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1. Full Text Metabolically healthy obesity and risk of mortality: Does the definition of metabolic health matter?
by Hinnouho, Guy-Marino and Czernichow, Sébastien and Dugravot, Aline and Batty, G. David and Kivimaki, Mika and Singh-Manoux, Archana
Diabetes Care, ISSN 0149-5992, 2013, Volume 36, Issue 8, pp. 2294 - 2300
OBJECTIVETo assess the association of a metabolically healthy obese phenotype with mortality using five definitions of metabolic health.RESEARCH DESIGN AND... 
INDIVIDUALS | PROFILE | INSULIN-RESISTANCE | GLUCOSE | OVERWEIGHT | ENDOCRINOLOGY & METABOLISM | CARDIOVASCULAR-DISEASE | BODY-MASS INDEX | COHORT | PREVALENCE | IDENTIFICATION | Body Mass Index | Humans | Middle Aged | Insulin Resistance | Proportional Hazards Models | Homeostasis | Male | Risk | Obesity - metabolism | Models, Biological | Adult | Female | Obesity - mortality | Health - classification | United Kingdom - epidemiology | Obesity | Health | Mortality | Cardiovascular diseases | France | Health aspects | Risk factors | Cholesterol | Life Sciences | Great Britain | Santé publique et épidémiologie | Original Research
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2. Full Text Timing of onset of cognitive decline: results from Whitehall II prospective cohort study
by Singh-Manoux, Archana and Kivimaki, Mika and Glymour, M Maria and Elbaz, Alexis and Berr, Claudine and Ebmeier, Klaus P and Ferrie, Jane E and Dugravot, Aline
BMJ, ISSN 0959-8138, 1/2012, Volume 344, Issue 7840, pp. 18 - 18
Objectives To estimate 10 year decline in cognitive function from longitudinal data in a middle aged cohort and to examine whether age cohorts can be compared... 
RESEARCH | Depopulation | Cohort studies | Predisposing factors | Epidemiology | Age | Age groups | Dementia | POPULATION | MEDICINE, GENERAL & INTERNAL | MIDDLE-AGE | DEMENTIA | ALZHEIMERS-DISEASE | ADULTS | HEALTH | LIFE | Cognition Disorders - physiopathology | Humans | Middle Aged | Aging - psychology | Male | Educational Status | Aging - pathology | Neuropsychological Tests - statistics & numerical data | Epidemiologic Methods | Age of Onset | Adult | Female | Aged | London - epidemiology | Cognition Disorders - epidemiology | Neuropsychological Tests | Life Sciences | Cognition Disorders | Aging | London | Santé publique et épidémiologie
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3. Full Text Physical activity, cognitive decline, and risk of dementia: 28 year follow-up of Whitehall II cohort study
by Sabia, Séverine and Dugravot, Aline and Dartigues, Jean-François and Abell, Jessica and Elbaz, Alexis and Kivimäki, Mika and Singh-Manoux, Archana
BMJ, ISSN 0959-8138, 6/2017, Volume 357, p. j2709
AbstractObjectiveTo test the hypotheses that physical activity in midlife is not associated with a reduced risk of dementia and that the preclinical phase of... 
POPULATION | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | PUBLIC-HEALTH | ALZHEIMERS-DISEASE | OLDER-ADULTS | PREVENTION | BRITISH CIVIL-SERVANTS | QUESTIONNAIRE | INTERVENTION | ASSOCIATION | Neuroprotection | Life Style | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Proportional Hazards Models | Dementia - physiopathology | Male | Cognitive Dysfunction - etiology | Cognitive Dysfunction - physiopathology | Health Behavior | Cognitive Dysfunction - prevention & control | Neuropsychological Tests | Dementia - etiology | Exercise | England - epidemiology | Aged, 80 and over | Adult | Female | Aged | Dementia - prevention & control
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4. Full Text Health behaviours, socioeconomic status, and mortality: Further analyses of the British Whitehall II and the French GAZEL prospective cohorts
by Stringhini, Silvia and Dugravot, Aline and Shipley, Martin and Goldberg, Marcel and Zins, Marie and Kivimäki, Mika and Marmot, Michael and Sabia, Séverine and Singh-Manoux, Archana
PLoS Medicine, ISSN 1549-1277, 02/2011, Volume 8, Issue 2, p. e1000419
Background: Differences in morbidity and mortality between socioeconomic groups constitute one of the most consistent findings of epidemiologic research.... 
