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Kidney International, ISSN 0085-2538, 11/2013, Volume 84, Issue 5, p. 1050
Journal Article
Kidney International, ISSN 0085-2538, 02/2018, Volume 93, Issue 2, pp. 335 - 342
Journal Article
Cell and Tissue Research, ISSN 0302-766X, 10/2014, Volume 358, Issue 1, pp. 99 - 107
In man, mutations of the megalin-encoding gene causes the rare Donnai-Barrow/Facio-Oculo-Acoustico-Renal Syndrome, which is partially characterized by... 
Human Genetics | Biomedicine | Non-pigmented ciliary body epithelium | Proteomics | Myopia | Macromelanosomes | Molecular Medicine | Megalin | Retinal pigment epithelium | PROTEIN | BLOOD-AQUEOUS BARRIER | MOUSE | RATS | CUBILIN | CELL BIOLOGY | RENAL PROXIMAL TUBULE | DONNAI-BARROW-SYNDROME | MORPHOGENESIS | EXPRESSION | ENDOCYTIC RECEPTORS | Retinal Pigment Epithelium - metabolism | Ciliary Body - pathology | Hernias, Diaphragmatic, Congenital - pathology | Humans | Male | Renal Tubular Transport, Inborn Errors - genetics | Proteinuria - pathology | Ciliary Body - metabolism | Myopia - metabolism | Retinal Pigment Epithelium - pathology | Renal Tubular Transport, Inborn Errors - metabolism | Hernias, Diaphragmatic, Congenital - metabolism | Mice, Mutant Strains | Agenesis of Corpus Callosum - genetics | Low Density Lipoprotein Receptor-Related Protein-2 - genetics | Melanosomes - pathology | Low Density Lipoprotein Receptor-Related Protein-2 - biosynthesis | Agenesis of Corpus Callosum - metabolism | Hearing Loss, Sensorineural - metabolism | Renal Tubular Transport, Inborn Errors - pathology | Gene Expression Regulation | Hearing Loss, Sensorineural - pathology | Proteinuria - metabolism | Myopia - pathology | Hearing Loss, Sensorineural - genetics | Proteinuria - genetics | Agenesis of Corpus Callosum - pathology | Myopia - genetics | Hernias, Diaphragmatic, Congenital - genetics | Animals | Melanosomes - genetics | Mice | Melanosomes - metabolism | Physiological aspects | Epithelium | Cytochemistry | Analysis | Pigments | Retina | Eye diseases | Genetics | Ligands | Rodents | Index Medicus | Regular
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, pp. e25065 - e25065
Injury to the glomerular podocyte is a key mechanism in human glomerular disease and podocyte repair is an important therapeutic target. In Fabry disease,... 
RAT-KIDNEY | MULTIDISCIPLINARY SCIENCES | RENAL PATHOLOGY | HUMAN FIBROBLASTS | GLOMERULAR EPITHELIAL-CELLS | GROWTH-FACTOR-II | ENZYME REPLACEMENT THERAPY | HEYMANN NEPHRITIS ANTIGEN | AGALSIDASE-BETA THERAPY | L-IDURONIDASE | LYSOSOMAL-ENZYME | Surface Plasmon Resonance | alpha-Galactosidase - genetics | Cell Membrane | Iodine Radioisotopes | Fabry Disease - genetics | Humans | Adaptor Proteins, Vesicular Transport - genetics | Male | alpha-Galactosidase - metabolism | Adaptor Proteins, Vesicular Transport - metabolism | Immunoenzyme Techniques | Receptor, IGF Type 2 - metabolism | Receptor, IGF Type 2 - genetics | Kidney - metabolism | Insulin-Like Growth Factor II - genetics | Adult | Low Density Lipoprotein Receptor-Related Protein-2 - genetics | Recombinant Proteins - metabolism | Trihexosylceramides - metabolism | Podocytes - metabolism | RNA, Messenger - genetics | Cells, Cultured | Low Density Lipoprotein Receptor-Related Protein-2 - metabolism | Kidney - cytology | Recombinant Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Insulin-Like Growth Factor II - metabolism | Endocytosis - physiology | Podocytes - cytology | Fabry Disease - metabolism | Phosphates | Globotriaosylceramide | Drug delivery systems | Disease | Galactosidase | Biochemistry | Mannose | Biology | Drug delivery | Insulin-like growth factors | Proteins | Receptors | Endocytosis | Labeling | Localization | Carbohydrates | Antigens | Enzymes | Kidneys | Organs | Insulin | Patients | Fabry's disease | Biopsy | Intracellular | Kidney transplantation | Index Medicus
Journal Article
Nature Reviews Nephrology, ISSN 1759-5061, 12/2013, Volume 9, Issue 12, pp. 700 - 702
In a recent study using transgenic mice with inducible podocyte-specific expression of tagged albumin, Tenten and colleagues report transtubular transport of... 
