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1. Full Text In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs
by Tefferi, Ayalew, MD and Kantarjian, Hagop, MD and Rajkumar, S. Vincent, MD and Baker, Lawrence H., DO and Abkowitz, Jan L., MD and Adamson, John W., MD and Advani, Ranjana Hira, MD and Allison, James, MD and Antman, Karen H., MD and Bast, Robert C., MD and Bennett, John M., MD and Benz, Edward J., MD and Berliner, Nancy, MD and Bertino, Joseph, MD and Bhatia, Ravi, MD and Bhatia, Smita, MD and Bhojwani, Deepa, MD and Blanke, Charles D., MD and Bloomfield, Clara D., MD and Bosserman, Linda, MD and Broxmeyer, Hal E., PhD and Byrd, John C., MD and Cabanillas, Fernando, MD and Canellos, George Peter, MD and Chabner, Bruce A., MD and Chanan-Khan, Asher, MD and Cheson, Bruce, MD and Clarkson, Bayard, MD and Cohn, Susan L., MD and Colon-Otero, Gerardo, MD and Cortes, Jorge, MD and Coutre, Steven, MD and Cristofanilli, Massimo, MD and Curran, Walter J., MD and Daley, George Q., MD, PhD and DeAngelo, Daniel J., MD, PhD and Deeg, H. Joachim, MD and Einhorn, Lawrence H., MD and Erba, Harry P., MD, PhD and Esteva, Francisco J., MD, PhD and Estey, Elihu, MD and Fidler, Isaiah J., DVM, PhD and Foran, James, MD and Forman, Stephen, MD and Freireich, Emil, MD and Fuchs, Charles, MD, MPH and George, James N., MD and Gertz, Morie A., MD and Giralt, Sergio, MD and Golomb, Harvey, MD and Greenberg, Peter, MD and Gutterman, Jordan, MD and Handin, Robert I., MD and Hellman, Samuel, MD and Hoff, Paulo Marcelo, MD and Hoffman, Ronald, MD and Hong, Waun Ki, MD and Horowitz, Mary, MD, MS and Hortobagyi, Gabriel N., MD and Hudis, Clifford, MD and Issa, Jean Pierre, MD and Johnson, Bruce Evan, MD and Kantoff, Philip W., MD and Kaushansky, Kenneth, MD and Khayat, David, MD, PhD and Khuri, Fadlo R., MD and Kipps, Thomas J., MD, PhD and Kripke, Margaret, PhD and Kyle, Robert A., MD and Larson, Richard A., MD and Lawrence, Theodore S., MD, PhD and Levine, Ross, MD and Link, Michael P., MD and Lippman, Scott M., MD and Lonial, Sagar, MD and Lyman, Gary H., MD, MPH and Markman, Maurie, MD and Mendelsohn, John, MD and Meropol, Neal J., MD and Messinger, Yoav, MD and Mulvey, Therese M., MD and O’Brien, Susan, MD and Perez-Soler, Roman, MD and Pollock, Raphael, MD, PhD and Prchal, Josef, MD and Press, Oliver, MD, PhD and Radich, Jerald, MD and Rai, Kanti, MD and Rosenberg, Saul A., MD and Rowe, Jacob M., MD and Rugo, Hope, MD and Runowicz, Carolyn D., MD and Sandmaier, Brenda M., MD and Saven, Alan, MD and Schafer, Andrew I., MD and Schiffer, Charles, MD and Sekeres, Mikkael A., MD, MS and Silver, Richard T., MD and Siu, Lillian L., MD and Steensma, David P., MD and ...
