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Trends in Neurosciences, ISSN 0166-2236, 10/2019, Volume 42, Issue 10, pp. 663 - 666
Using single-cell RNA sequencing (RNA-seq), Kupari and coworkers ( . 2019) have generated a long sought-after molecular atlas of vagal afferents in the mouse.... 
transcriptomics | vagus nerve | single cell | autonomic nervous system
Journal Article
Endocrinology, ISSN 0013-7227, 10/2013, Volume 154, Issue 10, pp. 3552 - 3564
Journal Article
Endocrinology, ISSN 0013-7227, 12/2012, Volume 153, Issue 12, pp. 5782 - 5795
Journal Article
Journal Article
Endocrinology, ISSN 0013-7227, 01/2016, Volume 157, Issue 1, pp. 176 - 194
The 2 gut hormones glucagon-like peptide-1 (GLP-1) and peptide YY (PYY) are well known to be coexpressed, costored, and released together to coact in the... 
PROXIMAL SMALL-INTESTINE | ENERGY-BALANCE | PANCREATIC ENDOCRINE RESPONSES | GLUCAGON-LIKE PEPTIDE-1 | FOOD-INTAKE | ENDOCRINOLOGY & METABOLISM | GASTRIC-ACID SECRETION | CENTRAL-NERVOUS-SYSTEM | DEPENDENT INSULINOTROPIC POLYPEPTIDE | CELL-DIFFERENTIATION | BINDING-SITES | Intestinal Mucosa - metabolism | Peptide YY - metabolism | Rats, Wistar | Receptors, G-Protein-Coupled - metabolism | Enteroendocrine Cells - ultrastructure | Humans | Intestinal Mucosa - secretion | Neurotensin - secretion | Secretory Vesicles - metabolism | Ileum - metabolism | Male | Peptide Fragments - pharmacology | Recombinant Fusion Proteins - metabolism | Enteroendocrine Cells - secretion | Glucagon-Like Peptide 1 - genetics | Intestinal Mucosa - drug effects | Neurotensin - metabolism | Ileum - drug effects | Bombesin - pharmacology | Ileum - ultrastructure | Female | Enteroendocrine Cells - metabolism | Peptide YY - genetics | Genes, Reporter | Biomarkers - metabolism | Glucagon-Like Peptide 1 - metabolism | Intestinal Mucosa - ultrastructure | Secretory Vesicles - ultrastructure | Tissue Culture Techniques | Mice, Inbred C57BL | Mice, Transgenic | Ileum - secretion | Gene Expression Regulation - drug effects | Neurotensin - genetics | Secretory Vesicles - secretion | Animals | Secretory Vesicles - drug effects | Recombinant Fusion Proteins - genetics | Luminescent Proteins - genetics | Receptors, G-Protein-Coupled - genetics | Enteroendocrine Cells - drug effects | Luminescent Proteins - metabolism | Endokrinologi och diabetes | GASTRIC-ACID | SECRETION | Endocrinology and Diabetes
Journal Article
Endocrinology, ISSN 0013-7227, 11/2015, Volume 156, Issue 11, pp. 3909 - 3923
In the stomach, somatostatin (SST) acts as a general paracrine negative regulator of exocrine secretion of gastric acid and pepsinogen and endocrine secretion... 
PERFUSED RAT STOMACH | CALCIUM-SENSING RECEPTOR | GLUCAGON-LIKE PEPTIDE-1 | GROWTH-HORMONE | GHRELIN SECRETION | ENTEROENDOCRINE CELLS | ACID-SECRETION | ENDOCRINOLOGY & METABOLISM | ISLET AMYLOID POLYPEPTIDE | RELEASE-INHIBITING HORMONE | ENDOCRINE-CELLS | Peptide YY - metabolism | Receptors, G-Protein-Coupled - metabolism | Humans | Transcriptome | Male | Receptors, Muscarinic - metabolism | Receptors, Neuropeptide - metabolism | Islet Amyloid Polypeptide - genetics | Stomach - metabolism | Gastric Mucosa - metabolism | Receptors, Somatostatin - genetics | Glucagon-Like Peptide-1 Receptor - genetics | Glucagon-Like Peptide-1 Receptor - metabolism | In Situ Hybridization | Receptors, Adrenergic - genetics | Receptors, Somatostatin - metabolism | Peptide YY - genetics | Somatostatin - metabolism | Receptors, Muscarinic - genetics | Somatostatin - secretion | Somatostatin - genetics | Receptors, Adrenergic - metabolism | Cells, Cultured | Islet Amyloid Polypeptide - metabolism | Receptors, Neuropeptide - genetics | Mice, Transgenic | Gastric Mucosa - cytology | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Microscopy, Confocal | Animals | Stomach - cytology | Luminescent Proteins - genetics | Receptors, G-Protein-Coupled - genetics | Somatostatin-Secreting Cells - metabolism | Luminescent Proteins - metabolism
Journal Article
Gastroenterology, ISSN 0016-5085, 10/2018, Volume 155, Issue 4, pp. 1164 - 1176.e2
BACKGROUND & AIMS: Glucagon-like peptide 1 (GLP1) is produced by L cells in the intestine, and agonists of the GLP1 receptor are effective in the treatment of... 
Enteroendocrine Cells | Signal Transduction | Type 2 Diabetes | Mouse Model | STEM-CELLS | GLP-1 | MOUSE | YAP | PROLIFERATION | SPECIFICATION | GTPASES | YAP/TAZ | DIFFERENTIATION | GASTROENTEROLOGY & HEPATOLOGY | ENDOCRINE-CELLS | Ileum - metabolism | Glucagon-Like Peptide 1 - blood | Male | Organoids - secretion | Insulin - blood | Stem Cells - metabolism | Enteroendocrine Cells - secretion | Glucose Intolerance - blood | rho-Associated Kinases - antagonists & inhibitors | Glucose Intolerance - drug therapy | Ileum - drug effects | Time Factors | rho-Associated Kinases - metabolism | Glucose Intolerance - etiology | Diet, High-Fat | Organoids - metabolism | Enteroendocrine Cells - metabolism | Glucose Intolerance - physiopathology | Disease Models, Animal | Amides - pharmacology | Tissue Culture Techniques | Mice, Inbred C57BL | Insulin Resistance | Mice, Transgenic | Biomarkers - blood | Ileum - secretion | Hypoglycemic Agents - pharmacology | Blood Glucose - drug effects | Cell Lineage | Phenotype | Stem Cells - secretion | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | rho GTP-Binding Proteins - metabolism | Organoids - drug effects | Stem Cells - drug effects | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Blood Glucose - metabolism | Enteroendocrine Cells - drug effects | Glucose | Statistics | Analysis | Cells | Dextrose
Journal Article
Molecular Metabolism, ISSN 2212-8778, 06/2018, Volume 12, pp. 62 - 75
G protein-coupled receptors (GPCRs) act as transmembrane molecular sensors of neurotransmitters, hormones, nutrients, and metabolites. Because unmyelinated... 
GLP1R | G protein-coupled receptors | Gut hormones | Gut-brain axis | Vagal afferent nerves | NTSR1 | CHOLECYSTOKININ RECEPTORS | NERVE | FOOD-INTAKE | GHRELIN | C-FIBERS | GLUCAGON-LIKE PEPTIDE-1 | ENDOCRINOLOGY & METABOLISM | NEURONS | RAT NODOSE | DEPENDENT INSULINOTROPIC POLYPEPTIDE | BINDING-SITES
Journal Article