PLoS genetics, ISSN 1553-7390, 10/2018, Volume 14, Issue 10, p. e1007667
The role of host genetic variation in the development of complicated Staphylococcus aureus bacteremia (SAB) is poorly understood. We used whole exome...
MIGRATION | CELLS | POLYMORPHISMS | METABOLISM | GENOTYPE | SUSCEPTIBILITY | GENETICS & HEREDITY | FRAMEWORK | GENOME-WIDE | INFECTION | MUTATIONS | Genetic aspects | Genetic variation | Health aspects | Bacteremia | Staphylococcus aureus infections | Analysis | Nitric oxide | Genes | Genomics | Genetic research | Genetic transcription | Staphylococcus aureus | Glutamine | Transcription | Infections | Genomes | Parasites | Macrophages | Fungi | Cell activation | Interleukin 1 | Genetics | Bacteria | Cardiology | Bioinformatics | Supervision | CRISPR | Genetic diversity | Gene expression | Medicine | Infectious diseases | Hospitals | DNA microarrays | Endocarditis | Replication | Clinical medicine
MIGRATION | CELLS | POLYMORPHISMS | METABOLISM | GENOTYPE | SUSCEPTIBILITY | GENETICS & HEREDITY | FRAMEWORK | GENOME-WIDE | INFECTION | MUTATIONS | Genetic aspects | Genetic variation | Health aspects | Bacteremia | Staphylococcus aureus infections | Analysis | Nitric oxide | Genes | Genomics | Genetic research | Genetic transcription | Staphylococcus aureus | Glutamine | Transcription | Infections | Genomes | Parasites | Macrophages | Fungi | Cell activation | Interleukin 1 | Genetics | Bacteria | Cardiology | Bioinformatics | Supervision | CRISPR | Genetic diversity | Gene expression | Medicine | Infectious diseases | Hospitals | DNA microarrays | Endocarditis | Replication | Clinical medicine
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2009, Volume 4, Issue 10, pp. e7419 - e7419
Background: The two inflammatory molecules, S100A8 and S100A9, form a heterodimer, calprotectin. Plasma calprotectin levels are elevated in various...
MULTIDISCIPLINARY SCIENCES | Body Mass Index | Multivariate Analysis | Cross-Sectional Studies | Humans | Leukocyte L1 Antigen Complex - metabolism | Middle Aged | Male | Muscle, Skeletal - metabolism | Inflammation | Diabetes Mellitus, Type 2 - metabolism | Leukocyte L1 Antigen Complex - blood | Obesity - blood | Obesity - metabolism | Diabetes Mellitus, Type 2 - blood | Female | Dimerization | Neutrophils - metabolism | Smoking | Type 2 diabetes | Muscles | Obesity | RNA | Plasma | Health sciences | Genomes | Arthritis | mRNA | Proteins | Quality | Rodents | Infrared radiation | Tumor necrosis factor-TNF | Diabetes mellitus | Regression analysis | Tumor necrosis factor-α | Metabolism | Variance analysis | Skeletal muscle | Musculoskeletal system | Physical fitness | Infectious diseases | Brain-derived neurotrophic factor | Body mass | Insulin resistance | Diabetes | Autoimmune diseases | Plasmas (physics) | Fitness
MULTIDISCIPLINARY SCIENCES | Body Mass Index | Multivariate Analysis | Cross-Sectional Studies | Humans | Leukocyte L1 Antigen Complex - metabolism | Middle Aged | Male | Muscle, Skeletal - metabolism | Inflammation | Diabetes Mellitus, Type 2 - metabolism | Leukocyte L1 Antigen Complex - blood | Obesity - blood | Obesity - metabolism | Diabetes Mellitus, Type 2 - blood | Female | Dimerization | Neutrophils - metabolism | Smoking | Type 2 diabetes | Muscles | Obesity | RNA | Plasma | Health sciences | Genomes | Arthritis | mRNA | Proteins | Quality | Rodents | Infrared radiation | Tumor necrosis factor-TNF | Diabetes mellitus | Regression analysis | Tumor necrosis factor-α | Metabolism | Variance analysis | Skeletal muscle | Musculoskeletal system | Physical fitness | Infectious diseases | Brain-derived neurotrophic factor | Body mass | Insulin resistance | Diabetes | Autoimmune diseases | Plasmas (physics) | Fitness
Journal Article
Transfusion, ISSN 0041-1132, 09/2019, Volume 59, Issue 9, pp. 2776 - 2782
Fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridioides difficile infection and is potentially beneficial in other...
