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Endocrinology, ISSN 0013-7227, 10/2013, Volume 154, Issue 10, pp. 3552 - 3564
Journal Article
Journal Article
Development, ISSN 0950-1991, 09/2018, Volume 145, Issue 17, p. dev163568
Journal Article
Endocrinology, ISSN 0013-7227, 12/2012, Volume 153, Issue 12, pp. 5782 - 5795
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2010, Volume 285, Issue 6, pp. 3973 - 3985
Journal Article
Endocrinology, ISSN 0013-7227, 01/2016, Volume 157, Issue 1, pp. 176 - 194
The 2 gut hormones glucagon-like peptide-1 (GLP-1) and peptide YY (PYY) are well known to be coexpressed, costored, and released together to coact in the... 
PROXIMAL SMALL-INTESTINE | ENERGY-BALANCE | PANCREATIC ENDOCRINE RESPONSES | GLUCAGON-LIKE PEPTIDE-1 | FOOD-INTAKE | ENDOCRINOLOGY & METABOLISM | GASTRIC-ACID SECRETION | CENTRAL-NERVOUS-SYSTEM | DEPENDENT INSULINOTROPIC POLYPEPTIDE | CELL-DIFFERENTIATION | BINDING-SITES | Intestinal Mucosa - metabolism | Peptide YY - metabolism | Rats, Wistar | Receptors, G-Protein-Coupled - metabolism | Enteroendocrine Cells - ultrastructure | Humans | Intestinal Mucosa - secretion | Neurotensin - secretion | Secretory Vesicles - metabolism | Ileum - metabolism | Male | Peptide Fragments - pharmacology | Recombinant Fusion Proteins - metabolism | Enteroendocrine Cells - secretion | Glucagon-Like Peptide 1 - genetics | Intestinal Mucosa - drug effects | Neurotensin - metabolism | Ileum - drug effects | Bombesin - pharmacology | Ileum - ultrastructure | Female | Enteroendocrine Cells - metabolism | Peptide YY - genetics | Genes, Reporter | Biomarkers - metabolism | Glucagon-Like Peptide 1 - metabolism | Intestinal Mucosa - ultrastructure | Secretory Vesicles - ultrastructure | Tissue Culture Techniques | Mice, Inbred C57BL | Mice, Transgenic | Ileum - secretion | Gene Expression Regulation - drug effects | Neurotensin - genetics | Secretory Vesicles - secretion | Animals | Secretory Vesicles - drug effects | Recombinant Fusion Proteins - genetics | Luminescent Proteins - genetics | Receptors, G-Protein-Coupled - genetics | Enteroendocrine Cells - drug effects | Luminescent Proteins - metabolism | Endokrinologi och diabetes | GASTRIC-ACID | SECRETION | Endocrinology and Diabetes
Journal Article
Molecular Metabolism, ISSN 2212-8778, 01/2015, Volume 4, Issue 1, pp. 3 - 14
Objectives: GPR40 (FFAR1), a clinically proven anti-diabetes target, is a Gq-coupled receptor for long chain fatty acids (LCFA) stimulating insulin secretion... 
G protein-coupled receptor | Biased signaling | Ago-allosteric agonist | Glucagon like peptide 1 (GLP-1) | Long chain fatty acids (LCFAs)
Journal Article
Endocrinology, ISSN 0013-7227, 11/2015, Volume 156, Issue 11, pp. 3909 - 3923
In the stomach, somatostatin (SST) acts as a general paracrine negative regulator of exocrine secretion of gastric acid and pepsinogen and endocrine secretion... 
PERFUSED RAT STOMACH | CALCIUM-SENSING RECEPTOR | GLUCAGON-LIKE PEPTIDE-1 | GROWTH-HORMONE | GHRELIN SECRETION | ENTEROENDOCRINE CELLS | ACID-SECRETION | ENDOCRINOLOGY & METABOLISM | ISLET AMYLOID POLYPEPTIDE | RELEASE-INHIBITING HORMONE | ENDOCRINE-CELLS | Peptide YY - metabolism | Receptors, G-Protein-Coupled - metabolism | Humans | Transcriptome | Male | Receptors, Muscarinic - metabolism | Receptors, Neuropeptide - metabolism | Islet Amyloid Polypeptide - genetics | Stomach - metabolism | Gastric Mucosa - metabolism | Receptors, Somatostatin - genetics | Glucagon-Like Peptide-1 Receptor - genetics | Glucagon-Like Peptide-1 Receptor - metabolism | In Situ Hybridization | Receptors, Adrenergic - genetics | Receptors, Somatostatin - metabolism | Peptide YY - genetics | Somatostatin - metabolism | Receptors, Muscarinic - genetics | Somatostatin - secretion | Somatostatin - genetics | Receptors, Adrenergic - metabolism | Cells, Cultured | Islet Amyloid Polypeptide - metabolism | Receptors, Neuropeptide - genetics | Mice, Transgenic | Gastric Mucosa - cytology | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Microscopy, Confocal | Animals | Stomach - cytology | Luminescent Proteins - genetics | Receptors, G-Protein-Coupled - genetics | Somatostatin-Secreting Cells - metabolism | Luminescent Proteins - metabolism
Journal Article
Development (Cambridge), ISSN 0950-1991, 09/2018, Volume 145, Issue 17
Mutations in Hes1, a target gene of the Notch signalling pathway, lead to ectopic pancreas by a poorly described mechanism. Here, we use genetic inactivation... 
Morphogenesis | Hes1 | Neurog3 | Ectopic pancreas | FOREGUT PROGENITOR CELLS | MOUSE | ENDODERM | DEVELOPMENTAL BIOLOGY | ENDOCRINE DEVELOPMENT | DIFFERENTIATION | TRANSCRIPTION FACTOR | ISLET CELLS | EXPRESSION | SONIC-HEDGEHOG | REVEALS
Journal Article
American journal of physiology. Endocrinology and metabolism, ISSN 0193-1849, 09/2019
DPP-4 inhibitors, used for treatment of type 2 diabetes, act by increasing the concentrations of intact GLP-1 but at the same time they inhibit secretion of... 
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2017, Volume 60, Issue 3, pp. 886 - 898
The G-protein-coupled receptor 39 (GPR39) is a G-protein-coupled receptor activated by Zn2+. We used a homology model-based approach to identify small-molecule... 
CHEMISTRY, MEDICINAL | 7TM RECEPTORS | LIGANDS | CRYSTAL-STRUCTURE | GHRELIN | DRUG DISCOVERY | IN-VIVO | ZINC RECEPTOR | ALLOSTERIC MODULATION | IDENTIFICATION | BETA-ADRENERGIC RECEPTOR
Journal Article