Mayo Clinic Proceedings, ISSN 0025-6196, 2015, Volume 90, Issue 8, pp. 996 - 1000
Internal Medicine | MEDICINE, GENERAL & INTERNAL | Drug Costs | United States - epidemiology | Neoplasms - economics | Humans | Patient Participation | Patient Advocacy | Antineoplastic Agents - economics | Neoplasms - epidemiology | Prescription Fees | Neoplasms - drug therapy | Antimitotic agents | Cancer patients | Patient outcomes | Economic aspects | Dosage and administration | Drug therapy | Antineoplastic agents
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2. Full Text Randomized Pilot Trial of a Telephone Symptom Management Intervention for Symptomatic Lung Cancer Patients and Their Family Caregivers
by Mosher, Catherine E., PhD and Winger, Joseph G., MS and Hanna, Nasser, MD and Jalal, Shadia I., MD and Einhorn, Lawrence H., MD and Birdas, Thomas J., MD and Ceppa, DuyKhanh P., MD and Kesler, Kenneth A., MD and Schmitt, Jordan, MD and Kashy, Deborah A., PhD and Champion, Victoria L., PhD, RN, FAAN
Journal of Pain and Symptom Management, ISSN 0885-3924, 2016, Volume 52, Issue 4, pp. 469 - 482
Abstract Context Lung cancer is one of the most common cancers affecting both men and women and is associated with high symptom burden and psychological... 
Anesthesia & Perioperative Care | Pain Medicine | distress | symptom management | family caregivers | psychosocial interventions | Lung cancer | cognitive-behavioral | PALLIATIVE CARE | SELF-EFFICACY | SIGNIFICANT OTHERS | MENTAL-HEALTH | CLINICAL NEUROLOGY | MEDICINE, GENERAL & INTERNAL | SOCIAL CONSTRAINTS | COGNITIVE-BEHAVIORAL THERAPY | DEPRESSIVE SYMPTOMATOLOGY | HEALTH CARE SCIENCES & SERVICES | PSYCHOLOGICAL DISTRESS | QUALITY-OF-LIFE | INFORMAL CAREGIVERS | Self Efficacy | Caregivers - psychology | Humans | Middle Aged | Self Report | Male | Lung Neoplasms - therapy | Pilot Projects | Telemedicine | Treatment Failure | Aged, 80 and over | Adult | Cognitive Therapy | Female | Aged | Disease Management | Lung Neoplasms - psychology | Patient Education as Topic | Caregivers | Medical colleges | Care and treatment | Cancer patients | Stress (Psychology) | lung cancer
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3. Full Text A 25-Year Single Institution Experience With Surgery for Primary Mediastinal Nonseminomatous Germ Cell Tumors
by Kesler, Kenneth A., MD and Rieger, Karen M., MD and Hammoud, Zane T., MD and Kruter, Laura E., MS and Perkins, Susan M., PhD and Turrentine, Mark W., MD and Schneider, Bryan P., MD and Einhorn, Lawrence H., MD and Brown, John W., MD
Annals of Thoracic Surgery, ISSN 0003-4975, 2008, Volume 85, Issue 2, pp. 371 - 378
Background The treatment of primary mediastinal nonseminomatous germ cell tumors (PMNSGCT) with cisplatin-based chemotherapy, followed by surgical resection of... 
Surgery | Cardiothoracic Surgery | TRIAL | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | THERAPY | CISPLATIN | RESPIRATORY SYSTEM | VINBLASTINE | TERM | IFOSFAMIDE | BLEOMYCIN-COMBINATION CHEMOTHERAPY | Multivariate Analysis | Predictive Value of Tests | Follow-Up Studies | Indiana | Humans | Male | Mediastinal Neoplasms - mortality | Cisplatin - administration & dosage | Mediastinal Neoplasms - drug therapy | Adult | Female | Neoplasms, Germ Cell and Embryonal - drug therapy | Registries | Retrospective Studies | Chemotherapy, Adjuvant | Child | Mediastinal Neoplasms - surgery | Neoplasms, Germ Cell and Embryonal - mortality | Risk Assessment | Proportional Hazards Models | Probability | Treatment Outcome | Academic Medical Centers | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mediastinal Neoplasms - pathology | Thoracotomy - methods | Adolescent | Survival Analysis | Neoplasms, Germ Cell and Embryonal - surgery | Neoplasm Staging | Neoplasms, Germ Cell and Embryonal - pathology | Chemotherapy | Germ cell tumors | Cancer | Index Medicus | Abridged Index Medicus
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4. Full Text Survival After Resection for Metastatic Testicular Nonseminomatous Germ Cell Cancer to the Lung or Mediastinum
by Kesler, Kenneth A., MD and Kruter, Laura E., MD and Perkins, Susan M., PhD and Rieger, Karen M., MD and Sullivan, Katherine J., MD and Runyan, Matthew L., MD and Brown, John W., MD and Einhorn, Lawrence H., MD
Annals of Thoracic Surgery, ISSN 0003-4975, 2011, Volume 91, Issue 4, pp. 1085 - 1093
Background Since the advent of cisplatin-based chemotherapy, nonseminomatous germ cell tumors (NSGCT) have been considered one of the most curable solid... 
