PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, p. e32524
The circumsporozoite protein (CSP) plays a key role in malaria sporozoite infection of both mosquito salivary glands and the vertebrate host. The conserved...
MULTIDISCIPLINARY SCIENCES | CELL INVASION | ANOPHELES-STEPHENSI | MALARIA PARASITE | HEPARAN-SULFATE PROTEOGLYCANS | AEDES-AEGYPTI | SALIVARY-GLANDS | MONOCLONAL-ANTIBODIES | PROTECTIVE ANTIBODIES | FALCIPARUM SPOROZOITES | II-PLUS | Protein Structure, Tertiary | Amino Acid Sequence | Animals, Genetically Modified | Molecular Sequence Data | Sequence Homology, Amino Acid | Plasmodium berghei - metabolism | Animals | Protozoan Proteins - metabolism | Microscopy, Fluorescence - methods | Culicidae | Sporozoites | Female | Protozoan Proteins - chemistry | Epitopes - chemistry | Mice | Mice, Inbred BALB C | Transgenes | Infection | Amino acids | Genetic engineering | Genetic aspects | Malaria | Health aspects | Motility | Peptides | Midgut | Glands | Transgenic | Homology | Vaccines | Parasites | Aquatic insects | Proteins | CS gene | Proteolysis | Infectivity | Rodents | Life sciences | Localization | Circumsporozoite protein | Vector-borne diseases | Antigens | Immunoglobulins | Salivary glands | Mammals | Medicine | Mosquitoes | Adhesives | Immunogenicity | Immunofluorescence
MULTIDISCIPLINARY SCIENCES | CELL INVASION | ANOPHELES-STEPHENSI | MALARIA PARASITE | HEPARAN-SULFATE PROTEOGLYCANS | AEDES-AEGYPTI | SALIVARY-GLANDS | MONOCLONAL-ANTIBODIES | PROTECTIVE ANTIBODIES | FALCIPARUM SPOROZOITES | II-PLUS | Protein Structure, Tertiary | Amino Acid Sequence | Animals, Genetically Modified | Molecular Sequence Data | Sequence Homology, Amino Acid | Plasmodium berghei - metabolism | Animals | Protozoan Proteins - metabolism | Microscopy, Fluorescence - methods | Culicidae | Sporozoites | Female | Protozoan Proteins - chemistry | Epitopes - chemistry | Mice | Mice, Inbred BALB C | Transgenes | Infection | Amino acids | Genetic engineering | Genetic aspects | Malaria | Health aspects | Motility | Peptides | Midgut | Glands | Transgenic | Homology | Vaccines | Parasites | Aquatic insects | Proteins | CS gene | Proteolysis | Infectivity | Rodents | Life sciences | Localization | Circumsporozoite protein | Vector-borne diseases | Antigens | Immunoglobulins | Salivary glands | Mammals | Medicine | Mosquitoes | Adhesives | Immunogenicity | Immunofluorescence
Journal Article
Cell Biochemistry and Function, ISSN 0263-6484, 12/2016, Volume 34, Issue 8, pp. 620 - 627
Glyoxalase II, the second of 2 enzymes in the glyoxalase system, is a hydroxyacylglutathione hydrolase that catalyses the hydrolysis of S‐d‐lactoylglutathione...
actin protein | MDH protein | glutathione | glutathionylation | glyoxalase system | S‐d‐lactoylglutathione | Glyoxalase II | post‐translational modification (PTM) | post-translational modification (PTM) | S-d-lactoylglutathione | OXIDATIVE STRESS | COMPLEX | ACTIN | MACROMOLECULES | MALATE-DEHYDROGENASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYSTEINE | CELL BIOLOGY | ENZYME | PURIFICATION | LIVER | BINDING | Malate Dehydrogenase - metabolism | Glutathione - metabolism | Computer Simulation | Humans | Actins - metabolism | Glutathione - chemistry | Molecular Docking Simulation | Thiolester Hydrolases - metabolism | Thiolester Hydrolases - chemistry | Antioxidants | Post-translational modification | Hydrolysis | Enzymes | Thiols | Actin | Hydrolases | Muscle proteins | Proteins | Dehydrogenases
actin protein | MDH protein | glutathione | glutathionylation | glyoxalase system | S‐d‐lactoylglutathione | Glyoxalase II | post‐translational modification (PTM) | post-translational modification (PTM) | S-d-lactoylglutathione | OXIDATIVE STRESS | COMPLEX | ACTIN | MACROMOLECULES | MALATE-DEHYDROGENASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYSTEINE | CELL BIOLOGY | ENZYME | PURIFICATION | LIVER | BINDING | Malate Dehydrogenase - metabolism | Glutathione - metabolism | Computer Simulation | Humans | Actins - metabolism | Glutathione - chemistry | Molecular Docking Simulation | Thiolester Hydrolases - metabolism | Thiolester Hydrolases - chemistry | Antioxidants | Post-translational modification | Hydrolysis | Enzymes | Thiols | Actin | Hydrolases | Muscle proteins | Proteins | Dehydrogenases
Journal Article
Human Psychopharmacology: Clinical and Experimental, ISSN 0885-6222, 07/2014, Volume 29, Issue 4, pp. 388 - 391
Objective During the last few years, an increasing number of studies have focused on the association between neuroplasticity and affective disorders. The aim...
