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1. Full Text Colonic spirochetosis is associated with colonic eosinophilia and irritable bowel syndrome in a general population in Sweden
by Walker, Marjorie M., BMBS, FRCPath and Talley, Nicholas J., MD, PhD and Inganäs, Linn, MSc and Engstrand, Lars, MD, PhD and Jones, Michael P., PhD and Nyhlin, Henry, MD, PhD and Agréus, Lars, MD, PhD and Kjellstrom, Lars, MD and Öst, Åke, MD, PhD and Andreasson, Anna, PhD and Stockholms universitet and Samhällsvetenskapliga fakulteten and Stressforskningsinstitutet
Human Pathology, ISSN 0046-8177, 2015, Volume 46, Issue 2, pp. 277 - 283
Summary Irritable bowel syndrome (IBS) is a functional disorder defined by symptoms in the absence of overt pathology. Colonic spirochetosis (CS), defined by... 
Pathology | Infective colitis | Histopathology | Colonic spirochetosis | Irritable bowel syndrome | Eosinophils | HUMAN INTESTINAL SPIROCHETOSIS | COLONOSCOPY | DIARRHEA | PREVALENCE | PATHOLOGY | FEATURES | COLITIS | HOMOSEXUAL-MEN | Prevalence | Colon - pathology | Rectum - pathology | Humans | Middle Aged | Male | Eosinophilia - epidemiology | Sweden - epidemiology | Colonoscopy - methods | Young Adult | Biopsy | Irritable Bowel Syndrome - diagnosis | Adult | Female | Aged | Irritable Bowel Syndrome - epidemiology | Immunohistochemistry | Eosinophilia | Gastrointestinal diseases | Colorectal cancer | Diarrhea | Infections | Histology | Abdomen | Studies | Microscopy | Human immunodeficiency virus--HIV | Questionnaires | Population | Constipation | Age | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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2. Full Text Isolates from Colonic Spirochetosis in Humans Show High Genomic Divergence and Potential Pathogenic Features but Are Not Detected Using Standard Primers for the Human Microbiota
by Thorell, K and Inganas, L and Backhans, A and Agreus, L and Ost, A and Walker, MM and Talley, NJ and Kjellstrom, L and Andreasson, A and Engstrand, L and Stockholms universitet and Samhällsvetenskapliga fakulteten and Stressforskningsinstitutet
JOURNAL OF BACTERIOLOGY, ISSN 0021-9193, 10/2019, Volume 201, Issue 21
Colonic spirochetosis, diagnosed based on the striking appearance in histological sections, still has an obscure clinical relevance, and only a few bacterial... 
Brachyspira | HUMAN INTESTINAL SPIROCHETOSIS | POPULATION | SERPULINA PILOSICOLI | COLLAGENASE | spirochetosis | whole-genome sequencing | PROTEIN FAMILY CLASSIFICATION | MICROBIOLOGY | RIBOSOMAL-RNA | IDENTIFICATION | MULTIPLE SEQUENCE ALIGNMENT | comparative genomics | BRACHYSPIRA-AALBORGI | IRRITABLE-BOWEL-SYNDROME | Incompatibility | Strain analysis | Divergence | Spirochetosis | Leukocytes (eosinophilic) | Mucosa | Virulence | Population studies | Genomes | Gene sequencing | Heterogeneity | Microbiota | Mucin | Biopsy | Intestine | Irritable bowel syndrome | Colon | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Gastroenterologi | Klinisk medicin | Gastroenterology and Hepatology
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3. Full Text Low diversity of the gut microbiota in infants with atopic eczema
by Abrahamsson, Thomas R., MD, PhD and Jakobsson, Hedvig E., MSc and Andersson, Anders F., PhD and Björkstén, Bengt, MD, PhD and Engstrand, Lars, MD, PhD and Jenmalm, Maria C., PhD and Science for Life Laboratory, SciLifeLab and Centra and Skolan för bioteknologi (BIO) and KTH and Genteknologi
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2011, Volume 129, Issue 2, pp. 434 - 440.e2
Background It is debated whether a low total diversity of the gut microbiota in early childhood is more important than an altered prevalence of particular... 
