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1. Full Text Beyond GWASs: Illuminating the Dark Road from Association to Function
by Edwards, Stacey L and Beesley, Jonathan and French, Juliet D and Dunning, Alison M
American journal of human genetics, ISSN 0002-9297, 11/2013, Volume 93, Issue 5, pp. 779 - 797
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Epigenesis, Genetic | Humans | Risk Factors | Computational Biology | Chromosome Mapping | Genetic Loci | RNA, Untranslated - genetics | Phenotype | Animals | Neoplasms - genetics | Polymorphism, Single Nucleotide | Neoplasms - pathology | Genetic variation | Genome-wide association studies | Research | Biological variation | Genes | Epigenetics | Genomes | Ribonucleic acid--RNA | Epidemiology | Bioinformatics | Index Medicus | Review
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2. Full Text Five endometrial cancer risk loci identified through genome-wide association analysis
by Cheng, Timothy H.T and Thompson, Deborah J and O'Mara, Tracy A and Painter, Jodie N and Glubb, Dylan M and Flach, Susanne and Lewis, Annabelle and French, Juliet D and Freeman-Mills, Luke and Church, David and Gorman, Maggie and Martin, Lynn and Hodgson, Shirley and MWebb, Penelope and Attia, John and Holliday, Elizabeth G and McEvoy, Mark and Scott, Rodney J and KHenders, Anjali and Martin, Nicholas G and Montgomery, Grant W and Nyholt, Dale R and Ahmed, Shahana and Healey, Catherine S and Shah, Mitul and Dennis, Joe and Fasching, Peter A and Beckmann, Matthias W and Hein, Alexander and Ekici, Arif B and Hall, Per and Czene, Kamila and Darabi, Hatef and Li, Jingmei and Dörk, Thilo and Dürst, Matthias and Hillemanns, Peter and Runnebaum, Ingo and Amant, Frederic and Schrauwen, Stefanie and Zhao, Hui and Lambrechts, Diether and Depreeuw, Jeroen and Dowdy, Sean C and Goode, Ellen L and Fridley, Brooke L and Winham, Stacey J and NjØlstad, Tormund S and Salvesen, Helga B and Trovik, Jone and Werner, Henrica M.J and Ashton, Katie and Otton, Geoffrey and Proietto, Tony and Liu, Tao and Mints, Miriam and Tham, Emma and Li, Mulin Jun and Yip, Shun H and Wang, Junwen and KBolla, Manjeet and Michailidou, Kyriaki and Wang, Qin and Tyrer, Jonathan P and Dunlop, Malcolm and Houlston, Richard and Palles, Claire and Hopper, John L and Peto, Julian and Swerdlow, Anthony J and Burwinkel, Barbara and Brenner, Hermann and Meindl, Alfons and Brauch, Hiltrud and Lindblom, Annika and Chang-Claude, Jenny and Couch, Fergus J and Giles, Graham G and Kristensen, Vessela N and Cox, Angela and MCunningham, Julie and Pharoah, Paul D.P and Dunning, Alison M and Edwards, Stacey L and Easton, Douglas F and Tomlinson, Ian and Spurdle, Amanda B and RENDOCAS and RENDOCAS CHIBCHA Consortium and AOCS Group and Australian Natl Endometrial Canc S and Natl Study Endometrial Canc Geneti and Australian National Endometrial Cancer Study Group (ANECS) and National Study of Endometrial Cancer Genetics Group (NSECG) and CHIBCHA Consortium and The Australian National Endometrial Cancer Study Group (ANECS)
Nature genetics, ISSN 1061-4036, 06/2016, Volume 48, Issue 6, pp. 667 - 674
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Promoter Regions, Genetic | Genetic Predisposition to Disease | Genome-Wide Association Study | Endometrial Neoplasms - genetics | Humans | Female | Chromosomes, Human, Pair 8 | Polymorphism, Single Nucleotide | Genome-wide association studies | Research | Endometrial cancer | Gene expression | Analysis | Risk factors | Medical research | Biomedical research | Funding | Genomes | Epidemiology | Ovarian cancer | Proteins | Studies | Confidence intervals | Hormone replacement therapy | Reproductive system | Health risk assessment | Index Medicus | Medicin och hälsovetenskap
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3. Full Text Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation
