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by Gröbner, Susanne N and Worst, Barbara C and Weischenfeldt, Joachim and Buchhalter, Ivo and Kleinheinz, Kortine and Rudneva, Vasilisa A and Johann, Pascal D and Balasubramanian, Gnana Prakash and Segura-Wang, Maia and Brabetz, Sebastian and Bender, Sebastian and Hutter, Barbara and Sturm, Dominik and Pfaff, Elke and Hübschmann, Daniel and Zipprich, Gideon and Heinold, Michael and Eils, Jürgen and Lawerenz, Christian and Erkek, Serap and Lambo, Sander and Waszak, Sebastian and Blattmann, Claudia and Borkhardt, Arndt and Kuhlen, Michaela and Eggert, Angelika and Fulda, Simone and Gessler, Manfred and Wegert, Jenny and Kappler, Roland and Baumhoer, Daniel and Burdach, Stefan and Kirschner-Schwabe, Renate and Kontny, Udo and Kulozik, Andreas E and Lohmann, Dietmar and Hettmer, Simone and Eckert, Cornelia and Bielack, Stefan and Nathrath, Michaela and Niemeyer, Charlotte and Richter, Günther H and Schulte, Johannes and Siebert, Reiner and Westermann, Frank and Molenaar, Jan J and Vassal, Gilles and Witt, Hendrik and Burkhardt, Birgit and Kratz, Christian P and Witt, Olaf and van Tilburg, Cornelis M and Kramm, Christof M and Fleischhack, Gudrun and Dirksen, Uta and Rutkowski, Stefan and Frühwald, Michael and von Hoff, Katja and Wolf, Stephan and Klingebiel, Thomas and Koscielniak, Ewa and Landgraf, Pablo and Koster, Jan and Resnick, Adam C and Zhang, Jinghui and Liu, Yanling and Zhou, Xin and Waanders, Angela J and Zwijnenburg, Danny A and Raman, Pichai and Brors, Benedikt and Weber, Ursula D and Northcott, Paul A and Pajtler, Kristian W and Kool, Marcel and Piro, Rosario M and Korbel, Jan O and Schlesner, Matthias and Eils, Roland and Jones, David T. W and Lichter, Peter and Chavez, Lukas and Zapatka, Marc and Pfister, Stefan M and ICGC PedBrain-Seq Project ICGC and ICGC MMML-Seq Project and ICGC PedBrain-Seq Project
Nature (London), ISSN 1476-4687, 2018, Volume 555, Issue 7696, pp. 321 - 327
Journal Article
Nature communications, ISSN 2041-1723, 2019, Volume 10, Issue 1, pp. 368 - 13
... Woerner5, Birgit Kaiser4, Claudia Scherl7, Marlen Haderlein8, Kortine Kleinheinz9, Rainer Fietkau8, Heinrich Iro7, Roland Eils2,3,10,11, Arndt Hartmann1, Christoph... 
HEAD | FUSION | GENE | ALIGNMENT | NOR1 | MULTIDISCIPLINARY SCIENCES | MYB | EXPRESSION | CANCER | TUMORS | ORPHAN NUCLEAR RECEPTOR | Chromatin - metabolism | Translocation, Genetic | Multigene Family | Salivary Glands - pathology | Salivary Proteins and Peptides - genetics | Cell Proliferation | Receptors, Steroid - metabolism | Salivary Gland Neoplasms - genetics | Epigenesis, Genetic | Humans | Carcinoma, Acinar Cell - pathology | Gene Expression Regulation, Neoplastic | Male | Genetic Loci | DNA-Binding Proteins - metabolism | Carcinoma, Acinar Cell - metabolism | Receptors, Thyroid Hormone - genetics | Salivary Gland Neoplasms - metabolism | Female | Chromatin - chemistry | Acinar Cells - metabolism | Carcinoma, Acinar Cell - genetics | DNA-Binding Proteins - genetics | Salivary Proteins and Peptides - metabolism | Chromosomes, Human, Pair 4 - metabolism | Chromosomes, Human, Pair 9 - metabolism | Receptors, Thyroid Hormone - metabolism | Chromosomes, Human, Pair 4 - chemistry | Acinar Cells - pathology | Animals | Enhancer Elements, Genetic | Receptors, Steroid - genetics | Chromosomes, Human, Pair 9 - chemistry | Mice | Primary Cell Culture | Salivary Gland Neoplasms - pathology | Salivary Glands - metabolism | Cohort Studies | Binding | Cell proliferation | Chromatin | Transcription factors | Carcinoma | Salivary glands | Pathogenesis | Salivary gland | Chromosome 4 | Gene expression | Phosphoproteins | Clusters | Saliva
Journal Article
Bioinformatics, ISSN 1367-4803, 09/2016, Volume 32, Issue 18, pp. 2847 - 2849
Parallel heatmaps with carefully designed annotation graphics are powerful for efficient visualization of patterns and relationships among high dimensional... 
BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | Computer Graphics | Gene Expression | Software | Metabolic Networks and Pathways | Genomics | Humans
Journal Article
Journal of Biomechanics, ISSN 0021-9290, 2014, Volume 47, Issue 11, pp. 2598 - 2605
Abstract Mechanical cell properties play an important role in many basic biological functions, including motility, adhesion, proliferation and differentiation.... 
Physical Medicine and Rehabilitation | Parameter estimation | Epithelial–mesenchymal transition (EMT) | Actin filaments (AF) | Cytoskeletal drugs | Microfluidic optical stretcher (MOS) | High-throughput measurements | Mechanical cell properties | Vimentin intermediate filaments (VIF) | Cytochalasin-D | Finite Element Method (FEM) | Withaferin-A | Cancer | Epithelial-mesenchymal transition (EMT) | VISCOELASTIC PROPERTIES | CYTOSKELETON | ENGINEERING, BIOMEDICAL | CYTOCHALASIN | NETWORKS | DEFORMATION | FIBROBLASTS | EPITHELIAL-MESENCHYMAL TRANSITION | BIOPHYSICS | ACRYLAMIDE | Cell Line | Cytochalasin D - chemistry | Cell Proliferation | Rheology | Withanolides - chemistry | Humans | Stress, Mechanical | Intermediate Filaments - chemistry | Microtubules - metabolism | Phenotype | Cell Nucleus - metabolism | Cell Shape | Computer Simulation | Actins - chemistry | Cytoskeleton - metabolism | Finite Element Analysis | Vimentin - chemistry | Microscopy, Fluorescence | Usage | Computer-generated environments | Computer simulation | Actin | Analysis | Genetic aspects | Models | Muscle proteins | Intermediate filament proteins | Genotype & phenotype | Deformation | Simulation | Mechanics | Mechanical properties | Cytoskeleton | Population | Kinases | Drugs | Networks | Filaments | Mathematical analysis | Mathematical models | Formability
Journal Article
by Northcott, Paul A and Lee, Catherine and Zichner, Thomas and Stütz, Adrian M and Erkek, Serap and Kawauchi, Daisuke and Shih, David J. H and Hovestadt, Volker and Zapatka, Marc and Sturm, Dominik and Jones, David T. W and Kool, Marcel and Remke, Marc and Cavalli, Florence M. G and Zuyderduyn, Scott and Bader, Gary D and VandenBerg, Scott and Esparza, Lourdes Adriana and Ryzhova, Marina and Wang, Wei and Wittmann, Andrea and Stark, Sebastian and Sieber, Laura and Seker-Cin, Huriye and Linke, Linda and Kratochwil, Fabian and Jäger, Natalie and Buchhalter, Ivo and Imbusch, Charles D and Zipprich, Gideon and Raeder, Benjamin and Schmidt, Sabine and Diessl, Nicolle and Wolf, Stephan and Wiemann, Stefan and Brors, Benedikt and Lawerenz, Chris and Eils, Jürgen and Warnatz, Hans-Jörg and Risch, Thomas and Yaspo, Marie-Laure and Weber, Ursula D and Bartholomae, Cynthia C and von Kalle, Christof and Turányi, Eszter and Hauser, Peter and Sanden, Emma and Darabi, Anna and Siesjö, Peter and Sterba, Jaroslav and Zitterbart, Karel and Sumerauer, David and van Sluis, Peter and Versteeg, Rogier and Volckmann, Richard and Koster, Jan and Schuhmann, Martin U and Ebinger, Martin and Grimes, H. Leighton and Robinson, Giles W and Gajjar, Amar and Mynarek, Martin and von Hoff, Katja and Rutkowski, Stefan and Pietsch, Torsten and Scheurlen, Wolfram and Felsberg, Jörg and Reifenberger, Guido and Kulozik, Andreas E and von Deimling, Andreas and Witt, Olaf and Eils, Roland and Gilbertson, Richard J and Korshunov, Andrey and Taylor, Michael D and Lichter, Peter and Korbel, Jan O and Wechsler-Reya, Robert J and Pfister, Stefan M
Nature (London), ISSN 1476-4687, 2014, Volume 511, Issue 7510, pp. 428 - 434
Journal Article
eLife, ISSN 2050-084X, 2017, Volume 6
The recent advent of methods for high-throughput single-cell molecular profiling has catalyzed a growing sense in the scientific community that the time is... 