Allergy and Immunology | microbiota | Sutterella species | diversity | hygiene hypothesis | Allergic disease | eczema | pyrosequencing | molecular microbiology | infant | Bacteroides species | MICROFLORA | INTESTINAL MICROBIOTA | RISK | IMMUNOLOGY | MOLECULAR ANALYSIS | REDUCED DIVERSITY | ALLERGY | EXPOSURE | Eczema - diagnosis | Hypersensitivity - prevention & control | Humans | Child, Preschool | Food Hypersensitivity - blood | Infant | Male | Eczema - microbiology | Immunoglobulin E - blood | Feces - microbiology | Food Hypersensitivity - immunology | Allergens - immunology | Hypersensitivity - microbiology | Hypersensitivity - diagnosis | Bacteria - classification | DNA, Bacterial - analysis | Female | Eczema - prevention & control | Infant, Newborn | Bacteria - genetics | Sequence Analysis, DNA | Intestines - microbiology | RNA, Ribosomal, 16S - genetics | Probiotics - therapeutic use | Food Hypersensitivity - diagnosis | Autoimmunity | Allergy | Analysis | Infants | Universities and colleges | Gene expression | Allergic reaction | Studies | Allergies | Eczema | Children & youth | debated whether | rosequencing | gut microbiota | bacteroides species | Naturvetenskap | sutterella species | Natural Sciences | low diversity | allergic disease
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4. Full Text Missing microbes – A must-read written by an influential pioneer
by Engstrand, Lars
Anaerobe, ISSN 1075-9964, 04/2016, Volume 38, pp. 138 - 139
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5. Full Text Helicobacter pylori and the gastric microbiota
by Engstrand, Lars, MD and Lindberg, Mathilda, PhD
Best Practice & Research: Clinical Gastroenterology, ISSN 1521-6918, 2013, Volume 27, Issue 1, pp. 39 - 45
Abstract The human microbiota along the gastrointestinal tract is currently extensively studied and a number of studies focuses on elucidating the association... 
Gastroenterology and Hepatology | Stomach | Gastric microbiota | Helicobacter pylori | Atrophic gastritis | Gastric cancer | Acid reducing medication | MICROFLORA | ESOPHAGUS | BACTERIAL MICROBIOTA | OMEPRAZOLE | HUMAN STOMACH | COLONIZATION | INDIVIDUALS | INFECTION | ACID-SUPPRESSIVE THERAPY | GASTROENTEROLOGY & HEPATOLOGY | BIOPSIES | Gastritis, Atrophic - physiopathology | Humans | Gastric Acid - physiology | Helicobacter pylori - physiology | Stomach - microbiology | Metagenome - physiology | Hydrogen-Ion Concentration | Gastrointestinal system | Cells
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6. Full Text Stool frequency is associated with gut microbiota composition
by Hadizadeh, Fatemeh and Walter, Susanna and Belheouane, Meriem and Bonfiglio, Ferdinando and Heinsen, Femke-Anouska and Andreasson, Anna and Agreus, Lars and Engstrand, Lars and Baines, John F and Rafter, Joseph and Franke, Andre and D'Amato, Mauro and Avdelningen för neuro- och inflammationsvetenskap and Medicinska fakulteten and Region Östergötland and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Magtarmmedicinska kliniken and Hjärt- och Medicincentrum
Gut, ISSN 0017-5749, 03/2017, Volume 66, Issue 3, pp. 559 - 560
GASTROENTEROLOGY & HEPATOLOGY | CONSISTENCY | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Gastroenterologi | GASTROINTESTINAL TRANSIT; INTESTINAL BACTERIA | Klinisk medicin | Gastroenterology and Hepatology
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7. Full Text Functional variants in the sucrase–isomaltase gene associate with increased risk of irritable bowel syndrome
