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Lancet Neurology, The, ISSN 1474-4422, 2009, Volume 8, Issue 7, pp. 643 - 653
Summary Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is the most common heritable cause of stroke and... 
Neurology | SUBCORTICAL INFARCTS | POSITRON-EMISSION-TOMOGRAPHY | WHITE-MATTER | VASCULAR COGNITIVE IMPAIRMENT | HEREDITARY MULTIINFARCT DEMENTIA | AUTOSOMAL-DOMINANT ARTERIOPATHY | NOTCH3 MUTATIONS | TRANSGENIC MOUSE MODEL | LEUKOENCEPHALOPATHY CADASIL | CONDITION CAUSING STROKE | CLINICAL NEUROLOGY | CADASIL - pathology | Muscle, Smooth, Vascular - metabolism | Humans | Brain Infarction - pathology | Receptors, Notch - genetics | Muscle, Smooth, Vascular - physiopathology | Migraine with Aura - pathology | Brain - blood supply | CADASIL - therapy | Migraine with Aura - physiopathology | Genetic Predisposition to Disease - genetics | Cerebral Arteries - physiopathology | Brain Ischemia - physiopathology | Brain Infarction - physiopathology | Brain Ischemia - etiology | CADASIL - genetics | Disease Progression | Brain Infarction - etiology | Muscle, Smooth, Vascular - pathology | Cerebral Arteries - metabolism | Brain Ischemia - pathology | Cerebral Arteries - pathology | Migraine with Aura - etiology | Brain - pathology | Receptor, Notch3 | Brain damage | Cell research | Cysteine | Migraine | Genetically modified organisms | Dementia | Neuroimaging | Headache | Animal models | Stroke | vascular dementia | Cognitive ability | Clinical trials | Smooth muscle | Arteries | Reviews | Magnetic resonance imaging | Genetic engineering | Notch protein | Mutation | Age
Journal Article
2017, Current Topics in Environmental Health and Preventive Medicine, ISBN 9789811027109
This book presents the latest findings on biological, epidemiological, and clinical investigations of RNF213, which is thought to be involved in many... 
Medicine | Neurology | Neurosurgery | Public health
Web Resource
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 07/2015, Volume 112, Issue 27, pp. 8421 - 8426
Cerebral cavernous malformation (CCM) is a disease of the central nervous system causing hemorrhage-prone multiple lumen vascular malformations and very severe... 
Cerebral cavernous malformation | Sulindac metabolites | catenin | Endothelial cells | Vascular pathology | cerebral cavernous malformation | beta-catenin | endothelial cells | SIGNALING CONTROLS | MULTIDISCIPLINARY SCIENCES | BLOOD-BRAIN-BARRIER | EFFECTOR | CEREBRAL CAVERNOUS MALFORMATIONS | vascular pathology | PATHWAY | RAP1 | DISEASE | JUNCTIONS | GROWTH | sulindac metabolites | Immunohistochemistry | Central Nervous System Neoplasms - metabolism | Endothelial Cells - metabolism | Central Nervous System Neoplasms - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Hemangioma, Cavernous, Central Nervous System - drug therapy | beta Catenin - metabolism | Hemangioma, Cavernous, Central Nervous System - genetics | Hemangioma, Cavernous, Central Nervous System - metabolism | beta Catenin - genetics | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Mice, Knockout | Intracellular Signaling Peptides and Proteins - deficiency | Sulindac - analogs & derivatives | Animals | Signal Transduction - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Central Nervous System Neoplasms - drug therapy | Intracellular Signaling Peptides and Proteins - genetics | Sulindac - pharmacology | Transforming Growth Factor beta - metabolism | Disease Models, Animal | Usage | Sulindac | Genetic aspects | Research | Drug therapy | Health aspects | Cerebrovascular disease | Biological Sciences | β-catenin | Other Medical Sciences not elsewhere specified | Other Medical Sciences | Medical and Health Sciences | Medicin och hälsovetenskap | Annan medicin och hälsovetenskap | Övrig annan medicin och hälsovetenskap
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2015, Volume 112, Issue 27, p. 8421
  Cerebral cavernous malformation (CCM) is a disease of the central nervous system causing hemorrhage-prone multiple lumen vascular malformations and very... 
Rodents | Medical treatment | Nervous system | Pharmacology | Cells
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 07/2015, Volume 112, Issue 27, pp. 8421 - 8421
Cerebral cavernous malformation (CCM) is a disease of the central nervous system causing hemorrhage-prone multiple lumen vascular malformations and very severe... 
Journal Article
02/2017, 1st ed. 2017, Current Topics in Environmental Health and Preventive Medicine, ISBN 9789811027109, 183
This book presents the latest findings on biological, epidemiological, and clinical investigations of RNF213, which is thought to be involved in many... 
