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index medicus (230) 230
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adenosine receptors (23) 23
induced vascular leak (23) 23
inflammation - metabolism (23) 23
receptor, adenosine a2b - genetics (22) 22
receptor, adenosine a2b - metabolism (22) 22
reperfusion injury (22) 22
signal transduction - physiology (22) 22
cardiac & cardiovascular systems (21) 21
gene expression (21) 21
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proteins (21) 21
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biology (20) 20
hypoxia-inducible factor 1, alpha subunit - metabolism (20) 20
physiology (20) 20
hypoxia - metabolism (19) 19
medicine, general & internal (19) 19
multidisciplinary sciences (19) 19
reperfusion (19) 19
respiratory-distress-syndrome (19) 19
aged (18) 18
echocardiography, transesophageal (18) 18
medicine (18) 18
adult (17) 17
activation (16) 16
cell line (16) 16
cells (16) 16
extracellular adenosine (16) 16
hematology (16) 16
hif-1-dependent repression (16) 16
hypoxia-inducible factor 1, alpha subunit - genetics (16) 16
inflammatory bowel disease (16) 16
metabolism (16) 16
receptor, adenosine a2b - physiology (16) 16
nucleotide phosphohydrolysis (15) 15
research article (15) 15
tissue-damage (15) 15
acute lung injury - metabolism (14) 14
dependent induction (14) 14
expression (14) 14
gene expression regulation (14) 14
hypoxia - physiopathology (14) 14
ischemia/reperfusion injury (14) 14
5'-nucleotidase - metabolism (13) 13
analysis (13) 13
mice, transgenic (13) 13
reverse transcriptase polymerase chain reaction (13) 13
5'-nucleotidase - genetics (12) 12
adenosine - physiology (12) 12
biomedicine (12) 12
cd73 (12) 12
factor-i (12) 12
inflammation - pathology (12) 12
protection (12) 12
respiratory tract diseases (12) 12
science (12) 12
acute kidney injury (11) 11
adenosine receptor (11) 11
diagnosis (11) 11
disease (11) 11
gastroenterology & hepatology (11) 11
gene-expression (11) 11
health aspects (11) 11
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1. Full Text MECHANISMS OF DISEASE Purinergic Signaling during Inflammation
by Eltzschig, HK and Sitkovsky, MV and Robson, SC
NEW ENGLAND JOURNAL OF MEDICINE, ISSN 0028-4793, 12/2012, Volume 367, Issue 24, pp. 2322 - 2333
  Receptors for ATP and ADP and adenosine exert various effects. ATP and ADP signaling is mainly proinflammatory, and adenosine signaling is mainly... 
ISCHEMIA-REPERFUSION INJURY | ECTO-5'-NUCLEOTIDASE CD73 | MEDICINE, GENERAL & INTERNAL | ISCHEMIA/REPERFUSION INJURY | INDUCED VASCULAR LEAK | A2B ADENOSINE RECEPTOR | INDUCIBLE FACTOR-I | EXPERIMENTAL COLITIS | ACUTE LUNG INJURY | ATP RELEASE | T-CELLS | Proteins | Disease | Ischemia | Rodents | Ligands | Asthma | Apoptosis
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2. Full Text Cardioprotection by ecto-5′-nucleotidase (CD73) and A2B adenosine receptors
by Eckle, Tobias and Krahn, Thomas and Grenz, Almut and Köhler, David and Mittelbronn, Michel and Ledent, Catherine and Jacobson, Marlene A and Osswald, Hartmut and Thompson, Linda F and Unertl, Klaus and Eltzschig, Holger K
Circulation, ISSN 0009-7322, 2007, Volume 115, Issue 12, pp. 1581 - 1590
Ecto-5'-nucleotidase (CD73)-dependent adenosine generation has been implicated in tissue protection during acute injury. Once generated, adenosine can activate... 
