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Journal Article
Structure, ISSN 0969-2126, 10/2018, Volume 26, Issue 10, pp. 1303 - 1313.e4
Understanding gating principles of ion channels at high resolution is of great importance. Here we investigate the conformational transition from closed to... 
ryanodine receptor | ion channel gating | cryo-EM | lipid mimetic | calcium signaling | lipid nanodiscs | ACTIVATION | CA2+ RELEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | SARCOPLASMIC-RETICULUM | CELL BIOLOGY | CALCIUM-RELEASE CHANNEL | BIOPHYSICS | STRUCTURAL BASIS | PURIFICATION | MEMBRANE-PROTEINS | RECONSTITUTION | INSIGHTS | Physiological aspects | Membrane lipids | Protein binding
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 07/2016, Volume 12, Issue 7, pp. 490 - 496
Journal Article
Journal of Structural Biology, ISSN 1047-8477, 06/2012, Volume 178, Issue 3, pp. 311 - 318
Journal Article
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, ISSN 0005-2728, 07/2010, Volume 1797, pp. 10 - 10
Conference Proceeding
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, ISSN 0005-2728, 07/2010, Volume 1797, pp. 13 - 13
Conference Proceeding
2012, 2012, ISBN 9789400741379
Complex I is the first enzyme of the respiratory chain and plays a central role in cellular energy production. It has been implicated in many human... 
Biochemistry, general | Molecular Medicine | Biomedicine | Protein Structure | Membrane Biology | Biomedicine general | NADH: ubiquinone oxidoreductase (complex I) | T. thermophilus | X-ray crystallography | Respiratory chain | Electron transfer | Fe-S cluster | Proton translocation | Antiporters | E. coli
Book Chapter
Advances in Experimental Medicine and Biology, ISSN 0065-2598, 2017, Volume 981, pp. 179 - 204
Ryanodine receptors (RyRs) are large intracellular calcium release channels that play a crucial role in coupling excitation to contraction in both cardiac and... 
Calcium signalling | Ion channel gating | Cryo-EM | Ryanodine receptor
Journal Article