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science & technology (39) 39
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genetics of eukaryotes. biological and molecular evolution (6) 6
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adaptor proteins, signal transducing - genetics (5) 5
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qt interval duration (4) 4
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analysis (3) 3
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1. Full Text Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function
by Hancock, Dana and Eijgelsheim, Mark and Wilk, Jemma and Gharib, Sina and Loehr, Laura and Marciante, Kristin and Franceschini, Nora and Durme, Y.M.T.A and Chen, T.H and Barr, Graham and Schabath, Matthew and Couper, David and Brusselle, Guy and Psaty, Bruce and Tikka-Kleemola, Päivi and Rotter, Jerome and Uitterlinden, Ané and Hofman, Albert and Punjabi, Naresh and Rivadeneira Ramirez, Fernando and Morrison, Alanna and Enright, Paul and North, Kari and Heckbert, Susan and Lumley, Thomas and Stricker, Bruno and O'Connor, George and London, Stephanie
Nature genetics, ISSN 1061-4036, 01/2010, Volume 42, Issue 1, pp. 45 - 52
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Spirometry | Genetic Predisposition to Disease - genetics | Meta-Analysis as Topic | Humans | Databases, Genetic | Male | Lung - physiopathology | Lung - physiology | Genome, Human - genetics | Forced Expiratory Volume | Vital Capacity | Lung Diseases - genetics | Female | Lung - metabolism | Lung Diseases - physiopathology | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Usage | United States | Mortality | Respiratory tract diseases | Development and progression | Genetic aspects | Research | Risk factors | Meta-analysis | Studies | Medical research | Lungs | Sample size | Disease | Respiratory diseases | Contracts | Smoking | Index Medicus
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2. Full Text Common variants at ten loci influence QT interval duration in the QTGEN Study
by Newton-Cheh, Christopher and Kors, Jan A and de Bakker, Paul I W and Witteman, Jacqueline C M and Estrada, Karol and Heckbert, Susan R and Uitterlinden, André G and Smith, Nicholas L and Eijgelsheim, Mark and Lumley, Thomas and Ch Stricker, Bruno H and O'Donnell, Christopher J and Rice, Kenneth M and Sotoodehnia, Nona and Larson, Martin G and Yin, Xiaoyan and Noseworthy, Peter A and Bis, Joshua C and Hofman, Albert and Marciante, Kristin and Rotter, Jerome I and Rivadeneira, Fernando and Psaty, Bruce M
Nature genetics, ISSN 1061-4036, 04/2009, Volume 41, Issue 4, pp. 399 - 406
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease - genetics | Meta-Analysis as Topic | Arrhythmias, Cardiac - chemically induced | KCNQ1 Potassium Channel - genetics | Humans | Risk Factors | Chromosome Mapping | Electroencephalography | ERG1 Potassium Channel | Ether-A-Go-Go Potassium Channels - genetics | Death, Sudden, Cardiac | Genetic Variation | Muscle Proteins - genetics | Adaptor Proteins, Signal Transducing - genetics | Polymorphism, Single Nucleotide - genetics | Adult | Aged | Sodium Channels - genetics | Genome, Human | Arrhythmias, Cardiac - genetics | NAV1.5 Voltage-Gated Sodium Channel | Potassium Channels, Voltage-Gated - genetics | Complications and side effects | Genetic variation | Cardiac arrest | Long QT syndrome | Genetic aspects | Research | Risk factors | Studies | Confidence intervals | Cardiac arrhythmia | Technological change | Quality control | Data base management | Kidney diseases | Neurological disorders | Family physicians | Index Medicus
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3. Full Text Proton Pump Inhibitors and Hypomagnesemia in the General Population: A Population-Based Cohort Study
by Kieboom, Brenda C.T., MD and Kiefte–de Jong, Jessica C., RD, PhD and Eijgelsheim, Mark, MD, PhD and Franco, Oscar H., MD, PhD and Kuipers, Ernst J., MD, PhD and Hofman, Albert, MD, PhD and Zietse, Robert, MD, PhD and Stricker, Bruno H., MMed, PhD and Hoorn, Ewout J., MD, PhD
American journal of kidney diseases, ISSN 0272-6386, 2015, Volume 66, Issue 5, pp. 775 - 782
