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Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 225 - 225
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14_Supplement, pp. 225 - 225
MnSOD detoxifies superoxide and impacts tumor biology by generating H2O2 which can diffuse through the mitochondrial membrane and affect metabolism and... 
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 10/2015, Volume 87, p. S63
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 10/2015, Volume 87, pp. S63 - S63
Journal Article
Nature Communications, ISSN 2041-1723, 2015, Volume 6, Issue 1, pp. 6053 - 6053
Manganese superoxide dismutase (MnSOD/SOD2) is a mitochondria-resident enzyme that governs the types of reactive oxygen species egressing from the organelle to... 
HYPOXIA-INDUCIBLE FACTOR | LIFE-SPAN | OXIDATIVE STRESS | ACTIVATED PROTEIN-KINASE | EPITHELIAL-CELLS | MANGANESE SUPEROXIDE-DISMUTASE | MULTIDISCIPLINARY SCIENCES | INHIBIT APOPTOSIS | C-MYC | CELL-CYCLE PROGRESSION | BREAST | Mitochondria - enzymology | RNA, Small Interfering - genetics | AMP-Activated Protein Kinases - metabolism | Colonic Neoplasms - genetics | Superoxide Dismutase - genetics | Reactive Oxygen Species - metabolism | Humans | Transcriptional Activation | Gene Expression Regulation, Neoplastic | Phosphofructokinase-1 - genetics | Superoxide Dismutase - antagonists & inhibitors | Male | Glycolysis - genetics | Breast Neoplasms - enzymology | Prostatic Neoplasms - genetics | Mitochondria - genetics | Female | Hexokinase - genetics | Superoxide Dismutase - metabolism | Prostatic Neoplasms - pathology | Oxidation-Reduction | Pyruvate Kinase - metabolism | Signal Transduction | AMP-Activated Protein Kinases - antagonists & inhibitors | Hydrogen Peroxide - metabolism | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Colonic Neoplasms - pathology | Cell Line, Tumor | Prostatic Neoplasms - enzymology | Colonic Neoplasms - enzymology | Hexokinase - metabolism | Neoplasm Staging | Phosphofructokinase-1 - metabolism | Pyruvate Kinase - genetics | AMP-Activated Protein Kinases - genetics | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Turkish Journal of Biology, ISSN 1300-0152, 2014, Volume 38, Issue 6, pp. 748 - 753
Reactive oxygen species (ROS) are generated during mitochondrial oxidative metabolism. Accumulation of ROS without an effective antioxidant response can lead... 
Glutathione peroxidase | Oxidative stress | Selenium | Cancer | Manganese superoxide dismutase | RAT HEPATOCYTES | MNSOD | PROSTATE-CANCER RISK | CELL-GROWTH | POLYMORPHISM | BREAST-CANCER | SIGNAL-TRANSDUCTION | selenium | GLUTATHIONE-PEROXIDASE-1 | BIOLOGY | manganese superoxide dismutase | cancer | HYDROGEN-PEROXIDE | CORONARY-ARTERY-DISEASE | glutathione peroxidase
Journal Article
The Prostate, ISSN 0270-4137, 04/2019, Volume 79, Issue 5, pp. 462 - 467
Background:NKX3.1 is a tumor suppressor frequently lost in prostate cancer. Previous studies by others indicated that the risks associated with reduced NKX3.1... 
selenium | selenoproteins | prostatectomy | MORTALITY | VITAMIN-E | GENETIC POLYMORPHISMS | PREVENTION | RISK | SUPPLEMENTATION | ENDOCRINOLOGY & METABOLISM | UROLOGY & NEPHROLOGY | FUNCTIONAL VARIANT | EXPRESSION | ASSOCIATION | Genotype & phenotype | Vitamin E | Tumor suppressor genes | Selenium | Supplementation | Nkx3.1 protein | Gene polymorphism | Prostate | Prostate cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, pp. e93472 - e93472
Glutathione peroxidase activity was previously determined to be elevated in lymphocytes obtained from patients treated with the Bcr-Abl kinase inhibitor... 
CHRONIC MYELOGENOUS LEUKEMIA | MEDIATED DECAY | RAT-TISSUES | PROTEIN | MESSENGER-RNA | MULTIDISCIPLINARY SCIENCES | SELENOPROTEIN SYNTHESIS | GENE-EXPRESSION | HYDROPEROXIDE GLUTATHIONE-PEROXIDASE | SELENOCYSTEINE INCORPORATION | CELL-LINE | Glutathione Peroxidase - metabolism | Protein Biosynthesis | Selenoproteins - genetics | TOR Serine-Threonine Kinases - metabolism | Imatinib Mesylate - pharmacology | Antioxidants - metabolism | Humans | Phosphatidylinositol 3-Kinases - metabolism | Enzyme Activation - drug effects | Sirolimus - pharmacology | Glutathione Peroxidase - genetics | Selenoproteins - metabolism | Gene Expression Regulation - drug effects | Fusion Proteins, bcr-abl - genetics | Signal Transduction - drug effects | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Protein Kinase Inhibitors - pharmacology | Fusion Proteins, bcr-abl - metabolism | RNA | Analysis | Selenoproteins | TOR protein | BCR protein | Phosphorylation | Peptides | Leukemia | Oxidizing agents | mRNA | Infections | Kinases | Proteins | Antioxidants | Oxidants | Lymphocytes | Coding | Rodents | Penicillin | Peroxidase | Selenium | Fusion protein | Public health | Glutathione | Glutathione peroxidase | Enzymes | Imatinib | Myeloid leukemia | Selenocysteine | Abl protein | Rapamycin | Chronic myeloid leukemia | Tumor cell lines | Gene expression | Pathology | Signaling | Inhibitors | Cell lines | Stem cells | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, pp. e0127295 - e0127295
Journal Article
The Prostate, ISSN 0270-4137, 03/2018, Volume 78, Issue 4, pp. 279 - 288
Journal Article
Journal Article
01/2016, ISBN 1369432186
Selenium exerts its functions mainly through its incorporation into selenoproteins, which contain the amino acid selenocysteine. Animal and epidemiological,... 
Pathology | Oncology
Dissertation
Journal Article