Surgery | Cardiothoracic Surgery | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | PULMONARY METASTASECTOMY | RESPIRATORY SYSTEM | LONG-TERM SURVIVAL | TUMORS | RETROPERITONEAL | CHEMOTHERAPY | Neoplasms, Germ Cell and Embryonal - mortality | Testicular Neoplasms - therapy | Mediastinal Neoplasms - secondary | Testicular Neoplasms - mortality | Lung Neoplasms - mortality | Humans | Middle Aged | Male | Mediastinal Neoplasms - mortality | Survival Rate | Lung Neoplasms - therapy | Testicular Neoplasms - pathology | Young Adult | Lung Neoplasms - secondary | Mediastinal Neoplasms - therapy | Adolescent | Adult | Aged | Retrospective Studies | Child | Neoplasms, Germ Cell and Embryonal - therapy | Neoplasms, Germ Cell and Embryonal - secondary | Index Medicus | Abridged Index Medicus
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5. Full Text The “growing teratoma syndrome” in primary mediastinal nonseminomatous germ cell tumors: Criteria based on current practice
by Kesler, Kenneth A., MD and Patel, Jay B., MD and Kruter, Laura E., MD and Birdas, Thomas J., MD and Rieger, Karen M., MD and Okereke, Ikenna C., MD and Einhorn, Lawrence H., MD
Journal of Thoracic and Cardiovascular Surgery, The, ISSN 0022-5223, 2012, Volume 144, Issue 2, pp. 438 - 443
Objective Criteria for the growing teratoma syndrome in patients with primary mediastinal nonseminomatous germ cell tumors have not been well established... 
Cardiothoracic Surgery
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6. Full Text Mediastinal Germ Cell Tumors
by Kesler, Kenneth A., MD and Einhorn, Lawrence H., MD
Annals of Thoracic Surgery, ISSN 0003-4975, 2007, Volume 83, Issue 5, pp. 1915 - 1915
Surgery | Cardiothoracic Surgery | SURGERY | RESPIRATORY SYSTEM | CARDIAC & CARDIOVASCULAR SYSTEMS | Neoplasms, Germ Cell and Embryonal | Humans | Mediastinal Neoplasms
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7. Post Chemotherapy RPLND in Patients with Elevated Markers: Current Concepts and Clinical Outcome
by Beck, Stephen D.W and Foster, Richard S and Bihrle, Richard and Einhorn, Lawrence H and Donohue, John P
Urologic Clinics of North America, ISSN 0094-0143, 05/2007, Volume 34, Issue 2, pp. 219 - 225
Elevated serum tumor markers after cisplatin-based chemotherapy usually contraindicate surgery because of the presence of active germ-cell elements; however,... 
LYMPH-NODE DISSECTION | SURGERY | SALVAGE | MANAGEMENT | THERAPY | GERM-CELL TUMORS | UROLOGY & NEPHROLOGY | SURGICAL RESECTION | Testicular Neoplasms - therapy | Humans | Retroperitoneal Space - surgery | Male | Treatment Outcome | Antineoplastic Agents - therapeutic use | Clinical Trials as Topic | Neoplasms, Germ Cell and Embryonal - blood | Biomarkers, Tumor - blood | Chemotherapy, Adjuvant | Lymph Node Excision - methods | Testicular Neoplasms - blood | Neoplasms, Germ Cell and Embryonal - therapy
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8. Multimodality treatment of germ cell tumors of the mediastinum
by Kesler, Kenneth A and Einhorn, Lawrence H
Thoracic surgery clinics, ISSN 1547-4127, 02/2009, Volume 19, Issue 1, pp. 63 - 69
Germ cell tumors originating in the anterior mediastinal compartment represent a rare but biologically interesting group of neoplasms. Knowledge of the... 
