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Journal Article
Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, p. 5676
Efforts to compile the phenotypic effects of drugs and environmental chemicals offer the opportunity to adopt a chemo-centric view of human health that does... 
NETWORK MEDICINE | DATABASE | PHARMACOLOGY | MULTIDISCIPLINARY SCIENCES | DRUGS | CHEMISTRY | SYSTEMS | DIVERSITY | DISCOVERY | Disease - etiology | Chemistry | Phenotype | Health | Humans | Drug Therapy | Investigació mèdica | Medicine research | Salut pública | Public health
Journal Article
Structure, ISSN 0969-2126, 01/2016, Volume 24, Issue 1, pp. 116 - 126
Journal Article
Wiley Interdisciplinary Reviews: Computational Molecular Science, ISSN 1759-0876, 11/2019, Volume 9, Issue 6
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 09/2018, Volume 430, Issue 18, pp. 3016 - 3027
Cancer cell lines (CCLs) play an important role in the initial stages of drug discovery allowing, among others, for the screening of drug candidates. As CCL... 
drug response | cancer cell lines | network-based stratification | molecular signatures | antineoplastic drugs | NETWORK | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | SENSITIVITY | BRAF | DISCOVERY | PREDICTION | INHIBITION | GENE-EXPRESSION | MUTATIONS | PIDD
Journal Article
Genome Medicine, ISSN 1756-994X, 03/2019, Volume 11, Issue 1, pp. 1 - 15
BackgroundThe integration of large-scale drug sensitivity screens and genome-wide experiments is changing the field of pharmacogenomics, revealing molecular... 
SIGNALING PATHWAYS | PROTEIN | DATABASE | PANCREATIC-CANCER | GROWTH | GENETICS & HEREDITY | SENSITIVITY | RESISTANCE | RECEPTOR | EXPRESSION | SOMATIC MUTATIONS | Pharmacogenetics | Research | Genetic transcription | Gene expression | Analysis | Drugs | Transcription | Principal components analysis | Genomes | Biology | Breast cancer | Tumor cell lines | Kinases | Proteins | Pancreatic cancer | Cell lines | Mutation | Cancer
Journal Article
Genome medicine, 03/2019, Volume 11, Issue 1, p. 17
The integration of large-scale drug sensitivity screens and genome-wide experiments is changing the field of pharmacogenomics, revealing molecular determinants... 
Drug Resistance, Neoplasm - genetics | Algorithms | Humans | Cell Line, Tumor | Pharmacogenomic Variants | Gene Regulatory Networks | Genome-Wide Association Study - methods
Journal Article
Bioinformatics, ISSN 1367-4803, 02/2015, Volume 31, Issue 4, pp. 612 - 613
Journal Article
Genome Medicine, ISSN 1756-994X, 08/2018, Volume 10, Issue 1, pp. 61 - 8
Journal Article
Genome Medicine, ISSN 1756-994X, 01/2012, Volume 4, Issue 1, pp. 3 - 3
Side-effects are the unintended consequence of therapeutic treatments, but they can also be seen as valuable read-outs of drug effects in humans; these effects... 
Drug repositioning | Side effects | Polypharmacology | Mechanism of action | mechanism of action | drug repositioning | polypharmacology | GENETICS & HEREDITY | Drugs | Complications and side effects | Forecasts and trends | Drug discovery | Recycling (Waste, etc.)
Journal Article
Molecular Cancer, ISSN 1476-4598, 02/2015, Volume 14, Issue 1, p. 40
Background: Cancer cell lines have a prominent role in the initial stages of drug discovery, facilitating high-throughput screening of potential drugs.... 
Tissue specificity | Cancer cell lines | Drug sensitivity | BREAST-CANCER | ONCOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISCOVERY | TOOLS | Neoplasms - metabolism | Neoplasms - genetics | Humans | Cell Line, Tumor | Drug Resistance, Neoplasm | Antineoplastic Agents - pharmacology | Organ Specificity | Neoplasms - drug therapy | Health aspects | Drug discovery
Journal Article
Cell, ISSN 0092-8674, 02/2016, Volume 164, Issue 4, pp. 805 - 817
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 07/2017, Volume 45, Issue 1, pp. W195 - W200
The massive molecular profiling of thousands of cancer patients has led to the identification of many tumor type specific driver genes. However, only a few (or... 
VISUALIZATION | LIBRARY | MUTATIONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | Web Server Issue
Journal Article