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by Voight, Benjamin F, PhD and Peloso, Gina M, PhD and Orho-Melander, Marju, PhD and Frikke-Schmidt, Ruth, DMSc and Barbalic, Maja, PhD and Jensen, Majken K, PhD and Hindy, George, MD and Hólm, Hilma, MD and Ding, Eric L, ScD and Johnson, Toby, PhD and Schunkert, Heribert, Prof and Samani, Nilesh J, Prof and Clarke, Robert, MD and Hopewell, Jemma C, PhD and Thompson, John F, Prof and Li, Mingyao, PhD and Thorleifsson, Gudmar, PhD and Newton-Cheh, Christopher, MD and Musunuru, Kiran, MD and Pirruccello, James P, BS and Saleheen, Danish, MBBS and Chen, Li, MSc and Stewart, Alexandre FR, PhD and Schillert, Arne, PhD and Thorsteinsdottir, Unnur, PhD and Thorgeirsson, Gudmundur, MD and Anand, Sonia, Prof and Engert, James C, PhD and Morgan, Thomas, MD and Spertus, John, Prof and Stoll, Monika, Prof and Berger, Klaus, Prof and Martinelli, Nicola, MD and Girelli, Domenico, Prof and McKeown, Pascal P, Prof and Patterson, Christopher C, PhD and Epstein, Stephen E, MD and Devaney, Joseph, PhD and Burnett, Mary-Susan, PhD and Mooser, Vincent, MD and Ripatti, Samuli, PhD and Surakka, Ida, BSci and Nieminen, Markku S, Prof and Sinisalo, Juha, MD and Lokki, Marja-Liisa, PhD and Perola, Markus, Prof and Havulinna, Aki, PhD and de Faire, Ulf, Prof and Gigante, Bruna, MD and Ingelsson, Erik, PhD and Zeller, Tanja, PhD and Wild, Philipp, MD and de Bakker, Paul I W, Prof and Klungel, Olaf H, PhD and Maitland-van der Zee, Anke-Hilse, PhD and Peters, Bas J M, PhD and de Boer, Anthonius, Prof and Grobbee, Diederick E, Prof and Kamphuisen, Pieter W, PhD and Deneer, Vera H M, PhD and Elbers, Clara C, PhD and Onland-Moret, N Charlotte, PhD and Hofker, Marten H, Prof and Wijmenga, Cisca, Prof and Verschuren, WM Monique, PhD and Boer, Jolanda MA, PhD and van der Schouw, Yvonne T, Prof and Rasheed, Asif and Frossard, Philippe and Demissie, Serkalem, PhD and Willer, Cristen, PhD and Do, Ron, PhD and Ordovas, Jose M, Prof and Abecasis, Gonçalo R, Prof and Boehnke, Michael, Prof and Mohlke, Karen L, PhD and Daly, Mark J, PhD and Guiducci, Candace, BS and Burtt, Noël P, BS and Surti, Aarti, BS and Gonzalez, Elena, BS and Purcell, Shaun, PhD and Gabriel, Stacey, PhD and Marrugat, Jaume, PhD and Peden, John, PhD and Erdmann, Jeanette, PhD and Diemert, Patrick, MD and Willenborg, Christina, MSc and König, Inke R, PhD and Fischer, Marcus, MD and Hengstenberg, Christian, MD and Ziegler, Andreas, PhD and Buysschaert, Ian, MD and Lambrechts, Diether, PhD and Van de Werf, Frans, Prof and Fox, Keith A, Prof and El Mokhtari, Nour Eddine, MD and Rubin, Diana, MD and Schrezenmeir, Jürgen, PhD and Schreiber, Stefan, Prof and ...
