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Journal Article
FASEB Journal, ISSN 0892-6638, 02/2011, Volume 25, Issue 2, pp. 703 - 713
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e61244
Soluble Epoxide Hydrolase (sEH) is a key enzyme in the metabolism and termination of action of epoxyeicosatrienoic acids, derivatives of arachidonic acid,... 
INHIBITION | HYPERPOLARIZING FACTOR | MULTIDISCIPLINARY SCIENCES | EPOXYGENASE | VASODILATION | SEX-DIFFERENCES | DYSFUNCTION | EPOXYEICOSATRIENOIC ACIDS | BRAIN | NEUROPROTECTION | EPOXYEICOSANOIDS | Cerebral Cortex - enzymology | Gene Expression | Vasodilator Agents - pharmacology | Corpus Striatum - physiopathology | Acetylcholine - pharmacology | Epoxide Hydrolases - blood | Humans | Endothelium, Vascular - physiopathology | Endothelium, Vascular - drug effects | Male | Mice, Transgenic | Brain Ischemia - physiopathology | Endothelium, Vascular - enzymology | Vasodilation | Cerebral Cortex - physiopathology | Epoxide Hydrolases - genetics | Brain Ischemia - enzymology | Animals | Sex Factors | Corpus Striatum - drug effects | Female | Mice | Cerebral Cortex - drug effects | Corpus Striatum - enzymology | Enzymes | Unsaturated fatty acids | Ischemia | Dilatation | Blood vessels | Hydrolases | Acetylcholine | Genetic engineering | Comparative analysis | Risk factors | Endothelium | Occlusion | Brain | Sex | Males | Arachidonic acid | Epoxide hydrolase | Cerebrovascular system | Cerebral blood flow | Rodents | Neostriatum | Injuries | Stroke | Transgenic mice | Sex differences | Metabolism | Acids | Perfusion | Skull | Circulatory system | Staphylococcal enterotoxin H | Females | Laboratory animals | Veins & arteries
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 06/2009, Volume 329, Issue 3, pp. 908 - 918
Journal Article
Journal Article
American journal of physiology. Endocrinology and metabolism, ISSN 0193-1849, 01/2015, Volume 308, Issue 2, pp. E97 - E110
Cytochrome P-450 epoxygenase-derived epoxyeicosatrienoic acids (EETs) exert diverse biological activities, which include potent vasodilatory,... 
CYP2J2 | Oxidative stress | Inflammation | Nonalcoholic fatty liver disease | Palmitic acid | EETs | CELLS | ACTIVATION | PHYSIOLOGY | palmitic acid | DIABETES-MELLITUS | PATHOGENESIS | nonalcoholic fatty liver disease | inflammation | INSULIN-RESISTANCE | ENDOCRINOLOGY & METABOLISM | MURINE STEATOHEPATITIS | DYSFUNCTION | NF-KAPPA-B | oxidative stress | Palmitic Acid - metabolism | Catalase - blood | Humans | Oxidative Stress - physiology | Cytochrome P-450 Enzyme System - metabolism | Superoxide Dismutase - blood | Male | NF-kappa B - metabolism | Alanine Transaminase - blood | 8,11,14-Eicosatrienoic Acid - metabolism | RNA - genetics | 8,11,14-Eicosatrienoic Acid - analogs & derivatives | Diet, High-Fat | Non-alcoholic Fatty Liver Disease - enzymology | Cytokines - blood | Disease Models, Animal | Non-alcoholic Fatty Liver Disease - genetics | Glutathione Peroxidase - blood | Mice, Inbred C57BL | Oxidative Stress - genetics | Mice, Transgenic | Non-alcoholic Fatty Liver Disease - metabolism | RNA - chemistry | Reverse Transcriptase Polymerase Chain Reaction | Hep G2 Cells | Animals | Aspartate Aminotransferases - blood | Triglycerides - blood | Cytochrome P-450 Enzyme System - genetics | Signal Transduction - physiology | Mice | Proteins | Fatty liver | Genetic aspects | Models | Gene expression | Identification and classification | Health aspects | Call for Papers
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2013, Volume 8, Issue 9, p. e75107
The epoxygenase CYP2J2 has an emerging role in inflammation and vascular biology. The role of CYP2J2 in phagocytosis is not known and its regulation in human... 