ANALYSIS REVEALS | CHROMATIN ACCESSIBILITY | MESSENGER-RNA | RNA-SEQ | BIOLOGY | GENE-EXPRESSION | LINEAGE ANALYSIS | DIFFUSION MAPS | TRANSCRIPTIONAL HETEROGENEITY | HEMATOPOIETIC STEM | FATE DECISIONS | Gene expression | Cells | Bioengineering | Disease | Laboratories | Computer engineering | Genomes | Biology | Biologists | Computer science | Medicine | Immunology | Microscopy | Cell cycle | Physiology | Cancer
Journal Article
Journal Article
by Jones, David T W and Hutter, Barbara and Jäger, Natalie and Korshunov, Andrey and Kool, Marcel and Warnatz, Hans-Jörg and Zichner, Thomas and Lambert, Sally R and Ryzhova, Marina and Quang, Dong Anh Khuong and Fontebasso, Adam M and Stütz, Adrian M and Hutter, Sonja and Zuckermann, Marc and Sturm, Dominik and Gronych, Jan and Lasitschka, Bärbel and Schmidt, Sabine and Şeker-Cin, Huriye and Witt, Hendrik and Sultan, Marc and Ralser, Meryem and Northcott, Paul A and Hovestadt, Volker and Bender, Sebastian and Pfaff, Elke and Stark, Sebastian and Faury, Damien and Schwartzentruber, Jeremy and Majewski, Jacek and Weber, Ursula D and Zapatka, Marc and Raeder, Benjamin and Schlesner, Matthias and Worth, Catherine L and Bartholomae, Cynthia C and von Kalle, Christof and Imbusch, Charles D and Radomski, Sylwester and Lawerenz, Chris and van Sluis, Peter and Koster, Jan and Volckmann, Richard and Versteeg, Rogier and Lehrach, Hans and Monoranu, Camelia and Winkler, Beate and Unterberg, Andreas and Herold-Mende, Christel and Milde, Till and Kulozik, Andreas E and Ebinger, Martin and Schuhmann, Martin U and Cho, Yoon-Jae and Pomeroy, Scott L and von Deimling, Andreas and Witt, Olaf and Taylor, Michael D and Wolf, Stephan and Karajannis, Matthias A and Eberhart, Charles G and Scheurlen, Wolfram and Hasselblatt, Martin and Ligon, Keith L and Kieran, Mark W and Korbel, Jan O and Yaspo, Marie-Laure and Brors, Benedikt and Felsberg, Jörg and Reifenberger, Guido and Collins, V Peter and Jabado, Nada and Eils, Roland and Lichter, Peter and the International Cancer Genome Consortium PedBrain Tumor Project and Int Canc Genome Consortium and International Cancer Genome Consortium PedBrain Tumor Project
Nature genetics, ISSN 1546-1718, 2013, Volume 45, Issue 8, pp. 927 - 932
Journal Article