Diagnostic Imaging | Neoplasms, Germ Cell and Embryonal - mortality | Mediastinal Neoplasms - therapy | Humans | Mediastinal Neoplasms - mortality | Antineoplastic Agents - therapeutic use | Thoracic Surgical Procedures | Mediastinal Neoplasms - diagnosis | Biomarkers, Tumor | Neoplasms, Germ Cell and Embryonal - therapy | Neoplasms, Germ Cell and Embryonal - diagnosis | Index Medicus
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9. Full Text THE DEVELOPMENT OF NON-GERM CELL MALIGNANCIES WITHIN GERM-CELL TUMORS - A CLINICOPATHOLOGIC STUDY OF 11 CASES
by ULBRIGHT, TM and LOEHRER, PJ and ROTH, LM and EINHORN, LH and WILLIAMS, SD and CLARK, SA
CANCER, ISSN 0008-543X, 1984, Volume 54, Issue 9, pp. 1824 - 1833
Eleven male patients had germ cell tumors of the testis (7), mediastinum (3), or retroperitoneum (1) in which non-germ cell malignancies developed. Such... 
ONCOLOGY | Teratoma - pathology | Mediastinal Neoplasms - pathology | Humans | Adolescent | Adult | Male | Retroperitoneal Neoplasms - pathology | Sarcoma - pathology | Child | Testicular Neoplasms - pathology | Wilms Tumor - pathology
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10. Full Text Chemotherapy of disseminated germ cell tumors
by Einhorn, L H
Cancer, ISSN 0008-543X, 08/1987, Volume 60, Issue 3 Suppl, p. 570
The treatment of patients with germ cell neoplasms has improved dramatically during the last 10 years. Combination chemotherapy with cisplatin + vinblastine +... 
Prospective Studies | Drug Administration Schedule | Humans | Male | Clinical Trials as Topic | Combined Modality Therapy | Bleomycin - administration & dosage | Random Allocation | Vinblastine - administration & dosage | Cisplatin - administration & dosage | Testicular Neoplasms - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | Adult | Neoplasms, Germ Cell and Embryonal - drug therapy | Neoplasm Staging | Doxorubicin - administration & dosage | Neoplasms, Germ Cell and Embryonal - secondary
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11. Full Text Toxicity comparisons between two chemotherapy regimens as adjuvant or salvage treatment in nonseminomatous testicular cancer
by Weiss, R B and Stablein, D M and Muggia, F M and Einhorn, L H and Golbey, R B and DeWys, W D
Cancer, ISSN 0008-543X, 07/1988, Volume 62, Issue 1, p. 18
The Testicular Cancer Intergroup Study was initiated to evaluate the efficacy of adjuvant chemotherapy in Stage II and salvage therapy in Stage I... 
Skin Diseases - chemically induced | Testicular Neoplasms - drug therapy | Vinblastine - adverse effects | Dactinomycin - adverse effects | Humans | Leukopenia - chemically induced | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Cisplatin - adverse effects | Male | Bleomycin - adverse effects | Mucous Membrane - drug effects | Hearing Disorders - chemically induced
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12. Full Text BACON (bleomycin, adriamycin, CCNU, oncovin and nitrogen mustard) in squamous lung cancer. Experience in fifty patients
by Livingston, R B and Fee, W H and Einhorn, L H and Burgess, M A and Freireich, E J and Gottlieb, J A and Farber, M O
Cancer, ISSN 0008-543X, 03/1976, Volume 37, Issue 3, p. 1237
Fifty patients with inoperable squamous carcinoma of the lung. 38 with extensive, and 12 with limited disease, were treated with BACON. Tumor regression... 