TRIAL | COLONOSCOPY | CLOSTRIDIUM-DIFFICILE INFECTION | FECAL MICROBIOTA TRANSPLANTATION | INTESTINAL MICROBIOTA | UPDATE | ACTIVE ULCERATIVE-COLITIS | DONOR FECES | FROZEN | HEMATOLOGY | INSULIN SENSITIVITY | Microbiota (Symbiotic organisms) | Blood banks | Blood donors | Microbiota | Blood & organ donations | Recurrent infection | Legislation | Infrastructure | Transplantation | Feces | Blood | How Do I?
TRIAL | COLONOSCOPY | CLOSTRIDIUM-DIFFICILE INFECTION | FECAL MICROBIOTA TRANSPLANTATION | INTESTINAL MICROBIOTA | UPDATE | ACTIVE ULCERATIVE-COLITIS | DONOR FECES | FROZEN | HEMATOLOGY | INSULIN SENSITIVITY | Microbiota (Symbiotic organisms) | Blood banks | Blood donors | Microbiota | Blood & organ donations | Recurrent infection | Legislation | Infrastructure | Transplantation | Feces | Blood | How Do I?
Journal Article
Journal of Medical Virology, ISSN 0146-6615, 10/2016, Volume 88, Issue 10, pp. 1653 - 1654
Journal Article
Diabetes, ISSN 0012-1797, 11/2008, Volume 57, Issue 11, pp. 3078 - 3082
OBJECTIVE-YKL-40 is produced by macrophages, and plasma YKL-40 is elevated in patients with diseases characterized by inflammation. In the present study,...
GP38K | OBESITY | HUMAN CARTILAGE GP-39 | INSULIN-RESISTANCE | ENDOCRINOLOGY & METABOLISM | CHITINASE PROTEIN FAMILY | NECROSIS-FACTOR-ALPHA | SMOOTH-MUSCLE-CELLS | ACCUMULATION | MAMMALIAN MEMBER | ADIPOSE-TISSUE | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Male | RNA, Messenger - metabolism | Antigens, CD - genetics | Case-Control Studies | Chitinase-3-Like Protein 1 | Adipose Tissue - metabolism | Adult | Female | Body Mass Index | Glycoproteins - genetics | Cross-Sectional Studies | RNA, Messenger - genetics | Glycoproteins - blood | Biomarkers - blood | Adipokines | Reverse Transcriptase Polymerase Chain Reaction | Antigens, Differentiation, Myelomonocytic - genetics | Diabetes Mellitus, Type 2 - diagnosis | Regression Analysis | Diabetes Mellitus, Type 2 - blood | Lectins | Glucose Clamp Technique | Blood Glucose - metabolism | Type 2 diabetes | Usage | Diagnosis | Biological markers | Pathophysiology
GP38K | OBESITY | HUMAN CARTILAGE GP-39 | INSULIN-RESISTANCE | ENDOCRINOLOGY & METABOLISM | CHITINASE PROTEIN FAMILY | NECROSIS-FACTOR-ALPHA | SMOOTH-MUSCLE-CELLS | ACCUMULATION | MAMMALIAN MEMBER | ADIPOSE-TISSUE | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Male | RNA, Messenger - metabolism | Antigens, CD - genetics | Case-Control Studies | Chitinase-3-Like Protein 1 | Adipose Tissue - metabolism | Adult | Female | Body Mass Index | Glycoproteins - genetics | Cross-Sectional Studies | RNA, Messenger - genetics | Glycoproteins - blood | Biomarkers - blood | Adipokines | Reverse Transcriptase Polymerase Chain Reaction | Antigens, Differentiation, Myelomonocytic - genetics | Diabetes Mellitus, Type 2 - diagnosis | Regression Analysis | Diabetes Mellitus, Type 2 - blood | Lectins | Glucose Clamp Technique | Blood Glucose - metabolism | Type 2 diabetes | Usage | Diagnosis | Biological markers | Pathophysiology
Journal Article
BULLETIN OF THE WORLD HEALTH ORGANIZATION, ISSN 0042-9686, 12/2014, Volume 92, Issue 12, pp. 909 - 914
Problem The introduction of antiretroviral therapy (ART) for HIV infection in sub-Saharan Africa has improved the quality of life of millions of people and...
