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1. Full Text Stone, Steven Michael
by Wohlgelernter, Elli
2007, Volume 19, 1
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2. Full Text The evolutionary history of lethal metastatic prostate cancer
by Gundem, Gunes and Van Loo, Peter and Kremeyer, Barbara and Alexandrov, Ludmil B and Tubio, Jose M. C and Papaemmanuil, Elli and Brewer, Daniel S and Kallio, Heini M. L and Högnäs, Gunilla and Annala, Matti and Kivinummi, Kati and Goody, Victoria and Latimer, Calli and O'Meara, Sarah and Dawson, Kevin J and Isaacs, William and Emmert-Buck, Michael R and Nykter, Matti and Foster, Christopher and Kote-Jarai, Zsofia and Easton, Douglas and Whitaker, Hayley C and Neal, David E and Cooper, Colin S and Eeles, Rosalind A and Visakorpi, Tapio and Campbell, Peter J and McDermott, Ultan and Wedge, David C and Bova, G. Steven and ICGC Prostate UK Grp and ICGC Prostate Group and ICGC Prostate UK Group
Nature, ISSN 0028-0836, 04/2015, Volume 520, Issue 7547, pp. 353 - 357
Cancers emerge from an ongoing Darwinian evolutionary process, often leading to multiple competing subdones within a single primary tumour(1-4). This... 
HETEROGENEITY | PATHOGENESIS | MULTIDISCIPLINARY SCIENCES | PANCREATIC-CANCER | RESISTANCE | PATTERNS | CLONAL EVOLUTION | MUTATIONS | SIGNATURE | PROGRESSION | ANDROGEN DEPRIVATION THERAPY | Prostatic Neoplasms - metabolism | Prostatic Neoplasms - pathology | Epigenesis, Genetic | Humans | Receptors, Androgen - metabolism | Androgens - deficiency | Male | Signal Transduction - genetics | Clone Cells - metabolism | Disease Progression | Neoplasm Metastasis - genetics | Clone Cells - pathology | Prostatic Neoplasms - genetics | DNA Mutational Analysis | Neoplasm Metastasis - pathology | Genes, Tumor Suppressor | Cell Lineage - genetics | Physiological aspects | Metastasis | Prostate cancer | Identification and classification | Mutation
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3. Full Text A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk
by Chandler, Ian and Teixeira, Ana and Howarth, Kimberley and Martin, Lynn and Cazier, Jean-Baptiste and Vijayakrishnan, Jayaram and Houlston, Richard S and Sieber, Oliver and Rowan, Andrew and Wood, Wendy and Tomlinson, Ian and Broderick, Peter and Carvajal-Carmona, Luis and Kemp, Zoe and Sellick, Gabrielle and Peto, Julian and Webb, Emily and Sullivan, Kate and Penegar, Steven and Papaemmanuil, Elli and Fielding, Sarah and Kerr, David and Pittman, Alan M and Barclay, Ella and Gray, Richard and Spain, Sarah and Domingo, Enric and Lubbe, Steven and Gorman, Maggie and Jaeger, Emma and Qureshi, Mobshra and CORGI Consortium and members of the CORGI Consortium
Nature Genetics, ISSN 1061-4036, 11/2007, Volume 39, Issue 11, pp. 1315 - 1317
To identify risk variants for colorectal cancer (CRC), we conducted a genome-wide association study, genotyping 550,163 tag SNPs in 940 individuals with... 
