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Chemico-Biological Interactions, ISSN 0009-2797, 01/2018, Volume 279, pp. 84 - 94
Impaired apoptosis and systemic toxicity of chemotherapeutic drugs make cancer treatment suboptimal. Thus, there is urgency for drug repurposing which... 
BCL-2 | Hepatocellular carcinoma | TRAILR2 | TRAIL | Doxorubicin | Chloroquine | APOPTOSIS | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | CARDIOMYOPATHY | DEATH | MECHANISMS | DRUG-RESISTANCE | AUTOPHAGY | GROWTH-FACTOR-BETA | THERAPEUTIC TARGET | PHARMACOLOGY & PHARMACY | TOXICOLOGY | Index Medicus
Journal Article
Chemico-biological interactions, 11/2017, Volume 279, p. 84
Impaired apoptosis and systemic toxicity of chemotherapeutic drugs make cancer treatment suboptimal. Thus, there is urgency for drug repurposing which... 
Journal Article
Journal Article
Scientia Pharmaceutica, ISSN 0036-8709, 12/2018, Volume 86, Issue 4, p. 44
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related mortality worldwide. In an attempt to understand some potential mechanisms of... 
Mfap4 | Hcc | Oxidized coenzyme q10 | Fibrotic indices | Oxidative status | Oxidative stress | Liver diseases | Cytokines | Mortality | Oncology | Infections | Outpatient care facilities | Antioxidants | Proteins | Liver cancer | Hepatitis | Blood platelets | Biomarkers | Interferon | MFAP4 | HCC | oxidized Coenzyme Q10 | oxidative status | fibrotic indices
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 04/2014, Volume 728, Issue 1, pp. 151 - 160
Hepatocellular carcinoma (HCC) is resistant to conventional chemotherapy, and is rarely amenable to radiotherapy. Heparanase, enzyme attacks heparan sulfate... 
Fibroblast Growth Factor (FGF)-2 | Intrinsic cell death | Heparan sulfate proteoglycans (HSPGs) | Glucosamine | Glucuronic acid | Extrinsic cell death | ANGIOGENESIS | MAMMALIAN HEPARANASE | FIBROBLAST-GROWTH-FACTOR | SULFATE PROTEOGLYCANS | IN-VITRO | LIVER-INJURY | INTRINSIC APOPTOSIS | CANCER METASTASIS | INFLAMMATION | TUMOR-METASTASIS | PHARMACOLOGY & PHARMACY | Humans | Middle Aged | Liver Neoplasms, Experimental - chemically induced | Male | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Suramin - administration & dosage | Carcinoma, Hepatocellular - drug therapy | Heparan Sulfate Proteoglycans - genetics | Suramin - therapeutic use | Adult | Female | Glucuronidase - antagonists & inhibitors | Liver Neoplasms - pathology | Antineoplastic Agents - pharmacology | Liver Neoplasms - enzymology | Liver Neoplasms, Experimental - pathology | Suramin - pharmacology | Liver Neoplasms - drug therapy | Rats | Carcinoma, Hepatocellular - enzymology | Rats, Sprague-Dawley | Animals | Glucuronidase - genetics | Liver Neoplasms, Experimental - drug therapy | Heparan Sulfate Proteoglycans - metabolism | Carcinoma, Hepatocellular - pathology | Survival Analysis | Liver Neoplasms, Experimental - enzymology | Oxidative Stress - drug effects | Antioxidants | Enzymes | Chemotherapy | Glycosaminoglycans | Analysis | Drugstores | Fibroblast growth factors | Glycoproteins | Hepatoma | Sulfates | Gene expression | Cancer
Journal Article
Journal Article
European Cytokine Network, ISSN 1148-5493, 2013, Volume 24, Issue 4, pp. 139 - 147
Purpose: The use of cisplatin, the first of the platinum-containing anti-cancer drugs, is limited by the development of a myriad of adverse reactions,... 
TGF-βR1 | SB-431542 | SOD | TGF-β1 | sCD93 | MDA | Caspase-3 | Cisplatin | OXIDATIVE STRESS | PROTEIN | TGF-beta 1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | GREEN-TEA EGCG | KINASE | INJURY | ALPHA | TGF-beta R1 | DIABETIC-NEPHROPATHY | IMMUNOLOGY | CELL BIOLOGY | SQUAMOUS-CELL CARCINOMA | cisplatin | HUMAN OVARIAN-CANCER | caspase-3 | Index Medicus
Journal Article
Scientia Pharmaceutica, ISSN 0036-8709, 03/2017, Volume 85, Issue 1, p. 9
Elevated serum levels of cystatin C are found to be related to poor outcome and metastatic potential of some malignant disorders. To evaluate the clinical... 
Extra-nodal involvement | Survival | Cystatin C | Diffuse large B-cell lymphoma | cystatin C | extra-nodal involvement | diffuse large B-cell lymphoma | survival
Journal Article
Scientia Pharmaceutica, ISSN 0036-8709, 2014, Volume 82, Issue 1, pp. 129 - 145
Breast cancer is by far the most common cancer in women worldwide and the main cause of cancer-related mortality. Breast cancer accounts for 38% of all... 
Total antioxidant capacity (TAC) | Breast cancer | Carcinoma antigen 15-3 (CA15-3) | Matrix metalloproteinase-9 (MMP-9) | Human epidermal growth factor receptor-2 (HER2) | Nitric oxide (NO) | Carcinoma Antigen 15-3 (CA15-3)
Journal Article
Inflammation and Allergy - Drug Targets, ISSN 1871-5281, 02/2014, Volume 13, Issue 1, pp. 74 - 79
Simvastatin has important immune-modulatory and anti-inflammatory effects independent of lipid lowering effects. Therefore, our study was conducted to... 
Journal Article
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