by Henström, Maria and Diekmann, Lena and Bonfiglio, Ferdinando and Hadizadeh, Fatemeh and Kuech, Eva-Maria and von Köckritz-Blickwede, Maren and Thingholm, Louise B and Zheng, Tenghao and Assadi, Ghazaleh and Dierks, Claudia and Heine, Martin and Philipp, Ute and Distl, Ottmar and Money, Mary E and Belheouane, Meriem and Heinsen, Femke-Anouska and Rafter, Joseph and Nardone, Gerardo and Cuomo, Rosario and Usai-Satta, Paolo and Galeazzi, Francesca and Neri, Matteo and Walter, Susanna and Simrén, Magnus and Karling, Pontus and Ohlsson, Bodil and Schmidt, Peter T and Lindberg, Greger and Dlugosz, Aldona and Agreus, Lars and Andreasson, Anna and Mayer, Emeran and Baines, John F and Engstrand, Lars and Portincasa, Piero and Bellini, Massimo and Stanghellini, Vincenzo and Barbara, Giovanni and Chang, Lin and Camilleri, Michael and Franke, Andre and Naim, Hassan Y and D'Amato, Mauro and Avdelningen för neuro- och inflammationsvetenskap and Medicinska fakulteten and Region Östergötland and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Magtarmmedicinska kliniken and Hjärt- och Medicincentrum and Centrum för medicinsk bildvetenskap och visualisering, CMIV
Gut, ISSN 0017-5749, 02/2018, Volume 67, Issue 2, pp. 263 - 270
ObjectiveIBS is a common gut disorder of uncertain pathogenesis. Among other factors, genetics and certain foods are proposed to contribute. Congenital... 
DIARRHOEA | POLYMORPHIC VARIATION | GENETICS | IRRITABLE BOWEL SYNDROME | CONTROLLED-TRIAL | POPULATION | CONSTIPATION | DIARRHEA | SYMPTOMS | MICROBIOTA | POLYMORPHISM | IDENTIFICATION | GASTROENTEROLOGY & HEPATOLOGY | SYNDROME IBS | DEFICIENCY | Exons | Humans | Irritable Bowel Syndrome - enzymology | Middle Aged | Male | Carbohydrate Metabolism, Inborn Errors - genetics | Case-Control Studies | Feces - microbiology | Sucrase-Isomaltase Complex - metabolism | Transfection | DNA Mutational Analysis | Adult | Female | Cell Line | Sucrase-Isomaltase Complex - genetics | Risk Factors | Sucrase-Isomaltase Complex - deficiency | Genotype | Gene Dosage | Irritable Bowel Syndrome - genetics | Haplorhini | Cell Membrane - enzymology | Phenotype | Animals | Irritable Bowel Syndrome - complications | Diarrhea - etiology | Polymorphism, Single Nucleotide | Defecation - genetics | Carbohydrates | Enzymes | Phenotypes | Congenital diseases | Disaccharides | Genes | Diarrhea | Patients | Gene polymorphism | Population genetics | Nutrition research | Hypotheses | Microbiota | Pain | Enzymatic activity | Intestine | Gastroenterology | Irritable bowel syndrome | Population | Malabsorption | Mutation | 1506 | Neurogastroenterology | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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8. Full Text Decreased gut microbiota diversity, delayed Bacteroidetes colonisation and reduced Th1 responses in infants delivered by Caesarean section
by Jakobsson, Hedvig E and Abrahamsson, Thomas R and Jenmalm, Maria C and Harris, Keith and Quince, Christopher and Jernberg, Cecilia and Björkstén, Bengt and Engstrand, Lars and Andersson, Anders F and Science for Life Laboratory, SciLifeLab and Centra and Skolan för bioteknologi (BIO) and KTH and Genteknologi
Gut, ISSN 0017-5749, 04/2014, Volume 63, Issue 4, pp. 559 - 566
Objective The early intestinal microbiota exerts important stimuli for immune development, and a reduced microbial exposure as well as caesarean section (CS)... 