Genetic Predisposition to Disease | Colorectal Neoplasms - genetics | Humans | Risk Factors | Alleles | Genotype | Polymorphism, Single Nucleotide | Genome, Human | Smad7 Protein - genetics | Case-Control Studies | Genetic Linkage | GENETICS & HEREDITY | Colorectal cancer | Physiological aspects | Genetic aspects | Diagnosis | Research | Single nucleotide polymorphisms | Identification and classification | Risk factors | Genetic research | Genotype & phenotype | Genomics
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4. Full Text Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer
by Ju, Young S.eok and Alexandrov, Ludmil B and Gerstung, Moritz and Martincorena, Inigo and Nik-Zainal, Serena and Ramakrishna, Manasa and Davies, Helen R and Papaemmanuil, Elli and Gundem, Gunes and Shlien, Adam and Bolli, Niccolo and Behjati, Sam and Tarpey, Patrick S and Nangalia, Jyoti and Massie, Charles E and Butler, Adam P and Teague, Jon W and Vassiliou, George S and Green, Anthony R and Du, Ming-Qing and Unnikrishnan, Ashwin and Pimanda, John E and Teh, Bin T.ean and Munshi, Nikhil and Greaves, Mel and Vyas, Paresh and El-Naggar, Adel K and Santarius, Tom and Collins, V Peter and Grundy, Richard and Taylor, Jack A and Hayes, D Neil and Malkin, David and Foster, Christopher S and Warren, Anne Y and Whitaker, Hayley C and Brewer, Daniel and Eeles, Rosalind and Cooper, Colin and Neal, David and Visakorpi, Tapio and Isaacs, William B and Bova, G Steven and Flanagan, Adrienne M and Futreal, P Andrew and Lynch, Andy G and Chinnery, Patrick F and McDermott, Ultan and Stratton, Michael R and Campbell, Peter J and ICGC Breast Canc Grp and ICGC Prostate Canc Grp and ICGC Chronic Myeloid Disorders Grp and ICGC Breast Cancer Group and ICGC Chronic Myeloid Disorders Group and ICGC Prostate Cancer Group
eLife, ISSN 2050-084X, 2014, Volume 3
Recent sequencing studies have extensively explored the somatic alterations present in the nuclear genomes of cancers. Although mitochondria control energy... 
evolutionary biology | mitochondrial DNA | genomics | evolution | somatic mutation | cancer genome | human | mutational signature | sequencing | POPULATION-GENETICS | REPLICATION | EVOLUTION | POLYMERASE-GAMMA | ROLES | HETEROPLASMY | BIAS | BIOLOGY | DYNAMICS | PATTERNS | GENOME | Humans | DNA Replication | Data Mining | Neoplasms - classification | Mitochondria - pathology | DNA - genetics | Animals | DNA, Mitochondrial - genetics | Mitochondria - genetics | Neoplasms - genetics | Base Composition | High-Throughput Nucleotide Sequencing | Polymorphism, Single Nucleotide | DNA, Neoplasm - genetics | Genome, Mitochondrial | Mutation | Neoplasms - pathology | Evolution, Molecular | Index Medicus
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5. Full Text Preoperative high respiratory quotient correlates with lower weight loss after bariatric surgery
by Rosales, Armando and Elli, Enrique and Lynch, Scott and Ames, Gretchen and Buchanan, Mauricia and Bowers, Steven P
Surgical endoscopy, ISSN 0930-2794, 09/2019
The respiratory coefficient (RQ), as determined by indirect calorimetry (IC), classifies diet as being carbohydrate rich (RQ = 0.7-0.8), fat rich (RQ =... 
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6. Full Text Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk
by Jaeger, Emma and Webb, Emily and Howarth, Kimberley and Carvajal-Carmona, Luis and Rowan, Andrew and Broderick, Peter and Walther, Axel and Spain, Sarah and Pittman, Alan and Kemp, Zoe and Sullivan, Kate and Heinimann, Karl and Lubbe, Steven and Domingo, Enric and Barclay, Ella and Martin, Lynn and Gorman, Maggie and Chandler, Ian and Vijayakrishnan, Jayaram and Wood, Wendy and Papaemmanuil, Elli and Penegar, Steven and Qureshi, Mobshra and Farrington, Susan and Tenesa, Albert and Cazier, Jean-Baptiste and Kerr, David and Gray, Richard and Peto, Julian and Dunlop, Malcolm and Campbell, Harry and Thomas, Huw and Houlston, Richard and Tomlinson, Ian and CORGI Consortium and members of the CORGI Consortium
Nature Genetics, ISSN 1061-4036, 01/2008, Volume 40, Issue 1, pp. 26 - 28
We mapped a high-penetrance gene (CRAC1; also known as HMPS) associated with colorectal cancer (CRC) in the Ashkenazi population to a 0.6-Mb region on... 
