishing dermoscopic melanoma and nevi images. However, such... 
Artificial intelligence | Melanoma | Skin cancer screening | Skin cancer | ONCOLOGY | LEVEL CLASSIFICATION | Diagnosis | Neural networks | Cancer
Journal Article
by Brinker, Titus J and Hekler, Achim and Enk, Alexander H and Enk, Alexander and Klode, Joachim and Hauschild, Axel and Berking, Carola and Schilling, Bastian and Haferkamp, Sebastian and Schadendorf, Dirk and Holland-Letz, Tim and Utikal, Jochen Sven and Utikal, Jochen S and von Kalle, Christof and Ludwig-Peitsch, Wiebke and Sirokay, Judith and Heinzerling, Lucie and Albrecht, Magarete and Baratella, Katharina and Bischof, Lena and Chorti, Eleftheria and Dith, Anna and Drusio, Christina and Giese, Nina and Gratsias, Emmanouil and Griewank, Klaus and Hallasch, Sandra and Hanhart, Zdenka and Herz, Saskia and Hohaus, Katja and Jansen, Philipp and Jockenhöfer, Finja and Kanaki, Theodora and Knispel, Sarah and Leonhard, Katja and Martaki, Anna and Matei, Liliana and Matull, Johanna and Olischewski, Alexandra and Petri, Maximilian and Placke, Jan-Malte and Raub, Simon and Salva, Katrin and Schlott, Swantje and Sody, Elsa and Steingrube, Nadine and Stoffels, Ingo and Ugurel, Selma and Zaremba, Anne and Gebhardt, Christoffer and Booken, Nina and Christolouka, Maria and Buder-Bakhaya, Kristina and Bokor-Billmann, Therezia and Gholam, Patrick and Hänßle, Holger and Salzmann, Martin and Schäfer, Sarah and Schäkel, Knut and Schank, Timo and Bohne, Ann-Sophie and Deffaa, Sophia and Drerup, Katharina and Egberts, Friederike and Erkens, Anna-Sophie and Ewald, Benjamin and Falkvoll, Sandra and Gerdes, Sascha and Harde, Viola and Jost, Marion and Kosova, Katja and Messinger, Laetitia and Metzner, Malte and Morrison, Kirsten and Motamedi, Rogina and Pinczker, Anja and Rosenthal, Anne and Scheller, Natalie and Schwarz, Thomas and Stölzl, Dora and Thielking, Federieke and Tomaschewski, Elena and Wehkamp, Ulrike and Weichenthal, Michael and Wiedow, Oliver and Bär, Claudia Maria and Bender-Säbelkampf, Sophia and Horbrügger, Marc and Karoglan, Ante and Kraas, Luise and Faulhaber, Jörg and Geraud, Cyrill and Guo, Ze and Koch, Philipp and Linke, Miriam and Maurier, Nolwenn and Müller, Verena and Thomas, Benjamin and Alamri, Ali Saeed M and Baczako, Andrea and ... and Collaborators
European Journal of Cancer, ISSN 0959-8049, 05/2019, Volume 113, pp. 47 - 54
Recent studies have successfully demonstrated the use of deep-learning algorithms for dermatologist-level classification of suspicious lesions by the use of... 
Artificial intelligence | Melanoma | Skin cancer | DIAGNOSIS | ALGORITHMS | ONCOLOGY | Neural networks | Analysis | Medical personnel | Level (quantity) | Dermatology | Physicians | Artificial neural networks | Colleges & universities | Learning | Learning algorithms | Sensitivity | Algorithms | Classification | Machine learning | Lesions | Image classification
Journal Article
by Hekler, Achim and Utikal, Jochen S and Utikal, Jochen and Enk, Alexander H and Enk, Alexander and Hauschild, Axel and Weichenthal, Michael and Maron, Roman C and Berking, Carola and Haferkamp, Sebastian and Klode, Joachim and Schadendorf, Dirk and Schilling, Bastian and Holland-Letz, Tim and Izar, Benjamin and von Kalle, Christof and Fröhling, Stefan and Brinker, Titus J and Schmitt, Laurenz and Peitsch, Wiebke K and Hoffmann, Friederike and Becker, Jürgen C and Drusio, Christina and Jansen, Philipp and Lodde, Georg and Sammet, Stefanie and Sondermann, Wiebke and Ugurel, Selma and Zader, Jeannine and Salzmann, Martin and Schäfer, Sarah and Schäkel, Knut and Winkler, Julia and Wölbing, Priscilla and Asper, Hiba and Bohne, Ann-Sophie and Brown, Victoria and Burba, Bianca and Deffaa, Sophia and Dietrich, Cecilia and Dietrich, Matthias and Drerup, Katharina Antonia and Egberts, Friederike and Erkens, Anna-Sophie and Greven, Salim and Harde, Viola and Jost, Marion and Kaeding, Merit and Kosova, Katharina and Lischner, Stephan and Maagk, Maria and Messinger, Anna Laetitia and Metzner, Malte and Motamedi, Rogina and Rosenthal, Ann-Christine and Seidl, Ulrich and Stemmermann, Jana and Torz, Kaspar and Velez, Juliana Giraldo and Haiduk, Jennifer and Alter, Mareike and Bär, Claudia and Bergenthal, Paul and Gerlach, Anne and Holtorf, Christian and Karoglan, Ante and Kindermann, Sophie and Kraas, Luise and Felcht, Moritz and Gaiser, Maria R and Klemke, Claus-Detlev and Kurzen, Hjalmar and Leibing, Thomas and Müller, Verena and Reinhard, Raphael R and Winter, Franziska and Eicher, Laurie and Hartmann, Daniela and Heppt, Markus and Kilian, Katharina and Krammer, Sebastian and Lill, Diana and Niesert, Anne-Charlotte and Oppel, Eva and Sattler, Elke and Senner, Sonja and Wallmichrath, Jens and Wolff, Hans and Gesierich, Anja and Giner, Tina and Glutsch, Valerie and Kerstan, Andreas and Presser, Dagmar and Schrüfer, Philipp and Schummer, Patrick and Stolze, Ina and Weber, Judith and Drexler, Konstantin and Mickler, Marion and Stauner, Camila Toledo and ... and Collaborators
European Journal of Cancer, ISSN 0959-8049, 10/2019, Volume 120, pp. 114 - 121
Journal Article
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 21, pp. 1395 - 1395
Abstract Abstract 1395 Aberrant hypermethylation of tumor suppressor genes plays an important role in the development of acute myeloid leukemia (AML). In order... 
Journal Article
Deutsche Apotheker Zeitung, ISSN 0011-9857, 2018, Volume 158, Issue 30
Journal Article
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