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Diabetes Care, ISSN 0149-5992, 09/2009, Volume 32, Issue 9, pp. 1663 - 1668
Journal Article
Physiology, ISSN 1548-9213, 12/2009, Volume 24, Issue 6, pp. 325 - 331
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 04/2007, Volume 356, Issue 15, pp. 1517 - 1526
The expression of interleukin-1–receptor antagonist is reduced in pancreatic islets in type 2 diabetes, and high glucose concentrations induce interleukin-1β... 
INSULIN | MEDICINE, GENERAL & INTERNAL | HUMAN PANCREATIC-ISLETS | OBESITY | GLUCOSE | BETA-CELL APOPTOSIS | DISEASE | MUSCLE | EXPRESSION | RECEPTOR ANTAGONIST | NIDDM | Recombinant Proteins - therapeutic use | Insulin-Secreting Cells - secretion | Glucose Transporter Type 4 - metabolism | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Male | Diabetes Mellitus, Type 2 - metabolism | RNA, Messenger - metabolism | Heat-Shock Proteins - genetics | Insulin Resistance - physiology | Interleukin-6 - blood | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Female | Interleukin 1 Receptor Antagonist Protein - pharmacology | Body Mass Index | Glucose Tolerance Test | Double-Blind Method | Glucose Transporter Type 4 - genetics | Heat-Shock Proteins - metabolism | C-Reactive Protein - secretion | Recombinant Proteins - pharmacology | Transcription Factors - genetics | Gene Expression Regulation - drug effects | Transcription Factors - metabolism | Interleukin 1 Receptor Antagonist Protein - therapeutic use | Insulin-Secreting Cells - drug effects | Interleukin 1 Receptor Antagonist Protein - adverse effects | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Receptors, Interleukin-1 - antagonists & inhibitors | Type 2 diabetes | Interleukin-1 | Research | Drug therapy | Pancreas | Diabetes | Apoptosis | Index Medicus | Abridged Index Medicus | Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2011, Volume 17, Issue 11, pp. 1481 - 1489
Journal Article
Journal of Immunology, ISSN 0022-1767, 01/2014, Volume 192, Issue 2, pp. 623 - 629
Chronic inflammation is known to promote metabolic dysregulation in obesity and type 2 diabetes. Although the precise origin of the unchecked inflammatory... 
IMMUNE-SYSTEM | INFLAMMATION | DISEASE | RESISTANCE | FAT | AKT | IMMUNOLOGY | DIET-INDUCED OBESITY | KEY PLAYERS | ADIPOSE-TISSUE | CUTTING EDGE | Tumor Necrosis Factor-alpha - metabolism | Antigens, CD - immunology | T-Lymphocytes, Regulatory - metabolism | Epithelial Cells - metabolism | TOR Serine-Threonine Kinases - metabolism | Obesity - immunology | Insulin - immunology | Interferon-gamma - metabolism | Antigens, CD - metabolism | T-Lymphocytes, Regulatory - immunology | Epithelium - immunology | Signal Transduction - immunology | Inflammation - metabolism | Tumor Necrosis Factor-alpha - immunology | Interleukin-10 - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Receptor, Insulin - immunology | Macrophages - immunology | Hyperinsulinism - metabolism | Intra-Abdominal Fat - immunology | Transforming Growth Factor beta - immunology | Epithelium - metabolism | Mice, Inbred C57BL | Apyrase - metabolism | Cells, Cultured | Apyrase - immunology | CTLA-4 Antigen - metabolism | Inflammation - immunology | CTLA-4 Antigen - immunology | Intra-Abdominal Fat - metabolism | Obesity - metabolism | TOR Serine-Threonine Kinases - immunology | Insulin - metabolism | Macrophages - metabolism | Animals | Hyperinsulinism - immunology | Proto-Oncogene Proteins c-akt - immunology | Epithelial Cells - immunology | Interferon-gamma - immunology | Interleukin-10 - antagonists & inhibitors | Receptor, Insulin - metabolism | Mice | Interleukin-10 - immunology | Transforming Growth Factor beta - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Endocrinology, ISSN 0013-7227, 12/2009, Volume 150, Issue 12, pp. 5218 - 5229
Journal Article
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 10/2008, Volume 93, Issue 10, pp. 4065 - 4074
Context: Elevated glucose levels impair islet function and survival, and it has been proposed that intraislet expression of IL-1β contributes to glucotoxicity.... 
LASER CAPTURE MICRODISSECTION | HUMAN PANCREATIC-ISLETS | PSAMMOMYS-OBESUS | INSULIN-SECRETION | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | DEATH | INDUCTION | SMOOTH-MUSCLE CELLS | RECEPTOR ANTAGONIST | INFLAMMATORY MEDIATORS | Original
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2008, Volume 105, Issue 35, pp. 13163 - 13168
Journal Article
Diabetes, ISSN 0012-1797, 03/2003, Volume 52, Issue 3, pp. 741 - 750
Dipeptidyl Peptidase IV Inhibitor Treatment Stimulates β-Cell Survival and Islet Neogenesis in Streptozotocin-Induced Diabetic Rats J. Andrew Pospisilik 1 ,... 
IR, immunoreactive | GIP, glucose-dependent insulinotropic polypeptide | GLP-1, glucagon-like peptide-1 | PDX-1, pancreatic-duodenum homeobox-1 | OGTT, oral glucose tolerance test | IDGTT, intraduodenal glucose tolerance test | DP IV, dipeptidyl peptidase IV | IN-VITRO | GLUCAGON-LIKE PEPTIDE-1 | ENDOCRINOLOGY & METABOLISM | PANCREAS | DEGRADATION | CD26 | DEPENDENT INSULINOTROPIC POLYPEPTIDE | FATTY RATS | SECRETION | LONG-TERM TREATMENT | IMPROVED GLUCOSE-TOLERANCE | Immunohistochemistry | Diabetes Mellitus, Experimental - drug therapy | Glucagon-Like Peptide 1 | Insulin - analysis | Liver - enzymology | Protein Precursors - blood | Rats, Wistar | Cell Count | Dipeptidyl Peptidase 4 - blood | Glucagon - administration & dosage | Islets of Langerhans - chemistry | Male | Insulin - blood | Glucagon - blood | Glucagon-Like Peptides | Islets of Langerhans - metabolism | Phosphoenolpyruvate Carboxykinase (GTP) - analysis | Lipids - blood | Peptide Fragments - blood | Weight Gain - drug effects | Protease Inhibitors - therapeutic use | Insulin Secretion | Diabetes Mellitus, Experimental - physiopathology | Cell Survival - drug effects | Glucose Tolerance Test | Blood Glucose - analysis | Islets of Langerhans - pathology | Protein Precursors - administration & dosage | Peptide Fragments - administration & dosage | Rats | Cell Division - drug effects | Gastric Inhibitory Polypeptide - administration & dosage | Eating - drug effects | Insulin - metabolism | Animals | Cell Differentiation - drug effects | Diabetes Mellitus, Experimental - pathology | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article