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Immunity, ISSN 1074-7613, 02/2011, Volume 34, Issue 2, pp. 213 - 223
Type I interferon (IFN) is a common therapy for autoimmune and inflammatory disorders, yet the mechanisms of action are largely unknown. Here we showed that... 
FAMILIAL MEDITERRANEAN FEVER | MULTIPLE-SCLEROSIS | CASPASE-1 | HOST-DEFENSE | INNATE | CRYSTALS | RECOMBINANT INTERLEUKIN-1 | MICE | BACTERIAL-INFECTION | IMMUNOLOGY | RECEPTOR ANTAGONIST | Interleukin-1 - genetics | Inflammasomes - metabolism | STAT1 Transcription Factor - deficiency | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Monocytes - metabolism | Monocytes - immunology | Interleukin-10 - physiology | Interleukin-1 - biosynthesis | Interferon-beta - therapeutic use | Interferon Type I - biosynthesis | STAT3 Transcription Factor - physiology | Candida albicans - physiology | Interferon Type I - physiology | Caspase 1 - physiology | Candidiasis - immunology | Carrier Proteins - physiology | Peritonitis - etiology | STAT1 Transcription Factor - physiology | Poly I-C - pharmacology | Disease Susceptibility | Mice, Inbred C57BL | Peritonitis - immunology | STAT1 Transcription Factor - genetics | Gene Expression Regulation - drug effects | Animals | Candidiasis - etiology | Caspase 1 - genetics | Caspase 1 - deficiency | Interferon Type I - genetics | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Apoptosis Regulatory Proteins - physiology | Cells, Cultured - metabolism | Mice | Interferon Inducers - pharmacology | Multiple Sclerosis - drug therapy | Interferon | Infections | Cytokines | Viral infections | Molecular weight | Immune system
Journal Article
Neurology, ISSN 0028-3878, 08/2016, Volume 87, Issue 9, pp. e91 - e96
An 82-year-old right-handed woman presenting with a sudden-onset language deficit was initially evaluated in a regional hospital, with an unremarkable head MRI... 
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2010, Volume 120, Issue 3, pp. 713 - 719
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions (cataplexy). Narcolepsy... 
MEDICINE, RESEARCH & EXPERIMENTAL | PEPTIDES | NEURONS | UVEITIS | CATAPLEXY | MICE | NORMALIZATION | AUTOANTIBODY | ONSET | HYPOCRETIN OREXIN | Neurons - pathology | Narcolepsy - blood | Autoantigens - metabolism | Autoantibodies - blood | Humans | Sleep Initiation and Maintenance Disorders - pathology | Intracellular Signaling Peptides and Proteins - immunology | Male | Intracellular Signaling Peptides and Proteins - metabolism | Autoantigens - genetics | Autoimmune Diseases - genetics | Time Factors | Female | Neurons - metabolism | Neuropeptides - genetics | Autoimmune Diseases - pathology | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Narcolepsy - pathology | Hypothalamus - immunology | Severity of Illness Index | Orexins | Autoimmune Diseases - immunology | Neurons - immunology | Protein-Serine-Threonine Kinases - genetics | Mice, Transgenic | Neuropeptides - metabolism | Hypothalamus - pathology | Calcium-Calmodulin-Dependent Protein Kinases | Sleep Initiation and Maintenance Disorders - blood | Autoimmune Diseases - blood | Narcolepsy - immunology | Narcolepsy - genetics | Autoantibodies - immunology | Animals | Hypothalamus - metabolism | Sleep Initiation and Maintenance Disorders - immunology | Autoantigens - immunology | Sleep Initiation and Maintenance Disorders - genetics | Protein-Serine-Threonine Kinases - immunology | Mice | Neuropeptides - immunology | Usage | Care and treatment | Narcolepsy | Genetic aspects | Research | Gene expression | Enzyme-linked immunosorbent assay | Apoptosis
Journal Article
Brain, ISSN 0006-8950, 7/2008, Volume 131, Issue 7, pp. 1712 - 1721
Journal Article
Current Opinion in Neurology, ISSN 1350-7540, 06/2010, Volume 23, Issue 3, pp. 226 - 233
Purpose of review This review discusses demyelinating events of the nervous system that have been associated with new immunomodulatory treatments, in... 
MAbs | Multiple sclerosis | Natalizumab | Demyelination | Rituximab | Efalizumab | Antitumor necrosis factor-alpha agents | Progressive multifocal leukoencephalopathy | MULTIPLE-SCLEROSIS PATIENTS | ADVERSE DRUG EVENTS | multiple sclerosis | JC VIRUS-DNA | antitumor necrosis factor-alpha agents | GRANULE CELL NEURONOPATHY | HIV-NEGATIVE PATIENTS | NEUROSCIENCES | CYTOTOXIC T-LYMPHOCYTES | CLINICAL NEUROLOGY | TUMOR-NECROSIS-FACTOR | progressive multifocal leukoencephalopathy | demyelination | mAbs | ACTIVE ANTIRETROVIRAL THERAPY | efalizumab | natalizumab | rituximab | CEREBRAL PERIVASCULAR SPACES | Leukoencephalopathy, Progressive Multifocal - immunology | Demyelinating Diseases - physiopathology | Antibodies, Monoclonal, Murine-Derived | Humans | Antibodies, Monoclonal - adverse effects | Iatrogenic Disease - prevention & control | Nervous System - physiopathology | Antibodies, Monoclonal, Humanized | Leukoencephalopathy, Progressive Multifocal - chemically induced | Animals | Nervous System - drug effects | Tumor Necrosis Factor-alpha - immunology | Demyelinating Diseases - chemically induced | Immunologic Factors - adverse effects | Nervous System - immunology | Leukoencephalopathy, Progressive Multifocal - physiopathology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Demyelinating Diseases - drug therapy | Risk Assessment - standards | Psoriasis | Immunomodulation | Data processing | Nervous system | Risk factors | Necrosis | Infection | Reviews | Neurological complications | Monoclonal antibodies | Autoimmune diseases | CD11 antigen | Integrins
Journal Article