by Ghoussaini, Maya and French, Juliet D and Michailidou, Kyriaki and Nord, Silje and Beesley, Jonathan and Canisus, Sander and Hillman, Kristine M and Kaufmann, Susanne and Sivakumaran, Haran and Moradi Marjaneh, Mahdi and Lee, Jason S and Dennis, Joe and Bolla, Manjeet K and Wang, Qin and Dicks, Ed and Milne, Roger L and Hopper, John L and Southey, Melissa C and Schmidt, Marjanka K and Broeks, Annegien and Muir, Kenneth and Lophatananon, Artitaya and Fasching, Peter A and Beckmann, Matthias W and Fletcher, Olivia and Johnson, Nichola and Sawyer, Elinor J and Tomlinson, Ian and Burwinkel, Barbara and Marme, Frederik and Guénel, Pascal and Truong, Thérèse and Bojesen, Stig E and Flyger, Henrik and Benitez, Javier and González-Neira, Anna and Alonso, M. Rosario and Pita, Guillermo and Neuhausen, Susan L and Anton-Culver, Hoda and Brenner, Hermann and Arndt, Volker and Meindl, Alfons and Schmutzler, Rita K and Brauch, Hiltrud and Hamann, Ute and Tessier, Daniel C and Vincent, Daniel and Nevanlinna, Heli and Khan, Sofia and Matsuo, Keitaro and Ito, Hidemi and Dörk, Thilo and Bogdanova, Natalia V and Lindblom, Annika and Margolin, Sara and Mannermaa, Arto and Kosma, Veli-Matti and Wu, Anna H and Van Den Berg, David and Lambrechts, Diether and Floris, Giuseppe and Chang-Claude, Jenny and Rudolph, Anja and Radice, Paolo and Barile, Monica and Couch, Fergus J and Hallberg, Emily and Giles, Graham G and Haiman, Christopher A and Le Marchand, Loic and Goldberg, Mark S and Teo, Soo H and Yip, Cheng Har and Borresen-Dale, Anne-Lise and Zheng, Wei and Cai, Qiuyin and Winqvist, Robert and Pylkäs, Katri and Andrulis, Irene L and Devilee, Peter and Tollenaar, Rob A.E.M and García-Closas, Montserrat and Figueroa, Jonine and Hall, Per and Czene, Kamila and Brand, Judith S and Darabi, Hatef and Eriksson, Mikael and Hooning, Maartje J and Koppert, Linetta B and Li, Jingmei and Shu, Xiao-Ou and Zheng, Ying and Cox, Angela and Cross, Simon S and Shah, Mitul and Rhenius, Valerie and Choi, Ji-Yeob and Kang, Daehee and ... and kConFab/AOCS Investigators and NBCS Collaborators and kConFab AOCS
American journal of human genetics, ISSN 0002-9297, 10/2016, Volume 99, Issue 4, pp. 903 - 911
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fibroblast Growth Factor 10 - metabolism | Genetic Predisposition to Disease - genetics | Receptors, Estrogen - metabolism | Receptor, Fibroblast Growth Factor, Type 2 - metabolism | Humans | Promoter Regions, Genetic - genetics | Case-Control Studies | Breast Neoplasms - metabolism | Haplotypes - genetics | Breast Neoplasms - genetics | Alleles | Cell Line, Tumor | Polymorphism, Single Nucleotide - genetics | Enhancer Elements, Genetic - genetics | Fibroblast Growth Factor 10 - genetics | Chromosomes, Human, Pair 5 - genetics | Quantitative Trait Loci - genetics | Receptors | Genetic variation | Estrogen | Disease susceptibility | Genetic aspects | Breast cancer | Genetic regulation | Health aspects | Proteins | Genetics | Genomes | Gene expression | Index Medicus | Report | Medicin och hälsovetenskap
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4. Full Text Functional Variants at the 11q13 Risk Locus for Breast Cancer Regulate Cyclin D1 Expression through Long-Range Enhancers
by French, Juliet D and Ghoussaini, Maya and Edwards, Stacey L and Meyer, Kerstin B and Michailidou, Kyriaki and Ahmed, Shahana and Khan, Sofia and Maranian, Mel J and O’Reilly, Martin and Hillman, Kristine M and Betts, Joshua A and Carroll, Thomas and Bailey, Peter J and Dicks, Ed and Beesley, Jonathan and Tyrer, Jonathan and Maia, Ana-Teresa and Beck, Andrew and Knoblauch, Nicholas W and Chen, Constance and Kraft, Peter and Barnes, Daniel and González-Neira, Anna and Alonso, M. Rosario and Herrero, Daniel and Tessier, Daniel C and Vincent, Daniel and Bacot, Francois and Luccarini, Craig and Baynes, Caroline and Conroy, Don and Dennis, Joe and Bolla, Manjeet K and Wang, Qin and Hopper, John L and Southey, Melissa C and Schmidt, Marjanka K and Broeks, Annegien and Verhoef, Senno and Cornelissen, Sten and Muir, Kenneth and Lophatananon, Artitaya and Stewart-Brown, Sarah and Siriwanarangsan, Pornthep and Fasching, Peter A and Loehberg, Christian R and Ekici, Arif B and Beckmann, Matthias W and Peto, Julian and dos Santos Silva, Isabel and Johnson, Nichola and Aitken, Zoe and Sawyer, Elinor J and Tomlinson, Ian and Kerin, Michael J and Miller, Nicola and Marme, Frederik and Schneeweiss, Andreas and Sohn, Christof and Burwinkel, Barbara and Guénel, Pascal and Truong, Thérèse and Laurent-Puig, Pierre and Menegaux, Florence and Bojesen, Stig E and Nordestgaard, Børge G and Nielsen, Sune F and Flyger, Henrik and Milne, Roger L and Zamora, M. Pilar and Arias Perez, Jose Ignacio and Benitez, Javier and Anton-Culver, Hoda and Brenner, Hermann and Müller, Heiko and Arndt, Volker and Stegmaier, Christa and Meindl, Alfons and Lichtner, Peter and Schmutzler, Rita K and Engel, Christoph and Brauch, Hiltrud and Hamann, Ute and Justenhoven, Christina and Aaltonen, Kirsimari and Heikkilä, Päivi and Aittomäki, Kristiina and Blomqvist, Carl and Matsuo, Keitaro and Ito, Hidemi and Iwata, Hiroji and Sueta, Aiko and Bogdanova, Natalia V and Antonenkova, Natalia N and Dörk, Thilo and Lindblom, Annika and Margolin, Sara and Mannermaa, Arto and Kataja, Vesa and Kosma, Veli-Matti and ... and kConFab Investigators and The GENICA Network and KConFab Investigators and GENICA Network