Nephrology | histamine 2 receptor antagonist (H2RA) | diuretics | acid-suppressive medication | drug safety | hypomagnesemia | intestinal magnesium loss | Rotterdam Study | magnesium | proton pump inhibitor (PPI) | population-based cohort | Epidemiology | TRPM6 | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Multivariate Analysis | Prospective Studies | Cross-Sectional Studies | Sodium Potassium Chloride Symporter Inhibitors - therapeutic use | Diet - statistics & numerical data | Risk Factors | Water-Electrolyte Imbalance - epidemiology | Linear Models | Proton Pump Inhibitors - therapeutic use | Histamine H2 Antagonists - therapeutic use | Magnesium - blood | Cohort Studies | Index Medicus
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4. Full Text A genome-wide association study of acenocoumarol maintenance dosage
by Teichert, M and Eijgelsheim, M and Rivadeneira, F and Uitterlinden, A.G and Schaik, R.H. van and Hofman, A and Smet, P.A.G.M. de and Gelder, T. van and Visser, L.E and Stricker, B.H.C
Human molecular genetics, ISSN 0964-6906, 2009, Volume 18, Issue 19, pp. 3758 - 3768
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Cytochrome P-450 CYP2C9 | Genome-Wide Association Study | Prospective Studies | Anticoagulants - administration & dosage | Humans | Middle Aged | Aryl Hydrocarbon Hydroxylases - genetics | Drug Therapy | Male | Vitamin K Epoxide Reductases | Dose-Response Relationship, Drug | Acenocoumarol - administration & dosage | Aged, 80 and over | Female | Aged | Polymorphism, Single Nucleotide | Mixed Function Oxygenases - genetics | Index Medicus
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5. Full Text Pharmacogenetics of Drug-Induced QT Interval Prolongation: An Update
by Niemeijer, Maartje N and van den Berg, Marten E and Eijgelsheim, Mark and Rijnbeek, Peter R and Stricker, Bruno H
Drug safety, ISSN 0114-5916, 10/2015, Volume 38, Issue 10, pp. 855 - 867
Medicine & Public Health | Drug Safety and Pharmacovigilance | Pharmacology/Toxicology | Pharmacology & Pharmacy | Public, Environmental & Occupational Health | Toxicology | Life Sciences & Biomedicine | Science & Technology | Brugada Syndrome - genetics | Pharmacogenetics - methods | Animals | Drug-Related Side Effects and Adverse Reactions - genetics | Humans | Long QT Syndrome - genetics | Long QT Syndrome - chemically induced | Genetic Variation - genetics | Cardiac Conduction System Disease | Brugada Syndrome - chemically induced | Cytochrome | Cardiac arrhythmia | Enzymes | Research & development--R&D | Funding | Genes | Cardiovascular disease | Cultural differences | Studies | Heart rate | Prescription drugs | Electrocardiography | Long QT syndrome | Influence | Pharmaceutical industry | Product safety
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6. Full Text Normal values of corrected heart-rate variability in 10-second electrocardiograms for all ages
by Berg, Marten and Rijnbeek, Peter and Niemeijer, Maartje and Hofman, Albert and Herpen, G and Bots, Michiel and Hillege, Hans and Swenne, Cees and Eijgelsheim, M and Stricker, B.H and Kors, Jan
Frontiers in physiology, ISSN 1664-042X, 04/2018, Volume 9, Issue APR, pp. 424 - 424
Normal values | Electrocardiography | Adults | Heart-rate correction | Children | Elderly | Heart-rate variability | Life Sciences & Biomedicine | Physiology | Science & Technology | Physiological aspects | Heart beat | Cardiovascular diseases | Cardiac patients | Risk factors | heart-rate variability | normal values | heart-rate correction | children | adults | electrocardiography
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7. Full Text Short-term QT variability markers for the prediction of ventricular arrhythmias and sudden cardiac death: a systematic review
by Niemeijer, Maartje N and van den Berg, Marten E and Eijgelsheim, Mark and van Herpen, Gerard and Stricker, Bruno H and Kors, Jan A and Rijnbeek, Peter R
Heart (British Cardiac Society), ISSN 1355-6037, 12/2014, Volume 100, Issue 23, pp. 1831 - 1836
Arrhythmias | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Heart Rate | Predictive Value of Tests | Prognosis | Arrhythmias, Cardiac - mortality | Risk Assessment | Humans | Risk Factors | Death, Sudden, Cardiac - etiology | Arrhythmias, Cardiac - physiopathology | Time Factors | Electrocardiography | Arrhythmias, Cardiac - complications | Arrhythmias, Cardiac - diagnosis | Usage | Arrhythmia | Electrocardiogram | Cardiac arrest | Diagnosis | Research | Biological markers | Health aspects | Risk factors | Studies | Heart failure | Short term | Cardiac arrhythmia | Publications | Mortality | Cardiovascular disease | Full text | Product safety | Index Medicus | Abridged Index Medicus