MORTALITY | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | ANTIRETROVIRAL THERAPY | HIV-1-INFECTED PATIENTS | PREVALENCE | Delivery of Health Care - organization & administration | Humans | Middle Aged | Cooperative Behavior | Male | International Cooperation | Research | Guinea-Bissau | Anti-Retroviral Agents - administration & dosage | Adult | Female | HIV Infections - drug therapy | Community Health Centers | Anti-Retroviral Agents - supply & distribution | Cohort Studies | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Mortality | Developing countries--LDCs | Lessons from the Field
MORTALITY | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | ANTIRETROVIRAL THERAPY | HIV-1-INFECTED PATIENTS | PREVALENCE | Delivery of Health Care - organization & administration | Humans | Middle Aged | Cooperative Behavior | Male | International Cooperation | Research | Guinea-Bissau | Anti-Retroviral Agents - administration & dosage | Adult | Female | HIV Infections - drug therapy | Community Health Centers | Anti-Retroviral Agents - supply & distribution | Cohort Studies | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Mortality | Developing countries--LDCs | Lessons from the Field
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 6, p. e99971
Background: Co-infection with human immunodeficiency virus (HIV) and hepatitis B virus (HBV) may lead to accelerated hepatic disease progression with higher...
COTE-DIVOIRE | MULTIDISCIPLINARY SCIENCES | DISEASE BURDEN | CLINICAL-IMPLICATIONS | PREGNANT-WOMEN | C VIRUS | GENOTYPE-E | NATURAL-HISTORY | HBV | TREATMENT-NAIVE PATIENTS | EPIDEMIOLOGY | Guinea-Bissau - epidemiology | Hepatitis D - complications | Prevalence | HIV Infections - epidemiology | Humans | Middle Aged | Hepatitis B - virology | Hepatitis B - epidemiology | Male | Hepatitis B - blood | Hepatitis B - complications | Adult | Female | Cross-Sectional Studies | HIV Infections - virology | Hepatitis D - virology | Hepatitis Delta Virus - physiology | Risk Factors | Hepatitis D - epidemiology | Hepatitis B Surface Antigens - immunology | Coinfection - epidemiology | Mutation - genetics | Coinfection - virology | Hepatitis B virus - physiology | HIV Infections - complications | Hepatitis B virus - genetics | Medical research | Medical examination | RNA | Liver | Mortality | HIV patients | Development and progression | Lamivudine | HIV (Viruses) | Blood | Infection | Highly active antiretroviral therapy | Medicine, Experimental | Comparative analysis | Health aspects | HIV infection | Liver cirrhosis | Hepatitis B | Medical services | Chronic infection | Viruses | Infections | Serology | Drug resistance | Hepatitis | Genotype & phenotype | Antiretroviral agents | Human immunodeficiency virus--HIV | Superinfection | Hepatitis B virus | Cross sections | Public health | Deoxyribonucleic acid--DNA | Hepatitis delta virus | Antiretroviral drugs | Liver diseases | Hepatitis B surface antigen | Medical treatment | Religion | Regression analysis | Ribonucleic acid--RNA | Patients | CD4 antigen | Studies | Hepatitis B e antigen | Cirrhosis | Immunosuppression | Hospitals | Infectious diseases | Genotyping | Data collection | Mutation | Viral infections | Deoxyribonucleic acid | Ribonucleic acid | HIV | DNA | Human immunodeficiency virus