EDUCATIONAL INEQUALITIES | MEDICINE, GENERAL & INTERNAL | SOCIAL-CLASS | RISK-FACTORS | LIFE-STYLE | EPIDEMIOLOGIC TRANSITION | WORKING-CONDITIONS | EUROPEAN COUNTRIES | CARDIOVASCULAR-DISEASES | CORONARY-HEART-DISEASE | COGNITIVE FUNCTION | Sedentary Lifestyle - ethnology | Smoking - adverse effects | France - epidemiology | Life Style | Prospective Studies | Diet - adverse effects | Health Status Disparities | Humans | Middle Aged | Proportional Hazards Models | Male | Alcohol Drinking - adverse effects | Social Class | Smoking - ethnology | Exercise | Cross-Cultural Comparison | Health Behavior - ethnology | Diet - ethnology | Adult | Female | Alcohol Drinking - ethnology | Longitudinal Studies | United Kingdom - epidemiology | Mortality - ethnology | Social classes | Demographic aspects | Mortality | United Kingdom | Health attitudes | France | Health aspects | Morbidity | Studies | Confidence intervals | White collar workers | Socioeconomic factors | Health behavior | Aging | Grants
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5. Full Text Alcohol consumption and risk of dementia: 23 year follow-up of Whitehall II cohort study
by Sabia, Séverine and Fayosse, Aurore and Dumurgier, Julien and Dugravot, Aline and Akbaraly, Tasnime and Britton, Annie and Kivimäki, Mika and Singh-Manoux, Archana
BMJ (Online), ISSN 0959-8146, 2018, Volume 362, p. k2927
OBJECTIVE To examine the association between alcohol consumption and risk of dementia. DESIGN Prospective cohort study. SETTING Civil service departments in... 
DOSE-RESPONSE METAANALYSIS | MEDICINE, GENERAL & INTERNAL | COGNITIVE DECLINE | DRINKING | ALZHEIMERS-DISEASE | MIDLIFE | BRITISH CIVIL-SERVANTS | OLD-AGE | DEATH | HEALTH | CAGE QUESTIONNAIRE | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Male | Dementia - epidemiology | Alcohol Drinking - epidemiology | Mental Health Services | Alcohol-Related Disorders - epidemiology | Adult | Female | Aged | London - epidemiology | Longitudinal Studies | Life Sciences | Human health and pathology
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6. Full Text Effect of intensity and type of physical activity on mortality: Results from the whitehall II cohort study
by Sabia, Séverine and Dugravot, Aline and Kivimaki, Mika and Brunner, Eric and Shipley, Martin J and Singh-Manoux, Archana
American Journal of Public Health, ISSN 0090-0036, 04/2012, Volume 102, Issue 4, pp. 698 - 704
Objectives. We examined the association of intensity and type of physical activity with mortality. Methods. We assessed the duration of physical activity by... 
ALL-CAUSE MORTALITY | HARVARD ALUMNI HEALTH | LEISURE-TIME | WOMEN | CARDIOVASCULAR-DISEASE MORTALITY | WALKING | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | MIDDLE-AGED MEN | FOLLOW-UP | LEVEL | CORONARY-HEART-DISEASE | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Male | Mortality - trends | Cause of Death | Adult | Female | Surveys and Questionnaires | Aged | Exercise - physiology | London - epidemiology | Longitudinal Studies | Cohort Studies | Exercise | Research | Health aspects | Mortality | Analysis | Physical fitness | Heart attacks | Leisure | Health services | Socioeconomic factors | Questionnaires | Cardiovascular disease | Life Sciences | London | Santé publique et épidémiologie | Research and Practice
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7. Full Text Decline in Fast Gait Speed as a Predictor of Disability in Older Adults
by Artaud, Fanny and Singh‐Manoux, Archana and Dugravot, Aline and Tzourio, Christophe and Elbaz, Alexis
Journal of the American Geriatrics Society, ISSN 0002-8614, 06/2015, Volume 63, Issue 6, pp. 1129 - 1136
Objectives To determine whether fast gait speed at study baseline and change in gait speed had independent associations with disability onset. Design Cohort... 
