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Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 01/2012, Volume 22, Issue 1, pp. 327 - 333
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 11/2019, Volume 181, pp. 111573 - 111573
The carbonic anhydrase (CA) inhibitory activity of newly synthesized compounds – against the human CA (hCA) isoforms I, II, IX, and XII was measured and... 
Synthesis | Phthalimide | Sulfonamide | Carbonic anhydrase | Acetazolamide | Anthranilic acid | Molecular docking | Index Medicus
Journal Article
Journal Article
Journal Article
Bioorganic Chemistry, ISSN 0045-2068, 03/2019, Volume 83, pp. 198 - 204
The synthesis, characterization and biological evaluation of series of cyclic imides incorporating the 4-sulfamoylbenzamide scaffold ( – is disclosed. The... 
Imide | Sulfonamide | Anti-tumor | Carbonic anhydrase | Anti-glaucoma | Inhibition | Heterocycle | DESIGN | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | SULFONAMIDES | DISCOVERY | VII | BIOLOGICAL EVALUATION | XII | EXPRESSION | Glaucoma | Exhibitions | Chemical properties | Sulfonamides | Analysis
Journal Article
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2016, Volume 121, pp. 410 - 421
A new series of 2-substituted mercapto-4(3 )-quinazolinone were synthesized and assessed for anti-inflammatory and analgesic activities and inhibition of... 
Docking study | Synthesis | 2-Mercapto-4(3H)-quinazolinone | Cyclooxygenase-1/cyclooxygenase-2 inhibition assay | Anti-inflammatory activities | inhibition assay | Cyclooxygenase-1/cyclooxygenase-2 | SELECTIVE-INHIBITION | DESIGN | CHEMISTRY, MEDICINAL | CYCLOOXYGENASE-2 | ANALOGS | ANTITUMOR-ACTIVITY | DRUGS | BIOLOGICAL EVALUATION | DERIVATIVES | PROSTAGLANDIN SYNTHESIS | QUINAZOLINES | Analgesics - pharmacology | Analgesics - metabolism | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Cyclooxygenase 2 Inhibitors - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Analgesics - chemical synthesis | Cyclooxygenase 1 - chemistry | Cyclooxygenase 2 Inhibitors - metabolism | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Quinazolinones - pharmacology | Cyclooxygenase 2 Inhibitors - chemical synthesis | Chemistry Techniques, Synthetic | Cyclooxygenase 2 Inhibitors - pharmacology | Cyclooxygenase 2 - chemistry | Quinazolinones - chemical synthesis | Animals | Analgesics - chemistry | Cyclooxygenase 2 - metabolism | Protein Conformation | Mice | Molecular Docking Simulation | Quinazolinones - chemistry | Cyclooxygenase 1 - metabolism | Quinazolinones - metabolism | Drugstores | COX-2 inhibitors | Pharmacy | Diclofenac | Index Medicus
Journal Article
Journal Article
Journal of Molecular Structure, ISSN 0022-2860, 06/2016, Volume 1113, pp. 133 - 145
A comprehensive structural and vibrational study of 2-(4-oxo-3-phenethyl-3,4-dihydroquinazolin-2-ylthio)-N-(3,4,5-trimethoxyphenyl) acetamide is reported.... 
FT-IR | DFT | Quinazoline | FT-Raman | Molecular docking | NBO ANALYSIS | SERS | AB-INITIO | HOMO-LUMO | CHEMISTRY, PHYSICAL | AGENTS | DERIVATIVES | Orbitals | Phenyls | Mathematical analysis | Optical properties | Nonlinearity | Docking | Charge transfer | Electrostatics
Journal Article
Journal Article