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Science, ISSN 0036-8075, 5/2011, Volume 332, Issue 6030, pp. 687 - 696
Flow cytometry is an essential tool for dissecting the functional complexity of hematopoiesis. We used single-cell "mass cytometry" to examine healthy human... 
T lymphocytes | Cytometry | Phosphorylation | RESEARCH ARTICLE | B lymphocytes | Stem cells | Cell lines | Bone marrow | Bone marrow cells | Cells | Hematopoietic stem cells | STEM-CELLS | ACTIVATION | LYMPHOCYTE | MULTIDISCIPLINARY SCIENCES | MYELOGENOUS LEUKEMIA | TYROSINE KINASE INHIBITOR | FLOW-CYTOMETRY | DASATINIB | IDENTIFICATION | QUANTITATIVE-ANALYSIS | SIGNALING NETWORKS | Lanthanoid Series Elements | Leukocytes, Mononuclear - metabolism | Flow Cytometry - methods | Humans | Antibodies | Lymphocyte Subsets - immunology | Lymphocyte Subsets - metabolism | T-Lymphocytes - metabolism | Hematopoiesis | Single-Cell Analysis - methods | T-Lymphocytes - drug effects | Bone Marrow Cells - immunology | Leukocytes, Mononuclear - immunology | Mass Spectrometry | Bone Marrow Cells - drug effects | B-Lymphocytes - metabolism | Dasatinib | Leukocytes, Mononuclear - drug effects | Cytokines - metabolism | Bone Marrow Cells - cytology | Lymphocyte Activation | Lymphocyte Subsets - drug effects | Immunophenotyping | Pyrimidines - pharmacology | Transition Elements | B-Lymphocytes - drug effects | Algorithms | B-Lymphocytes - immunology | Signal Transduction - drug effects | T-Lymphocytes - immunology | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | Antigens, Surface - analysis | Bone Marrow Cells - metabolism | Protein-Tyrosine Kinases - antagonists & inhibitors | Evaluation | Flow cytometry | Immune response | Research | Immunopharmacology | Methods
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 10770 - 10
Single-cell barcoding enables the combined processing and acquisition of multiple individual samples as one. This maximizes assay efficiency and eliminates... 
ANALYSIS REVEALS | IMMUNE | MASS-CYTOMETRY | VIRUS | CISPLATIN | MULTIDISCIPLINARY SCIENCES | CLASS-I | HIGH-DIMENSIONAL CYTOMETRY | EXPRESSION | PROGRESSION | Cytometry | Major histocompatibility complex | Sodium | Tumor cells | Platinum | Stem cells | Palladium
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2018, Volume 24, Issue 4, pp. 474 - 483
Journal Article
Cell, ISSN 0092-8674, 04/2014, Volume 157, Issue 3, pp. 714 - 725
Tissue regeneration is an orchestrated progression of cells from an immature state to a mature one, conventionally represented as distinctive cell subsets. A... 
MASS CYTOMETRY | BIOCHEMISTRY & MOLECULAR BIOLOGY | IMMUNOGLOBULIN | STAT5 | LYMPHOCYTES | MURINE | CELL BIOLOGY | STAT5 Transcription Factor - metabolism | B-Lymphocytes - cytology | Lymphopoiesis | Algorithms | Humans | Precursor Cells, B-Lymphoid - cytology | V(D)J Recombination | Interleukin-7 - metabolism | Analysis | Hematopoietic stem cells
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 2313 - 2313
Journal Article
Cancer Cell, ISSN 1535-6108, 09/2014, Volume 26, Issue 3, pp. 414 - 427
MYC proteins are major drivers of cancer yet are considered undruggable because their DNA binding domains are composed of two extended alpha helices with no... 
MECHANISM | ONCOLOGY | HISTONE H3 | PHOSPHORYLATION | N-MYC | DFG FLIP | MLN8237 | THERAPEUTIC TARGETS | A KINASE | NEUROBLASTOMA | SMALL-MOLECULE INHIBITOR | CELL BIOLOGY | Phosphorylation | Area Under Curve | Allosteric Regulation | Humans | Crystallography, X-Ray | Structure-Activity Relationship | Aurora Kinase A - antagonists & inhibitors | Aurora Kinase A - metabolism | Pyrimidines - chemistry | Aurora Kinase A - chemistry | Phenylurea Compounds - chemistry | Proteolysis | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | N-Myc Proto-Oncogene Protein | Phenylurea Compounds - pharmacokinetics | Neuroblastoma - pathology | Cell Survival - drug effects | Catalytic Domain | Oncogene Proteins - chemistry | Protein Structure, Secondary | Oncogene Proteins - metabolism | Models, Molecular | Nuclear Proteins - metabolism | Pyrimidines - pharmacology | Antineoplastic Agents - chemistry | Mice, SCID | Nuclear Proteins - chemistry | Xenograft Model Antitumor Assays | Animals | Tumor Burden - drug effects | Mice, Nude | Neuroblastoma - drug therapy | Cell Line, Tumor | Pyrimidines - pharmacokinetics | Mice, Inbred NOD | Mice | Phenylurea Compounds - pharmacology | Protein Processing, Post-Translational | S Phase Cell Cycle Checkpoints - drug effects | Proteins | DNA-ligand interactions | Analysis | Protein binding
Journal Article
Cytometry Part A, ISSN 1552-4922, 05/2013, Volume 83A, Issue 5, pp. 483 - 494
Mass cytometry uses atomic mass spectrometry combined with isotopically pure reporter elements to currently measure as many as 40 parameters per single cell.... 
phenotype | normalization | flow cytometry | mass cytometry | CyTOF | blood | PBMC | internal standards | Flow cytometry | Mass cytometry | Phenotype | Internal standards | Normalization | Blood | BIOCHEMICAL RESEARCH METHODS | CELL BIOLOGY | Algorithms | Mass spectrometry | Analysis | Stem cells
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Journal Article