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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2014, Volume 111, Issue 48, pp. 17266 - 17271
Although initially responsive to chemotherapy, many patients with ovarian cancer subsequently develop relapsed and potentially fatal metastatic disease, which... 
Stem cells | Cell lines | Mice | Cellular immunity | Signatures | Spheroids | Heterologous transplantation | Tumors | Ovarian cancer | Cancer | PDX mice model | Ovarian cancer stem cell | ROR1 | Monoclonal antibody | SURVIVAL | ovarian cancer stem cell | SIDE POPULATION | GYNECOLOGIC-ONCOLOGY-GROUP | ALDEHYDE DEHYDROGENASE | MULTIDISCIPLINARY SCIENCES | DRUG-RESISTANCE | STAGE-III | CHEMOTHERAPY | EPITHELIAL-MESENCHYMAL TRANSITION | monoclonal antibody | HUMAN TUMORS | CD133 | Prognosis | Humans | Gene Expression Regulation, Neoplastic | Immunoblotting | Transplantation, Heterologous | Gene Expression Profiling | Ovarian Neoplasms - genetics | Neoplastic Stem Cells - metabolism | RNA Interference | Neoplastic Stem Cells - pathology | Female | Ovarian Neoplasms - metabolism | Spheroids, Cellular - drug effects | Antibodies, Monoclonal - immunology | Molecular Targeted Therapy - methods | Ovarian Neoplasms - prevention & control | Receptor Tyrosine Kinase-like Orphan Receptors - metabolism | Antibodies, Monoclonal - pharmacology | Spheroids, Cellular - metabolism | Kaplan-Meier Estimate | Receptor Tyrosine Kinase-like Orphan Receptors - immunology | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Microscopy, Confocal | Animals | Cell Line, Tumor | Mice, Inbred NOD | Receptor Tyrosine Kinase-like Orphan Receptors - genetics | Care and treatment | Oncology, Experimental | Transplantation | Research | Gene expression | Stem cell research | Cancer cells | Genetic aspects | Health aspects | Methods | Biological Sciences
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2017, Volume 114, Issue 40, p. 10731
Journal Article
Journal Article
PLoS Computational Biology, ISSN 1553-734X, 03/2015, Volume 11, Issue 3
Mutations in the splicing factor SF3B1 are found in several cancer types and have been associated with various splicing defects. Using transcriptome sequencing... 
Studies | Breast cancer | Mutation | Genes | Leukemia
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2014, Volume 111, Issue 2, p. 793
  Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is an oncoembryonic antigen found on chronic lymphocytic leukemia (CLL) B cells, but not on normal... 
Proteins | Therapy | Rodents | Immune system
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2015, Volume 112, Issue 14, p. 4322
  Immunoglobulins (Ig) are produced by B lymphocytes as secreted antibodies or as part of the B-cell receptor. There is tremendous diversity of potential Ig... 
Maturation | Leukemia | Genes | Mutation | Ribonucleic acid--RNA
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 01/2014, Volume 111, Issue 2, pp. 793 - 798
Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is a type 1 protein expressed on chronic lymphocytic leukemia (CLL) B cells, but not on normal... 
Biological Sciences | immune therapy | AKT | mouse model | monoclonal antibody
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2014, Volume 111, Issue 48, p. 17266
  Although initially responsive to chemotherapy, many patients with ovarian cancer subsequently develop relapsed and potentially fatal metastatic disease,... 
Rodents | Stem cells | Cancer therapies | Ovarian cancer | Tumors
Journal Article
Cancer Cell, ISSN 1535-6108, 11/2016, Volume 30, Issue 5, pp. 750 - 763
Journal Article
BLOOD, ISSN 0006-4971, 07/2014, Volume 124, Issue 4, pp. 546 - 554
Journal Article
Haematologica, ISSN 0390-6078, 07/2015, Volume 100, Issue 7, pp. 945 - 954
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 1853 - 1853
Abstract An integrated analysis of transcriptomic signatures applied to almost 12,000 primary human tumors of 33 different cancer types from The Cancer Genome... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 3122 - 3122
Abstract Recent studies have linked the autophagy adaptor p62/SQSTM1 to tumorigenesis via NRF2 signaling. Increased accumulation p62 is associated with disease... 
Journal Article