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Neuron, ISSN 0896-6273, 01/2013, Volume 77, Issue 1, pp. 58 - 69
Journal Article
DEVELOPMENT, ISSN 0950-1991, 09/2019, Volume 146, Issue 17, p. dev177188
The development of therapeutic interventions for hearing loss requires fundamental knowledge about the signaling pathways controlling tissue development as... 
OTIC PLACODE | SENSORY HAIR-CELLS | Hair cells | DEVELOPMENTAL BIOLOGY | Inner ear | Regeneration | VESTIBULAR FUNCTION | IN-VITRO | Organoids | HUMAN BRAIN-DEVELOPMENT | Stem cells | EMBRYONIC STEM-CELLS | MOUSE MODEL | GENE-THERAPY | MAMMALIAN COCHLEA | SUPPORTING CELLS
Journal Article
Nature Communications, ISSN 2041-1723, 06/2017, Volume 8, Issue 1, p. 15790
We recently developed base editing, a genome-editing approach that enables the programmable conversion of one base pair into another without double-stranded... 
MULTIDISCIPLINARY SCIENCES
Journal Article
Journal Article
by Forrest, Alistair R. R and Kawaji, Hideya and Rehli, Michael and Baillie, J. Kenneth and de Hoon, Michiel J. L and Haberle, Vanja and Lassmann, Timo and Kulakovskiy, Ivan V and Lizio, Marina and Itoh, Masayoshi and Andersson, Robin and Mungall, Christopher J and Meehan, Terrence F and Schmeier, Sebastian and Bertin, Nicolas and Jørgensen, Mette and Dimont, Emmanuel and Arner, Erik and Schmidl, Christian and Schaefer, Ulf and Medvedeva, Yulia A and Plessy, Charles and Vitezic, Morana and Severin, Jessica and Semple, Colin A and Ishizu, Yuri and Young, Robert S and Francescatto, Margherita and Alam, Intikhab and Albanese, Davide and Altschuler, Gabriel M and Arakawa, Takahiro and Archer, John A. C and Arner, Peter and Babina, Magda and Rennie, Sarah and Balwierz, Piotr J and Beckhouse, Anthony G and Pradhan-Bhatt, Swati and Blake, Judith A and Blumenthal, Antje and Bodega, Beatrice and Bonetti, Alessano and Briggs, James and Brombacher, Frank and Burroughs, A. Maxwell and Califano, Anea and Cannistraci, Carlo V and Carbajo, Daniel and Chen, Yun and Chierici, Marco and Ciani, Yari and Clevers, Hans C and Dalla, Emiliano and Davis, Carrie A and Detmar, Michael and Diehl, Alexander D and Dohi, Taeko and bløs, Finn and Edge, Albert S. B and Edinger, Matthias and Ekwall, Karl and Endoh, Mitsuhiro and Enomoto, Hideki and Fagiolini, Michela and Fairbairn, Lynsey and Fang, Hai and Farach-Carson, Mary C and Faulkner, Geoffrey J and Favorov, Alexander V and Fisher, Malcolm E and Frith, Martin C and Fujita, Rie and Fukuda, Shiro and Furlanello, Cesare and Furuno, Masaaki and Furusawa, Jun-ichi and Geijtenbeek, Teunis B and Gibson, Anew P and Gingeras, Thomas and Goldowitz, Daniel and Gough, Julian and Guhl, Sven and Guler, Reto and Gustincich, Stefano and Ha, Thomas J and Hamaguchi, Masahide and Hara, Mitsuko and Harbers, Matthias and Harshbarger, Jayson and Hasegawa, Akira and Hasegawa, Yuki and Hashimoto, Takehiro and Herlyn, Meenhard and Hitchens, Kelly J and Ho Sui, Shannan J and Hofmann, Oliver M and Hoof, Ilka and Hori, Fumi and Huminiecki, Lukasz and ... and FANTOM Consortium and RIKEN PMI CLST DGT and FANTOM Consortium and the RIKEN PMI and CLST (DGT) and The FANTOM Consortium and the RIKEN PMI and CLST (DGT)
Nature, ISSN 0028-0836, 2014, Volume 507, Issue 7493, pp. 462 - +
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1 - 10
Programmable nucleases can introduce precise changes to genomic DNA through homology-directed repair (HDR). Unfortunately, HDR is largely restricted to mitotic... 