Doxorubicin - therapeutic use | Lung Neoplasms - drug therapy | Lung Neoplasms - mortality | Humans | Lomustine - adverse effects | Mechlorethamine - adverse effects | Male | Clinical Trials as Topic | Bleomycin - adverse effects | Mechlorethamine - therapeutic use | Carcinoma, Squamous Cell - drug therapy | Carcinoma, Squamous Cell - mortality | Bleomycin - therapeutic use | Vincristine - therapeutic use | Vincristine - adverse effects | Lomustine - therapeutic use | Drug Therapy, Combination | Doxorubicin - adverse effects
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13. Full Text Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial
by Bohula, Erin A and Scirica, Benjamin M and Inzucchi, Silvio E and Inzucchi, Silvio and McGuire, Darren K and Keech, Anthony C and Keech, Anthony and Smith, Steven R and Smith, S and Kanevsky, Estella and Murphy, Sabina A and Leiter, Lawrence A and Dwyer, Jamie P and Dwyer, Jamie and Corbalan, Ramon and Hamm, Christian and Kaplan, Lee and Nicolau, Jose Carlos and Ophuis, Ton Oude and Ray, Kauski and Ray, Kausik K and Ruda, Mikhail and Spinar, Jindrich and Patel, S and Patel, R and Patel, Tushar and Miao, Wenfeng and Perdomo, Carlos and Francis, Bruce and Dhadda, Shobha and Bonaca, Marc P and Ruff, Christian T and Sabatine, Marc S and Wiviott, Stephen D and Satlin, Andrew and Brown, Conville and Brown, J and Budaj, Andrzej and Garcia-Castillo, Armando and Gupta, N and Gupta, Milan and Oude Ophuis, Ton and Weissman, Neil and White, Harvey D and White, A and White, J and Amerena, J and Arstall, M and Colquhoun, D and Jayasinghe, R and Lee, A and Lee, J and Lehman, R and Moses, R and Proietto, J and Purnell, P and Waites, J and Blombery, P and Cross, D and Worthley, M and d'Emden, M and Selvanayagam, J and Oqueli, RE and Whelan, A and Garrahy, P and de Looze, F and Ninio, D and Horowitz, J and William, M and Suranyi, M and Wittert, G and Le May, M and Pandey, AS and Vizel, S and Labonte, R and Beaudry, Y and Fortin, C and Bell, A and Kouz, S and St-Amour, É and Bata, I and St Maurice, F and Chehayeb, R and Constance, C and Wong, G and Hess, A and Liutkus, J and Poirier, P and Teitelbaum, I and Berlingieri, J and Cha, J and Hartleib, M and Heffernan, M and Twum-Barima, D and Pandith, V and Aronson, R and Goldenberg, R and Ajala, B and Jain, A and Ross, S and ... and CAMELLIA-TIMI61 Steering Comm and CAMELLIA-TIMI 61 Steering Committee Investigators
The Lancet, ISSN 0140-6736, 11/2018, Volume 392, Issue 10161, pp. 2269 - 2279
There is a direct relationship between bodyweight and risk of diabetes. Lorcaserin, a selective serotonin 2C receptor agonist that suppresses appetite, has... 
LIFE-STYLE INTERVENTION | MEDICINE, GENERAL & INTERNAL | THERAPY | LIRAGLUTIDE | REDUCTION | CARDIOVASCULAR OUTCOMES | WEIGHT-LOSS | BARIATRIC SURGERY | FOLLOW-UP | ASSOCIATION | Glycated Hemoglobin A - analysis | Hypoglycemic Agents - therapeutic use | Overweight - complications | Atherosclerosis - drug therapy | Double-Blind Method | Obesity - complications | Humans | Middle Aged | Diabetes Mellitus, Type 2 - prevention & control | Prediabetic State - prevention & control | Body Weight - drug effects | Atherosclerosis - complications | Male | Prediabetic State - complications | Weight Loss - drug effects | Appetite Depressants - therapeutic use | Prediabetic State - drug therapy | Remission Induction | Diabetes Mellitus, Type 2 - blood | Benzazepines - therapeutic use | Female | Aged | Diabetes Mellitus, Type 2 - drug therapy | Diabetes Mellitus, Type 2 - complications | Type 2 diabetes | Prevention | Clinical trials | Obesity | Analysis | Diabetic retinopathy | Heart attacks | Body weight | Cardiovascular disease | Diabetic neuropathy | Body weight loss | Risk factors | Body mass index | Randomization | Hyperglycemia | Vascular diseases | Motivation | Atherosclerosis | Hemoglobin | Remission | Diabetes mellitus (non-insulin dependent) | Appetite | Hypertension | Serotonin | Complications | Diabetes mellitus | Weight loss | Health risks | FDA approval | Hypoglycemia | Metabolism | Risk analysis | Patients | Disease control | Disease prevention | Weight control | Statistical models | Arteriosclerosis | Coronary vessels | Microvasculature | Lifestyles | Gastrointestinal surgery | Diabetes | Health risk assessment | Long-term effects