COTE-DIVOIRE | MULTIDISCIPLINARY SCIENCES | DISEASE BURDEN | CLINICAL-IMPLICATIONS | PREGNANT-WOMEN | C VIRUS | GENOTYPE-E | NATURAL-HISTORY | HBV | TREATMENT-NAIVE PATIENTS | EPIDEMIOLOGY | Guinea-Bissau - epidemiology | Hepatitis D - complications | Prevalence | HIV Infections - epidemiology | Humans | Middle Aged | Hepatitis B - virology | Hepatitis B - epidemiology | Male | Hepatitis B - blood | Hepatitis B - complications | Adult | Female | Cross-Sectional Studies | HIV Infections - virology | Hepatitis D - virology | Hepatitis Delta Virus - physiology | Risk Factors | Hepatitis D - epidemiology | Hepatitis B Surface Antigens - immunology | Coinfection - epidemiology | Mutation - genetics | Coinfection - virology | Hepatitis B virus - physiology | HIV Infections - complications | Hepatitis B virus - genetics | Medical research | Medical examination | RNA | Liver | Mortality | HIV patients | Development and progression | Lamivudine | HIV (Viruses) | Blood | Infection | Highly active antiretroviral therapy | Medicine, Experimental | Comparative analysis | Health aspects | HIV infection | Liver cirrhosis | Hepatitis B | Medical services | Chronic infection | Viruses | Infections | Serology | Drug resistance | Hepatitis | Genotype & phenotype | Antiretroviral agents | Human immunodeficiency virus--HIV | Superinfection | Hepatitis B virus | Cross sections | Public health | Deoxyribonucleic acid--DNA | Hepatitis delta virus | Antiretroviral drugs | Liver diseases | Hepatitis B surface antigen | Medical treatment | Religion | Regression analysis | Ribonucleic acid--RNA | Patients | CD4 antigen | Studies | Hepatitis B e antigen | Cirrhosis | Immunosuppression | Hospitals | Infectious diseases | Genotyping | Data collection | Mutation | Viral infections | Deoxyribonucleic acid | Ribonucleic acid | HIV | DNA | Human immunodeficiency virus
Journal Article
Lancet HIV, The, ISSN 2352-3018, 2014, Volume 1, Issue 1, pp. e13 - e21
Summary Background Activating the expression of latent virus is an approach that might form part of an HIV cure. We assessed the ability of the histone...
Infectious Disease | INFECTIOUS DISEASES | ACTIVATION | REPLICATION | RESERVOIR | ACID | VIVO | IMMUNOLOGY | EXPRESSION | T-CELLS | VORINOSTAT
Infectious Disease | INFECTIOUS DISEASES | ACTIVATION | REPLICATION | RESERVOIR | ACID | VIVO | IMMUNOLOGY | EXPRESSION | T-CELLS | VORINOSTAT
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, p. e0164220
Introduction The aim of this study was to examine whether low-grade inflammation (LGI) is associated with a subsequently increased risk of infection. Methods...
