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Journal of Clinical Oncology, ISSN 0732-183X, 05/2019, Volume 37, Issue 15_suppl, pp. 10044 - 10044
Journal Article
Science, ISSN 0036-8075, 2019, Volume 363, Issue 6432, pp. 1175 - 1181
Cancer treatment decisions are increasingly based on the genomic profile of the patient's tumor, a strategy called "precision oncology." Over the past few... 
DABRAFENIB | INHIBITION | THERAPY | LANDSCAPE | TRAMETINIB | MULTIDISCIPLINARY SCIENCES | SYNERGY | CEREBLON | LEUKEMIA | MEDICINE | GENOME | Proteins | Medical research | Pediatrics | Transcription factors | Clinical trials | Case reports | Oncology | Children | Drug development | Patients | Cancer
Journal Article
European Journal of Cancer, ISSN 0959-8049, 05/2019, Volume 112, pp. 49 - 56
The lag time between initial human studies of oncology agents and the first-in-child clinical trials of these agents has not been defined. We conducted a... 
Paediatric cancer | Disparity | Drug development | Targeted therapy | Phase 1 trials | ONCOLOGY | CANCER GENOME | ADULTS | SURVIVORS | Respiratory agents | Drug approval | Analysis | Drugs | Medical research | Regulatory agencies | Indication | Clinical trials | Lag time | Oncology | FDA approval | Children
Journal Article
Pediatric Blood & Cancer, ISSN 1545-5009, 08/2019, Volume 66, Issue 8, pp. e27705 - n/a
Journal Article
Cancer, ISSN 0008-543X, 04/2019, Volume 125, Issue 8, pp. 1357 - 1364
Background Up to one‐third of patients with localized Ewing sarcoma (ES) develop recurrent disease, but current biomarkers do not accurately identify this... 
somatic mutations | Ewing sarcoma | somatic variants | stromal antigen 2 (STAG2) | tumor protein 53 (TP53) | OncoPanel | PROGNOSTIC-FACTORS | LANDSCAPE | TUMOR | CHEMOTHERAPY | P53 | FAMILY | STAG2 | ONCOLOGY | GENOMIC ALTERATIONS | BONE | Proteins | Sarcoma | Decision making | p53 Protein | Health risks | Biomarkers | Risk | Mutation | Diagnosis | Patients | Ewing's sarcoma | Cancer
Journal Article
Pediatric Blood & Cancer, ISSN 1545-5009, 11/2019, Volume 66, Issue 11, pp. e27938 - n/a
The therapies used to treat Ewing sarcoma are associated with a risk of second malignant neoplasm (SMN). We conducted a systematic review to pool available... 
second malignancy | Ewing sarcoma | acute myeloid leukemia | myelodysplastic syndrome | systematic review | osteosarcoma | LONG-TERM SURVIVORS | RISK | TUMORS | CHEMOTHERAPY | ADJUVANT | FAMILY | CHILDHOOD-CANCER | ONCOLOGY | PEDIATRICS | BONE | RADIOTHERAPY | LEUKEMIA | HEMATOLOGY | Sarcoma | Myeloid leukemia | Leukemia | Systematic review | Solid tumors | Acute myeloid leukemia | Myelodysplastic syndrome | Ewing's sarcoma | Tumors
Journal Article
JNCI: Journal of the National Cancer Institute, ISSN 0027-8874, 10/2019
Abstract The Research to Accelerate Cures and Equity (RACE) for Children Act was enacted in 2017 to authorize the FDA to require pediatric studies for new... 