CRISPR-CAS NUCLEASES | HAIR-CELLS | PROGENITORS | STEM-CELLS | OFF-TARGET | DNA CLEAVAGE | MULTIDISCIPLINARY SCIENCES | NEONATAL MICE | MAMMALIAN COCHLEA | WNT | GENOMIC DNA | Phosphorylation | Wnt protein | Mitosis | Editing | Homology | Injection | Ribonucleic acid--RNA | DNA repair | Inner ear | Proteins | β-catenin | Signaling | Cochlea | Stochasticity | Mutation | Nuclease | Deoxyribonucleic acid--DNA
Journal Article
by Andersson, Robin and Gebhard, Claudia and Miguel-Escalada, Irene and Hoof, Ilka and Bornholdt, Jette and Boyd, Mette and Chen, Yun and Zhao, Xiaobei and Schmidl, Christian and Suzuki, Takahiro and Ntini, Evgenia and Arner, Erik and Valen, Eivind and Li, Kang and Schwarzfischer, Lucia and Glatz, Dagmar and Raithel, Johanna and Lilje, Berit and Rapin, Nicolas and Bagger, Frederik Otzen and Jørgensen, Mette and Andersen, Peter Refsing and Bertin, Nicolas and Rackham, Owen and Burroughs, A. Maxwell and Baillie, J. Kenneth and Ishizu, Yuri and Shimizu, Yuri and Furuhata, Erina and Maeda, Shiori and Negishi, Yutaka and Mungall, Christopher J and Meehan, Terrence F and Lassmann, Timo and Itoh, Masayoshi and Kawaji, Hideya and Kondo, Naoto and Kawai, Jun and Lennartsson, Aneas and Daub, Carsten O and Heutink, Peter and Hume, David A and Jensen, Torben Heick and Suzuki, Harukazu and Hayashizaki, Yoshihide and Müller, Ferenc and Forrest, Alistair R. R and Carninci, Piero and Rehli, Michael and Sandelin, Albin and de Hoon, Michiel J. L and Haberle, Vanja and Kulakovskiy, Ivan V and Lizio, Marina and Mungall, Christoher J and Schmeier, Sebastian and Dimont, Emmanuel and Schmid, Christian and Schaefer, Ulf and Medvedeva, Yulia A and Plessy, Charles and Vitezic, Morana and Severin, James and Semple, Colin A and Young, Robert S and Francescatto, Margherita and Alam, Intikhab and Albanese, Davide and Altschuler, Gabriel M and Arakawa, Takahiro and Archer, John A. C and Arner, Peter and Babina, Magda and Rennie, Sarah and Balwierz, Piotr J and Beckhouse, Anthony G and Pradhan-Bhatt, Swati and Blake, Judith A and Blumenthal, Antje and Bodega, Beatrice and Bonetti, Alessano and Briggs, James and Brombacher, Frank and Califano, Anea and Cannistracti, Carlo V and Carbajo, Daniel and Chierici, Marco and Ciani, Yari and Clevers, Hans C and Dalla, Emiliano and Davis, Carrie A and Detmar, Michael and Diehl, Alexander D and Dohi, Taeko and bløs, Finn and Edge, Albert S. B and Edinger, Matthias and Ekwall, Karl and Endoh, Mitsuhiro and Enomoto, Hideki and ... and FANTOM Consortium and The FANTOM Consortium
Nature, ISSN 0028-0836, 2014, Volume 507, Issue 7493, pp. 455 - 461
Journal Article