BDNF | ST8SIA2 | stressful life events | antidepressant | VARIANTS | PSYCHIATRY | MAJOR DEPRESSION | POLYMORPHISM | CLINICAL NEUROLOGY | PSYCHOLOGY | NEUROTROPHIC FACTOR GENE | MOOD DISORDERS | PHARMACOLOGY & PHARMACY | FACTOR BDNF GENE | ASSOCIATION | EXPRESSION | ONSET | Haplotypes | Brain-Derived Neurotrophic Factor - genetics | Mood Disorders - drug therapy | Mood Disorders - genetics | Humans | Life Change Events | Middle Aged | Sialyltransferases - genetics | Male | Treatment Outcome | Gene-Environment Interaction | Antidepressive Agents - therapeutic use | Time Factors | Anxiety Disorders - genetics | Female | Heterozygote | Polymorphism, Single Nucleotide | Anxiety Disorders - drug therapy | Genetic research | Anxiety | Single nucleotide polymorphisms | Antidepressants | Analysis | Genes
BDNF | ST8SIA2 | stressful life events | antidepressant | VARIANTS | PSYCHIATRY | MAJOR DEPRESSION | POLYMORPHISM | CLINICAL NEUROLOGY | PSYCHOLOGY | NEUROTROPHIC FACTOR GENE | MOOD DISORDERS | PHARMACOLOGY & PHARMACY | FACTOR BDNF GENE | ASSOCIATION | EXPRESSION | ONSET | Haplotypes | Brain-Derived Neurotrophic Factor - genetics | Mood Disorders - drug therapy | Mood Disorders - genetics | Humans | Life Change Events | Middle Aged | Sialyltransferases - genetics | Male | Treatment Outcome | Gene-Environment Interaction | Antidepressive Agents - therapeutic use | Time Factors | Anxiety Disorders - genetics | Female | Heterozygote | Polymorphism, Single Nucleotide | Anxiety Disorders - drug therapy | Genetic research | Anxiety | Single nucleotide polymorphisms | Antidepressants | Analysis | Genes
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2018, Volume 13, Issue 8, p. e0201371
Background For many years, long-acting intramuscular (LAI) antipsychotics have been prescribed predominantly to chronic and severe patients, as a last resort...
1ST EPISODE | COMPARATIVE EFFICACY | NEGATIVE SYMPTOMS | MULTIDISCIPLINARY SCIENCES | INJECTABLE ANTIPSYCHOTICS | SCHIZOPHRENIA | DEPOT ANTIPSYCHOTICS | INJECTIONS | PATIENT | ORAL ANTIPSYCHOTICS | ATTITUDES | Schizophrenia | Bipolar disorder | Usage | Care and treatment | Prescription writing | Antipsychotic drugs | Health sciences | Neurosciences | Substance abuse treatment | Neuroleptics | Mental disorders | Comorbidity | Mental health | Systematic review | Regression analysis | Aripiprazole | Males | Metabolism | Patients | Training | Psychotropic drugs | Hospitals | Maternal & child health | Surgery | Diagnosis | Risperidone | Psychiatry | Drug use
1ST EPISODE | COMPARATIVE EFFICACY | NEGATIVE SYMPTOMS | MULTIDISCIPLINARY SCIENCES | INJECTABLE ANTIPSYCHOTICS | SCHIZOPHRENIA | DEPOT ANTIPSYCHOTICS | INJECTIONS | PATIENT | ORAL ANTIPSYCHOTICS | ATTITUDES | Schizophrenia | Bipolar disorder | Usage | Care and treatment | Prescription writing | Antipsychotic drugs | Health sciences | Neurosciences | Substance abuse treatment | Neuroleptics | Mental disorders | Comorbidity | Mental health | Systematic review | Regression analysis | Aripiprazole | Males | Metabolism | Patients | Training | Psychotropic drugs | Hospitals | Maternal & child health | Surgery | Diagnosis | Risperidone | Psychiatry | Drug use
Journal Article
Journal of Neuro-Oncology, ISSN 0167-594X, 10/2015, Volume 125, Issue 1, pp. 223 - 224
Journal Article
Journal of Neuro-Oncology, ISSN 0167-594X, 5/2016, Volume 128, Issue 1, pp. 157 - 162
The role of temozolomide concurrent with and adjuvant to radiotherapy (RT/TMZ) in elderly patients with glioblastoma (GBM) remains unclear. We evaluated the...