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8. Full Text Declining incidence of sudden cardiac death from 1990–2010 in a general middle-aged and elderly population: The Rotterdam Study
by Niemeijer, Maartje N., MD and van den Berg, Marten E., MD and Leening, Maarten J.G., MD and Hofman, Albert, MD, PhD and Franco, Oscar H., MD, PhD and Deckers, Jaap W., MD, PhD and Heeringa, Jan, MD, PhD and Rijnbeek, Peter R., PhD and Stricker, Bruno H., MMed, PhD and Eijgelsheim, Mark, MD, PhD
Heart rhythm, ISSN 1547-5271, 2015, Volume 12, Issue 1, pp. 123 - 129
Cardiovascular | Mortality | Population-based study | Cardiovascular disease | Time trends | Sudden cardiac death | Epidemiology | Incidence | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Age Factors | Death, Sudden, Cardiac - epidemiology | Humans | Middle Aged | Netherlands - epidemiology | Risk Factors | Male | Time Factors | Sex Factors | Aged, 80 and over | Female | Aged | Seasons | Health Status | Heart | Cardiac arrest | Medical informatics | Index Medicus
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9. Full Text Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction
by Sotoodehnia, Nona and Isaacs, Aaron and de Bakker, Paul I. W and Doerr, Marcus and Newton-Cheh, Christopher and Nolte, Ilja M and van der Harst, Pim and Mueller, Martina and Eijgelsheim, Mark and Alonso, Alvaro and Hicks, Anew A and Padmanabhan, Sandosh and Hayward, Caroline and Smith, Albert Vernon and Polasek, Ozren and Giovannone, Steven and Fu, Jingyuan and Magnani, Jared W and Marciante, Kristin D and Pfeufer, Arne and Gharib, Sina A and Teumer, Alexander and Li, Man and Bis, Joshua C and Rivadeneira, Fernando and Aspelund, Thor and Koettgen, Anna and Johnson, Toby and Rice, Kenneth and Sie, Mark P. S and Wang, Ying A and Klopp, Norman and Fuchsberger, Christian and Wild, Sarah H and Mateo Leach, Irene and Estrada, Karol and Voelker, Uwe and Wright, Alan F and Asselbergs, Folkert W and Qu, Jiaxiang and Chakravarti, Aravinda and Sinner, Moritz F and Kors, Jan A and Petersmann, Astrid and Harris, Tamara B and Soliman, Elsayed Z and Munroe, Patricia B and Oostra, Ben A and Cupples, L. Aienne and Perz, Siegfried and de Boer, Rudolf A and Uitterlinden, Ane G and Voelzke, Henry and Spector, Timothy D and Liu, Fang-Yu and Boerwinkle, Eric and Dominiczak, Anna F and Rotter, Jerome I and van Herpen, Ge and Levy, Daniel and Wichmann, H-Erich and van Gilst, Wiek H and Witteman, Jacqueline C. M and Kroemer, Heyo K and Kao, W. H. Linda and Heckbert, Susan R and Meitinger, Thomas and Hofman, Albert and Campbell, Harry and Folsom, Aaron R and van Veldhuisen, Dirk J and Schwienbacher, Christine and O'Donnell, Christopher J and Volpato, Claudia Beu and Caulfield, Mark J and Connell, John M and Launer, Lenore and Lu, Xiaowen and Franke, Lude and Fehrmann, Rudolf S. N and Groen, Harry J. M and Weersma, Rinse K and van den Berg, Leonard H and Wijmenga, Cisca and Ophoff, Roel A and Navis, Gerjan and Snieder, Harold and Wilson, James F and Pramstaller, Peter P and Siscovick, David S and Wang, Thomas J and Gudnason, Vilmundur and van Duijn, Cornelia M and Felix, Stephan B and Fishman, Glenn I and Jamshidi, Yalda and Stricker, Bruno H. Ch and Samani, Nilesh J and Kaeaeb, Stefan and Arking, Dan E
Nature genetics, ISSN 1061-4036, 12/2010, Volume 42, Issue 12, pp. 1068 - U62
SYSTEM | PR INTERVAL | ELECTROCARDIOGRAM | DISEASE | GENE-EXPRESSION | RICH REPEAT PROTEIN | HEART-RATE | QT INTERVAL DURATION | TRANSCRIPTION FACTOR | GENOME-WIDE ASSOCIATION | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Animals, Newborn | Genome-Wide Association Study | Chromosomes, Human - genetics | Humans | Computational Biology | Genetic Loci - genetics | Mice, Transgenic | Animals | NAV1.8 Voltage-Gated Sodium Channel | Heart Conduction System - physiology | Electrocardiography | Myocytes, Cardiac - metabolism | Polymorphism, Single Nucleotide - genetics | Models, Animal | Mice | Sodium Channels - genetics | Heart failure | Care and treatment | Usage | Electrocardiogram | Physiological aspects | Genetic aspects | Diagnosis | Research | DNA binding proteins | Health aspects | Risk factors | Studies | Kinases | Index Medicus | ECG | quantitative trait | QRS interval | genome-wide association study
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