Lancet, The, ISSN 0140-6736, 08/2012, Volume 380, Issue 9841, pp. 572 - 580
Journal Article
by Webb, Thomas R., PhD and Erdmann, Jeanette, PhD and Stirrups, Kathleen E., PhD and Stitziel, Nathan O., MD, PhD and Masca, Nicholas G.D., PhD and Jansen, Henning, MD and Kanoni, Stavroula, PhD and Nelson, Christopher P., PhD and Ferrario, Paola G., PhD and König, Inke R., PhD and Eicher, John D., PhD and Johnson, Andrew D., PhD and Hamby, Stephen E., PhD and Betsholtz, Christer, PhD and Ruusalepp, Arno, MD, PhD and Franzén, Oscar, PhD and Schadt, Eric E., MD, PhD and Björkegren, Johan L.M., MD, PhD and Weeke, Peter E., MD, PhD and Auer, Paul L., PhD and Schick, Ursula M., PhD and Lu, Yingchang, MD, PhD and Zhang, He, PhD and Dube, Marie-Pierre, PhD and Goel, Anuj, MSc and Farrall, Martin, MD and Peloso, Gina M., PhD and Won, Hong-Hee, PhD and Do, Ron, PhD and van Iperen, Erik, MSc and Kruppa, Jochen, PhD and Mahajan, Anubha, PhD and Scott, Robert A., PhD and Willenborg, Christina, PhD and Braund, Peter S., PhD and van Capelleveen, Julian C., MD and Doney, Alex S.F., MD, PhD and Donnelly, Louise A., PhD and Asselta, Rosanna, PhD and Merlini, Pier A., MD and Duga, Stefano, PhD and Marziliano, Nicola, PhD and Denny, Josh C., MD, MS and Shaffer, Christian, BS and El-Mokhtari, Nour Eddine, MD and Franke, Andre, PhD and Heilmann, Stefanie, PhD and Hengstenberg, Christian, MD and Hoffmann, Per, PhD and Holmen, Oddgeir L., MD and Hveem, Kristian, MD, PhD and Jansson, Jan-Håkan, MD, PhD and Jöckel, Karl-Heinz, PhD and Kessler, Thorsten, MD and Kriebel, Jennifer, PhD and Laugwitz, Karl L., MD and Marouli, Eirini, MSc and Martinelli, Nicola, MD, PhD and McCarthy, Mark I., MD and Van Zuydam, Natalie R., PhD and Meisinger, Christa, MD, MPH and Esko, Tõnu, PhD and Mihailov, Evelin, MSc and Escher, Stefan A., PhD and Alver, Maris, MSc and Moebus, Susanne, PhD and Morris, Andrew D., MD and Virtamo, Jarma, MD, PhD and Nikpay, Majid, PhD and Olivieri, Oliviero, MD and Provost, Sylvie, MSc and AlQarawi, Alaa, BSc and Robertson, Neil R., MSc and Akinsansya, Karen O., PhD and Reilly, Dermot F., PhD and Vogt, Thomas F., PhD and Yin, Wu, PhD and Asselbergs, Folkert W., MD, PhD and Kooperberg, Charles, PhD and Jackson, Rebecca D., MD and Stahl, Eli, PhD and Müller-Nurasyid, Martina, PhD and Strauch, Konstantin, PhD and Varga, Tibor V., PhD and Waldenberger, Melanie, PhD and Zeng, Lingyao, MSc and Chowdhury, Rajiv, MD, PhD and Salomaa, Veikko, MD, PhD and Ford, Ian, PhD and Jukema, J. Wouter, MD, PhD and Amouyel, Philippe, MD, PhD and Kontto, Jukka, MSSc and Nordestgaard, Børge G., MD, DMSc and Ferrières, Jean, MD and Saleheen, Danish, MBBS, PhD and Sattar, Naveed, PhD and Surendran, Praveen, PhD and Wagner, Aline, MD, PhD and Young, Robin, PhD and Howson, Joanna M.M., PhD and ... and Wellcome Trust Case Control and MORGAM Investigators and Myocardial Infarction Genetics and Wellcome Trust Case Control Consortium and Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Medicin
Journal of the American College of Cardiology, ISSN 0735-1097, 2017, Volume 69, Issue 7, pp. 823 - 836
Abstract Background Genome-wide association studies have so far identified 56 loci associated with risk of coronary artery disease (CAD). Many CAD loci show... 