UROLOGY & NEPHROLOGY | KIDNEY | NEONATAL FC-RECEPTOR | Animals | Transcytosis - physiology | Models, Biological | Humans | Kidney Tubules, Proximal - metabolism | Albuminuria - metabolism | Serum Albumin - metabolism | Index Medicus
Journal Article
The EMBO Journal, ISSN 0261-4189, 05/2001, Volume 20, Issue 9, pp. 2180 - 2190
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 4328 - 8
Journal Article
Kidney International, ISSN 0085-2538, 11/2013, Volume 84, Issue 5, pp. 902 - 910
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2003, Volume 100, Issue 14, pp. 8472 - 8477
Journal Article
Pediatric Nephrology, ISSN 0931-041X, 6/2015, Volume 30, Issue 6, pp. 1027 - 1031
The megalin/cubilin/amnionless complex is essential for albumin and low molecular weight (LMW) protein reabsorption by renal proximal tubules (PT). Mutations... 
Low-molecular-weight proteins | Pediatrics | Nephrology | Facio-oculo-acoustico-renal syndrome | Medicine & Public Health | Receptor-mediated endocytosis | Cubilin | Type 3 carbonic anhydrase | Megalin | Urology | CLC-5 | UROLOGY & NEPHROLOGY | PROTEINURIA | PEDIATRICS | MICE | CHLORIDE CHANNEL | Agenesis of Corpus Callosum - diagnosis | Immunohistochemistry | Predictive Value of Tests | Prognosis | Humans | Hearing Loss, Sensorineural - urine | Child, Preschool | Renal Tubular Transport, Inborn Errors - genetics | Carbonic Anhydrase III - urine | Endocytosis | Hearing Loss, Sensorineural - diagnosis | DNA Mutational Analysis | Agenesis of Corpus Callosum - genetics | Myopia - diagnosis | Proteinuria - urine | Renal Tubular Transport, Inborn Errors - urine | Hernias, Diaphragmatic, Congenital - urine | Female | Low Density Lipoprotein Receptor-Related Protein-2 - genetics | Proteinuria - diagnosis | Renal Tubular Transport, Inborn Errors - diagnosis | Renal Tubular Transport, Inborn Errors - physiopathology | Kidney Tubules, Proximal - ultrastructure | Kidney Tubules, Proximal - physiopathology | Genetic Predisposition to Disease | Receptors, Cell Surface - metabolism | Agenesis of Corpus Callosum - physiopathology | Hearing Loss, Sensorineural - genetics | Hernias, Diaphragmatic, Congenital - diagnosis | Proteinuria - genetics | Microscopy, Electron | Proteinuria - physiopathology | Myopia - genetics | Myopia - urine | Hernias, Diaphragmatic, Congenital - genetics | Phenotype | Myopia - physiopathology | Biopsy | Kidney Tubules, Proximal - metabolism | Mutation | Hernias, Diaphragmatic, Congenital - physiopathology | Agenesis of Corpus Callosum - urine | Hearing Loss, Sensorineural - physiopathology | Genetic disorders | Research | Analysis | Risk factors | Index Medicus
Journal Article