8Q24 | MIXED POLYPOSIS SYNDROME | PROSTATE-CANCER | SUSCEPTIBILITY | GENETICS & HEREDITY | SCAN | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease | Adenoma - genetics | Chromosomes, Human, Pair 15 | Colorectal Neoplasms - genetics | Humans | Cells, Cultured | Cell Line, Tumor | Polymorphism, Single Nucleotide | Jews - genetics | Genetic variation | Colorectal cancer | Physiological aspects | Genetic aspects | Diagnosis | Research | Risk factors | Population genetics | Chromosomes
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7. Full Text Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations
by Intlekofer, Andrew M and Shih, Alan H and Wang, Bo and Nazir, Abbas and Rustenburg, Ariën S and Albanese, Steven K and Patel, Minal and Famulare, Christopher and Correa, Fabian M and Takemoto, Naofumi and Durani, Vidushi and Liu, Hui and Taylor, Justin and Farnoud, Noushin and Papaemmanuil, Elli and Cross, Justin R and Tallman, Martin S and Arcila, Maria E and Roshal, Mikhail and Petsko, Gregory A and Wu, Bin and Choe, Sung and Konteatis, Zenon D and Biller, Scott A and Chodera, John D and Thompson, Craig B and Levine, Ross L and Stein, Eytan M
Nature, ISSN 0028-0836, 07/2018, Volume 559, Issue 7712, pp. 125 - 129
Somatic mutations in the isocitrate dehydrogenase 2 gene (IDH2) contribute to the pathogenesis of acute myeloid leukaemia (AML) through the production of the... 
LUNG-CANCER | CELLS | GEFITINIB | MUTANT IDH2 | MULTIDISCIPLINARY SCIENCES | ACUTE MYELOID-LEUKEMIA | DIFFERENTIATION | (R)-2-HYDROXYGLUTARATE | ENASIDENIB | Triazines - therapeutic use | Humans | Glutarates - blood | Isocitrate Dehydrogenase - antagonists & inhibitors | Aminopyridines - chemistry | Aminopyridines - therapeutic use | Enzyme Inhibitors - chemistry | HEK293 Cells | Protein Multimerization - genetics | Leukemia, Myeloid, Acute - drug therapy | Female | Triazines - chemistry | Mutant Proteins - antagonists & inhibitors | Allosteric Site - genetics | Triazines - pharmacology | Allosteric Site - drug effects | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Mutant Proteins - genetics | Models, Molecular | Isocitrate Dehydrogenase - genetics | Leukemia, Myeloid, Acute - blood | Enzyme Inhibitors - therapeutic use | Disease Progression | Isoleucine - genetics | Drug Resistance, Neoplasm - genetics | Animals | Aminopyridines - pharmacology | Alleles | Glutamine - genetics | Glutarates - metabolism | Mice | Mutation | Clinical Trials, Phase I as Topic | Clinical Trials, Phase II as Topic | Drug Resistance, Neoplasm - drug effects | Leukemia, Myeloid, Acute - genetics | Antimitotic agents | Pharmaceutical research | Research | Drug resistance | Antineoplastic agents | Glutamine | Plasma | Pathogenesis | Leukemia | Lung cancer | Cloning | Neutrophils | Kinases | Cancer therapies | Patients | Proteins | Disease resistance | Allosteric properties | Inhibitors | Bone marrow | Dimers | Inhibition | Target acquisition | Isocitrate dehydrogenase | Isoleucine | Neutropenia | AG-120 | cancer metabolism | leukemia | AG-221 | metabolite | enasidenib | epigenetic | IDH1 | IDH2 | glioma | ivosidenib
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8. Full Text Strategies for surgical remediation of the multi-fundoplication failure patient
by Antiporda, Michael and Antiporda, Michael and Jackson, Chloe and Jackson, Chloe and Smith, C Daniel and Smith, C Daniel and Thomas, Mathew and Thomas, Mathew and Elli, Enrique F and Elli, Enrique F and Bowers, Steven P and Bowers, Steven P
Surgical Endoscopy, ISSN 0930-2794, 5/2019, Volume 33, Issue 5, pp. 1474 - 1481
Outcomes are not well studied in patients undergoing remediation for multi-fundoplication failure, that is, two or more prior failed fundoplications.... 
