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Chemical Communications, ISSN 1359-7345, 7/2016, Volume 52, Issue 58, pp. 8935 - 8956
Journal Article
Chemical Communications: Chem Comm, ISSN 1359-7345, 07/2016, Volume 52, Issue 58, pp. 8935 - 8956
Large tumours contain regions with very low intracellular O2 concentrations. Known as hypoxia, this feature of tumours yields a highly reducing environment... 
Reductases | Enzymes | Oxygen | Fluorescence | Hypoxia | Chemoreceptors | Chemical compounds | Tumors
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 06/2014, Volume 20, Issue 24, pp. 7373 - 7380
Journal Article
Chemical Science, ISSN 2041-6520, 2014, Volume 5, Issue 9, pp. 3617 - 3626
The transport of anions across cellular membranes is an important biological function governed by specialised proteins. In recent years, many small molecules... 
SQUARAMIDE | PHOSPHOLIPID FLIP-FLOP | CHOLESTEROL | CHLORIDE TRANSPORT | MOLECULAR RECOGNITION | CONFORMATIONAL CONTROL | MEMBRANES | SELECTIVE RECOGNITION | RECEPTORS | BINDING | CHEMISTRY, MULTIDISCIPLINARY | Proteins | Cellular | Anions | Chlorides | Titration | Biological | Transport
Journal Article
Chemical Communications, ISSN 1359-7345, 3/2015, Volume 51, Issue 24, pp. 4951 - 4968
Anion binding selectivity can often be controlled by judicious arrangement of recognition moieties around an anion of interest. Indeed, nature takes advantage... 
L-PROLINE | SULFATE-BINDING | MOLECULAR RECOGNITION | SELECTIVE RECOGNITION | ALPHA-AMINOXY | BINDING-PROPERTIES | ACTIVE-TRANSPORT | ACID SUBUNITS | CHEMISTRY, MULTIDISCIPLINARY | SYNTHETIC RECEPTOR | AQUEOUS-SOLUTION | Binding | Residues | Anions | Receptors | Peptides | Amino acids | Scaffolds | Recognition
Journal Article
Organic Letters, ISSN 1523-7060, 11/2013, Volume 15, Issue 22, pp. 5638 - 5641
The synthesis and photophysical properties of four squaramide based fluorescent anion sensors (1–4) are described. These luminescent compounds showed... 
FLUORESCENT PET SENSORS | SQUARAMIDE | AQUEOUS-MEDIA | CHEMISTRY, ORGANIC | SELECTIVE RECOGNITION | CLEFT-LIKE | RECEPTOR | ANION RECOGNITION | BINDING | CYCLIC-PEPTIDES | UREA
Journal Article
Chemical Communications, ISSN 1359-7345, 03/2012, Volume 48, Issue 20, pp. 2588 - 2590
Journal Article
Chemical Science, ISSN 2041-6520, 2016, Volume 7, Issue 7, pp. 4563 - 4572
A number of macrocyclic squaramide-containing receptors (MSQs) have been designed and synthesised and their interaction with a range of inorganic anions was... 
FLUORESCENT | PROTEIN | RECOGNITION | ARMS | EXCHANGE | CHEMISTRY, MULTIDISCIPLINARY | CHLORIDE | WATER
Journal Article
Chemical Communications, ISSN 1359-7345, 05/2015, Volume 51, Issue 50, pp. 10107 - 10110
An oxothiosquaramide was shown to bind to chloride through hydrogen bonding interactions in DMSO and found to exhibit pH switchable choride transport across... 
AFFINITY | CARRIERS | BINDING | CHEMISTRY, MULTIDISCIPLINARY | Biological Transport | Hydrogen Bonding | Chlorides - metabolism | Dimethyl Sulfoxide - chemistry | Thiones - chemistry | Chlorides - chemistry | Cyclobutanes - chemistry | Lipid Bilayers - metabolism | Biomimetic Materials - chemistry | Hydrogen-Ion Concentration
Journal Article
Chemical Communications, ISSN 1359-7345, 2018, Volume 54, Issue 61, pp. 8466 - 8469
Traditionally, fluorescence probes have focused on the detection of a single biomarker for a specific process. In this work, we set out to develop a number of... 
