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DMM Disease Models and Mechanisms, ISSN 1754-8403, 12/2017, Volume 10, Issue 12, pp. 1381 - 1389
For hundreds of years, biologists have studied accessible organisms such as garden peas, sea urchins collected at low tide, newt eggs, and flies circling... 
C. elegans | Yeast | Invertebrates | Sea urchin | Drosophila | GENETIC-CONTROL | DROSOPHILA-MELANOGASTER | DIVISION CYCLE | DORSAL-VENTRAL POLARITY | PATHOLOGY | MATERNAL MESSENGER-RNA | CELL BIOLOGY | PROGRAMMED CELL-DEATH | CHROMOSOMAL-PROTEIN | POSITION-EFFECT VARIEGATION | C-ELEGANS | PROMOTES APOPTOSIS | Special
Journal Article
Journal Article
Experimental Cell Research, ISSN 0014-4827, 12/2017, Volume 361, Issue 2, pp. 277 - 283
The bioactive sphingolipid ceramide 1-phosphate (C1P) regulates cell division in a variety of cell types including macrophages. However, the mechanisms... 
Cell proliferation | Ceramide 1-phosphate | Sphingolipids | Macrophages | VEGF | MIGRATION | SURVIVAL | ACTIVATION | CERAMIDE-1-PHOSPHATE | KINASE | HUMAN LUNG FIBROBLASTS | CELL-PROLIFERATION | VEGF-A | SPHINGOSINE 1-PHOSPHATE | CELL BIOLOGY | ONCOLOGY | BLOCKS APOPTOSIS | RNA, Small Interfering - genetics | Phosphatidylinositol 3-Kinases - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Vascular Endothelial Growth Factor A - genetics | Proto-Oncogene Proteins c-akt - genetics | Vascular Endothelial Growth Factor Receptor-2 - genetics | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Mitogen-Activated Protein Kinase 1 - genetics | Cell Membrane - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Cell Membrane - drug effects | Cell Line | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Antibodies, Neutralizing - pharmacology | Ceramides - antagonists & inhibitors | Macrophages - cytology | Pyrimidines - pharmacology | Cell Division - drug effects | Ceramides - pharmacology | Phosphatidylinositol 3-Kinases - genetics | Macrophages - metabolism | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Macrophages - drug effects | Mitogen-Activated Protein Kinases - genetics | Cell Proliferation - drug effects | Mice | Mitogen-Activated Protein Kinase 1 - metabolism | Mitogen-Activated Protein Kinases - metabolism | RNA, Small Interfering - metabolism | Phosphates | Membrane lipids | Pyrimidines | Developmental biology | Albumin | Genetic engineering | Vascular endothelial growth factor | Mitogens | Protein kinases | Index Medicus
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 1996, Volume 271, Issue 24, pp. 14514 - 14518
Journal Article
Journal Article
FEBS Letters, ISSN 0014-5793, 2005, Volume 579, Issue 17, pp. 3744 - 3750
In this report, we show for the first time that ceramide-1-phosphate (C1P) stimulates the phosphatidylinositol 3-kinase (PI3-K)/protein kinase B (PKB) pathway,... 
NF-κB | Protein kinase B | PI3-kinase | Sphingomyelinase | Ceramide-1-phosphate | Apoptosis | M-CSF | electromobility shift assay | PI (3,4,5) P3 | BMDM | acetyl | MTS | caffeic acid phenylethyl ester | thin-layer chromatography | PI3-K | Tris-buffered saline | MAPK/ERK kinase | bone marrow-derived macrophages | FBS | pertussis toxin | phosphatidylinositol 3-kinase | phosphatidylinositol (3,4,5) trisphosphate | TBS | acid sphingomyelinase | PKB | MAPK | fetal bovine serum | MEK | A-SMase | GAPDH | ERK | C1P | PLD | TLC | CAPE | mitogen-activated protein kinase | ceramide-1-phosphate | S1P | calcium-dependent cytosolic phospholipase A2 | PTX | EMSA | glyceraldehyde-3-phosphate dehydrogenase | 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt | protein kinase B | phospholipase D | cPLA2 | extracellular regulated kinase | macrophage colony stimulating factor | phosphatidylinositol | PMS | sphingosine-1-phosphate | phenazine methosulfate | octanoyl | BIOCHEMISTRY & MOLECULAR BIOLOGY | apoptosis | NEUTROPHILS | DNA-SYNTHESIS | INHIBITS MACROPHAGE APOPTOSIS | CELL BIOLOGY | CERAMIDE 1-PHOSPHATE | NF-kappa B | BIOPHYSICS | BLOCKS APOPTOSIS | GROWTH | sphingomyelinase | PI-3-KINASE | ACID SPHINGOMYELINASE | Proto-Oncogene Proteins - metabolism | Up-Regulation | bcl-X Protein | Proto-Oncogene Proteins - drug effects | Cell Survival | NF-kappa B - metabolism | Phosphatidylinositol 3-Kinases - metabolism | I-kappa B Proteins - metabolism | Ceramides - pharmacology | DNA-Binding Proteins - metabolism | Proto-Oncogene Proteins c-akt | Proto-Oncogene Proteins c-bcl-2 - metabolism | Macrophages - metabolism | Animals | Phosphatidylinositol 3-Kinases - drug effects | Protein-Serine-Threonine Kinases - drug effects | Female | Mice | Phosphorylation - drug effects | Ceramides - physiology | Bone Marrow Cells - metabolism | Protein-Serine-Threonine Kinases - metabolism | Phosphates | Phosphatidylinositol | Analysis | Sphingosine | Macrophage colony stimulating factor | Phospholipases | Macrophages | Protein kinases | Sugars | Monosaccharides
Journal Article