Medicine & Public Health | Surgery | Gynecology | Hepatology | Gastroenterology | Abdominal Surgery | Laparoscopy | Fundoplication failure | Outcomes | Proctology | SURGERY | FAILED ANTIREFLUX SURGERY | RECONSTRUCTION | PARAESOPHAGEAL HERNIA | ROUX-EN-Y | LAPAROSCOPIC REPAIR | Hernia | Medicine, Experimental | Medical research | Laparoscopic surgery
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9. Full Text Laparoscopic Sleeve Gastrectomy for Morbid Obesity in Patients After Orthotopic Liver Transplant: a Matched Case-Control Study
by Tsamalaidze, Levan and Tsamalaidze, Levan and Stauffer, John A and Stauffer, John A and Arasi, Lisa C and Arasi, Lisa C and Villacreses, Diego E and Villacreses, Diego E and Franco, Jose Salvador Serrano and Franco, Jose Salvador Serrano and Bowers, Steven and Bowers, Steven and Elli, Enrique F and Elli, Enrique F
Obesity Surgery, ISSN 0960-8923, 2/2018, Volume 28, Issue 2, pp. 444 - 450
Obesity is frequently encountered in patients with orthotopic liver transplant (OLT). The role of bariatric surgery is still unclear for this specific... 
Medicine & Public Health | Orthotopic liver transplant | Laparoscopic sleeve gastrectomy | Surgery | Bariatric surgery | SURGERY | FEASIBILITY | RISK | NONALCOHOLIC STEATOHEPATITIS | OUTCOMES | Postoperative Complications - etiology | Obesity, Morbid - surgery | Humans | Middle Aged | Male | Case-Control Studies | Gastrectomy - statistics & numerical data | Operative Time | Laparoscopy - methods | Gastrectomy - methods | Laparoscopy - adverse effects | Gastrectomy - adverse effects | Liver Diseases - complications | Adult | Female | Retrospective Studies | Length of Stay - statistics & numerical data | Body Mass Index | Comorbidity | Postoperative Period | Treatment Outcome | Postoperative Complications - epidemiology | Liver Diseases - epidemiology | Laparoscopy - statistics & numerical data | Obesity, Morbid - complications | Liver Transplantation - statistics & numerical data | Weight Loss | Liver Diseases - surgery | Aged | Obesity, Morbid - epidemiology | Obesity | Medical research | Liver | Medical societies | Body weight | Medicine, Experimental | Laparoscopic surgery | Transplantation | Laparoscopy | Surgical outcomes | Surgical techniques | Transplants & implants | Gastrointestinal surgery
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10. Full Text Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries
by Boer, C and van Duivenvoorde, Y and International Surgical Outcomes Study group and Int Surg Outcomes Study Grp and Region Östergötland and Sinnescentrum and Anestesi- och intensivvårdskliniken US
British Journal of Anaesthesia, ISSN 0007-0912, 11/2016, Volume 117, Issue 5, pp. 601 - 609
As global initiatives increase patient access to surgical treatments, there remains a need to understand the adverse effects of surgery and define appropriate... 
surgical procedures | critical care/utilisation | cohort studies | postoperative care/methods | operative/mortality | postoperative care/statistics and numerical data | surgery | methods | critical care | mortality | postoperative care | statistics and numerical data | operative | utilisation | Critical Care - statistics & numerical data | Poverty | Prospective Studies | Hospital Mortality | Humans | Middle Aged | Elective Surgical Procedures - adverse effects | Male | Treatment Outcome | Postoperative Complications - epidemiology | Socioeconomic Factors | Young Adult | Elective Surgical Procedures - mortality | Adolescent | Global Health - statistics & numerical data | Aged, 80 and over | Adult | Female | Aged | Length of Stay - statistics & numerical data | HOSPITAL MORTALITY | POPULATION | QUALITY | PREVALENCE | FAILURE | SURGICAL-PROCEDURES | INTENSIVE-CARE | MODELING STRATEGY | HIGH-RISK SURGERY | ANESTHESIOLOGY | PROGRAM | Clinical Practice | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | cohort studies; critical care/utilisation; operative/mortality; postoperative care/methods; postoperative care/statistics and numerical data; surgery; surgical procedures | Medicin och hälsovetenskap
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