C-REACTIVE PROTEIN | DISTRIBUTIONS | WOMEN | OBESITY | QUALITY | INCREASED RISK | PREDICTORS | MULTIDISCIPLINARY SCIENCES | CARDIOVASCULAR-DISEASE | MARKERS | LIFE | International Classification of Diseases | Disease Susceptibility | Communicable Diseases - epidemiology | Humans | Middle Aged | Proportional Hazards Models | Hospitalization - statistics & numerical data | Male | Inflammation - epidemiology | Sex Characteristics | Young Adult | Blood Donors | Inflammation - complications | Inflammation - metabolism | C-Reactive Protein - metabolism | Adolescent | Denmark - epidemiology | Adult | Female | Aged | C-reactive protein | Analysis | Urinary tract infections | Anti-infective agents | Disease susceptibility | Inflammation | Blood donors | Pneumonia | Risk | Alcohol | Cardiovascular disease | Infections | Urinary tract | Metabolic syndrome | Epidemiology | Blood | Inflammatory diseases | Proteins | Confidence intervals | Mens health | Immunology | Population | Mathematical models | Obesity | Statistical analysis | Blood & organ donations | Health risks | Antimicrobial agents | Studies | Birth control | Weight control | Hospitals | Womens health | Rheumatoid arthritis | Men | Abscesses | Skin | Lymphomas | Lifestyles | Diabetes | Health risk assessment | Hazard assessment | Smoking | Cancer
C-REACTIVE PROTEIN | DISTRIBUTIONS | WOMEN | OBESITY | QUALITY | INCREASED RISK | PREDICTORS | MULTIDISCIPLINARY SCIENCES | CARDIOVASCULAR-DISEASE | MARKERS | LIFE | International Classification of Diseases | Disease Susceptibility | Communicable Diseases - epidemiology | Humans | Middle Aged | Proportional Hazards Models | Hospitalization - statistics & numerical data | Male | Inflammation - epidemiology | Sex Characteristics | Young Adult | Blood Donors | Inflammation - complications | Inflammation - metabolism | C-Reactive Protein - metabolism | Adolescent | Denmark - epidemiology | Adult | Female | Aged | C-reactive protein | Analysis | Urinary tract infections | Anti-infective agents | Disease susceptibility | Inflammation | Blood donors | Pneumonia | Risk | Alcohol | Cardiovascular disease | Infections | Urinary tract | Metabolic syndrome | Epidemiology | Blood | Inflammatory diseases | Proteins | Confidence intervals | Mens health | Immunology | Population | Mathematical models | Obesity | Statistical analysis | Blood & organ donations | Health risks | Antimicrobial agents | Studies | Birth control | Weight control | Hospitals | Womens health | Rheumatoid arthritis | Men | Abscesses | Skin | Lymphomas | Lifestyles | Diabetes | Health risk assessment | Hazard assessment | Smoking | Cancer
Journal Article
Transfusion, ISSN 0041-1132, 06/2019, Volume 59, Issue 6, pp. 2030 - 2038
BACKGROUND Blood donors are at increased risk of developing iron deficiency, and several studies have recommended iron supplementation for this group. The aim...
HEMOGLOBIN | HEMATOLOGY | GUT MICROBIOME | PREDICTORS | DISEASE | CHILDREN | Anti-infective agents | Usage | Postmenopausal women | Health aspects | Blood donors | Nutrient deficiency | Statistical analysis | Blood & organ donations | Dietary supplements | Health risks | Risk | Antimicrobial agents | Infections | Hazards | Iron | Blood | Post-menopause | Confidence intervals | Organic chemistry | Population (statistical) | Statistical models | Safety engineering | Mathematical models | Supplementation | Physical growth
HEMOGLOBIN | HEMATOLOGY | GUT MICROBIOME | PREDICTORS | DISEASE | CHILDREN | Anti-infective agents | Usage | Postmenopausal women | Health aspects | Blood donors | Nutrient deficiency | Statistical analysis | Blood & organ donations | Dietary supplements | Health risks | Risk | Antimicrobial agents | Infections | Hazards | Iron | Blood | Post-menopause | Confidence intervals | Organic chemistry | Population (statistical) | Statistical models | Safety engineering | Mathematical models | Supplementation | Physical growth
Journal Article
Gastroenterology, ISSN 0016-5085, 04/2019, Volume 156, Issue 5, pp. 1324 - 1332.e3
Fecal microbiota transplantation (FMT) is recommended for treatment of recurrent infection (rCDI). We performed a single-center randomized trial to compare the...