Cardiovascular | Internal Medicine | expression quantitative trait loci | genetics | genome-wide association | single nucleotide polymorphism | cholesteryl ester transfer protein | SR-BI | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | CETP MASS | SUSCEPTIBILITY | RISK | PHOSPHOLIPASE A | VARIANT | SCAVENGER RECEPTOR | ABDOMINAL AORTIC-ANEURYSM | Genome-Wide Association Study | Gene Frequency | Humans | Coronary Artery Disease - genetics | Female | Male | Coronary Artery Disease - epidemiology | Genetic Pleiotropy | Polymorphism, Single Nucleotide | Genetic Loci | Odds Ratio | Case-Control Studies | Coronary heart disease | Analysis | Genealogy | Cardiovascular disease | Genomes | Metabolism | Gene expression | Blood | Risk factors | Studies | Celiac disease | Lipoproteins | Coronary vessels | Rheumatoid arthritis | Quality control | Calcification | Diabetes | Bioinformatics | LD, linkage disequilibrium | CETP, cholesteryl ester transfer protein | eQTL, expression quantitative trait locus | CAD, coronary artery disease | GWAS, genome-wide association study | BMI, body mass index | SNP, single nucleotide polymorphism | HDL, high-density lipoprotein | LDL, low-density lipoprotein | Original Investigation | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Kardiologi | Medical Genetics | Medicinsk genetik | Clinical Medicine | Cardiac and Cardiovascular Systems | Medicinska och farmaceutiska grundvetenskaper
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2013, Volume 61, Issue 9, pp. 957 - 970
Journal Article
by Butterworth, Adam S and Braund, Peter S and Farrall, Martin and Hardwick, Robert J and Saleheen, Danish and Peden, John F and Soranzo, Nicole and Chambers, John C and Sivapalaratnam, Suthesh and Kleber, Marcus E and Keating, Brendan and Qasim, Atif and Klopp, Norman and Erdmann, Jeanette and Assimes, Themistocles L and Ball, Stephen G and Balmforth, Anthony J and Barnes, Timothy A and Basart, Hanneke and Baumert, Jens and Bezzina, Connie R and Boerwinkle, Eric and Boehm, Bernhard O and Brocheton, Jessy and Bugert, Peter and Cambien, Francois and Clarke, Robert and Codd, Veryan and Collins, Rory and Couper, David and Cupples, L. Aienne and de Jong, Jonas S and Diemert, Patrick and Ejebe, Kenechi and Elbers, Clara C and Elliott, Paul and Fornage, Myriam and Franzosi, Maria-Grazia and Frossard, Philippe and Garner, Stephen and Goel, Anuj and Goodall, Alison H and Hengstenberg, Christian and Hunt, Sarah E and Kastelein, John J. P and Klungel, Olaf H and Klüter, Harald and Koch, Kerstin and König, Inke R and Kooner, Angad S and Laaksonen, Reijo and Lathrop, Mark and Li, Mingyao and Liu, Kiang and McPherson, Ruth and Musameh, Muntaser D and Musani, Solomon and Nelson, Christopher P and O'Donnell, Christopher J and Ongen, Halit and Papanicolaou, George and Peters, Annette and Peters, Bas J. M and Potter, Simon and Psaty, Bruce M and Qu, Liming and Rader, Daniel J and Rasheed, Asif and Rice, Catherine and Scott, James and Seedorf, Udo and Sehmi, Joban S and Sotoodehnia, Nona and Stark, Klaus and Stephens, Jonathan and van der Schoot, C. Ellen and van der Schouw, Yvonne T and Thorsteinsdottir, Unnur and Tomaszewski, Maciej and van der Harst, Pim and Vasan, Ramachanan S and Wilde, Arthur A. M and Willenborg, Christina and Winkelmann, Bernhard R and Zaidi, Moazzam and Zhang, Weihua and Ziegler, Aneas and de Bakker, Paul I. W and Koenig, Wolfgang and Mätz, Winfried and Trip, Mieke D and Reilly, Muredach P and Kathiresan, Sekar and Schunkert, Heribert and Hamsten, Anders and Hall, Alistair S and Kooner, Jaspal S and Thompson, Simon G and Thompson, John R and Deloukas, Panos and ... and IBC 50K CAD Consortium and The IBC 50K CAD Consortium
PLoS genetics, ISSN 1553-7390, 2011, Volume 7, Issue 9, p. e1002260
Journal Article
European Heart Journal, ISSN 0195-668X, 4/2014, Volume 35, Issue 16, pp. 1069 - 1077
Journal Article
PLOS ONE, ISSN 1932-6203, 08/2008, Volume 3, Issue 8, p. e2986
Background: Rare mutations of the low-density lipoprotein receptor gene (LDLR) cause familial hypercholesterolemia, which increases the risk for coronary... 
