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Nature Communications, ISSN 2041-1723, 04/2017, Volume 8, Issue 1, pp. 14816 - 14816
Human actin-related protein 2/3 complex (Arp2/3), required for actin filament branching, has two ARPC1 component isoforms, with ARPC1B prominently expressed in... 
F-ACTIN | CELL-MIGRATION | ACTIN POLYMERIZATION | LEADING-EDGE | MULTIDISCIPLINARY SCIENCES | WISKOTT-ALDRICH-SYNDROME | SYNDROME PROTEIN | MEGAKARYOCYTE | LAMELLIPODIA | PROPLATELET FORMATION | WASP | Index Medicus
Journal Article
Gut, ISSN 0017-5749, 06/2017, Volume 66, Issue 6, pp. 1060 - 1073
ObjectivePatients with Niemann–Pick disease type C1 (NPC1), a lysosomal lipid storage disorder that causes neurodegeneration and liver damage, can present with... 
IBD-GENETICS | IBD CLINICAL | IMMUNODEFICIENCY | IBD BASIC RESEARCH | Crohn'S DISEASE | MIGLUSTAT THERAPY | PATHOGENESIS | APOPTOSIS | DENDRITIC CELLS | MACROPHAGES | SUSCEPTIBILITY | ILEAL MUCOSA | PHAGOSOME PROTEOME | GASTROENTEROLOGY & HEPATOLOGY | BOWEL-DISEASE | INNATE IMMUNITY | Tumor Necrosis Factor-alpha - metabolism | Crohn Disease - genetics | X-Linked Inhibitor of Apoptosis Protein - deficiency | Humans | Child, Preschool | Lysosomes | Male | Nod2 Signaling Adaptor Protein - genetics | Leukocytes, Mononuclear | Pyridazines - pharmacology | Niemann-Pick Disease, Type C - physiopathology | Autophagy - drug effects | Crohn Disease - complications | Receptor-Interacting Protein Serine-Threonine Kinase 2 - metabolism | Young Adult | Gentamicins - pharmacology | Adult | Bacteria | Female | Genetic Diseases, X-Linked - genetics | Autophagy - genetics | Child | Receptor-Interacting Protein Serine-Threonine Kinase 2 - antagonists & inhibitors | Macrophages - physiology | Granuloma - genetics | Cells, Cultured | Chlorpromazine - pharmacology | Imidazoles - pharmacology | Acetylmuramyl-Alanyl-Isoglutamine - metabolism | X-Linked Inhibitor of Apoptosis Protein - genetics | Acetylmuramyl-Alanyl-Isoglutamine - pharmacology | Granuloma - pathology | Nod2 Signaling Adaptor Protein - metabolism | Crohn Disease - pathology | Dopamine Antagonists - pharmacology | Adolescent | X-Linked Inhibitor of Apoptosis Protein - metabolism | Macrophages - drug effects | Anti-Bacterial Agents - pharmacology | Protein Kinase Inhibitors - pharmacology | Mutation | Niemann-Pick Disease, Type C - complications | Niemann-Pick Disease, Type C - genetics | Autophagy (Cytology) | Inflammatory bowel diseases | Gastrointestinal diseases | Causes of | Colorectal diseases | Crohn's disease | Research | Niemann-Pick disease | Salmonella | Granuloma | Muramyl dipeptide | Liver | XIAP protein | Kinases | Macrophages | Autophagy | Defects | Genotype & phenotype | Cell activation | Intestine | Neurodegeneration | Npc1 protein | Age | NOD2 protein | Oligomerization | Dendritic cells | Cytokines | Blood & organ donations | Inflammation | Patients | Crohns disease | Studies | Inflammatory bowel disease | Monocytes | Proteomics | Colitis | Adapter proteins | Phagocytosis | Apoptosis | Index Medicus | Abridged Index Medicus | IBD - GENETICS | CROHN'S DISEASE | Inflammatory Bowel Disease | 1506
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2017, Volume 292, Issue 19, pp. 7904 - 7920
Journal Article
Gastroenterology, ISSN 0016-5085, 2014, Volume 147, Issue 3, pp. 680 - 689.e2
Journal Article
Gastroenterology, ISSN 0016-5085, 2014, Volume 146, Issue 4, pp. 1028 - 1039
Journal Article
Journal of Pediatric Surgery, ISSN 0022-3468, 2015, Volume 50, Issue 1, pp. 140 - 143
Abstract Purpose Children with perianal Crohn’s disease (PCD) are a unique and diverse patient population. The purpose of this study was to describe the... 
