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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2011, Volume 108, Issue 17, pp. 7142 - 7147
Trastuzumab, a monoclonal antibody targeting human epidermal growth factor receptor-2 (HER2/ErbB-2), has become the mainstay of treatment for HER2-positive... 
T lymphocytes | Inoculation | Medical treatment | Antibodies | Cytotoxicity | Breast cancer | Adaptive immunity | Natural killer cells | Tumors | Cancer | Natural killer cell | Innate | Adaptive | Tumor immunology | tumor immunology | TRASTUZUMAB | MECHANISM | MULTIDISCIPLINARY SCIENCES | innate | OVEREXPRESSING HER2 | COMBINATION | HER2-POSITIVE BREAST-CANCER | ADAPTIVE IMMUNITY | adaptive | IMMUNOTHERAPY | MICE | natural killer cell | PHASE-I | ESTABLISHED TUMORS | Receptor, ErbB-2 - genetics | Receptors, Interleukin-1 Type I - immunology | CD8-Positive T-Lymphocytes - transplantation | Humans | Receptors, Interleukin-17 - immunology | Receptors, Interleukin-17 - genetics | Tumor Necrosis Factor Receptor Superfamily, Member 9 - genetics | Adoptive Transfer | Interferon Type I - immunology | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Antibodies, Monoclonal, Humanized | Receptor, ErbB-2 - immunology | Interferon-gamma - genetics | Antibodies, Monoclonal - immunology | Mammary Neoplasms, Animal - genetics | Mammary Neoplasms, Animal - immunology | Antibodies, Monoclonal - pharmacology | Tumor Necrosis Factor Receptor Superfamily, Member 9 - immunology | Mice, Transgenic | Antineoplastic Combined Chemotherapy Protocols - immunology | Mice, SCID | Animals | Apoptosis Regulatory Proteins | Interferon-gamma - immunology | Receptors, Interleukin-1 Type I - genetics | Cell Line, Tumor | Interferon Type I - genetics | Programmed Cell Death 1 Receptor | Antigens, Surface | Mammary Neoplasms, Animal - drug therapy | Mice | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | Trastuzumab | Biological Sciences
Journal Article
Immunity, ISSN 1074-7613, 04/2013, Volume 38, Issue 4, pp. 729 - 741
Journal Article
Cancer Research, ISSN 0008-5472, 07/2011, Volume 71, Issue 14, pp. 4809 - 4820
Journal Article
Nature Cell Biology, ISSN 1465-7392, 07/2013, Volume 15, Issue 7, pp. 818 - 828
Dysfunctional telomeres suppress tumour progression by activating cell-intrinsic programs that lead to growth arrest. Increased levels of TRF2, a key factor in... 
DAMAGE RESPONSE | TELOMERE DYSFUNCTION | PROTECTION | IN-VIVO | ATM | END | HEPARAN-SULFATE PROTEOGLYCANS | PROTEINS | UP-REGULATION | EXPRESSION | CELL BIOLOGY | RNA, Small Interfering - genetics | Cell Proliferation | Breast Neoplasms - immunology | Colonic Neoplasms - prevention & control | Humans | Melanoma, Experimental - metabolism | Killer Cells, Natural - pathology | DNA Primers - chemistry | Colonic Neoplasms - metabolism | Breast Neoplasms - metabolism | Melanoma, Experimental - prevention & control | Flow Cytometry | Melanoma, Experimental - immunology | Colonic Neoplasms - immunology | Killer Cells, Natural - immunology | Female | Sulfotransferases - metabolism | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Sulfotransferases - genetics | Telomeric Repeat Binding Protein 2 - antagonists & inhibitors | RNA, Messenger - genetics | Discoidin Domain Receptor 1 | Receptor Protein-Tyrosine Kinases - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Cell Adhesion | Blotting, Western | Breast Neoplasms - prevention & control | Animals | Lymphocytes, Tumor-Infiltrating - pathology | Receptor Protein-Tyrosine Kinases - genetics | Mice, Nude | Telomeric Repeat Binding Protein 2 - metabolism | Mice | HeLa Cells | Killer Cells, Natural - metabolism | Telomeric Repeat Binding Protein 2 - genetics | Apoptosis | Lymphocytes, Tumor-Infiltrating - immunology | Killer cells | Colorectal cancer | Cancer cells | Development and progression | Genetic aspects | Research | Health aspects
Journal Article
Journal Article
Journal Article
European Journal of Immunology, ISSN 0014-2980, 07/2014, Volume 44, Issue 7, pp. 2111 - 2120
  The NLRP3 inflammasome plays a crucial role in the innate immune response to pathogens and exogenous or endogenous danger signals. Its activity must be... 
Tumor necrosis factor | Mice | Rodents | T cell receptors
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 11/2012, Volume 72, Issue 22, pp. 5721 - 5732
Journal Article
European Journal of Immunology, ISSN 0014-2980, 07/2014, Volume 44, Issue 7, pp. 2111 - 2120
Journal Article
Nature Communications, ISSN 2041-1723, 2011, Volume 2, Issue 1, pp. 202 - 202
Journal Article