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14. AACE/ACE comprehensive diabetes management algorithm 2015
by Garber, Alan J and Abrahamson, Martin J and Barzilay, Joshua I and Blonde, Lawrence and Bloomgarden, Zachary T and Bush, Michael A and Dagogo-Jack, Samuel and Davidson, Michael B and Einhorn, Daniel and Garber, Jeffrey R and Garvey, W Timothy and Grunberger, George and Handelsman, Yehuda and Hirsch, Irl B and Jellinger, Paul S and McGill, Janet B and Mechanick, Jeffrey I and Rosenblit, Paul D and Umpierrez, Guillermo and Davidson, Michael H
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, ISSN 1530-891X, 04/2015, Volume 21, Issue 4, pp. 438 - 447
ENDOCRINOLOGY & METABOLISM | Diabetes Mellitus - blood | Comprehensive Health Care | Algorithms | Blood Glucose - analysis | Cardiovascular Diseases - prevention & control | Diabetes Mellitus - therapy | Humans | Insulin - therapeutic use
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15. Full Text (Sample) size matters! An examination of sample size from the SPRINT trial study to prospectively evaluate reamed intramedullary nails in patients with tibial fractures
by Bhandari, Mohit and Tornetta, Paul and Rampersad, Shelly-Ann and Sprague, Sheila and Heels-Ansdell, Diane and Sanders, David W and Schemitsch, Emil H and Swiontkowski, Marc and Walter, Stephen and Guyatt, Gordon and Buckingham, Lisa and Leece, Pamela and Viveiros, Helena and Mignott, Tashay and Ansell, Natalie and Sidorkewicz, Natalie and Agel, Julie and Bombardier, Claire and Berlin, Jesse A and Bosse, Michael and Browner, Bruce and Gillespie, Brenda and O'Brien, Peter and Poolman, Rudolf and Macleod, Mark D and Carey, Timothy and Leitch, Kellie and Bailey, Stuart and Gurr, Kevin and Konito, Ken and Bartha, Charlene and Low, Isolina and MacBean, Leila V and Ramu, Mala and Reiber, Susan and Strapp, Ruth and Tieszer, Christina and Kreder, Hans and Stephen, David J. G and Axelrod, Terry S and Yee, Albert J. M and Richards, Robin R and Finkelstein, Joel and Holtby, Richard M and Cameron, Hugh and Cameron, John and Gofton, Wade and Murnaghan, John and Schatztker, Joseph and Bulmer, Beverly and Conlan, Lisa and Laflamme, Yves and Berry, Gregory and Beaumont, Pierre and Ranger, Pierre and Laflamme, Georges-Henri and Jodoin, Alain and Renaud, Eric and Gagnon, Sylvain and Maurais, Gilles and Malo, Michel and Fernandes, Julio and Latenesse, Kim and Poirier, Marie-France and Daigneault, Gina and McKee, Michael M and Waddell, James P and Bogoch, Earl R and Daniels, Timothy R and McBroom, Robert R and Vicente, Milena R and Storey, Wendy and Wild, Lisa M and McCormack, Robert and Perey, Bertrand and Goetz, Thomas J and Pate, Graham and Penner, Murray J and Panagiotopoulos, Kostas and Pirani, Shafique and Dommisse, Ian G and Loomer, Richard L and Stone, Trevor and Moon, Karyn and Zomar, Mauri and Webb, Lawrence X and Teasdall, Robert D and Birkedal, John Peter and Martin, David Franklin and Ruch, David S and Kilgus, Douglas J and Pollock, David C and Harris, Mitchel Brion and Wiesler, Ethan Ron and Ward, William G and Shilt, Jeffrey Scott and Koman, Anew L and Poehling, Gary G and Kulp, Brenda and Creevy, William R and ... and SPRINT Investigators
Journal of orthopaedic trauma, ISSN 0890-5339, 2013, Volume 27, Issue 4, pp. 183 - 188
Inadequate sample size and power in randomized trials can result in misleading findings. This study demonstrates the effect of sample size in a large clinical... 