aged | epidemiology | cohort study | motor decline | disability | MORTALITY | PHYSICAL PERFORMANCE | RISK | PATTERNS | DEATH | LOWER-EXTREMITY FUNCTION | DISABLEMENT | GERIATRICS & GERONTOLOGY | MODELS | WALKING SPEED | GERONTOLOGY | HEALTH | Disability Evaluation | Confidence Intervals | France - epidemiology | Follow-Up Studies | Geriatric Assessment - statistics & numerical data | Humans | Male | Gait - physiology | Walking - physiology | Activities of Daily Living | Accidental Falls - prevention & control | Time Factors | Aged, 80 and over | Female | Aged | Postural Balance - physiology | Acceleration | Odds Ratio | Disabled Persons | Cohort Studies | Disabled persons | Activities of daily living | Analysis | Disability | Walking | Geriatrics
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8. Full Text Association of Midlife Diet with Subsequent Risk for Dementia
by Akbaraly, Tasnime N and Singh-Manoux, Archana and Dugravot, Aline and Brunner, Eric J and Kivimäki, Mika and Sabia, Séverine
JAMA - Journal of the American Medical Association, ISSN 0098-7484, 03/2019, Volume 321, Issue 10, pp. 957 - 968
IMPORTANCE Observational studies suggest that diet is linked to cognitive health. However, the duration of follow-up in many studies is not sufficient to take... 
MEDICINE, GENERAL & INTERNAL | MEMORY | ALZHEIMERS-DISEASE | MEDITERRANEAN DIET | FOLLOW-UP | PATTERNS | HEALTH | INTERVENTION | VALIDITY | COGNITIVE FUNCTION | DECLINE | Multivariate Analysis | Diet Surveys | Healthy Diet | Humans | Middle Aged | Male | Risk | Factor Analysis, Statistical | Dementia - epidemiology | Energy Intake | Health Behavior | Socioeconomic Factors | Incidence | Diet | Female | Cohort Studies | Usage | Questionnaires | Development and progression | Health aspects | Risk factors | Dementia | Adjustment | Cognitive ability | Dementia disorders | Population studies | Exposure | Dietary intake | Electronic medical records | Electronic health records | Original Investigation | Research
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9. Full Text Clinical, socioeconomic, and behavioural factors at age 50 years and risk of cardiometabolic multimorbidity and mortality: A cohort study
by Singh-Manoux, Archana and Fayosse, Aurore and Sabia, Séverine and Tabak, Adam and Shipley, Martin and Dugravot, Aline and Kivimäki, Mika
PLoS Medicine, ISSN 1549-1277, 05/2018, Volume 15, Issue 5, p. e1002571
Background Multimorbidity is increasingly common and is associated with adverse health outcomes, highlighting the need to broaden the single-disease framework... 
POPULATION | MEDICINE, GENERAL & INTERNAL | INEQUALITIES | DISEASE | FOLLOW-UP | PHYSICAL-ACTIVITY | HEALTH-CARE | PREVALENCE | WHITEHALL-II | ASSOCIATION | MULTIPLE CHRONIC CONDITIONS | Cardiovascular Diseases - etiology | Markov Chains | Humans | Middle Aged | Psychology | Risk Factors | Proportional Hazards Models | Male | Socioeconomic Factors | Multimorbidity | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Adult | Female | Aged | United Kingdom - epidemiology | Cohort Studies | Middle aged persons | Mortality | Economic aspects | Metabolic diseases | United Kingdom | Social aspects | Health aspects | Risk factors | Morbidity | Quality of life | Stroke (Disease) | Hypertension | Medical research | Hypercholesterolemia | Medicine, Experimental | Development and progression | Research | Coronary heart disease | Heart | Physical activity | Body weight | Cardiovascular disease | Systematic review | Socioeconomics | Genetics | Mathematical models | Heart diseases | Age | Stroke | Diabetes mellitus | Socio-economic aspects | Health risks | Risk analysis | Coronary artery disease | Socioeconomic factors | Alcoholic beverages | Death | Fatalities | Cardiovascular diseases | Health risk assessment | Smoking | Life Sciences | Human health and pathology | Cardiology and cardiovascular system | Psychiatrics and mental health
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10. Full Text Does cognitive reserve shape cognitive decline?