BACTERIA | ALLERGY | INTESTINAL MICROBIOTA | ECZEMA | IMMUNE-RESPONSES | FECAL SAMPLES | MODE | ASTHMA | GASTROENTEROLOGY & HEPATOLOGY | T-CELLS | CHILDREN | Cesarean Section - adverse effects | Chemokine CXCL10 - blood | Chemokine CXCL11 - physiology | Microbiota - physiology | Th1 Cells - physiology | Age Factors | Humans | Chemokine CXCL10 - physiology | Infant | Male | Bacteroidetes - physiology | Feces - microbiology | DNA, Bacterial - genetics | Intestines - microbiology | Microbiota - genetics | Immunity, Cellular - physiology | RNA, Ribosomal, 16S - genetics | Female | Bacteroidetes - genetics | Chemokine CXCL11 - blood | Infant, Newborn | Anaerobic bacteria | Microbiota (Symbiotic organisms) | Influence | Infants | Research | T cells | Health aspects | Disease | Weaning | Mothers | Allergies | Children & youth | Childbirth & labor | Studies | Babies | Gene amplification | Antibiotics | Cesarean section | Chemokines | Deoxyribonucleic acid--DNA | Immune system | Allergy | Immune-Responses | Medical and Health Sciences | Intestinal Microbiota | Medicin och hälsovetenskap | Gastroenterologi | Mode | Fecal Samples | Klinisk medicin | T-Cells | Asthma | Clinical Medicine | Eczema | Bacteria | Children | Gastroenterology and Hepatology
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9. Full Text Helicobacter pylori eradication treatment and the risk of gastric adenocarcinoma in a Western population
by Doorakkers, Eva and Lagergren, Jesper and Engstrand, Lars and Brusselaers, Nele and Inst för molekylär medicin och kirurgi and Karolinska Institutet and Dept of Molecular Medicine and Surgery
Gut, ISSN 0017-5749, 12/2018, Volume 67, Issue 12, pp. 2092 - 2096
ObjectiveGastric infection with Helicobacter pylori is a strong risk factor for non-cardia gastric adenocarcinoma. The aim of this study was to assess whether... 
helicobacter pylori | gastric cancer | antibiotic therapy | GASTROENTEROLOGY & HEPATOLOGY | INFECTION | PREVALENCE | Risk Assessment - methods | Adenocarcinoma - pathology | Humans | Middle Aged | Helicobacter Infections - complications | Male | Stomach Neoplasms - pathology | Young Adult | Anti-Bacterial Agents - therapeutic use | Helicobacter pylori | Time Factors | Helicobacter Infections - drug therapy | Adult | Female | Registries | Stomach Neoplasms - epidemiology | Drug Therapy, Combination | Adenocarcinoma - microbiology | Helicobacter Infections - epidemiology | Cardia | Proton Pump Inhibitors - therapeutic use | Sweden - epidemiology | Stomach Neoplasms - microbiology | Adolescent | Aged | Adenocarcinoma - epidemiology | Health care | Adenocarcinoma | Medical research | Systematic review | Population studies | Infections | Histology | Cancer therapies | Stomach cancer | Studies | Prevention | Antibiotics | Ulcers | Population | Clinical medicine | Health risk assessment | Prescriptions | MEDICIN OCH HÄLSOVETENSKAP | MEDICAL AND HEALTH SCIENCES
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10. Full Text Faecal microbiota composition associates with abdominal pain in the general population
by Hadizadeh, Fatemeh and Bonfiglio, Ferdinando and Belheouane, Meriem and Vallier, Marie and Sauer, Sascha and Bang, Corinna and Bujanda, Luis and Andreasson, Anna and Agreus, Lars and Engstrand, Lars and Talley, Nicholas J and Rafter, Joseph and Baines, John F and Walter, Susanna and Franke, Andre and D’Amato, Mauro and Avdelningen för neuro- och inflammationsvetenskap and Medicinska fakulteten and Region Östergötland and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Magtarmmedicinska kliniken and Hjärt- och Medicincentrum
Gut, ISSN 0017-5749, 04/2018, Volume 67, Issue 4, pp. 778 - 779
Previously, it has been shown that visceral hypersensitivity can be modulated or even induced in animal models, by altering the composition of their gut... 