Pediatrics | Surgery | Perianal | Pediatric | Crohn’s disease
Journal Article
Inflammatory Bowel Diseases, ISSN 1078-0998, 02/2019, Volume 25, Issue 3, pp. 445 - 459
Abstract Background This systematic review critically analyzes the current research on micronutrient deficiency in children with inflammatory bowel disease... 
YOUNG-ADULTS | 25-HYDROXYVITAMIN D CONCENTRATIONS | BONE-MINERAL DENSITY | CROHNS-DISEASE | VITAMIN-D STATUS | ANTIOXIDANT CONCENTRATIONS | IRON-DEFICIENCY | micronutrient deficiency | vitamin D deficiency | CHILDREN | NUTRITIONAL-STATUS | ADOLESCENTS | nutritional assessment | iron deficiency | GASTROENTEROLOGY & HEPATOLOGY | pediatric nutrition
Journal Article
Gastroenterology, ISSN 0016-5085, 2016, Volume 150, Issue 5, pp. 1196 - 1207
Background & Aims Severe forms of inflammatory bowel disease (IBD) that develop in very young children can be caused by variants in a single gene. We performed... 
Gastroenterology and Hepatology | VEOIBD | Antiviral and Antibacterial Networks | NF-kB | DOMAIN | LIGASE ACTIVITY | PROTEIN | SUSCEPTIBILITY | XIAP | IDENTIFICATION | OXIDASE COMPLEX | MUTATIONS | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | REVEALS | Crohn Disease - genetics | Humans | Crohn Disease - metabolism | Databases, Genetic | England | Gene Regulatory Networks | Protein Interaction Maps | Exome | Genetic Variation | Transfection | Crohn Disease - diagnosis | Minor Histocompatibility Antigens - genetics | Female | Infant, Newborn | Repressor Proteins - metabolism | Severity of Illness Index | Genetic Predisposition to Disease | Genetic Association Studies | Signal Transduction | Cells, Cultured | Computational Biology | Repressor Proteins - genetics | Tripartite Motif Proteins - genetics | Gene Expression Profiling - methods | Crohn Disease - therapy | Homozygote | Minor Histocompatibility Antigens - metabolism | Phenotype | Nod2 Signaling Adaptor Protein - metabolism | Pedigree | Age of Onset | Consanguinity | Tripartite Motif Proteins - metabolism | Australia | Ontario | Germany | Virus diseases | Medical colleges | Molecular genetics | Analysis | Gastrointestinal diseases | Children's hospitals | Research institutes | Colitis | Cells | Index Medicus | Abridged Index Medicus | risk | genetics | susceptibility | CDAI
Journal Article
Journal of Pediatric Surgery, ISSN 0022-3468, 2016, Volume 51, Issue 12, pp. 1993 - 1997
Journal Article
Clinical and Translational Gastroenterology, ISSN 2155-384X, 01/2014, Volume 5, Issue 1, pp. e46 - e46
OBJECTIVES: The NOS2 gene encodes for the inducible nitric oxide synthase (iNOS), responsible for nitric oxide (NO) production, which contributes to... 
NUMBER | GENE | ULCERATIVE-COLITIS | LOCI | IBD | GASTROENTEROLOGY & HEPATOLOGY | ASSOCIATION | Inflammatory Bowel Disease
Journal Article