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Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2019, Volume 62, Issue 1, pp. 46 - 59
Kidney-type glutaminase (GLS), the first enzyme in the glutaminolysis pathway, catalyzes the hydrolysis of glutamine to glutamate. GLS was found to be... 
CELLS | ACTIVATION | DESIGN | CHEMISTRY, MEDICINAL | METABOLISM | MECHANISM | PHOSPHATE-DEPENDENT GLUTAMINASE | GLUTAMATE | GROWTH | EXPRESSION | BINDING
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 01/2019, Volume 27, Issue 2, pp. 255 - 264
Journal Article
Journal of medicinal chemistry, ISSN 0022-2623, 12/2012, Volume 55, Issue 23, pp. 10551 - 10563
Bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES) is a potent and selective allosteric inhibitor of kidney-type glutaminase (GLS) that has... 
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 10/2012, Volume 3, Issue 10, pp. 839 - 843
A series of 1-hydroxy-1H-benzo[d]imidazol-2(3H)-ones were synthesized and evaluated for their ability to inhibit human and porcine forms of d-amino acid... 
SERINE-INDUCED NEPHROTOXICITY | CHEMISTRY, MEDICINAL | D-serine | SCHIZOPHRENIA | NMDA receptors | D-amino acid oxidase (DAAO) | glucuronidation | DISCOVERY
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 09/2011, Volume 2, Issue 9, pp. 698 - 702
The synthesis of a stereochemically diverse library of medium-sized rings accessible via a "build/couple/pair" strategy is described. Key aspects of the... 
screening collection | beta cell | apoptosis | Diversity-oriented synthesis | diabetes | CYTOKINES | CHEMISTRY, MEDICINAL | STRATEGY | LIBRARY | TOXICITY | DISCOVERY | MOLECULES | CHEMICAL SPACE
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2008, Volume 51, Issue 12, pp. 3357 - 3359
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 10/2012, Volume 3, Issue 10, pp. 839 - 843
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 08/2004, Volume 69, Issue 16, pp. 5204 - 5211
Journal Article
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