Neurology | Public Health | Neurosurgery | Medicine & Public Health
eBook
by Debette, Stéphanie and Goeggel Simonetti, Barbara and Schilling, Sabrina and Martin, Juan José and Kloss, Manja and Sarikaya, Hakan and Hausser, Ingrid and Engelter, Stefan and Metso, Tiina M and Pezzini, Alessandro and Thijs, Vincent and Touzé, Emmanuel and Paolucci, Stefano and Costa, Paolo and Sessa, Maria and Samson, Yves and Béjot, Yannick and Altintas, Ayse and Metso, Antti J and Hervé, Dominique and Lichy, Christoph and Jung, Simon and Fischer, Urs and Lamy, Chantal and Grau, Armin and Chabriat, Hugues and Caso, Valeria and Lyrer, Philippe A and Stapf, Christian and Tatlisumak, Turgut and Brandt, Tobias and Tournier-Lasserve, Elisabeth and Germain, Dominique P and Frank, Michael and Baumgartner, Ralf W and Grond-Ginsbach, Caspar and Bousser, Marie-Germaine and Leys, Didier and Dallongeville, Jean and Bersano, Anna and Arnold, Marcel and Abboud, Shérine and Pandolfo, Massimo and Bodenant, Marie and Louillet, Fabien and Mas, Jean-Louis and Leder, Sara and Léger, Anne and Deltour, Sandrine and Crozier, Sophie and Méresse, Isabelle and Canaple, Sandrine and Godefroy, Olivier and Giroud, Maurice and Decavel, Pierre and Medeiros, Elizabeth and Montiel, Paola and Moulin, Thierry and Vuillier, Fabrice and Amouyel, Philippe and Wiest, Tina and Werner, Inge and Arnold, Marie-Luise and Dos Santos, Michael and Dichgans, Martin and Thomas-Feles, Constanze and Weber, Ralf and Del Zotto, Elisabetta and Giossi, Alessia and Volonghi, Irene and Padovani, Alessandro and Poli, Loris and Morotti, Andrea and Lanfranconi, Silvia and Baron, Pierluigi and Beretta, Simone and Ferrarese, Carlo and Giacolone, Giacomo and Fluri, Felix and Hatz, Florian and Gisler, Dominique and Bonati, Leo and Gensicke, Henrik and Amort, Margareth and Markus, Hugh and Worrall, Bradford B and Southerland, Andrew M and Majersik, Jennifer J and Meschia, James F and Cole, John and Kittner, Steven and Buffon, Fréderique and Mawet, Jérôme and Heldner, Mirjam R and Mattle, Heinrich P and Gralla, Jan and CADISP Plus Consortium and CADISP-plus consortium and For the CADISP-plus consortium
Neurology, ISSN 0028-3878, 11/2014, Volume 83, Issue 22, pp. 2023 - 2031
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2015, Volume 112, Issue 27, pp. 8421 - 8426
Cerebral cavernous malformation (CCM) is a disease of the central nervous system causing hemorrhage-prone multiple lumen vascular malformations and very severe... 
Journal Article
Archives of Neurology, ISSN 0003-9942, 09/2011, Volume 68, Issue 9, p. 1110
  Stroke-related translational research is multifaceted. Herein, we highlight genome-wide association studies and genetic studies of cerebral autosomal... 
Stroke | Biomarkers | Genomes | Mutation | Molecular biology | Cells
Journal Article
Archives of Neurology, ISSN 0003-9942, 01/2011, Volume 68, Issue 9, pp. 1110 - 1123
Stroke-related translational research is multifaceted. Herein, we highlight genome-wide association studies and genetic studies of cerebral autosomal dominant... 
Journal Article
Sang Thrombose Vaisseaux, ISSN 0999-7385, 02/1996, Volume 8, Issue 2, pp. 106 - 111
Journal Article
Current Opinion in Cell Biology, ISSN 0955-0674, 2010, Volume 22, Issue 5, pp. 651 - 658
Endothelial cells form cell–cell adhesive structures, called adherens and tight junctions, which maintain tissue integrity, but must be dynamic for leukocyte... 
Internal Medicine | TIGHT JUNCTIONS | TYROSINE PHOSPHORYLATION | IN-VIVO | DEPENDENT ENDOCYTOSIS | VASCULAR-PERMEABILITY | ADHERENS JUNCTIONS | GROWTH-FACTOR | BETA-CATENIN | BLOOD-BRAIN-BARRIER | UP-REGULATION | CELL BIOLOGY | Animals | Endothelial Cells | Cadherins - metabolism | Humans | Cell-Matrix Junctions | Neovascularization, Physiologic | Antigens, CD - metabolism | Endothelium
Journal Article
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