Neurology | Medicine & Public Health | MGMT methylation | Glioblastoma | Oncology | Temozolomide | Radiotherapy | Elderly | ONCOLOGY | CONCOMITANT | OLDER | CLINICAL NEUROLOGY | RADIATION-THERAPY | ADJUVANT | Promoter Regions, Genetic | Prospective Studies | Dacarbazine - therapeutic use | Humans | Brain Neoplasms - pathology | DNA Repair Enzymes - genetics | Brain Neoplasms - drug therapy | Glioblastoma - radiotherapy | Brain Neoplasms - surgery | Glioblastoma - surgery | Antineoplastic Agents, Alkylating - therapeutic use | DNA Methylation | DNA Modification Methylases - genetics | Glioblastoma - pathology | Tumor Suppressor Proteins - genetics | Dacarbazine - analogs & derivatives | Survival Analysis | Aged, 80 and over | Aged | Brain Neoplasms - radiotherapy | Glioblastoma - drug therapy | Antimitotic agents | Medical research | Analysis | Medicine, Experimental | Methylation | Antineoplastic agents | Glioblastoma multiforme
Neurology | Medicine & Public Health | MGMT methylation | Glioblastoma | Oncology | Temozolomide | Radiotherapy | Elderly | ONCOLOGY | CONCOMITANT | OLDER | CLINICAL NEUROLOGY | RADIATION-THERAPY | ADJUVANT | Promoter Regions, Genetic | Prospective Studies | Dacarbazine - therapeutic use | Humans | Brain Neoplasms - pathology | DNA Repair Enzymes - genetics | Brain Neoplasms - drug therapy | Glioblastoma - radiotherapy | Brain Neoplasms - surgery | Glioblastoma - surgery | Antineoplastic Agents, Alkylating - therapeutic use | DNA Methylation | DNA Modification Methylases - genetics | Glioblastoma - pathology | Tumor Suppressor Proteins - genetics | Dacarbazine - analogs & derivatives | Survival Analysis | Aged, 80 and over | Aged | Brain Neoplasms - radiotherapy | Glioblastoma - drug therapy | Antimitotic agents | Medical research | Analysis | Medicine, Experimental | Methylation | Antineoplastic agents | Glioblastoma multiforme
Journal Article
Journal of Neuro-Oncology, ISSN 0167-594X, 1/2018, Volume 136, Issue 1, pp. 221 - 222
The members of the PERNO Study Group were not individually captured in the metadata of the original publication. They are included in the metadata of this...
Medicine & Public Health | Neurology | Oncology | Antimitotic agents | Neurosciences | Aged | Radiotherapy | Antineoplastic agents | Metadata | Temozolomide | Radiation therapy | Glioblastoma | Geriatrics
Medicine & Public Health | Neurology | Oncology | Antimitotic agents | Neurosciences | Aged | Radiotherapy | Antineoplastic agents | Metadata | Temozolomide | Radiation therapy | Glioblastoma | Geriatrics
Journal Article
Human Psychopharmacology: Clinical and Experimental, ISSN 0885-6222, 07/2014, Volume 29, Issue 4, pp. 388 - 391
Journal Article
Cell Biochemistry and Function, ISSN 0263-6484, 12/2016, Volume 34, Issue 8, pp. 620 - 627
Journal Article
Molecular & Biochemical Parasitology, ISSN 0166-6851, 04/2013, Volume 188, Issue 2, pp. 99 - 108
Exposure of to various stress stimuli upregulates an endonucleolytic pathway leading to the production of half-tRNA molecules with putative regulatory...