NITRIC-OXIDE | CELLS | FLUOROGENIC PROBE | PEROXYNITRITE | GLUTATHIONE | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Chemical communications (Cambridge, England), ISSN 1359-7345, 01/2011, Volume 47, Issue 2, pp. 686 - 688
The quaternarized pdppz derivative 1 was shown to bind strongly to DNA with concomitant changes in its ground and excited state photophysical properties.... 
DNA - chemistry | Humans | Light | Cell Line, Tumor | Circular Dichroism | Coordination Complexes - chemistry | Coordination Complexes - toxicity | Apoptosis | Drug Screening Assays, Antitumor
Journal Article
Chemical Communications, ISSN 1359-7345, 2015, Volume 51, Issue 24, pp. 4951 - 4968
Anion binding selectivity can often be controlled by judicious arrangement of recognition moieties around an anion of interest. Indeed, nature takes advantage... 
Journal Article
Journal Article
Nanoscale, ISSN 2040-3364, 01/2016, Volume 8, Issue 1, pp. 563 - 574
The development of Ru(II) functionalized gold nanoparticles 1–3·AuNP is described. These systems were found to be mono-disperse with a hydrodynamic radius of... 
Gold - chemistry | Neoplasms - metabolism | Optical Imaging | DNA, Neoplasm - metabolism | Humans | Metal Nanoparticles - chemistry | Gold - pharmacology | Ruthenium - chemistry | Ruthenium - pharmacology | Neoplasms - drug therapy | HeLa Cells | Neoplasms - pathology | Metal Nanoparticles - ultrastructure
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, p. e94200
The endocannabinoid anandamide (AEA) is an antinociceptive lipid that is inactivated through cellular uptake and subsequent catabolism by fatty acid amide... 
MOUSE-BRAIN | AMIDE HYDROLASE | ACTIVATED-RECEPTOR-ALPHA | COST-EFFECTIVENESS | CANNABINOID RECEPTOR | MULTIPLE-SCLEROSIS | NUCLEAR RECEPTORS | MULTIDISCIPLINARY SCIENCES | ATHEROSCLEROSIS | INFLAMMATORY PAIN | MICE | Endocannabinoids - metabolism | Analgesics - pharmacology | Fatty Acid-Binding Proteins - antagonists & inhibitors | Molecular Conformation | Neuralgia - metabolism | Analgesics - metabolism | Male | Fatty Acid-Binding Proteins - metabolism | Brain - metabolism | Arachidonic Acids - metabolism | Disease Models, Animal | Hyperalgesia - metabolism | Models, Molecular | Rats | Polyunsaturated Alkamides - metabolism | Neuralgia - drug therapy | Analgesia | Receptor, Cannabinoid, CB1 - metabolism | Animals | Hyperalgesia - drug therapy | Analgesics - chemistry | Protein Binding | Fatty Acid-Binding Proteins - chemistry | Mice | Molecular Docking Simulation | PPAR alpha - metabolism | Analgesics | Analysis | Physiological aspects | Binding proteins | Fatty acids | Health aspects | Protein binding | Brain | Animal models | Multiple sclerosis | Substance abuse treatment | Biochemistry | Biology | Neuropathy | Proteins | Pain | Chloride | Inhibition | Fatty-acid amide hydrolase | Enzymes | Pain perception | Hydrolase | Pharmacology | Inflammation | Cannabinoid CB1 receptors | Anandamide | Chemistry | Inhibitors | Fatty acid-binding protein | Affinity | Catabolism | Anesthesiology | Cost analysis | Laboratory animals
Journal Article