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Biophysical Journal, ISSN 0006-3495, 02/2019, Volume 116, Issue 3, pp. 176a - 176a
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2018, Volume 115, Issue 50, pp. 12733 - 12738
The human proteome contains 826 G protein-coupled receptors (GPCR), which control a wide array of key physiological functions, making them important drug... 
Signaling | GPCR | Adenosine recepto | NMR spectroscopy | Dynamics | Biological Sciences | Physical Sciences | dynamics | signaling | adenosine receptor
Journal Article
Structure, ISSN 0969-2126, 12/2016, Volume 24, Issue 12, p. 2190
Fluorine-19 nuclear magnetic resonance (NMR) was used to study conformational equilibria at the intracellular tips of helices VI and VII in a variant... 
Crystals | Fluorides | Research institutes | G proteins | Structure | Ethanolamines | Lysozyme | Membrane proteins | Protein binding
Journal Article
Structure, ISSN 0969-2126, 12/2016, Volume 24, Issue 12, pp. 2190 - 2197
Fluorine-19 nuclear magnetic resonance (NMR) was used to study conformational equilibria at the intracellular tips of helices VI and VII in a variant β... 
fusion protein | membrane proteins | β2-adrenergic receptor | protein dynamics | solution nuclear magnetic resonance | structural biology | solution NMR | integrative structural biology | 19F NMR spectroscopy | G-protein-coupled receptors
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2018, Volume 115, Issue 50, p. 12733
brane to intracellular binding sites for partners such as G proteins and arrestins. This signaling process is related to dynamic equilibria in conformational... 
Proteins | Signaling | Adenosine | Nuclear magnetic resonance--NMR | Spectrum analysis | Proteomics | Activation | Qualitative analysis | Receptor mechanisms | Intracellular | Binding sites
Journal Article
Nature Reviews Drug Discovery, ISSN 1474-1776, 12/2018, Volume 18, Issue 1, pp. 59 - 82
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 12/2018, Volume 115, Issue 50, p. 12733
The human proteome contains 826 G protein-coupled receptors (GPCR), which control a wide array of key physiological functions, making them important drug... 
Physiological aspects | Nuclear magnetic resonance spectroscopy | Adenosine | Methods
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 07/2015, Volume 137, Issue 47, pp. 14877 - 14886
We report a magic angle spinning (MAS) NMR structure of the drug-resistant S31N mutation of M218-60 from Influenza A. The protein was dispersed in... 
Protein Conformation | Lipid Bilayers | Viral Matrix Proteins - chemistry | Dimerization | Molecular mechanics | Research | Structure | Analysis | Influenza | Analytical chemistry | Chemical Sciences
Journal Article
Structure (London, England : 1993), ISSN 0969-2126, 12/2016, Volume 24, Issue 12, pp. 2190 - 2197
Fluorine-19 nuclear magnetic resonance (NMR) was used to study conformational equilibria at the intracellular tips of helices VI and VII in a variant β... 
Protein Structure, Secondary | Signal Transduction | Humans | Models, Molecular | Nuclear Magnetic Resonance, Biomolecular | Crystallography, X-Ray | Muramidase - metabolism | Binding Sites | Arrestin - metabolism | Receptors, Adrenergic, beta-2 - metabolism | Receptors, Adrenergic, beta-2 - chemistry
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 08/2010, Volume 132, Issue 32, pp. 10958 - 10960
The tetrameric M2 proton channel from influenza A virus conducts protons at low pH and is inhibited by aminoadamantyl drugs such as amantadine and rimantadine.... 
Journal Article
Journal of biomolecular NMR, ISSN 0925-2738, 08/2019, pp. 1 - 10
Journal Article
Cell, ISSN 0092-8674, 01/2018, Volume 172, Issue 1-2, pp. 68 - 80.e12
Signaling across cellular membranes, the 826 human G protein-coupled receptors (GPCRs) govern a wide range of vital physiological processes, making GPCRs... 
G protein-coupled receptor | NMR | signaling | GPCR | membrane protein | nuclear magnetic resonance | allosteric modulation
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 07/2018, Volume 140, Issue 26, pp. 8228 - 8235
Tryptophan indole 15 N– 1 H signals are well separated in nuclear magnetic resonance (NMR) spectra of proteins. Assignment of the indole 15 N– 1 H signals... 
Journal Article
Protein Science, ISSN 0961-8368, 01/2016, Volume 25, Issue 1, pp. 46 - 55
Journal Article
by Gatsonis, Constantine A and Aberle, Denise R and Berg, Christine D and Black, William C and Church, Timothy R and Fagerstrom, Richard M and Galen, Barbara and Gareen, Ilana F and Goldin, Jonathan and Gohagan, John K and Hillman, Bruce and Jaffe, Carl and Kramer, Barnett S and Lynch, David and Marcus, Pamela M and Schnall, Mitchell and Sullivan, Daniel C and Sullivan, Dorothy and Zylak, Carl J and Cagnon, Christopher and Cody, Dianna and Fletcher, Glenn and Flynn, Michael J and Judy, Philip F and Kruger, Randell and Larke, Frederick J and McNitt-Gray, Michael and Payne, Thomas and Anthony Seibert, J and Wu, Xizeng and Abbott, Gerald and Amorosa, Judith K and Barr, Richard G and Boiselle, Phillip M and Chiles, Caroline and Clark, Robert and Coppage, Lynn and Falk, Robert and Fishman, Elliot K and Gemmel, David and Goldin, Jonathan G and Goodman, Eric and Hart, Eric M and Hazelton, Todd and Johnson, Elizabeth and Kazerooni, Ella and McComb, Barbara and McLennan, Geoffrey and Munden, Reginald F and Ravenel, James and Sullivan, Michael and Swensen, Stephen J and Torigian, Drew A and Vydareny, Kay H and Worrell, John A and Balkin, Peter and Fouad, Mona and Freedman, Matthew T and Garg, Kavita and Gelmann, Edward P and Gierada, David S and Hocking, William and Inampudi, Subbarao and Isaacs, Claudine and Kvale, Paul and Mann, Howard and Manor, William and Nath, Hrudaya and Reding, Douglas and Spizarny, David L and Strollo, Diane C and Waltz, John and Chen, Mei-Hsiu and Duan, Fenghai and Izmirilian, Grant and Pinsky, Paul and Prorok, Philip C and Miller, Anthony B and Edelman, Martin J and Evans, William K and Fontana, Robert S and Machtay, Mitchell and Clark, Kenneth W and Clingan, Kathy L and Ford, Melissa B and Márquez, Guillermo and Moore, Steven M and Ohan, Peter and Payne, Thomas J and Peace, Steven and Rosenbaum, Jennifer L and Barr, Richard and Black, William and Torigian, Drew and Vydareny, Kay and Worrell, John and Young, Robert C and Alberts, David and DeMets, David and Greenwald, Peter and ... and Natl Lung Screening Trial Res Team and National Lung Screening Trial Research Team
Radiology, ISSN 0033-8419, 01/2011, Volume 258, Issue 1, pp. 243 - 253
Journal Article