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Journal Article
Frontiers in Immunology, ISSN 1664-3224, 10/2018, Volume 9, p. 2449
Autocrine activation of the complement receptors C3aR and CD46 by complement activation components C3a and C3b produced through C3 cleavage by the protease... 
Cathepsin L | Complement | AEP | CD46 | Legumain | T cell | THYMOSIN-ALPHA | ANTIGEN PRESENTATION | legumain | IMMUNOLOGY | complement | cathepsin L | EXPRESSION | T-CELLS | Cathepsins | T cells | Research
Journal Article
Journal of Cardiac Failure, ISSN 1071-9164, 11/2018, Volume 24, Issue 11, pp. 753 - 762
We studied the relationship between resting heart rate (HR), chronotropic response to exercise, and clinical outcomes in patients with heart failure (HF)... 
heart failure | exercise | heart rate | chronotropic index | prognosis | CAPACITY | CARDIAC & CARDIOVASCULAR SYSTEMS | INHIBITION | INCOMPETENCE | LIMIT | OUTCOMES | ASSOCIATION | Heart failure | Heart | Medical research | Heart beat | Analysis | Cardiac patients | Physiological aspects | Medicine, Experimental | Development and progression | Cardiovascular agents
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2017, Volume 114, Issue 46, p. 12111
Cytokines critically control immune responses, but how regulatory programs are altered to allow T cells to differentially respond to distinct cytokine stimuli... 
CRISPR | Interleukin 2 receptors | Chromatin | Immune response | Cytokines | Genes | Stat3 protein | Lymphocytes T | Stat5 protein | Gene expression | Gene sequencing | Interleukin 2 | Lymphocytes | Interleukin 21 | Mutation | Binding sites | Genetic modification | Immune system
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2010, Volume 107, Issue 33, pp. 14733 - 14738
Journal Article
Science, ISSN 0036-8075, 06/2016, Volume 352, Issue 6292, pp. aad1210 - aad1210
Journal Article
Biography, ISSN 0162-4962, 2016, Volume 39, Issue 1, pp. 34 - 44
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2014, Volume 111, Issue 46, p. 16484
  Early growth response 2 (EGR2) transcription factor negatively regulates T-cell activation, in contrast to the positive regulation of this process by EGR1.... 
Rodents | Genes | Influenza | T cell receptors | Interferon | Gene expression
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2014, Volume 111, Issue 9, pp. 3508 - 3513
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2013, Volume 123, Issue 6, pp. 2604 - 2615
The inhibitory receptor programmed cell death 1 (PD-1) plays a major role in functional exhaustion of T cells during chronic infections and cancer, and recent... 
MEDICINE, RESEARCH & EXPERIMENTAL | HIV-INFECTION | IMMUNODEFICIENCY-VIRUS | NEGATIVE FEEDBACK-REGULATION | INTERLEUKIN-2 THERAPY | GENE-EXPRESSION | ANTIRETROVIRAL THERAPY | CHRONIC VIRAL-INFECTION | LOW-DOSE IL-2 | TUMOR-IMMUNOTHERAPY | IMMUNE EVASION | Lymphocytic choriomeningitis virus - immunology | Arenaviridae Infections - virology | Humans | Lymphocytic choriomeningitis virus - drug effects | T-Lymphocytes, Regulatory - immunology | Interleukin-2 - administration & dosage | Immunotherapy | Hyaluronan Receptors - metabolism | CD8-Positive T-Lymphocytes - metabolism | Female | Arenaviridae Infections - immunology | Antiviral Agents - pharmacology | Lymphocyte Activation | Mice, Inbred C57BL | Immunologic Factors - administration & dosage | Programmed Cell Death 1 Receptor - metabolism | Mice, Transgenic | Viremia - drug therapy | Antiviral Agents - administration & dosage | B7-H1 Antigen - immunology | Antibodies - pharmacology | Drug Synergism | Antibodies - administration & dosage | T-Lymphocytes, Regulatory - drug effects | Animals | B7-H1 Antigen - antagonists & inhibitors | Arenaviridae Infections - drug therapy | Viremia - virology | CD8-Positive T-Lymphocytes - virology | CD8-Positive T-Lymphocytes - drug effects | Interleukin-7 Receptor alpha Subunit - metabolism | Interleukin-2 - pharmacology | Viremia - immunology | Mice | CD8-Positive T-Lymphocytes - immunology | Viral Load - drug effects |