POPULATION | HEART-DISEASE | METAANALYSIS | MYOCARDIAL-INFARCTION | CARDIOVASCULAR EVENTS | BIOLOGY | POLYMORPHISM | HYPERCHOLESTEROLEMIA | PREVALENCE | EPIDEMIOLOGY | GENOME-WIDE ASSOCIATION | Receptors, LDL - genetics | Oligonucleotide Array Sequence Analysis | Risk Assessment | Humans | Risk Factors | Cholesterol, LDL - drug effects | Chromosome Mapping | Random Allocation | Case-Control Studies | Genetic Variation | Cholesterol, LDL - genetics | Coronary Disease - prevention & control | Anticholesteremic Agents - therapeutic use | Coronary Disease - genetics | Cholesterol, LDL - blood | Polymorphism, Single Nucleotide | Chromosomes, Human, Pair 10 | Medical research | Hypercholesterolemia | Blood cholesterol | Low density lipoproteins | Genes | Medicine, Experimental | Genetic research | Genetics | Genetic aspects | Single nucleotide polymorphisms | Coronary heart disease | Risk factors | Lipoproteins (low density) | Risk | Lipids | Cardiovascular disease | Genomes | Single-nucleotide polymorphism | Gene polymorphism | Epidemiology | Consortia | Confidence intervals | Randomization | Population | Lipoprotein (low density) receptors | Children | Heart diseases | Statistical analysis | Mortality | Coronary artery | Health risks | Environmental health | Genetic diversity | Regression analysis | Metabolism | LDLR gene | Apolipoproteins | Coronary artery disease | Low density lipoprotein | Cholesterol | Studies | Genetic variance | Hospitals | Coronary vessels | Alleles | Biomarkers | Receptor density | Adults | Mutation | Polymorphism
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2017, Volume 12, Issue 8, p. e0182999
textabstractGlatiramer acetate is used therapeutically in multiple sclerosis but also known for adverse effects including elevated coronary artery disease... 
CELLS | GROWTH-FACTOR-BETA | ACTIVATION | TGF-BETA | MULTIPLE-SCLEROSIS | MECHANISM | MULTIDISCIPLINARY SCIENCES | ATHEROSCLEROSIS | RECEPTORS | EXPRESSION | ASSOCIATION | Genetic Predisposition to Disease | Glatiramer Acetate - adverse effects | Humans | Cardiovascular Diseases - chemically induced | Polymorphism, Single Nucleotide | Cardiovascular Diseases - genetics | Case-Control Studies | Linkage Disequilibrium | Glatiramer acetate | Complications and side effects | Multiple sclerosis | Analysis | Genetic aspects | Dosage and administration | Research | Drug therapy | Health risk assessment | Coronary heart disease | Risk factors | Chromosome 19 | Drugs | Copolymer 1 | Heart attacks | Genes | Linkage disequilibrium | Risk | Cardiovascular disease | Genomes | Single-nucleotide polymorphism | Epidemiology | Consortia | Blood platelets | Atherosclerosis | Genetics | Cardiology | Heart diseases | Growth factors | Hypertension | Antigens | Transforming growth factor-b1 | Coronary artery | Health risks | Gene expression | Coronary artery disease | Studies | Side effects | Hospitals | Coronary vessels | In vivo methods and tests | Cardiovascular diseases | In vitro methods and tests | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article