LISTERIA-MONOCYTOGENES | CYTOCHROME-P450 | SMOOTH-MUSCLE | IN-VITRO | METABOLITES | MULTIDISCIPLINARY SCIENCES | ULCERATIVE-COLITIS | RECEPTOR | INHIBITORS | ACUTE-INFLAMMATION | EXPRESSION | Crohn Disease - genetics | Antigens, CD - biosynthesis | Humans | Crohn Disease - metabolism | Male | 8,11,14-Eicosatrienoic Acid - metabolism | Antigens, CD - genetics | 8,11,14-Eicosatrienoic Acid - analogs & derivatives | CD11b Antigen - genetics | Escherichia coli - metabolism | Monocytes - pathology | Enzyme Induction - drug effects | Crohn Disease - microbiology | Female | Macrophages - microbiology | Cell Line | Monocytes - microbiology | Antigens, Differentiation, Myelomonocytic - biosynthesis | Macrophages - pathology | Antigens, Differentiation, Myelomonocytic - genetics | Macrophages - enzymology | Monocytes - enzymology | Crohn Disease - pathology | Lipopolysaccharides - pharmacology | Cytochrome P-450 Enzyme System - biosynthesis | Cytochrome P-450 Enzyme System - genetics | Phagocytosis | CD11b Antigen - biosynthesis | Medical research | Unsaturated fatty acids | Anti-inflammatory drugs | RNA | Tumor necrosis factor | Escherichia coli | Cytochrome P-450 | Medicine, Experimental | Crohn's disease | Inflammation | Arachidonic acid | Macrophages | Basic Medicine | Medical and Health Sciences | Microbiology in the medical area | Mikrobiologi inom det medicinska området | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2016, Volume 113, Issue 23, p. E3240
  Resolution of inflammation has emerged as an active process in immunobiology, with cells of the mononuclear phagocyte system being critical in mediating... 
Rodents | Medical treatment | T cell receptors | Apoptosis
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 10, p. e26591
Background: Arachidonic acid is metabolized through three major metabolic pathways, the cyclooxygenase, lipoxygenase and CYP450 enzyme systems. Unlike... 
CYP2J2 | GAMMA | CYTOCHROME-P450 | IN-VITRO | ACID | PROLIFERATOR-ACTIVATED RECEPTORS | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | EXPRESSION | KAPPA-B ACTIVITY | LAMINAR-FLOW | Cytochrome P-450 CYP2C8 | Immunomodulation | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Cytochrome P-450 Enzyme System - metabolism | Inflammation - immunology | Monocytes - immunology | Aryl Hydrocarbon Hydroxylases - metabolism | Macrophages - enzymology | Monocytes - enzymology | Transfection | HEK293 Cells | Cytochrome P-450 Enzyme System - genetics | Ligands | Gene Expression Regulation, Enzymologic - immunology | PPAR alpha - metabolism | Inflammation - enzymology | Macrophages - immunology | COX-2 inhibitors | Superoxide | RNA | Macrophages | Tumor necrosis factor | Cytochrome P-450 | Cytochrome | Heart | Health sciences | Superoxide dismutase | Smooth muscle | Cardiovascular disease | mRNA | Activation | Arachidonic acid | Modulators | Cell adhesion & migration | Prostaglandin endoperoxide synthase | Interleukin 4 | Cell activation | Anions | Pathways | Rodents | Inhibition | Growth factors | Hypertension | Wound healing | Cloning | Environmental health | Inflammation | Tumor necrosis factor-α | Gene expression | Endothelium | Monocytes | Acids | Coronary vessels | Metabolic pathways | Peroxisome proliferator-activated receptors | Cyclooxygenase-2 | Lipoxygenase
Journal Article
Heart, ISSN 1355-6037, 06/2017, Volume 103, Issue Suppl 5, pp. A108 - A109
IntroductionAspirin acts as an anti-thrombotic drug by inhibiting platelet cyclooxygenase-1 (COX-1) and blocking the production of thromboxane A2, but it also... 
Journal Article