Nucleotidase | Adenosine | Infarction | Reperfusion | Ischemia | 5'-Nucleotidase - genetics | Myocardial Ischemia - metabolism | Up-Regulation | Receptor, Adenosine A2B - biosynthesis | Male | Receptor, Adenosine A2B - genetics | 5'-Nucleotidase - deficiency | Xanthines - pharmacology | Cardiotonic Agents - therapeutic use | Aminopyridines - therapeutic use | Myocardial Infarction - pathology | Receptor, Adenosine A2B - drug effects | Female | Receptor, Adenosine A2B - physiology | Drug Evaluation, Preclinical | Receptor, Adenosine A2B - deficiency | Mice, Inbred C57BL | Neutrophils | Cardiotonic Agents - pharmacology | Myocardial Ischemia - drug therapy | Mice, Knockout | Extracellular Fluid - metabolism | Animals | Ischemic Preconditioning, Myocardial | Adenosine - physiology | Aminopyridines - pharmacology | 5'-Nucleotidase - physiology | Xanthines - toxicity | Mice | Cell Hypoxia - genetics | Prevention | Care and treatment | Physiological aspects | Myocardial ischemia | Research | Nucleotidases | Index Medicus | Abridged Index Medicus
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3. Full Text The authors reply
by Eltzschig, Holger K and Sitkovsky, Michail V and Robson, Simon C
New England Journal of Medicine, ISSN 0028-4793, 03/2013, Volume 368, Issue 13, p. 1260
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4. Full Text Hypoxia-inducible factor-1α-dependent protection from intestinal ischemia/reperfusion injury involves ecto-59-nucleotidase (CD73) and the A2B adenosine receptor
by Hart, Melanie L and Grenz, Almut and Gorzolla, Iris C and Schittenhelm, Jens and Dalton, Julee H and Eltzschig, Holger K
Journal of Immunology, ISSN 0022-1767, 04/2011, Volume 186, Issue 7, pp. 4367 - 4374
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5. Full Text Perioperative Management of Disruptive Patients
by Berg, Nathaniel K and Eltzschig, Holger K and Vanga, Naveen and Love, Latanya J and Nwokolo, Omonele O
Anesthesia and analgesia, ISSN 0003-2999, 01/2019, p. 1
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6. Full Text HIF-l-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak
by Morote-Garcia, Julio C and Rosenberger, Peter and Kuhlicke, Johannes and Eltzschig, Holger K
Blood, ISSN 0006-4971, 06/2008, Volume 111, Issue 12, pp. 5571 - 5580
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7. Full Text Letter of retraction
by Hart, Melanie L and Gorzolla, Iris C and Schittenhelm, Jens and Dalton, Julee H and Eltzschig, Holger K
Journal of Immunology, ISSN 0022-1767, 09/2017, Volume 199, Issue 5, p. 1942
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8. Full Text Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: Role of ectonucleotidases and adenosine A 2B receptors
by Eltzschig, Holger K and Ibla, Juan C and Furuta, Glenn T and Leonard, Martin O and Jacobson, Kenneth A and Enjyoji, Keiichi and Robson, Simon C and Colgan, Sean R
Journal of Experimental Medicine, ISSN 0022-1007, 09/2003, Volume 198, Issue 5, pp. 783 - 796
Adenosine | Ectonucleotidase | Inflammation | Neutrophil | Endothelium
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9. Full Text Hydroxylation-independent HIF-1a stabilization through PKA: A new paradigm for hypoxia signaling
by Mcnamee, Eóin N and Vohwinkel, Christine and Eltzschig, Holger K
Science Signaling, ISSN 1945-0877, 05/2016, Volume 9, Issue 430
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10. Full Text Protective role of ecto-5′-nucleiotidase (CD73) in renal ischemia
by Grenz, Almut and Zhang, Hua and Eckle, Tobias and Mittelbronn, Michel and Wehrmann, Manfred and Köhle, Christoph and Kloor, Doris and Thompson, Linda F and Osswald, Hartmut and Eltzschig, Holger K
Journal of the American Society of Nephrology, ISSN 1046-6673, 2007, Volume 18, Issue 3, pp. 833 - 845
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11. Full Text Hypoxia-inducible factors as molecular targets for liver diseases
by Ju, Cynthia and Colgan, Sean P and Eltzschig, Holger K
Journal of molecular medicine (Berlin, Germany), 06/2016, Volume 94, Issue 6, p. 613
Liver disease is a growing global health problem, as deaths from end-stage liver cirrhosis and cancer are rising across the world. At present, pharmacologic... 
Bevacizumab - therapeutic use | Oligonucleotides - therapeutic use | Fatty Liver - pathology | Humans | Fatty Liver - therapy | Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Hepatitis, Viral, Human - genetics | Liver Neoplasms - therapy | Molecular Targeted Therapy | Liver Diseases, Alcoholic - genetics | Liver Diseases, Alcoholic - therapy | Basic Helix-Loop-Helix Transcription Factors - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Carcinoma, Hepatocellular - genetics | Liver Cirrhosis - metabolism | Liver Neoplasms - pathology | Liver Cirrhosis - genetics | Fatty Liver - genetics | Liver Diseases, Alcoholic - pathology | Basic Helix-Loop-Helix Transcription Factors - genetics | Fatty Liver - metabolism | Liver Neoplasms - genetics | Signal Transduction | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Hepatitis, Viral, Human - therapy | Gene Expression Regulation | Basic Helix-Loop-Helix Transcription Factors - antagonists & inhibitors | Clinical Trials as Topic | Liver Cirrhosis - therapy | Liver Diseases, Alcoholic - metabolism | Hepatitis, Viral, Human - pathology | Animals | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Hepatitis, Viral, Human - metabolism | Liver Cirrhosis - pathology | Carcinoma, Hepatocellular - therapy | Carcinoma, Hepatocellular - metabolism
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12. Full Text Hydroxylation-independent HIF-1[alpha] stabilization through PKA: A new paradigm for hypoxia signaling
by McNamee, Eoin N and Vohwinkel, Christine and Eltzschig, Holger K
Science Signaling, ISSN 1945-0877, 05/2016, Volume 9, Issue 430, pp. fs11 - fs11
In this issue of Science Signaling, Bullen et al. demonstrate that protein kinase A (PKA) phosphorylates and stimulates the transcriptional activity of... 
