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Current Opinion in Oncology, ISSN 1040-8746, 08/2019
PURPOSE OF REVIEWThe current review summarizes recent advances on three important issues in neurofibromatosis type 1 (NF1) managementthe identification of... 
Journal Article
Nature Genetics, ISSN 1061-4036, 07/2016, Volume 48, Issue 7, pp. 768 - 776
Glioblastoma (GBM) is the most common and aggressive primary brain tumor. To better understand how GBM evolves, we analyzed longitudinal genomic and... 
GENE FUSIONS | TGF-BETA | CANCER GENOMICS | LANDSCAPE | GLIOMA | GENETICS & HEREDITY | GENOMIC ALTERATIONS | MSH6 MUTATIONS | SEQUENCING DATA | BRAIN-TUMORS | TEMOZOLOMIDE | Cell Proliferation | Dacarbazine - therapeutic use | Genomics | Humans | Brain Neoplasms - pathology | DNA Repair Enzymes - genetics | Gene Expression Regulation, Neoplastic | Transcriptome | Neoplasm Recurrence, Local - drug therapy | Clonal Evolution - genetics | Neoplasm Recurrence, Local - pathology | Neoplasm Grading | Glioblastoma - genetics | Tumor Suppressor Proteins - genetics | Dacarbazine - analogs & derivatives | Brain Neoplasms - genetics | Isocitrate Dehydrogenase - genetics | Survival Rate | Brain Neoplasms - drug therapy | Mutation - genetics | Antineoplastic Agents, Alkylating - therapeutic use | Latent TGF-beta Binding Proteins - genetics | DNA Modification Methylases - genetics | Transforming Growth Factor beta - genetics | Glioblastoma - pathology | Neoplasm Recurrence, Local - genetics | Biomarkers, Tumor - genetics | Glioblastoma - drug therapy | Longitudinal Studies | Molecular targeted therapy | Care and treatment | Gene mutations | Development and progression | Genetic aspects | Genetic transcription | Glioblastoma multiforme | Health aspects | Methods | Brain cancer | Genomes | Gene expression | Cancer therapies | Studies | Archives & records | DNA methylation | Mathematical models | Mutation | Deoxyribonucleic acid--DNA | Tumors | Cancer | Index Medicus
Journal Article
Journal Article
The Lancet Oncology, ISSN 1470-2045, 01/2019, Volume 20, Issue 1, pp. 110 - 119
Glioblastoma is a highly vascularised tumour and there are few treatment options after disease recurrence. Regorafenib is an oral multikinase inhibitor of... 
GLIOMAS | FOTEMUSTINE | MONOTHERAPY | THERAPY | EFFICACY | ONCOLOGY | BEVACIZUMAB | SAFETY | COMBINATION | TUMORS | TEMOZOLOMIDE | Care and treatment | Relapse | Clinical trials | Lomustine | Comparative analysis | Radiotherapy | Glioblastoma multiforme | Diseases
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, pp. e90535 - e90535
Background: Perfusion weighted imaging (PWI) can be used to measure key aspects of tumor vascularity in vivo and recent studies suggest that perfusion imaging... 
GLIOMAS | SURVIVAL | BIOMARKERS | BRAIN-TUMOR | CEREBRAL BLOOD-VOLUME | HISTOGRAM ANALYSIS | MULTIDISCIPLINARY SCIENCES | GRADE | ANTI-ANGIOGENIC THERAPY | MULTIFORME | PROGRESSION | Follow-Up Studies | Humans | Middle Aged | Magnetic Resonance Imaging - methods | Male | Young Adult | Adult | Camptothecin - administration & dosage | Female | Brain Neoplasms - mortality | Camptothecin - analogs & derivatives | Bevacizumab - administration & dosage | Glioblastoma - diagnosis | Brain Neoplasms - diagnosis | Perfusion Imaging - methods | Neoplasm Recurrence, Local | Treatment Outcome | Combined Modality Therapy | Brain Neoplasms - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | Survival Analysis | Aged | Glioblastoma - drug therapy | Glioblastoma - mortality | Medicine, Experimental | Medical research | Angiogenesis inhibitors | Magnetic resonance imaging | Nuclear magnetic resonance--NMR | Image processing | Brain cancer | Oncology | Blood | Bevacizumab | Angiogenesis | Maps | Blood volume | Mathematical analysis | Cerebral blood flow | Vascular endothelial growth factor | Automation | Patients | Survival | Irinotecan | Perfusion | Antiangiogenics | Medical prognosis | Radiology | Biomarkers | In vivo methods and tests | Tumors | Index Medicus | Nuclear magnetic resonance | NMR
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, pp. e114713 - e114713
Background: The endothelium is not a homogeneous organ. Endothelial cell heterogeneity has been described at the level of cell morphology, function, gene... 