tRNA cleavage | Stress stimuli | Plasmodium berghei | Toxoplasma gondii | Half-tRNAs | Differentiation | OXIDATIVE STRESS | TRNASE-Z | BIOCHEMISTRY & MOLECULAR BIOLOGY | INFECTIVITY | BRADYZOITES | HUMAN-FIBROBLASTS | CYST FORMATION | GROWTH | TACHYZOITES | EXPRESSION | PARASITOLOGY | Hydrolysis | Plasmodium berghei - metabolism | Toxoplasma - genetics | RNA Processing, Post-Transcriptional | RNA, Transfer - metabolism | Plasmodium berghei - genetics | Gene Expression Regulation | Toxoplasma - metabolism | Parasitic diseases | Transfer RNA
tRNA cleavage | Stress stimuli | Plasmodium berghei | Toxoplasma gondii | Half-tRNAs | Differentiation | OXIDATIVE STRESS | TRNASE-Z | BIOCHEMISTRY & MOLECULAR BIOLOGY | INFECTIVITY | BRADYZOITES | HUMAN-FIBROBLASTS | CYST FORMATION | GROWTH | TACHYZOITES | EXPRESSION | PARASITOLOGY | Hydrolysis | Plasmodium berghei - metabolism | Toxoplasma - genetics | RNA Processing, Post-Transcriptional | RNA, Transfer - metabolism | Plasmodium berghei - genetics | Gene Expression Regulation | Toxoplasma - metabolism | Parasitic diseases | Transfer RNA
Journal Article
2014, Methods in Enzymology, ISBN 0123979269, Volume 534, 21
The endosomal–lysosomal system plays important roles in cellular physiology. Beyond the well-known function as terminal degradative compartment, necessary to...
Lysosomes | Lipid microdomains | Gangliosides | Glycohydrolases | Plasma membrane | Cell membranes | ACTIVATION | DETERGENTS | EXOCYTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-N-ACETYLHEXOSAMINIDASE | BIOCHEMICAL RESEARCH METHODS | DIFFERENTIATION | IDENTIFICATION | HEXOSAMINIDASE | FIBROBLASTS | GALACTOSIDASE | LYMPHOCYTES | Lysosomes - chemistry | Membrane Microdomains - metabolism | Humans | Green Fluorescent Proteins - genetics | beta-N-Acetylhexosaminidases - chemistry | Endosomes - metabolism | Lysosomes - metabolism | beta-Galactosidase - metabolism | G(M1) Ganglioside - chemistry | beta-Galactosidase - chemistry | Genes, Reporter | Green Fluorescent Proteins - metabolism | Gene Expression | Biotinylation | Chromatography, DEAE-Cellulose | Jurkat Cells | beta-N-Acetylhexosaminidases - isolation & purification | beta-N-Acetylhexosaminidases - metabolism | Membrane Microdomains - chemistry | Protein Transport | Chromatography, Affinity | beta-Galactosidase - isolation & purification | Endosomes - chemistry | G(M1) Ganglioside - metabolism | Microscopy, Fluorescence
Lysosomes | Lipid microdomains | Gangliosides | Glycohydrolases | Plasma membrane | Cell membranes | ACTIVATION | DETERGENTS | EXOCYTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-N-ACETYLHEXOSAMINIDASE | BIOCHEMICAL RESEARCH METHODS | DIFFERENTIATION | IDENTIFICATION | HEXOSAMINIDASE | FIBROBLASTS | GALACTOSIDASE | LYMPHOCYTES | Lysosomes - chemistry | Membrane Microdomains - metabolism | Humans | Green Fluorescent Proteins - genetics | beta-N-Acetylhexosaminidases - chemistry | Endosomes - metabolism | Lysosomes - metabolism | beta-Galactosidase - metabolism | G(M1) Ganglioside - chemistry | beta-Galactosidase - chemistry | Genes, Reporter | Green Fluorescent Proteins - metabolism | Gene Expression | Biotinylation | Chromatography, DEAE-Cellulose | Jurkat Cells | beta-N-Acetylhexosaminidases - isolation & purification | beta-N-Acetylhexosaminidases - metabolism | Membrane Microdomains - chemistry | Protein Transport | Chromatography, Affinity | beta-Galactosidase - isolation & purification | Endosomes - chemistry | G(M1) Ganglioside - metabolism | Microscopy, Fluorescence
Book Chapter
World Neurosurgery, ISSN 1878-8750, 04/2018, Volume 112, pp. e342 - e347
Clinical and molecular factors are essential to define the prognosis in patients with glioblastoma (GBM). O6-methylguanine-DNA methyltransferase (MGMT)...
PERNO | Gender | Methylation | MGMT | Glioblastoma | SURVIVAL | SURGERY | RESECTION | NEWLY-DIAGNOSED GLIOBLASTOMA | MULTIFORME | CARE | CLINICAL NEUROLOGY | TEMOZOLOMIDE | EXTENT
PERNO | Gender | Methylation | MGMT | Glioblastoma | SURVIVAL | SURGERY | RESECTION | NEWLY-DIAGNOSED GLIOBLASTOMA | MULTIFORME | CARE | CLINICAL NEUROLOGY | TEMOZOLOMIDE | EXTENT
Journal Article
Journal of Neuro-Oncology, ISSN 0167-594X, 01/2018, Volume 136, Issue 1, pp. 221 - 222
Journal Article