American journal of human genetics, ISSN 0002-9297, 04/2013, Volume 92, Issue 4, pp. 489 - 503
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | GATA3 Transcription Factor - genetics | Cyclin D1 - metabolism | RNA, Small Interfering - genetics | Luciferases - metabolism | ets-Domain Protein Elk-4 - genetics | Humans | Gene Expression Regulation, Neoplastic | ets-Domain Protein Elk-4 - metabolism | Promoter Regions, Genetic - genetics | Case-Control Studies | Chromatin Immunoprecipitation | GATA3 Transcription Factor - antagonists & inhibitors | Female | Electrophoretic Mobility Shift Assay | Binding Sites | GATA3 Transcription Factor - metabolism | Real-Time Polymerase Chain Reaction | Chromatin - chemistry | RNA, Messenger - genetics | Silencer Elements, Transcriptional - genetics | Chromosomes, Human, Pair 11 - genetics | Reverse Transcriptase Polymerase Chain Reaction | ets-Domain Protein Elk-4 - antagonists & inhibitors | Breast Neoplasms - genetics | Cyclin D1 - genetics | Cell Line, Tumor | Polymorphism, Single Nucleotide - genetics | Enhancer Elements, Genetic - genetics | Chromatin - genetics | Health aspects | Breast cancer | Risk factors | Proteins | Signal transduction | Chromatin | Cyclin-dependent kinases | Gene expression | Binding sites | Index Medicus | Medicin och hälsovetenskap
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5. Full Text Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant
by Li, Jun and Woods, Susan L and Healey, Sue and Beesley, Jonathan and Chen, Xiaoqing and Lee, Jason S and Sivakumaran, Haran and Wayte, Nicci and Nones, Katia and Waterfall, Joshua J and Pearson, John and Patch, Anne-Marie and Senz, Janine and Ferreira, Manuel A and Kaurah, Pardeep and Mackenzie, Robertson and Heravi-Moussavi, Alireza and Hansford, Samantha and Lannagan, Tamsin R.M and Spurdle, Amanda B and Simpson, Peter T and da Silva, Leonard and Lakhani, Sunil R and Clouston, Andrew D and Bettington, Mark and Grimpen, Florian and Busuttil, Rita A and Di Costanzo, Natasha and Boussioutas, Alex and Jeanjean, Marie and Chong, George and Fabre, Aurélie and Olschwang, Sylviane and Faulkner, Geoffrey J and Bellos, Evangelos and Coin, Lachlan and Rioux, Kevin and Bathe, Oliver F and Wen, Xiaogang and Martin, Hilary C and Neklason, Deborah W and Davis, Sean R and Walker, Robert L and Calzone, Kathleen A and Avital, Itzhak and Heller, Theo and Koh, Christopher and Pineda, Marbin and Rudloff, Udo and Quezado, Martha and Pichurin, Pavel N and Hulick, Peter J and Weissman, Scott M and Newlin, Anna and Rubinstein, Wendy S and Sampson, Jone E and Hamman, Kelly and Goldgar, David and Poplawski, Nicola and Phillips, Kerry and Schofield, Lyn and Armstrong, Jacqueline and Kiraly-Borri, Cathy and Suthers, Graeme K and Huntsman, David G and Foulkes, William D and Carneiro, Fatima and Lindor, Noralane M and Edwards, Stacey L and French, Juliet D and Waddell, Nicola and Meltzer, Paul S and Worthley, Daniel L and Schrader, Kasmintan A and Chenevix-Trench, Georgia
American journal of human genetics, ISSN 0002-9297, 05/2016, Volume 98, Issue 5, pp. 830 - 842
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Adenomatous Polyposis Coli Protein - genetics | Stomach Neoplasms - genetics | Allelic Imbalance - genetics | Adenomatous Polyps - genetics | Humans | Exons - genetics | Male | DNA Copy Number Variations - genetics | Gastric Mucosa - metabolism | Loss of Heterozygosity | Promoter Regions, Genetic - genetics | Point Mutation - genetics | Exome - genetics | Pedigree | Female | Adenocarcinoma - genetics | Genetic Linkage - genetics | Adenomatous Polyposis Coli - genetics | High-Throughput Nucleotide Sequencing - methods | Genetic aspects | Gene mutations | Genetic variation | Health aspects | Stomach cancer | Heredity | Mutation | Genes | Index Medicus | Life Sciences | Biochemistry, Molecular Biology | Genomics
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