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Cancer Epidemiology Biomarkers and Prevention, ISSN 1055-9965, 07/2017, Volume 26, Issue 7, pp. 1034 - 1042
Background: 1,3-Butadiene (BD) is an important carcinogen in tobacco smoke that undergoes metabolic activation to DNA-reactive epoxides. These species can be... 
SPRAGUE-DAWLEY RATS | BIOMARKERS | INHALATION TOXICITY | URINARY BUTADIENE | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | ONCOLOGY | SPECIES-DIFFERENCES | SYNTHETIC RUBBER INDUSTRY | BUTADIENE MONOEPOXIDE | CIGARETTE-SMOKE | HUMAN LIVER-MICROSOMES | EXPOSURE | Smoking - adverse effects | Biomarkers - urine | Lung Neoplasms - urine | Asian Americans - statistics & numerical data | Glutathione - metabolism | Humans | Middle Aged | Smokers - statistics & numerical data | Acetylcysteine - metabolism | Male | Carcinogens - metabolism | Glutathione Transferase - genetics | Acetylcysteine - analogs & derivatives | Gene Deletion | Female | Lung Neoplasms - genetics | Genome-Wide Association Study | Lung Neoplasms - enzymology | Risk Factors | Glutathione Transferase - metabolism | European Continental Ancestry Group - statistics & numerical data | Gene Dosage | Acetylcysteine - urine | Smoking - metabolism | African Americans - statistics & numerical data | Butadienes - metabolism | Aged | Polymorphism, Single Nucleotide | Smoking - urine | Metabolic rate | Cysteine | Copy number | Lung cancer | Acetylcysteine | Genomes | Single-nucleotide polymorphism | Smoke | Gene deletion | GSTT1 protein | Butadiene | Body mass index | Carcinogens | Metabolites | Measurement methods | Epoxides | GSTT1 gene | Genotypes | Deoxyribonucleic acid--DNA | Glutathione | Urine | Japanese Americans | Detoxification | Health risks | Metabolism | 1,3-Butadiene | Minority & ethnic groups | Tobacco | Body mass | Body size | Metabolic activation | Biomarkers | Determinants | N-Acetyl-L-cysteine | Conjugation | Nicotine | Smoking | Cancer | mass spectrometry | race | ethnicity | 1, 3-Butadiene | smoking | urinary metabolites
Journal Article
Journal Article
Journal Article
Chemical Research in Toxicology, ISSN 0893-228X, 07/2015, Volume 28, Issue 7, pp. 1496 - 1507
N-6-(2-Hydroxy-3-buten-1-yl)-2'-deoxyadenosine (N-6-HB-dA I) and N-6,N-6-(2,3-dihydroxybutan-1,4-diyl)-2'-deoxyadenosine (N-6,N-6-DHB-dA) are exocyclic DNA... 
CHEMISTRY, MEDICINAL | MUTATIONAL SPECTRUM | HUMAN DNA-POLYMERASE | TRANSLESION SYNTHESIS | HUMAN LIVER-MICROSOMES | INHALATION EXPOSURE | CHEMISTRY, MULTIDISCIPLINARY | IN-VITRO | ADENINE N-6 | EXOCYCLIC DEOXYADENOSINE ADDUCTS | 1,2,3,4-DIEPOXYBUTANE SYNTHESIS | TOXICOLOGY | LACI TRANSGENIC MICE
Journal Article
Chemical Research in Toxicology, ISSN 0893-228X, 07/2015, Volume 28, Issue 7, pp. 1496 - 1507
N 6 -(2-Hydroxy-3-buten-1-yl)-2′-deoxyadenosine (N 6 -HB-dA I) and N 6 , N 6 -(2,3-dihydroxybutan-1,4-diyl)-2′-deoxyadenosine (N 6 , N 6 -DHB-dA) are exocyclic... 
nucleic acid chemistry | DNA polymerase | mutagenesis mechanism | DNA damage | enzyme kinetics | mass spectrometry (MS)
Journal Article
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