Bacteria | Antibiotic | Comparison | Microbiome | UNITED-STATES | COLONOSCOPY | MULTICENTER | METAANALYSIS | DIARRHEA | OPEN-LABEL | DONORS | MORTALITY-RATES | VANCOMYCIN | FROZEN | GASTROENTEROLOGY & HEPATOLOGY | Relapse | Care and treatment | Microbiota (Symbiotic organisms) | Colonoscopy | Analysis | Fidaxomicin | Health aspects | Antibacterial agents | Diseases
Bacteria | Antibiotic | Comparison | Microbiome | UNITED-STATES | COLONOSCOPY | MULTICENTER | METAANALYSIS | DIARRHEA | OPEN-LABEL | DONORS | MORTALITY-RATES | VANCOMYCIN | FROZEN | GASTROENTEROLOGY & HEPATOLOGY | Relapse | Care and treatment | Microbiota (Symbiotic organisms) | Colonoscopy | Analysis | Fidaxomicin | Health aspects | Antibacterial agents | Diseases
Journal Article
Journal of Medical Virology, ISSN 0146-6615, 03/2016, Volume 88, Issue 3, pp. 367 - 368
diagnosis | HIV‐2 | HIV | rapid test | West;1;Africa | Africa | Rapid test | HIV-2 | Diagnosis | GUINEA-BISSAU | VIROLOGY | Clinical Laboratory Techniques - methods | HIV-1 - isolation & purification | HIV-2 - isolation & purification | Diagnostic Tests, Routine - methods | HIV Infections - diagnosis | HIV Infections - virology | Humans | HIV testing | HIV (Viruses) | Health aspects | HIV infection
Journal Article
CLINICAL EPIDEMIOLOGY, ISSN 1179-1349, 2019, Volume 11, pp. 885 - 900
Purpose: Staphylococcus aureus carriage poses an increased risk of S. aureus infection. The aim of this study was to investigate the colonization of S. aureus...
risk factors | MAJOR RISK-FACTOR | prospective cohort study | DETERMINANTS | VALIDATION | STREAM INFECTIONS | PREVALENCE | blood donor health | THROAT | epidemiology | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | colonization | BACTEREMIA | NASAL CARRIAGE | Staphylococcus aureus | HEALTH SURVEY | Medical research | Staphylococcus aureus infections | Mupirocin | Research | Epidemiology | Risk factors | Blood donors | Infection | Genetic markers | Exercise | Analysis | Medicine, Experimental | Health aspects | Pathogens | Staphylococcus infections | Nose | Penicillin | Blood donor health | Prospective cohort study | Colonization
risk factors | MAJOR RISK-FACTOR | prospective cohort study | DETERMINANTS | VALIDATION | STREAM INFECTIONS | PREVALENCE | blood donor health | THROAT | epidemiology | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | colonization | BACTEREMIA | NASAL CARRIAGE | Staphylococcus aureus | HEALTH SURVEY | Medical research | Staphylococcus aureus infections | Mupirocin | Research | Epidemiology | Risk factors | Blood donors | Infection | Genetic markers | Exercise | Analysis | Medicine, Experimental | Health aspects | Pathogens | Staphylococcus infections | Nose | Penicillin | Blood donor health | Prospective cohort study | Colonization
Journal Article
ISBT Science Series, ISSN 1751-2816, 02/2019, Volume 14, Issue 1, pp. 140 - 145
Emerging infectious diseases (EIDs) require vigilance from blood banks everywhere. As EIDs spread to new areas and populations, blood banks are forced to...
risk assessment | blood safety | screening | deferral | emerging infectious diseases | Zika
risk assessment | blood safety | screening | deferral | emerging infectious diseases | Zika
Journal Article