PROGENITOR CELLS | BREAST-CANCER | HETEROGENEITY | LUNG-CANCER | BEVACIZUMAB | MULTIDISCIPLINARY SCIENCES | RECEPTOR | FLOW-CYTOMETRY | PATHOLOGICAL ANGIOGENESIS | IDENTIFICATION | METRONOMIC CHEMOTHERAPY | Neoplastic Cells, Circulating - pathology | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Neoplastic Cells, Circulating - metabolism | Male | CD146 Antigen - genetics | Antigens, CD - genetics | CD146 Antigen - blood | Antigens, CD - analysis | Neoplasms - blood | Glioblastoma - genetics | Neoplasms - genetics | Adult | Female | Neoplasm Proteins - genetics | CD146 Antigen - analysis | Endothelial Cells - metabolism | GPI-Linked Proteins - analysis | Glioblastoma - blood | Antigens, CD - blood | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Glioblastoma - pathology | Breast Neoplasms - blood | GPI-Linked Proteins - blood | Neoplasm Proteins - analysis | Neoplasm Proteins - blood | Aged | Endothelial Cells - pathology | Neoplasms - pathology | GPI-Linked Proteins - genetics | Flow cytometry | Laboratories | Glioblastoma | Cytology | Oncology | Identification | Kinases | Blood | CD45 antigen | Cell morphology | Angiogenesis | Embryogenesis | Peripheral blood | Deoxyribonucleic acid--DNA | Antigens | Phenotypes | Hematology | Breast cancer | Gene expression | Cadherin | Patients | Endothelial cells | Endothelium | Embryonic growth stage | Polymerase chain reaction | White blood cells | Cytometry | Blood circulation | Ribonucleic acids | Viability | Cancer | Apoptosis | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Nature Medicine, ISSN 1078-8956, 01/2019, Volume 25, Issue 1, pp. 176 - 187
Journal Article
by Brennan, Cameron W and Verhaak, Roel G.W and McKenna, Aaron and Campos, Benito and Noushmehr, Houtan and Salama, Sofie R and Zheng, Siyuan and Chakravarty, Debyani and Sanborn, J. Zachary and Berman, Samuel H and Beroukhim, Rameen and Bernard, Brady and Wu, Junyuan and Wu, Chang-Jiun and Genovese, Giannicola and Shmulevich, Ilya and Barnholtz-Sloan, Jill and Zou, Lihua and Vegesna, Rahulsimham and Shukla, Sachet A and Ciriello, Giovanni and Yung, W.K and Yung, W.K. Alfred and Zhang, Zhaobin and Zhang, Wei and Zhang, Jianhua and Zhang, Hailei and Sougnez, Carrie and Mikkelsen, Tom and Aldape, Kenneth and Bigner, Darell D and Bigner, Darell and Van Meir, Erwin G and Prados, Michael and Sloan, Andrew and Sloan, Andrew E and Black, Keith L and Eschbacher, Jennifer and Finocchiaro, Gaetano and Friedman, William and Andrews, David W and Guha, Abhijit and Iacocca, Mary and O’Neill, Brian P and Foltz, Greg and Myers, Jerome and Weisenberger, Daniel J and Penny, Robert and Kucherlapati, Raju and Perou, Charles M and Hayes, D. Neil and Gibbs, Richard and Marra, Marco and Mills, Gordon and Mills, Gordon B and Lander, Eric S and Lander, Eric and Spellman, Paul and Wilson, Richard K and Wilson, Richard and Sander, Chris and Weinstein, John N and Weinstein, John and Meyerson, Matthew and Gabriel, Stacey B and Gabriel, Stacey and Laird, Peter W and Haussler, David and Getz, Gad and Chin, Lynda and Benz, Christopher and Barrett, Wendi and Ostrom, Quinn and Wolinsky, Yingli and Bose, Bikash and Boulos, Madgy and Boulos, Paul T and Brown, Jenn and Czerinski, Christine and Eppley, Matthew and Kempista, Thelma and Kitko, Teresa and Koyfman, Yakov and Rabeno, Brenda and Rastogi, Pawan and Sugarman, Michael and Swanson, Patricia and Yalamanchii, Kennedy and Otey, Ilana P and Liu, Yuexin and Liu, Yingchun Spring and Liu, Wenbin and Xiao, Yonghong and Auman, J.Todd and Chen, Qing-Rong and Chen, Peng-Chieh and Chen, Ken and Hadjipanayis, Angela and Lee, Eunjung and Lee, Semin and ... and TCGA Res Network and TCGA Research Network
Cell, ISSN 0092-8674, 10/2013, Volume 155, Issue 2, pp. 462 - 477
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2017, Volume 19, Issue suppl_6, pp. vi147 - vi147
Journal Article
Journal of Neuro-Oncology, ISSN 0167-594X, 11/2015, Volume 125, Issue 2, pp. 359 - 367
Journal Article