Journal Article
by Sims, Rebecca and Van Der Lee, Sven J and Naj, Adam C and Bellenguez, Céline and Badarinarayan, Nandini and Jakobsdottir, Johanna and Kunkle, Brian W and Boland, Anne and Raybould, Rachel and Bis, Joshua C and Martin, Eden R and Grenier-Boley, Benjamin and Heilmann-Heimbach, Stefanie and Chouraki, Vincent and Kuzma, Amanda B and Sleegers, Kristel and Vronskaya, Maria and Ruiz, Agustin and Graham, Robert R and Olaso, Robert and Hoffmann, Per and Grove, Megan L and Vardarajan, Badri N and Hiltunen, Mikko and Nöthen, Markus M and White, Charles C and Hamilton-Nelson, Kara L and Epelbaum, Jacques and Maier, Wolfgang and Choi, Seung-Hoan and Beecham, Gary W and Dulary, Cécile and Herms, Stefan and Smith, Albert V and Funk, Cory C and Derbois, Céline and Forstner, Andreas J and Ahmad, Shahzad and Li, Hongdong and Bacq, Delphine and Harold, Denise and Satizabal, Claudia L and Valladares, Otto and Squassina, Alessio and Thomas, Rhodri and Brody, Jennifer A and Qu, Liming and Sánchez-Juan, Pascual and Morgan, Taniesha and Wolters, Frank J and Zhao, Yi and Garcia, Florentino Sanchez and Denning, Nicola and Fornage, Myriam and Malamon, John and Naranjo, Maria Candida Deniz and Majounie, Elisa and Mosley, Thomas H and Dombroski, Beth and Wallon, David and Lupton, Michelle K and Dupuis, Josée and Whitehead, Patrice and Fratiglioni, Laura and Medway, Christopher and Jian, Xueqiu and Mukherjee, Shubhabrata and Keller, Lina and Brown, Kristelle and Lin, Honghuang and Cantwell, Laura B and Panza, Francesco and McGuinness, Bernadette and Moreno-Grau, Sonia and Burgess, Jeremy D and Solfrizzi, Vincenzo and Proitsi, Petra and Adams, Hieab H and Allen, Mariet and Seripa, Davide and Pastor, Pau and Cupples, L Adrienne and Price, Nathan D and Hannequin, Didier and Frank-García, Ana and Levy, Daniel and Chakrabarty, Paramita and Caffarra, Paolo and Giegling, Ina and Beiser, Alexa S and Giedraitis, Vilmantas and Hampel, Harald and Garcia, Melissa E and Wang, Xue and Lannfelt, Lars and Mecocci, Patrizia and Eiriksdottir, Gudny and Crane, Paul K and Pasquier, Florence and Boccardi, Virginia and ... and EADI and GERAD PERADES and ARUKConsortium and CHARGE and ADGC and GERAD/PERADES, CHARGE, ADGC, EADI and ARUK Consortium and Stockholms universitet and Centrum för forskning om äldre och åldrande (ARC), (tills m KI) and Samhällsvetenskapliga fakulteten
Nature Genetics, ISSN 1061-4036, 09/2017, Volume 49, Issue 9, pp. 1373 - 1384
Journal Article
Radiology, ISSN 0033-8419, 2016, Volume 281, Issue 2, pp. 648 - 649
Journal Article
Pediatric Blood & Cancer, ISSN 1545-5009, 08/2019, Volume 66, Issue 8, pp. e27819 - n/a
Background MYCN amplification (MYCN‐A) is an established adverse prognostic factor in neuroblastoma. The extent to which the prognostic impact of MYCN‐A... 
context | neuroblastoma | amplification | MYCN | prognosis | SURVIVAL | MARKERS | ONCOGENE | PATHOLOGY CLASSIFICATION | ONCOLOGY | INFANTS | N-MYC | PEDIATRICS | HEMATOLOGY | Risk factors | Neuroblastoma | Mitosis | Decision making | Ferritin | Myc protein | Risk analysis | Subgroups | Confidence intervals | Amplification | Medical prognosis | Dependence | Health hazards
Journal Article
British Journal of Cancer, ISSN 0007-0920, 04/2019, Volume 120, Issue 8, pp. 869 - 869
The authors have noticed that the final paragraph of the Results section contains errors in the number of patients involved. The correct number of patients is... 
Bone cancer | Sarcoma | Osteosarcoma | Biocompatibility | Children | Patients | Ewing's sarcoma | Deoxyribonucleic acid--DNA | Tumors | Tumour biomarkers
Journal Article
Sarcoma, ISSN 1357-714X, 2018, Volume 2018, pp. 1712964 - 6
As of 2013, the WHO has classified peripheral primitive neuroectodermal tumors (PNETs) within the umbrella of Ewing sarcoma family of tumors (ESFTs) given... 
Medical research | Care and treatment | Analysis | Clinical trials | Medicine, Experimental | Research | Epidemiology | Ewing's sarcoma
Journal Article
Pediatric Blood & Cancer, ISSN 1545-5009, 11/2017, Volume 64, Issue 11, p. n/a
Purpose Accurate staging of neuroblastoma requires multiple imaging examinations. The purpose of this study was to determine the relative contribution of... 
MIBG | neuroblastoma staging | 99mTc‐MDP bone scan | 99mTc-MDP bone scan | Medicine, Experimental | Medical records | Medical research | Neuroblastoma | Identification methods | Estrogen | Technetium isotopes | Scintigraphy | Disease control | Patients | Metastases | Imaging | Tomography | Horses | Bone | Bone imaging | Cross sections
Journal Article