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European Journal of Cell Biology, ISSN 0171-9335, 2012, Volume 91, Issue 1, pp. 36 - 47
The current view of cytoplasmic RNA-mediated innate immune signaling involves the differential activation of the RNA helicases retinoic acid-inducible gene 1... 
Ubiquitin | RNA helicases | PRRs | Innate immunity | IPS-1 | Regulation | Proinflammatory cytokines | ISG | Type I IFN | DOUBLE-STRANDED-RNA | RIG-I | TUMOR-SUPPRESSOR CYLD | CELL BIOLOGY | ANTIVIRAL RESPONSES | ISG15 CONJUGATION | INDUCIBLE GENE-I | NEGATIVE REGULATION | IFN-BETA PROMOTER | NF-KAPPA-B | E3 UBIQUITIN LIGASE | RNA Helicases - metabolism | Humans | Virus Diseases - virology | Mitochondria - immunology | Interferon Type I - immunology | Interferon-Induced Helicase, IFIH1 | Interferon Type I - biosynthesis | Signal Transduction - immunology | Mitochondria - genetics | Gene Expression - immunology | Adaptor Proteins, Signal Transducing - immunology | RNA Helicases - genetics | Membrane Proteins - metabolism | DEAD-box RNA Helicases - metabolism | Cell Line | Virus Diseases - immunology | Nerve Tissue Proteins - immunology | Membrane Proteins - genetics | Viruses - metabolism | Cell Communication | Membrane Proteins - immunology | Virus Diseases - metabolism | Viruses - immunology | Mitochondria - metabolism | Signal Transduction - genetics | Ubiquitination - immunology | Immunity, Innate | Nerve Tissue Proteins - genetics | Host-Pathogen Interactions | Nerve Tissue Proteins - metabolism | DEAD-box RNA Helicases - genetics | Animals | Adaptor Proteins, Signal Transducing - genetics | DEAD-box RNA Helicases - immunology | Mice | RNA Helicases - immunology | Adaptor Proteins, Signal Transducing - metabolism | Virus Replication - physiology | Virus diseases | Antiviral agents | RNA | Genes | Melanoma | Physiological aspects | Biological response modifiers | Health aspects
Journal Article
Molecular Cell, ISSN 1097-2765, 2008, Volume 29, Issue 2, pp. 169 - 179
The ATPase RIG-I senses viral RNAs that contain 5′-triphosphates in the cytoplasm. It initiates a signaling cascade that activates innate immune response by... 
RNA | MOLIMMUNO | RESPONSES | HELICASE LGP2 | VIRUS | ACID | REPLICATION | RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTIVIRAL INNATE IMMUNITY | HOST | IDENTIFICATION | ADAPTER PROTEIN | CELL BIOLOGY | RNA Caps - immunology | RNA Helicases - metabolism | Zinc - metabolism | Humans | rab GTP-Binding Proteins - genetics | Structure-Activity Relationship | RNA Helicases - chemistry | Interferons - immunology | RNA Caps - metabolism | Zinc - chemistry | Adenosine Triphosphatases - immunology | Interferon-Induced Helicase, IFIH1 | RNA, Viral - genetics | Immunity, Innate - physiology | RNA Caps - chemistry | Zinc - immunology | RNA Helicases - genetics | RNA, Viral - metabolism | Interferons - genetics | DEAD-box RNA Helicases - metabolism | DEAD-box RNA Helicases - chemistry | Dimerization | RNA Caps - genetics | rab GTP-Binding Proteins - metabolism | Cell Line | DEAD Box Protein 58 | Adenosine Triphosphatases - metabolism | Protein Structure, Tertiary - genetics | Binding Sites - genetics | Substrate Specificity - genetics | Polyphosphates - metabolism | DEAD-box RNA Helicases - genetics | Animals | RNA, Viral - chemistry | Polyphosphates - immunology | rab GTP-Binding Proteins - immunology | DEAD-box RNA Helicases - immunology | Interferons - metabolism | Adenosine Triphosphatases - chemistry | RNA, Viral - immunology | rab GTP-Binding Proteins - chemistry | Adenosine Triphosphatases - genetics | Structural Homology, Protein | RNA Helicases - immunology | Polyphosphates - chemistry | Sensors | G proteins | Biological response modifiers | Adenosine triphosphatase | Index Medicus
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2014, Volume 1169, pp. 55 - 65
Journal Article
Gastroenterology, ISSN 0016-5085, 2009, Volume 136, Issue 7, pp. 2247 - 2257
Journal Article
Blood, ISSN 0006-4971, 10/2013, Volume 122, Issue 15, pp. 2591 - 2599
Key Points Systemic virus infection leads to rapid disruption of the Peyer’s patches but not of peripheral lymph nodes. Virus-associated innate immune... 
Journal Article