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13. Full Text Correction: Detrimental ELAVL-1/HuR-dependent GSK3[beta] mRNA stabilization impairs resolution in acute respiratory distress syndrome
by Hoffman, Olivia and Burns, Nana and Vadasz, Istvan and Eltzschig, Holger K and Edwards, Michael G and Vohwinkel, Christine U
PLoS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, p. e0176134
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14. Full Text Sa1762 Epithelial Netrin-1 Controls CD4 Th1 T-Cell Trafficking to the Inflamed Intestine
by Aherne, Carol and Collins, Colm and McNamee, Eoin N and Eltzschig, Holger K
Gastroenterology, ISSN 0016-5085, 2015, Volume 148, Issue 4, pp. S-325 - S-325
Gastroenterology and Hepatology | T cells
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15. Full Text Detrimental ELAVL-1/HuR-dependent GSK3[beta] mRNA stabilization impairs resolution in acute respiratory distress syndrome
by Hoffman, Olivia and Burns, Nana and Vadasz, Istvan and Eltzschig, Holger K and Edwards, Michael G and Vohwinkel, Christine U
PLoS ONE, ISSN 1932-6203, 02/2017, Volume 12, Issue 2, p. e0172116
A hallmark of acute respiratory distress syndrome (ARDS) is accumulation of protein-rich edema in the distal airspaces and its removal is critical for patient... 
Messenger RNA | Respiratory distress syndrome | Physiological aspects | Genetic aspects | Research | Protein kinases | Risk factors
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16. Full Text The authors reply
by Eltzschig, Holger K and Carmeliet, Peter
New England Journal of Medicine, ISSN 0028-4793, 05/2011, Volume 364, Issue 20, p. 1977
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17. Full Text TnT: Blowing the Cover from Perioperative Myocardial Injury
by Bartels, Karsten and Sullivan, Breandan L and Eltzschig, Holger K
Anesthesiology, ISSN 0003-3022, 03/2014, Volume 120, Issue 3, pp. 533 - 535
SURGERY | ANESTHESIOLOGY | TRANSESOPHAGEAL ECHOCARDIOGRAPHY | Surgical Procedures, Operative | Humans | Male | Postoperative Complications - epidemiology | Patient Outcome Assessment | Myocardial Ischemia - diagnosis | Postoperative Complications - diagnosis | Myocardial Ischemia - epidemiology | Index Medicus | Abridged Index Medicus
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18. Full Text Erratum: Corrigendum: Hypoxia-inducible factor–dependent induction of netrin-1 dampens inflammation caused by hypoxia
by Rosenberger, Peter and Schwab, Jan M and Mirakaj, Valbona and Masekowsky, Eva and Mager, Alice and Morote-Garcia, Julio C and Unertl, Klaus and Eltzschig, Holger K
Nature Immunology, ISSN 1529-2908, 05/2015, Volume 16, Issue 5, pp. 544 - 544
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19. Full Text Extracellular adenosine signaling in molecular medicine
by Eltzschig, Holger K
Journal of Molecular Medicine, ISSN 0946-2716, 2/2013, Volume 91, Issue 2, pp. 141 - 146
  Issue Title: Extracellular adenosine signaling in molecular medicine 
Human Genetics | Internal Medicine | Molecular Medicine | Biomedicine | ISCHEMIA-REPERFUSION INJURY | MEDICINE, RESEARCH & EXPERIMENTAL | ACUTE KIDNEY INJURY | EXPERIMENTAL COLITIS | PROTECTION | HIF-1-DEPENDENT REPRESSION | INFLAMMATION | GENETICS & HEREDITY | ACUTE LUNG INJURY | ATP RELEASE | HYPOXIA | T-CELLS | Animals | Signal Transduction | Adenosine - physiology | Humans | Index Medicus | CD73 | colitis | AMP | ENT1 | ENT2 | hypoxia-inducible factor | ecto-nucleotidase | acute lung injury | inflammatory bowel disease | ischemia | adenosine | A2A | A2B | equilibrative nucleoside transporters | adenosine kinase | apyrase | adenosine deaminase | CD39 | cancer | ATP | sepsis
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20. Full Text Hypoxia and inflammation are two sides of the same coin
by Karsten Bartels and Almut Grenz and Holger K. Eltzschig
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2013, Volume 110, Issue 46, pp. 18351 - 18352
COMMENTARIES | Oxygen | Antiinflammatories | Ischemia | Genes | Gastroenterology | Anaerobic conditions | Hypoxia | Inflammation | Colitis | Intestinal diseases | DEPENDENT INDUCTION | INHIBITION | INDUCIBLE FACTOR-I | COLITIS | MULTIDISCIPLINARY SCIENCES | ISCHEMIA | MECHANISMS | NF-KAPPA-B | Humans | Gene Expression Regulation - physiology | Hypoxia - physiopathology | Mixed Function Oxygenases - metabolism | NF-kappa B - metabolism | Signal Transduction - physiology | Inflammation - physiopathology | Index Medicus | Biological Sciences | Commentaries
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