abdominal pain | colonic microflora | GASTROENTEROLOGY & HEPATOLOGY | IRRITABLE-BOWEL-SYNDROME | Microbiota | Abdominal Pain | Feces | Humans | Animal models | Taxonomy | Hypersensitivity | Principal components analysis | Transplantation | Abdomen | Studies | Pain | Antibiotics | Colonoscopy | Irritable bowel syndrome | Population | Colon | 2312 | 1506 | PostScript | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Gastroenterology and Hepatology | Gastroenterologi
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11. Full Text Det är meddelande om att NPPRJ tas över av De Gruyter och Bosses tack när han lämnar NPPRJ
by Engstrand, Per and Wågberg, Lars
Nordic Pulp and Paper Research Journal, ISSN 0283-2631, 12/2017, Volume 32, Issue 4, p. 482
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12. Full Text Comparative analysis of human gut microbiota by barcoded pyrosequencing
by Andersson, Anders F and Lindberg, Mathilda and Jakobsson, Hedvig and Bäckhed, Fredrik and Nyrén, Pål and Engstrand, Lars and Skolan för bioteknologi (BIO) and KTH
PLoS ONE, ISSN 1932-6203, 07/2008, Volume 3, Issue 7, pp. e2836 - e2836
Humans host complex microbial communities believed to contribute to health maintenance and, when in imbalance, to the development of diseases. Determining the... 
BIOLOGY | Humans | Middle Aged | Ecology | Phylogeny | DNA Primers | Genetic Techniques | Sequence Analysis, DNA | Intestines - microbiology | Biopsy | Models, Biological | Adult | Aged | Microbiological Techniques | Endoscopy | Stomach - microbiology | Microbiota (Symbiotic organisms) | RNA | Bar codes | Analysis | Nucleotide sequencing | Health aspects | DNA sequencing | Microbial activity | Stomach | rRNA 16S | Communities | Taxonomy | Cloning | Variable region | Biology | Pharynx | Disease control | Data bases | Gene sequencing | Microorganisms | Infectious diseases | Acids | Ulcers | Phylogenetics | Population | Bacteria | Comparative analysis | Methods | Medical and Health Sciences | Medicin och hälsovetenskap
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13. Full Text Maintenance therapy with proton pump inhibitors and risk of gastric cancer: a nationwide population-based cohort study in Sweden
by Brusselaers, Nele and Wahlin, Karl and Engstrand, Lars and Lagergren, Jesper
BMJ Open, ISSN 2044-6055, 10/2017, Volume 7, Issue 10, p. e017739
ObjectiveProton pump inhibitors (PPIs) are among the most commonly prescribed drugs. Concerns have been raised about a potentially increased risk of gastric... 
PPI | Proton pump inhibitors | Gastric cancer | Chemoprevention | ADULTS | REGISTER | MEDICINE, GENERAL & INTERNAL | INCREASE | DRUGS | Proton Pump Inhibitors - adverse effects | Age Factors | Adenocarcinoma - etiology | Humans | Middle Aged | Risk Factors | Histamine H2 Antagonists - adverse effects | Male | Proton Pump Inhibitors - therapeutic use | Sweden - epidemiology | Histamine H2 Antagonists - therapeutic use | Aspirin - administration & dosage | Incidence | Time Factors | Aged, 80 and over | Adult | Female | Stomach Neoplasms - epidemiology | Aged | Gastroesophageal Reflux - drug therapy | Stomach Neoplasms - etiology | Cohort Studies | Medical research | Codes | Calendars | Patients | Cancer therapies | Stomach cancer | Studies | Antibiotics | Ulcers | Classification | Population | Health risk assessment | Drug dosages | Age | Tumors
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