by Singh‐Manoux, Archana and Marmot, Michael G and Glymour, Maria and Sabia, Séverine and Kivimäki, Mika and Dugravot, Aline
Annals of Neurology, ISSN 0364-5134, 08/2011, Volume 70, Issue 2, pp. 296 - 304
Objective: Cognitive reserve is associated with a lower risk of dementia, but the extent to which it shapes cognitive aging trajectories remains unclear. Our... 
OLDER PERSONS | DEMENTIA | ALZHEIMERS-DISEASE | PREDICTORS | TRAJECTORIES | RISK | EDUCATION | NEUROSCIENCES | BRAIN | CLINICAL NEUROLOGY | AD PATHOLOGY | AGE | Biomarkers - metabolism | Cognition Disorders - physiopathology | Follow-Up Studies | Humans | Middle Aged | Cognition Disorders - pathology | Male | Neuropsychological Tests | Cognition - physiology | Adult | Female | Aged | Cognitive Reserve - physiology
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11. Full Text The gait speed advantage of taller stature is lost with age
by Elbaz, Alexis and Artaud, Fanny and Dugravot, Aline and Tzourio, Christophe and Singh-Manoux, Archana
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 1485 - 8
Taller individuals walk faster but it is unknown whether this advantage persists at older ages. We examined the cross-sectional/longitudinal associations of... 
FRACTURE | EVENTS | VASCULAR DEMENTIA | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | WALKING SPEED | BODY-MASS INDEX | RISK | HEIGHT | WEIGHT | DECLINE | Geriatric Assessment | Predictive Value of Tests | Cross-Sectional Studies | Humans | Risk Factors | Male | Gait - physiology | Aged, 80 and over | Body Height | Female | Aged | Walking Speed - physiology | Longitudinal Studies | Body Weights and Measures | Gait | Age
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12. Full Text Association between systolic blood pressure and dementia in theWhitehall II cohort study: Role of age, duration, and threshold used to define hypertension
by Abell, Jessica G and Kivimäki, Mika and Dugravot, Aline and Tabak, Adam G and Fayosse, Aurore and Shipley, Martin and Sabia, Séverine and Singh-Manoux, Archana
European Heart Journal, ISSN 0195-668X, 09/2018, Volume 39, Issue 33, pp. 3119 - 3125
Ageing | Blood pressure | Dementia
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13. Full Text Trajectories of Depressive Symptoms Before Diagnosis of Dementia: A 28-Year Follow-up Study
by Singh-Manoux, Archana and Dugravot, Aline and Fournier, Agnes and Abell, Jessica and Ebmeier, Klaus and Kivimäki, Mika and Sabia, Séverine
JAMA Psychiatry, ISSN 2168-622X, 07/2017, Volume 74, Issue 7, pp. 712 - 718
IMPORTANCE: Neuropsychiatric symptoms, depressive symptoms in particular, are common in patients with dementia but whether depressive symptoms in adulthood... 
OLDER PERSONS | COGNITIVE DECLINE | PSYCHIATRY | ALZHEIMERS-DISEASE | LATE-LIFE | BRITISH CIVIL-SERVANTS | RISK | GENERAL HEALTH QUESTIONNAIRE | VASCULAR-DEMENTIA | MAJOR DEPRESSION | TEMPORAL RELATIONSHIP | Depression - epidemiology | Follow-Up Studies | Comorbidity | Humans | Middle Aged | Risk | Dementia - epidemiology | Prodromal Symptoms | Incidence | Aged, 80 and over | Adult | Aged | United Kingdom - epidemiology | Complications and side effects | Depression, Mental | Diagnosis | Health aspects | Risk factors | Dementia | Online First | Original Investigation | Research
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