intramedullary nailing | sample size | tibia fracture | SPORT SCIENCES | RANDOMIZED-TRIALS | POWER | ORTHOPEDICS | Young Adult | Tibial Fractures - surgery | Fracture Fixation, Intramedullary - methods | Sample Size | Bone Nails | Fractures, Closed - surgery | Humans | Middle Aged | Adult | Female | Male | Fractures, Open - surgery
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16. Full Text Prognostic factors for predicting outcomes after intramedullary nailing of the tibia
by Schemitsch, Emil H and Bhandari, Mohit and Guyatt, Gordon and Sanders, David W and Swiontkowski, Marc and Tornetta, Paul and Walter, Stephen D and Zdero, Rad and Goslings, J. C and Teague, David and Jeray, Kyle and McKee, Michael D and Sprague, Sheila and Heels-Ansdell, Diane and Buckingham, Lisa and Leece, Pamela and Viveiros, Helena and Mignott, Tashay and Ansell, Natalie and Sidorkewicz, Natalie and Agel, Julie and Bombardier, Claire and Berlin, Jesse A and Bosse, Michael and Browner, Bruce and Gillespie, Brenda and Jones, Alan and O'Brien, Peter and Poolman, Rudolf and Kreder, Hans J and Stephen, David J. G and Axelrod, Terry S and Yee, Albert J. M and Richards, Robin R and Finkelstein, Joel and Gofton, Wade and Murnaghan, John and Schatztker, Joseph and Ford, Michael and Bulmer, Beverly and Conlan, Lisa and Laflamme, G. Yves and Berry, Gregory and Beaumont, Pierre and Ranger, Pierre and Laflamme, Georges-Henri and Gagnon, Sylvain and Malo, Michel and Fernandes, Julio and Poirier, Marie-France and Waddell, James P and Bogoch, Earl R and Daniels, Timothy R and McBroom, Robert R and Vicente, Milena R and Storey, Wendy and Wild, Lisa M and McCormack, Robert and Perey, Bertrand and Goetz, Thomas J and Pate, Graham and Penner, Murray J and Panagiotopoulos, Kostas and Pirani, Shafique and Dommisse, Ian G and Loomer, Richard L and Stone, Trevor and Moon, Karyn and Zomar, Mauri and Webb, Lawrence X and Teasdall, Robert D and Birkedal, John Peter and Martin, David Franklin and Ruch, David S and Kilgus, Douglas J and Pollock, David C and Harris, Mitchel Brion and Wiesler, Ethan Ron and Ward, William G and Shilt, Jeffrey Scott and Koman, Anew L and Poehling, Gary G and Kulp, Brenda and Creevy, William R and Stein, Anew B and Bono, Christopher T and Einhorn, Thomas A and Brown, Desmond and Pacicca, Donna and Sledge, John B and Foster, Timothy E and Voloshin, Ilva and Bolton, Jill and Carlisle, Hope and Shaughnessy, Lisa and Obremskey, William T and LeCroy, C. Michael and Meinberg, Eric G and Messer, Terry M and Craig, William L and ... and Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients with Tibial Fractures (SPRINT) Investigators
Journal of bone and joint surgery. American volume, ISSN 0021-9355, 2012, Volume 94A, Issue 19, pp. 1786 - 1793
Prediction of negative postoperative outcomes after long-bone fracture treatment may help to optimize patient care. We recently completed the Study to... 
SURGERY | OPEN FRACTURES | EXTERNAL FIXATION | MANAGEMENT | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | SHAFT FRACTURES | RATS | INDOMETHACIN | CLOSED FRACTURES | RANDOMIZED-TRIAL | BLOOD-FLOW | ORTHOPEDICS | Multivariate Analysis | Predictive Value of Tests | Confidence Intervals | Prognosis | Prospective Studies | Bone Nails | Humans | Middle Aged | Tibial Fractures - diagnostic imaging | Male | Injury Severity Score | Patient Selection | Young Adult | Tibial Fractures - surgery | Fracture Healing - physiology | Adult | Female | Odds Ratio | Postoperative Complications - physiopathology | Risk Assessment | Logistic Models | Treatment Outcome | Postoperative Care - methods | Radiography | Fracture Fixation, Intramedullary - methods | Weight-Bearing | Pain Measurement | Ontario | Fracture Fixation, Intramedullary - adverse effects | Postoperative Complications - diagnostic imaging | Scientific
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