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Science Signaling, ISSN 1945-0877, 05/2018, Volume 11, Issue 529, p. eaat5326
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2015, Volume 194, Issue 8, pp. 3937 - 3952
Journal Article
Cellular Microbiology, ISSN 1462-5814, 11/2012, Volume 14, Issue 11, p. 1697
  Summary P2X7 receptors (P2X7R) are extracellular ATP-gated ion channels expressed in the immune effector cells that carry out critical protective responses... 
Proteins | Cytokines | Cellular biology | Cells
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2018, Volume 115, Issue 26, p. 6792
The inflammasomes are signaling platforms that promote the activation of inflammatory caspases such as caspases-1, -4, -5, and -11. Recent studies identified... 
Inhibitor drugs | Peptides | Lipids | Activation | Hydrophobicity | Macrophages | Caspase-3 | Hydrogen bonding | Inflammatory diseases | Caspase-1 | Cell activation | Hydrogen bonds | Cleavage | Catalysis | Crystal structure | Caspase | Inflammation | Peptide inhibitors | IL-1β | Domains | Signaling | Molecular modelling | Inhibitors | Cell death | Recognition | Apoptosis
Journal Article
Cellular Microbiology, ISSN 1462-5814, 11/2012, Volume 14, Issue 11, pp. 1697 - 1706
Journal Article
American Journal of Physiology-Cell Physiology, ISSN 0363-6143, 03/2013, Volume 304, Issue 5, pp. C403 - C405
Journal Article
The Ohio Journal of Science, ISSN 0030-0950, 04/2018, Volume 118, Issue 1, pp. A25 - A25
Inflammation is an innate immune response to stressors like pathogens and damaged cells, but when chronic, can lead to chronic inflammation and autoimmune... 
Immune response | Iodides | Calcium | Mortality | Neutrophils | Propidium iodide | Leukocytes (neutrophilic) | Inflammation | Cell membranes | Macrophages | Assaying | Progenitor cells | Proteins | Cell activation | Cell death | Cells (biology) | Pores | Porosity | Autoimmune diseases | Enzyme-linked immunosorbent assay | Pore formation | Apoptosis | Immune system
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 03/2008, Volume 28, Issue 3, pp. 425 - 435
Journal Article
The FEBS Journal, ISSN 1742-464X, 07/2013, Volume 280, Issue 14, p. 3365
  Previously, we reported that human [beta]-defensin (hBD)-3 can both antagonize CXCR4 function on T cells and promote receptor internalization in the absence... 
Immunology | Mutagenesis | Cellular biology | Ligands | T cell receptors | Biological assays
Journal Article
American Journal of Physiology-Cell Physiology, ISSN 0363-6143, 01/2011, Volume 300, Issue 1, pp. C11 - C13
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2007, Volume 282, Issue 26, pp. 18810 - 18818
Interleukin-1β (IL-1β) is a pro-inflammatory cytokine that plays an important role in host defense and inflammatory diseases. The maturation and secretion of... 
LISTERIA-MONOCYTOGENES | IL-1-BETA-CONVERTING ENZYME | IL-1-BETA SECRETION | MICE DEFICIENT | P2X RECEPTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | RELEASE | MATURATION | HUMAN MONOCYTES | ATP | INTERLEUKIN-1-BETA CONVERTING-ENZYME | Potassium - metabolism | Escherichia coli Infections - physiopathology | Lipopolysaccharides - metabolism | Caspase 1 - metabolism | Salmonella Infections - metabolism | Salmonella Infections - physiopathology | Salmonella typhimurium | Adenosine Triphosphate - pharmacology | Flagellin - pharmacology | Extracellular Space - metabolism | Mice, Mutant Strains | Adenosine Triphosphate - metabolism | Receptors, Purinergic P2 - genetics | Flagellin - metabolism | Macrophages - microbiology | Staphylococcus aureus | Staphylococcal Infections - metabolism | Calcium-Binding Proteins - metabolism | Listeriosis - metabolism | Escherichia coli Infections - metabolism | Apoptosis Regulatory Proteins - metabolism | Bacterial Infections - physiopathology | Receptors, Purinergic P2X7 | Macrophages - metabolism | Animals | Extracellular Space - microbiology | Listeriosis - physiopathology | Receptors, Purinergic P2 - metabolism | Lipopolysaccharides - pharmacology | Staphylococcal Infections - physiopathology | Cytosol - metabolism | Macrophages - drug effects | Cytosol - microbiology | Mice | Bacterial Infections - metabolism
Journal Article
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